COMT and DAT1 genes are associated with hyperactivity and inattention traits in the 1993 Pelotas Birth Cohort: evidence of sex-specific combined effect.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Psychiatry & Neuroscience

• Publication date

  2016-06-21

• Fields of study

  Medicine, Psychology

• Identifiers
  DOI 10.1503/JPN.150270PMID 27327562PMCID PMC5082511
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Gently restless: association of ADHD-like traits with response inhibition and interference control

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• Mechanisms underpinning inattention and hyperactivity: neurocognitive support for ADHD dimensionality

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• Distinct frontal lobe morphology in girls and boys with ADHD

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• Functional effects of dopamine transporter gene genotypes on in vivo dopamine transporter functioning: a meta-analysis

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• Effects of estrogen on higher-order cognitive functions in unstressed human females may depend on individual variation in dopamine baseline levels

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• ADHD in DSM-5: a field trial in a large, representative sample of 18- to 19-year-old adults

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• Glutamatergic copy number variants and their role in attention‐deficit/hyperactivity disorder

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• No Genetic Influence for Childhood Behavior Problems From DNA Analysis

  2013cited by this paper
• Trajectories of cerebral cortical development in childhood and adolescence and adult attention-deficit/hyperactivity disorder.

  2013cited by this paper
• Candidate genetic pathways for attention-deficit/hyperactivity disorder (ADHD) show association to hyperactive/impulsive symptoms in children with ADHD.

  2013cited by this paper
• Childhood attention-deficit hyperactivity disorder as an extreme of a continuous trait: a quantitative genetic study of 8,500 twin pairs.

  2012cited by this paper
• Cathechol-O-methyltransferase Val158Met polymorphism is associated with disruptive behavior disorders among children and adolescents with ADHD

  2012cited by this paper
• Gene–environment interaction in externalizing problems among adolescents: evidence from the Pelotas 1993 Birth Cohort Study

  2012cited by this paper
• Evidence-based psychiatric genetics, AKA the false dichotomy between common and rare variant hypotheses

  2012cited by this paper
• Cortical development in typically developing children with symptoms of hyperactivity and impulsivity: support for a dimensional view of attention deficit hyperactivity disorder.

  2011cited by this paper
• Relationship between SLC6A3 genotype and striatal dopamine transporter availability: A meta‐analysis of human single photon emission computed tomography studies

  2011cited by this paper
• Genotype link with extreme antisocial behavior: the contribution of cognitive pathways.

  2010cited by this paper
• Attention-deficit/hyperactivity disorder and the dopaminergic hypotheses

  2010cited by this paper
• Variation in the catechol-O-methyltransferase Val158Met polymorphism associated with conduct disorder and ADHD symptoms, among adolescent male delinquents

  2010cited by this paper
• Meta-analysis of genome-wide association studies of attention-deficit/hyperactivity disorder.

  2010cited by this paper
• Psychopathy traits in adolescents with childhood attention-deficit hyperactivity disorder

  2009cited by this paper
• Association between Catechol O‐methyltransferase (COMT) haplotypes and severity of hyperactivity symptoms in Adults

  2009cited by this paper
• Candidate gene studies of ADHD: a meta-analytic review

  2009cited by this paper
• Attention Deficit Hyperactivity Disorder comorbid oppositional defiant disorder and its predominately inattentive type: evidence for an association with COMT but not MAOA in a Chinese sample

  2009cited by this paper
• Genetic risk for conduct disorder symptom subtypes in an ADHD sample: specificity to aggressive symptoms.

  2009cited by this paper
• Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: A preliminary study

  2008cited by this paper
• A replicated molecular genetic basis for subtyping antisocial behavior in children with attention-deficit/hyperactivity disorder.

  2008cited by this paper
• genepop’007: a complete re‐implementation of the genepop software for Windows and Linux

  2008cited by this paper
• Cohort profile: the 1993 Pelotas (Brazil) birth cohort study.

  2008cited by this paper
• Interaction of dopamine transporter genotype with prenatal smoke exposure on ADHD symptoms.

  2008cited by this paper
• A meta‐analysis of association studies between the 10‐repeat allele of a VNTR polymorphism in the 3′‐UTR of dopamine transporter gene and attention deficit hyperactivity disorder

  2007cited by this paper
• Contributions of the DAT1 and DRD2 genes to serious and violent delinquency among adolescents and young adults

  2007cited by this paper
• Sexual dimorphism of brain developmental trajectories during childhood and adolescence

  2007cited by this paper
• G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences

  2007cited by this paper
• Consequences of variations in genes that affect dopamine in prefrontal cortex.

