Molecular Composition of Vestibular Hair Bundles.

The vertebrate hair bundle, responsible for transduction of mechanical signals into receptor potentials in sensory hair cells, is an evolutionary masterpiece. Composed of actin-filled stereocilia of precisely regulated length, width, and number, the structure of the hair bundle is optimized for sensing auditory and vestibular stimuli. Recent developments in identifying the lipids and proteins constituting the hair bundle, obtained through genetics, biochemistry, and imaging, now permit a description of the consensus composition of vestibular bundles of mouse, rat, and chick.

• Publication year

  2018

• Venue

  Cold Spring Harbor Perspectives in Medicine

• Publication date

  2018-05-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/cshperspect.a033209PMID 29844221PMCID PMC6314077
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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