Complement Inhibitor C4b-Binding Protein Interacts Directly with Small Glycoproteins of the Extracellular Matrix1

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Journal of Immunology

• Publication date

  2009-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.182.3.1518PMID 19155499
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Synovial fluid levels of complement SC5b-9 and fragment Bb are elevated in patients with rheumatoid arthritis.

  2010cited by this paper
• Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation.

  2009cited by this paper
• Native, amyloid fibrils and beta-oligomers of the C-terminal domain of human prion protein display differential activation of complement and bind C1q, factor H and C4b-binding protein directly.

  2008cited by this paper
• C4b-binding protein in Alzheimer's disease: binding to Abeta1-42 and to dead cells.

  2008cited by this paper
• C4b-binding Protein and Factor H Compensate for the Loss of Membrane-bound Complement Inhibitors to Protect Apoptotic Cells against Excessive Complement Attack*

  2007cited by this paper
• Interaction with C4b-Binding Protein Contributes to Nontypeable Haemophilus influenzae Serum Resistance1

  2007cited by this paper
• Interaction with C4b-binding protein contributes to non-typeable Haemophilus influenzae serum resistance

  2007cited by this paper
• Evaluation of classical complement pathway activation in rheumatoid arthritis: measurement of C1q-C4 complexes as novel activation products.

  2006cited by this paper
• Alternative Complement Pathway Activation Is Essential for Inflammation and Joint Destruction in the Passive Transfer Model of Collagen-Induced Arthritis1

  2006cited by this paper
• Evidence That Complement Protein C1q Interacts with C-Reactive Protein through Its Globular Head Region1

  2006cited by this paper
• Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein.

  2006cited by this paper
• The Extracellular Matrix and Inflammation

  2005cited by this paper
• The Extracellular Matrix and Inflammation FIBROMODULIN ACTIVATES THE CLASSICAL PATHWAY OF COMPLEMENT BY DIRECTLY BINDING C1q *

  2005cited by this paper
• C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation

  2005cited by this paper
• Interactions of the Extracellular Matrix Proteoglycans Decorin and Biglycan with C1q and Collectins1

  2005cited by this paper
• “Thiocyanate gold”: small (2–3 nm) colloidal gold for affinity cytochemical labeling in electron microscopy

  2004cited by this paper
• Identification of Tyrosine Sulfation in Extracellular Leucine-rich Repeat Proteins Using Mass Spectrometry*

  2004cited by this paper
• Functions of human complement inhibitor C4b-binding protein in relation to its structure.

  2004cited by this paper
• Complement activation by both classical and alternative pathways is critical for the effector phase of arthritis

  2004cited by this paper
• The C4b-binding Protein-Protein S Complex Inhibits the Phagocytosis of Apoptotic Cells*

  2004cited by this paper
• CCP1-4 of the C4b-binding protein alpha-chain are required for factor I mediated cleavage of complement factor C3b.

  2003cited by this paper
• Structural Requirements for the Complement Regulatory Activities of C4BP*

  2001cited by this paper
• Association of Chondroadherin with Collagen Type II*

  2001cited by this paper
• Differential Regulation of a and p Chains of C 4 b-Binding Protein During Acute-Phase Response Resulting in Stable Plasma Levels of Free Anticoagulant Protein S

  2000cited by this paper
• A Role for Complement in Antibody-Mediated Inflammation: C5-Deficient DBA/1 Mice Are Resistant to Collagen-Induced Arthritis

  2000cited by this paper
• A Cluster of Positively Charged Amino Acids in the C4BP α-Chain Is Crucial for C4b Binding and Factor I Cofactor Function*

  1999cited by this paper
• Regulation of complement activation by C-reactive protein: targeting the complement inhibitory activity of factor H by an interaction with short consensus repeat domains 7 and 8-11.

  1999cited by this paper
• Leucine-rich repeat glycoproteins of the extracellular matrix.