  2007cited by this paper
• Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children.

  2007cited by this paper
• Relationship between VNTR polymorphisms of the human dopamine transporter gene and expression in post‐mortem midbrain tissue

  2007cited by this paper
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  2006cited by this paper
• Sex differences in striatal dopamine release in healthy adults.

  2006cited by this paper
• Methodological aspects of the 1993 Pelotas (Brazil) Birth Cohort Study.

  2006cited by this paper
• Molecular genetics of attention-deficit/hyperactivity disorder.

  2005influential reference
• BMC Medical Genetics BioMed Central

  2005cited by this paper
• Association of the dopamine transporter (DAT1) 10/10-repeat genotype with ADHD symptoms and response inhibition in a general population sample

  2005cited by this paper
• The age-dependent decline of attention deficit hyperactivity disorder: a meta-analysis of follow-up studies

  2005cited by this paper
• Quantitative trait locus analysis of candidate gene alleles associated with attention deficit hyperactivity disorder (ADHD) in five genes: DRD4, DAT1, DRD5, SNAP‐25, and 5HT1B

  2005cited by this paper
• Prevalence of child and adolescent psychiatric disorders in southeast Brazil.

  2004cited by this paper
• Internal and external validity of Attention-Deficit Hyperactivity Disorder in a population-based sample of adults

  2004cited by this paper
• Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain.

  2004cited by this paper
• Estrogen, but not testosterone, attenuates methamphetamine-evoked dopamine output from superfused striatal tissue of female and male mice.

  2003cited by this paper
• Family‐based and case‐control association studies of catechol‐O‐methyltransferase in attention deficit hyperactivity disorder suggest genetic sexual dimorphism

  2003cited by this paper
• Human catechol-O-methyltransferase down-regulation by estradiol.

  2003cited by this paper
• Estrogen, Anti‐Estrogen, and Gender

  2002cited by this paper
• Attention-deficit hyperactivity disorder: a study of association with both the dopamine transporter gene and the dopamine D4 receptor gene.

  2001cited by this paper
• Gender differences in dopaminergic function in striatum and nucleus accumbens.

  1999cited by this paper
• Characterization and implications of estrogenic down-regulation of human catechol-O-methyltransferase gene transcription.

  1999cited by this paper
• Immunocytochemical localization of the dopamine transporter in human brain

  1999cited by this paper
• The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10.

  1998cited by this paper
• Distribution of catechol‐O‐methyltransferase expression in human central nervous system

  1998cited by this paper
• Attention-deficit hyperactivity disorder: a category or a continuum? Genetic analysis of a large-scale twin study.

  1997cited by this paper
• The Strengths and Difficulties Questionnaire: a research note.

  1997cited by this paper
• Genetic influence on parent-reported attention-related problems in a Norwegian general population twin sample.

  1996cited by this paper
• Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme.

  1995cited by this paper
• Population genetic study of the human dopamine transporter gene (DAT1)

  1995cited by this paper
• [Affective disorders in the fourth edition of the classification of mental disorders prepared by the American Psychiatric Association -- diagnostic and statistical manual of mental disorders].

  1993cited by this paper
• The Dopamine Theory of Attention Deficit Hyperactivity Disorder (ADHD)

  1991cited by this paper
• Principles of Statistics

  1983cited by this paper

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  2022cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
• Population neuroscience: challenges and opportunities for psychiatric research in low- and middle-income countries

  2020cites this paper
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  2019cites this paper
• Shared genetic background between children and adults with attention deficit/hyperactivity disorder

  2019cites this paper
• A Neurodevelopmental Model of Combined Pyrethroid and Chronic Stress Exposure

  2019cites this paper
• Effects of Exercise on Cognitive Performance in Children and Adolescents with ADHD: Potential Mechanisms and Evidence-based Recommendations

  2019cites this paper
• Association analyses reveal gender-specific associations of DAT1 40-bp VNTR and -839C/T polymorphisms with obsessive–compulsive disorder and obsessive–compulsive symptoms

  2019cites this paper
• The dopamine transporter role in psychiatric phenotypes

  2018cites this paper
• Genetic association study of dyslexia and ADHD candidate genes in a Spanish cohort: Implications of comorbid samples

  2018cites this paper
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  2018cites this paper