Increasing membrane tension decreases miscibility temperatures; an experimental demonstration via micropipette aspiration.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Biophysical Journal

• Publication date

  2012-10-17

• Fields of study

  Materials Science, Medicine, Physics, Chemistry

• Identifiers
  DOI 10.1016/j.bpj.2012.08.061PMID 23083725PMCID PMC3475388
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Phase behavior of lipid bilayers under tension.

  2012influential reference
• Raft domains of variable properties and compositions in plasma membrane vesicles

  2011influential reference
• Lateral phase separation in tense membranes

  2011cited by this paper
• Measurement Error: Models, Methods, and Applications

  2010cited by this paper
• Minimal model of plasma membrane heterogeneity requires coupling cortical actin to criticality.

  2010cited by this paper
• Tuning lipid mixtures to induce or suppress domain formation across leaflets of unsupported asymmetric bilayers

  2008cited by this paper
• Critical fluctuations in plasma membrane vesicles.

  2008influential reference
• Elasticity, strength, and water permeability of bilayers that contain raft microdomain-forming lipids.

  2008cited by this paper
• Raft composition at physiological temperature and pH in the absence of detergents.

  2008cited by this paper
• Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles

  2007influential reference
• Lipid peroxides promote large rafts: effects of excitation of probes in fluorescence microscopy and electrochemical reactions during vesicle formation.

  2006cited by this paper
• Tension-induced morphological transition in mixed lipid bilayers.

  2005cited by this paper
• Seeing spots: complex phase behavior in simple membranes.

  2005cited by this paper
• Membrane tether formation from blebbing cells.

  1999cited by this paper
• Membrane Tension in Swelling and Shrinking Molluscan Neurons

  1998cited by this paper
• Mechanically stimulated cytoskeleton rearrangement and cortical contraction in human neutrophils.

  1995cited by this paper
• Entropy-driven tension and bending elasticity in condensed-fluid membranes.

  1990cited by this paper
• Thermoelasticity of large lecithin bilayer vesicles.

  1981cited by this paper

• Stretching drives Membrane Homogenization of Phase-Separated Supported Lipid Bilayers

  2026influential citation
• Electrodeformation of DMPC vesicle membranes near the main phase transition.

  2025cites this paper
• Thermal preconditioning of membrane stress to control the shapes of ultrathin crystals.

  2024cites this paper
• Methyl-β-cyclodextrin asymmetrically extracts phospholipid from bilayers, granting tunable control over differential stress in lipid vesicles

  2024cites this paper
• RNA: The Unsuspected Conductor in the Orchestra of Macromolecular Crowding

  2024cites this paper
• Sterol–lipids enable large-scale, liquid–liquid phase separation in bilayer membranes of only two components

  2024cites this paper
• Elastic and thermodynamic consequences of lipid membrane asymmetry.

  2023cites this paper
• Coupling Liquid Phases in 3D Condensates and 2D Membranes: Successes, Challenges, and Tools.

  2023cites this paper
• Systematic measurements of interleaflet friction in supported bilayers

  2022cites this paper
• Intelligent fluorescence image analysis of giant unilamellar vesicles using convolutional neural network

  2022cites this paper
• Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system

  2022cites this paper
• Methods to mechanically perturb and characterize GUV-based minimal cell models

  2022cites this paper
• Remodeling of yeast vacuole membrane lipidomes from the log (1-phase) to stationary stage (2-phases)

  2022cites this paper
• Fluid-Gel Coexistence in Lipid Membranes under Differential Stress.

  2022cites this paper
• Micropipette-based biomechanical nanotools on living cells

  2022cites this paper
• Switchable positioning of plate-like inclusions in lipid membranes: Elastically mediated interactions of planar colloids in 2D fluids

  2021cites this paper
• Structural and mechanical parameters of lipid bilayer membranes using a lattice refined self-consistent field theory.

  2021cites this paper
• Polymer-Lipid Hybrid Materials.

  2021cites this paper
• Intelligent Fluorescence Image Analysis of Giant Unilamellar Vesicles and Protein Liquid Phase Droplets by Whole Z-stack Analysis

  2021cites this paper
• Superelasticity of Plasma‐ and Synthetic Membranes Resulting from Coupling of Membrane Asymmetry, Curvature, and Lipid Sorting

  2021cites this paper
• Self-consistent field modeling of mesomorphic phase changes of monoolein and phospholipids in response to additives.

  2021cites this paper
• Phase separation in biological membranes: An overview with focus on experimental effects of illumination and osmotic pressure changes

  2021cites this paper
• EPA and DHA differentially modulate membrane elasticity in the presence of cholesterol

  2021cites this paper
• Principles and Applications of Biological Membrane Organization.

  2020cites this paper
• Imaging non-classical mechanical responses of lipid membranes using molecular rotors

  2020cites this paper
• Recent advancements to measure membrane mechanical and transport properties

  2020cites this paper
• Super-elasticity of plasma- and synthetic membranes by coupling of membrane asymmetry and liquid-liquid phase separation

  2020cites this paper
• Osmotic-Tension-Induced Membrane Lateral Organization.

  2020cites this paper
• Lipid Raft Phase Modulation by Membrane-Anchored Proteins with Inherent Phase Separation Properties

  2019cites this paper
• Complex Phase Behavior of GUVs Containing Different Sphingomyelins.

  2019cites this paper
• Advances in Micropipette Aspiration: Applications in Cell Biomechanics, Models, and Extended Studies.

  2019cites this paper
• Physical Plasma Membrane Perturbation Using Subcellular Optogenetics Drives Integrin-Activated Cell Migration.