  1998cited by this paper
• Osteoadherin, a Cell-binding Keratan Sulfate Proteoglycan in Bone, Belongs to the Family of Leucine-rich Repeat Proteins of the Extracellular Matrix*

  1998cited by this paper
• Bone Matrix Proteins: Isolation and Characterization of a Novel Cell-binding Keratan Sulfate Proteoglycan (Osteoadherin) from Bovine Bone

  1998cited by this paper
• The Primary Structure of a Basic Leucine-rich Repeat Protein, PRELP, Found in Connective Tissues (*)

  1995cited by this paper
• Serum Amyloid P Component Binding to C4b-binding Protein (*)

  1995cited by this paper
• The structure of a 38-kDa leucine-rich protein (chondroadherin) isolated from bovine cartilage.

  1994cited by this paper
• Differential regulation of alpha and beta chains of C4b-binding protein during acute-phase response resulting in stable plasma levels of free anticoagulant protein S

  1994cited by this paper
• Cloning of cDNA coding for the beta chain of human complement component C4b-binding protein: sequence homology with the alpha chain.

  1990cited by this paper
• A collagen‐binding 59‐kd protein (fibromodulin) is structurally related to the small interstitial proteoglycans PG‐S1 and PG‐S2 (decorin).

  1989cited by this paper
• Electron microscopy and other physical methods for the characterization of extracellular matrix components: laminin, fibronectin, collagen IV, collagen VI, and proteoglycans.

  1987cited by this paper
• An analysis of the levels of complement components in the synovial fluid in rheumatic diseases

  1987cited by this paper
• Two novel matrix proteins isolated from articular cartilage show wide distributions among connective tissues.

  1986cited by this paper
• Molecular cloning and characterization of the cDNA coding for C4b-binding protein, a regulatory protein of the classical pathway of the human complement system.

  1985cited by this paper
• The C1q subunit of the first component of complement binds to laminin: a mechanism for the deposition and retention of immune complexes in basement membrane.

  1985cited by this paper
• Characterization of the interaction of human C4b-binding protein with physiological ligands.

  1984cited by this paper
• Purification of human C4b-binding protein and formation of its complex with vitamin K-dependent protein S.

  1983cited by this paper
• Fibronectin binds to the C1q component of complement.

  1982cited by this paper
• High molecular weight complex in human plasma between vitamin K-dependent protein S and complement component C4b-binding protein.

  1981cited by this paper
• Modulation of the classical pathway C3 convertase by plasma proteins C4 binding protein and C3b inactivator.

  1979cited by this paper
• Human C4-binding protein. I. Isolation and characterization

  1978cited by this paper
• Cloning of cDNA coding for the f8 chain of human complement component C4b-binding protein: Sequence homology with the a chain

  year unknowncited by this paper

• Osteomodulin modulates the inflammatory responses via the interleukin-1 receptor 1/nuclear factor-κB signaling pathway in dental pulpitis

  2025cites this paper
• Beyond the Norm: The emerging interplay of complement system and extracellular matrix in the tumor microenvironment.

  2025cites this paper
• Molecular cues for immune cells from small leucine-rich repeat proteoglycans in their extracellular matrix-associated and free forms.

  2023cites this paper
• The role of fibromodulin in inflammatory responses and diseases associated with inflammation

  2023cites this paper
• Exploring the function of factor XIII free B subunit: Interactions with complement factors and a novel approach to identify potential binding partners

  2022cites this paper
• Interaction of Streptococcus pyogenes with extracellular matrix components resulting in immunomodulation and bacterial eradication

  2020cites this paper
• Communications via the Small Leucine-rich Proteoglycans: Molecular Specificity in Inflammation and Autoimmune Diseases

  2020cites this paper
• Plasma C4d Correlates With C4d Deposition in Kidneys and With Treatment Response in Lupus Nephritis Patients

  2020cites this paper
• Complement activation and regulation in rheumatic disease.

  2019cites this paper
• Novel potential inhibitors of complement system and their roles in complement regulation and beyond.

  2018cites this paper
• Short Leucine-Rich Proteoglycans Modulate Complement Activity and Increase Killing of the Respiratory Pathogen Moraxella catarrhalis

  2018cites this paper
• Cartilage oligomeric matrix protein promotes prostate cancer progression by enhancing invasion and disrupting intracellular calcium homeostasis

  2017cites this paper
• PRELP Enhances Host Innate Immunity against the Respiratory Tract Pathogen Moraxella catarrhalis

  2017cites this paper
• Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

  2017cites this paper
• Small leucine-rich repeat proteoglycans in corneal inflammation and wound healing.

