Chronic light exposure alters serotonergic and orexinergic systems in the rat brain and reverses maternal separation-induced increase in orexin receptors in the prefrontal cortex

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Metabolic brain disease

• Publication date

  2018-04-01

• Fields of study

  Biology, Medicine, Chemistry, Psychology

• Identifiers
  DOI 10.1007/s11011-017-0123-0PMID 29039077
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Morning bright light therapy: a helpful tool for reducing comorbid symptoms of affective and behavioral dysregulation in juvenile depressed inpatients? A pilot trial.

  2017cited by this paper
• New directions for the treatment of depression: Targeting the photic regulation of arousal and mood (PRAM) pathway

  2017cited by this paper
• University of Groningen Effects of early life stress on adult male aggression and hypothalamic vasopressin and serotonin Veenema

  2017cited by this paper
• Role of the Orexin/Hypocretin System in Stress-Related Psychiatric Disorders.

  2017cited by this paper
• Effect of circadian rhythm disturbance on morphine preference and addiction in male rats: Involvement of period genes and dopamine D1 receptor.

  2016cited by this paper
• Comprehensive Behavioral Analysis of Male Ox1r−/− Mice Showed Implication of Orexin Receptor-1 in Mood, Anxiety, and Social Behavior

  2016cited by this paper
• Depletion of nucleus accumbens dopamine leads to impaired reward and aversion processing in mice: Relevance to motivation pathologies.

  2016cited by this paper
• Developmental stress and lead (Pb): Effects of maternal separation and/or Pb on corticosterone, monoamines, and blood Pb in rats.

  2016cited by this paper
• Comprehensive Behavioral Analysis of Male Ox1r−/− Mice Showed Implication of Orexin Receptor-1 in Mood, Anxiety, and Social Behavior

  2015cited by this paper
• Shining light on motivation, emotion, and memory processes

  2015cited by this paper
• Antidepressant effects of exercise are produced via suppression of hypocretin/orexin and melanin-concentrating hormone in the basolateral amygdala.

  2015cited by this paper
• Salvinorin-A Induces Intense Dissociative Effects, Blocking External Sensory Perception and Modulating Interoception and Sense of Body Ownership in Humans

  2015cited by this paper
• Early life social stress induced changes in depression and anxiety associated neural pathways which are correlated with impaired maternal care.

  2015cited by this paper
• Strain-Dependent Variations in Stress Coping Behavior Are Mediated by a 5-HT/GABA Interaction within the Prefrontal Corticolimbic System

  2015cited by this paper
• Social interaction with rat exposed to constant light during lactation prevents depressive-like behavior induced by constant light in adulthood.

  2015cited by this paper
• Chromosome 1 replacement increases brain orexins and antidepressive measures without increasing locomotor activity.

  2014cited by this paper
• Orexin administration to mice that underwent chronic stress produces bimodal effects on emotion-related behaviors.

  2014cited by this paper
• Neural Circuit Interactions between the Dorsal Raphe Nucleus and the Lateral Hypothalamus: An Experimental and Computational Study

  2014cited by this paper
• Prolonged maternal separation disturbs the serotonergic system during early brain development

  2014cited by this paper
• Motivational activation: a unifying hypothesis of orexin/hypocretin function

  2014cited by this paper
• Acquisition and expression of conditioned taste aversion differentially affects extracellular signal regulated kinase and glutamate receptor phosphorylation in rat prefrontal cortex and nucleus accumbens

  2014cited by this paper
• Orexin antagonists for neuropsychiatric disease: progress and potential pitfalls

  2014cited by this paper
• Increased number of orexin/hypocretin neurons with high and prolonged external stress-induced depression.

  2014cited by this paper
• Exercise reverses the effects of early life stress on orexin cell reactivity in male but not female rats

  2014influential reference
• Role of Orexin in the Pathophysiology of Depression: Potential for Pharmacological Intervention

  2013cited by this paper
• Maternal separation increases GABA(A) receptor-mediated modulation of norepinephrine release in the hippocampus of a rat model of ADHD, the spontaneously hypertensive rat.

  2013cited by this paper
• Maternal separation induces alterations of serotonergic system in different aged rats.

  2013cited by this paper
• Disruption of circadian rhythms due to chronic constant light leads to depressive and anxiety-like behaviors in the rat.

  2013cited by this paper
• Chronic Exposure to Light Reverses the Effect of Maternal Separation on Proteins in the Prefrontal Cortex

  2013cited by this paper
• Behavioral changes after maternal separation are reversed by chronic constant light treatment.

  2012influential reference
• The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus.

  2012cited by this paper
• Orexinergic signaling mediates light-induced neuronal activation in the dorsal raphe nucleus.