  2019cites this paper
• Giant Vesicles and Their Use in Assays for Assessing Membrane Phase State, Curvature, Mechanics, and Electrical Properties.

  2019cites this paper
• Acute decrease in plasma membrane tension induces macropinocytosis via PLD2 activation

  2019cites this paper
• Observations of Membrane Domain Reorganization in Mechanically Compressed Artificial Cells

  2019cites this paper
• Annual Review of Biophysics Giant Vesicles and Their Use in Assays for Assessing Membrane Phase State , Curvature , Mechanics , and Electrical Properties

  2019cites this paper
• The plasma membrane as a mechanochemical transducer

  2019cites this paper
• Role of Nanoparticle Mechanical Properties in Cancer Drug Delivery.

  2019cites this paper
• An acute decrease in plasma membrane tension induces macropinocytosis via PLD2 activation

  2019cites this paper
• Plasma membrane tension regulates eisosome structure and function

  2019cites this paper
• Modulations of Lipid Membranes Caused by Antimicrobial Agents and Helix 0 of Endophilin

  2019cites this paper
• Visualizing Tension and Growth in Model Membranes Using Optical Dyes.

  2018cites this paper
• Liquid-liquid phase transition temperatures increase when lipid bilayers are supported on glass.

  2018cites this paper
• Modulation of phase separation at the micron scale and nanoscale in giant polymer/lipid hybrid unilamellar vesicles (GHUVs).

  2017cites this paper
• Hallmarks of Reversible Phase Separation in Living, Unperturbed Cell Membranes

  2017cites this paper
• The Effect of Solutes on the Temperature of Miscibility Transitions in Multicomponent Membranes.

  2017cites this paper
• Modulation of lipid membrane structural and mechanical properties by a peptidomimetic derived from reduced amide scaffold.

  2017cites this paper
• Systems biology of cellular membranes: a convergence with biophysics

  2017cites this paper
• Production of Isolated Giant Unilamellar Vesicles under High Salt Concentrations

  2017cites this paper
• Size and mobility of lipid domains tuned by geometrical constraints

  2017cites this paper
• Mixing Water, Transducing Energy, and Shaping Membranes: Autonomously Self-Regulating Giant Vesicles.

  2016cites this paper
• Stabilizing membrane domains antagonizes n-alcohol anesthesia

  2016cites this paper
• Shift in membrane miscibility transition temperature upon addition of short-chain alcohols.

  2016cites this paper
• Inquiry of Lipid Membranes Interacting with Functional Peptides and Polyphenol Drug Molecules

  2016cites this paper
• Stabilizing membrane domains antagonizes n-alcohol anesthesia

  2016cites this paper
• Membranes under shear stress: visualization of non-equilibrium domain patterns and domain fusion in a microfluidic device.

  2016cites this paper
• Specific adhesion of membranes simultaneously supports dual heterogeneities in lipids and proteins.

  2015cites this paper
• Effect of neurosteroids on a model lipid bilayer including cholesterol: An Atomic Force Microscopy study.

  2015cites this paper
• Transbilayer Colocalization of Lipid Domains Explained via Measurement of Strong Coupling Parameters.

  2015cites this paper
• Measuring the Effect of Tension on Lipid Membrane Viscosity

  2015cites this paper
• Live cell plasma membranes do not exhibit a miscibility phase transition over a wide range of temperatures.

  2015cites this paper
• Membrane adhesion and the formation of heterogeneities: biology, biophysics, and biotechnology.

  2015cites this paper
• GENESIS: a hybrid-parallel and multi-scale molecular dynamics simulator with enhanced sampling algorithms for biomolecular and cellular simulations

  2015cites this paper
• Measuring how lipid membranes respond to physical perturbations: How charge alters lipid miscibility, how shear disrupts interleaflet coupling, and how prebiotic compounds affect membrane stability

  2015cites this paper
• UNCORRECTED PROOF 1Q1 Effect of neurosteroids on a model lipid bilayer including cholesterol: An 2 Atomic Force Microscopy study

  2015cites this paper
• Electric Field Induced Deformations of Biomimetic Fluid Membranes

  2015cites this paper
• Oscillatory phase separation in giant lipid vesicles induced by transmembrane osmotic differentials

  2014influential citation
• Recent developments in the field of bending rigidity measurements on membranes.

  2014cites this paper
• Fluid domain patterns in free-standing membranes captured on a solid support.

  2014cites this paper
• THE IMPACT OF MEMBRANE TENSION ON PHASE SEPARATION AND SOLID DOMAIN PROPERTIES IN MODEL MULTICOMPONENT VESICLES

  2014cites this paper
• Three dimensional (temperature-tension-composition) phase map of mixed DOPC-DPPC vesicles: Two solid phases and a fluid phase coexist on three intersecting planes.

  2014cites this paper
• Surface tension effects on the phase transition of a DPPC bilayer with and without protein: a molecular dynamics simulation.

  2014cites this paper
• Phase transitions in supported lipid bilayers studied by AFM.

  2014cites this paper
• Large effect of membrane tension on the fluid–solid phase transitions of two-component phosphatidylcholine vesicles

  2013cites this paper
• Domain formation in cholesterol-phospholipid membranes exposed to adhesive surfaces or environments†

  2013cites this paper
• Minimal effect of lipid charge on membrane miscibility phase behavior in three ternary systems.

  2013cites this paper
• Coarsening dynamics of domains in lipid membranes.

  2012cites this paper
• Recent developments in the fi eld of bending rigidity measurements on membranes

  year unknowncites this paper