  2016cites this paper
• C4b-binding protein: The good, the bad and the deadly. Novel functions of an old friend.

  2016cites this paper
• Complement factor H in host defense and immune evasion

  2016cites this paper
• The leucine-rich repeat protein PRELP binds fibroblast cell-surface proteoglycans and enhances focal adhesion formation.

  2016cites this paper
• The small leucine‐rich repeat proteoglycans in tissue repair and atherosclerosis

  2015cites this paper
• The Plasmodium falciparum blood stages acquire factor H family proteins to evade destruction by human complement

  2015cites this paper
• Fibromodulin and Dystrophin in Atherosclerosis: Novel roles for extracellular matrix in plaque development

  2014cites this paper
• Mecanismos de Evasão do Sistema Complemento por Leptospira ssp.: Interação com o Inibidor de C1 Esterase e C4BP

  2014cites this paper
• Biomarkers and proteomic analysis of osteoarthritis.

  2014cites this paper
• Purification and functional characterization of C4b-binding protein (C4BP).

  2014cites this paper
• Female-Specific Hypertension Loci on Rat Chromosome 13

  2013cites this paper
• Sushi domain‐containing protein 4 (SUSD4) inhibits complement by disrupting the formation of the classical C3 convertase

  2013cites this paper
• The novel complement inhibitor human CUB and Sushi multiple domains 1 (CSMD1) protein promotes factor I‐mediated degradation of C4b and C3b and inhibits the membrane attack complex assembly

  2013cites this paper
• Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

  2012cites this paper
• PRELP Protein Inhibits the Formation of the Complement Membrane Attack Complex*

  2012influential citation
• The Different Roles of Aggrecan Interaction Domains

  2012cites this paper
• Complement in the immunopathogenesis of rheumatic disease

  2012cites this paper
• Interactions of the complement system with molecules of extracellular matrix: relevance for joint diseases.

  2012cites this paper
• Early Complementopathy After Multiple Injuries in Humans

  2012cites this paper
• The C-Type Lectin of the Aggrecan G3 Domain Activates Complement

  2012cites this paper
• Heavy Chains of Inter Alpha Inhibitor (IαI) Inhibit the Human Complement System at Early Stages of the Cascade*

  2012cites this paper
• Gene Therapy in the Treatment of Knee Disorders

  2012cites this paper
• Transcriptional Modulation in a Leukocyte-Depleted Splenic Cell Population During Prion Disease

  2011cites this paper
• The role of higher-order protein structure in supporting binding by heteroclitic monoclonal antibodies: the monoclonal antibody KIM185 to CD18 also binds C4-binding protein.

  2011cites this paper
• Human Pentraxin 3 Binds to the Complement Regulator C4b-Binding Protein

  2011cites this paper
• NC4 Domain of Cartilage-specific Collagen IX Inhibits Complement Directly Due to Attenuation of Membrane Attack Formation and Indirectly through Binding and Enhancing Activity of Complement Inhibitors C4B-binding Protein and Factor H*

  2011cites this paper
• C4BPB/C4BPA is a new susceptibility locus for venous thrombosis with unknown protein S-independent mechanism: results from genome-wide association and gene expression analyses followed by case-control studies.

  2010cites this paper
• Cancer and the Complement Cascade

  2010cites this paper
• Towards New Therapeutic Targets: Identification of Novel Tumor Markers in Chronic Lymphocytic Leukemia

  2010cites this paper
• Inflammation and Complement Activation in Intracranial Artery Aneurysms

  2010cites this paper
• Development of a Murine model to dissect the CpG-oligonucleotide-enhancement of the killing of human B Cells by rituximab.

  2010cites this paper
• Lack of complement inhibitors in the outer intracranial artery aneurysm wall associates with complement terminal pathway activation.

  2010cites this paper
• Regulation of complement by cartilage oligomeric matrix protein allows for a novel molecular diagnostic principle in rheumatoid arthritis.

  2010cites this paper
• Annexin-II, DNA, and Histones Serve as Factor H Ligands on the Surface of Apoptotic Cells

  2009cites this paper
• The Articular Cartilage

  2008cites this paper