  2012influential reference
• Corticotropin-releasing factor in the nucleus accumbens shell induces swim depression, anxiety, and anhedonia along with changes in local dopamine/acetylcholine balance.

  2012cited by this paper
• Exercise normalizes altered expression of proteins in the ventral hippocampus of rats subjected to maternal separation

  2012cited by this paper
• Neonatal exposure to constant light prevents anhedonia-like behavior induced by constant light exposure in adulthood.

  2011cited by this paper
• Hcrtr1 and 2 signaling differentially regulates depression-like behaviors.

  2011influential reference
• Association between major mood disorders and the hypocretin receptor 1 gene.

  2011cited by this paper
• Activation of orexin neurons in dorsomedial/perifornical hypothalamus and antidepressant reversal in a rodent model of depression.

  2011influential reference
• Adolescent development, hypothalamic-pituitary-adrenal function, and programming of adult learning and memory.

  2010cited by this paper
• Mesolimbic dopaminergic activity responding to acute stress is blunted in adolescent rats that experienced neonatal maternal separation.

  2010cited by this paper
• Blue but not red light stimulation in the dark has antidepressant effect in behavioral despair.

  2009cited by this paper
• Orexin/Hypocretin: A Neuropeptide at the Interface of Sleep, Energy Homeostasis, and Reward System

  2009cited by this paper
• Behavioral despair is differentially affected by the length and timing of photic stimulation in the dark phase of an L/D cycle.

  2008cited by this paper
• Serotonin and depression: pathophysiological mechanism or marketing myth?

  2008cited by this paper
• Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression

  2008cited by this paper
• Treatment of circadian rhythm sleep disorders with light.

  2008cited by this paper
• Differential effect of environment enrichment and social isolation on depressive-like behavior, spontaneous activity and serotonin and norepinephrine concentration in prefrontal cortex and ventral striatum.

  2008cited by this paper
• Effects of maternal separation on hypothalamic-pituitary-adrenal responses, cognition and vulnerability to stress in adult female rats.

  2008cited by this paper
• Neuroplasticity in the mesolimbic dopamine system and cocaine addiction

  2008cited by this paper
• Types and functions of ultrasonic vocalizations in laboratory rats and mice.

  2007cited by this paper
• Brain orexins and wake regulation in rats exposed to maternal deprivation.

  2007cited by this paper
• The role of dopamine in the pathophysiology of depression.

  2007cited by this paper
• Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder.

  2007cited by this paper
• Exposure to chronic constant light impairs spatial memory and influences long-term depression in rats.

  2007cited by this paper
• Arousal and reward: a dichotomy in orexin function.

  2006cited by this paper
• Maternal Separation in Rats Leads to Anxiety-Like Behavior and a Blunted ACTH Response and Altered Neurotransmitter Levels in Response to a Subsequent Stressor

  2004influential reference
• In Vitro Glutamate-Stimulated Release of Dopamine from Nucleus Accumbens Core and Shell of Spontaneously Hypertensive Rats

  2003cited by this paper
• The physiology and pharmacology of the orexins.

  2002influential reference
• Expression of orexin-A and functional orexin type 2 receptors in the human adult adrenals: implications for adrenal function and energy homeostasis.

  2001cited by this paper
• Hypocretin-1 Modulates Rapid Eye Movement Sleep through Activation of Locus Coeruleus Neurons

  2000cited by this paper
• The role of accumbens dopamine in lever pressing and response allocation: effects of 6-OHDA injected into core and dorsomedial shell.

  1998cited by this paper
• The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.

  1998cited by this paper
• Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

  1998cited by this paper
• Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior.

  1998cited by this paper
• Comparative study in the rat of the actions of different types of stress on the release of 5-HT in raphe nuclei and forebrain areas.

  1997cited by this paper
• Seasonal affective disorder. A description of the syndrome and preliminary findings with light therapy.

  1984cited by this paper
• Endogenous ultradian rhythms in rats exposed to prolonged continuous light.

  1978cited by this paper

• Adolescent Nonpharmacological Interventions for Early-Life Stress and Their Mechanism.

  2023cites this paper
• Neurobiology of the Orexin System and Its Potential Role in the Regulation of Hedonic Tone

  2022cites this paper
• Compound Chaijin Jieyu Tablets ameliorating insomnia complicated with depression by improving synaptic plasticity via regulating orexin A, melatonin, and acetylcholine contents

  2022cites this paper
• Dysregulation of the orexinergic system: A potential neuropeptide target in depression.

  2020cites this paper
• Partial Improvement of Spatial Memory Damages by Bone Marrow Mesenchymal Stem Cells Transplantation Following Trimethyltin Chloride Administration in the Rat CA1

  2019cites this paper