Stem cell source-dependent reconstitution of FOXP3+ T cells after pediatric SCT and the association with allo-reactive disease

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Bone Marrow Transplantation

• Publication date

  2013-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/bmt.2012.174PMID 23000652
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Graft-Versus-Host Disease

  2016cited by this paper
• CD3+/Tregs ratio in donor grafts is linked to acute graft-versus-host disease and immunologic recovery after allogeneic peripheral blood stem cell transplantation.

  2012cited by this paper
• Higher CD3+ and CD34+ cell doses in the graft increase the incidence of acute GVHD in children receiving BMT for thalassemia

  2012cited by this paper
• Critical role for programmed death 1 signaling and protein kinase B in augmented regulatory T-cell induction in cord blood.

  2011cited by this paper
• Interleukin-2 and regulatory T cells in graft-versus-host disease.

  2011cited by this paper
• Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation.

  2010cited by this paper
• Frequency of CD4(+)CD25(hi)FOXP3(+) regulatory T cells has diagnostic and prognostic value as a biomarker for acute graft-versus-host-disease.

  2010cited by this paper
• Increase in FOXP3+ regulatory T cells in GVHD skin biopsies is associated with lower disease severity and treatment response.

  2009cited by this paper
• Ex vivo expanded cord blood CD4 T lymphocytes exhibit a distinct expression profile of cytokine‐related genes from those of peripheral blood origin

  2009cited by this paper
• Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab

  2009cited by this paper
• The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

  2008cited by this paper
• Delayed immune reconstitution after cord blood transplantation is characterized by impaired thymopoiesis and late memory T-cell skewing.

  2007cited by this paper
• Immune reconstitution following hematopoietic stem-cell transplantation.

  2007cited by this paper
• Graft-versus-host disease

  2007cited by this paper
• A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta.

  2007cited by this paper
• T cell regeneration in pediatric allogeneic stem cell transplantation

  2007cited by this paper
• Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype.

  2007cited by this paper
• Immune reconstitution after unrelated cord blood transplantation.

  2007cited by this paper
• Advances in the understanding of acute graft‐versus‐host disease

  2007cited by this paper
• A Kinetic and Dynamic Analysis of Foxp3 Induced in T Cells by TGF-β1

  2007cited by this paper
• High donor FOXP3-positive regulatory T-cell (Treg) content is associated with a low risk of GVHD following HLA-matched allogeneic SCT.

  2006cited by this paper
• Graft-versus-host disease in the 21st century: new perspectives on an old problem.

  2006cited by this paper
• Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network.

  2006cited by this paper
• Reduced frequency of FOXP3+ CD4+CD25+ regulatory T cells in patients with chronic graft-versus-host disease.

  2005cited by this paper
• Cutting Edge: Self-Peptides Drive the Peripheral Expansion of CD4+CD25+ Regulatory T Cells 1

  2003cited by this paper
• Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

  2003cited by this paper
• CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantation

  2003cited by this paper
• Origin of regulatory T cells with known specificity for antigen

  2002cited by this paper
• The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethality.

  2002cited by this paper
• Donor-type CD4+CD25+ Regulatory T Cells Suppress Lethal Acute Graft-Versus-Host Disease after Allogeneic Bone Marrow Transplantation

  2002cited by this paper
• Delayed Apoptotic Cell Clearance and Lupus-like Autoimmunity in Mice Lacking the c-mer Membrane Tyrosine Kinase

  2002cited by this paper
• Molecular basis of HLA polymorphism: implications in clinical transplantation.

  2002cited by this paper
• Supporting Online Material

  2002cited by this paper
• CD4+CD25+ Immunoregulatory T Cells

  2002cited by this paper
• Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

  2001cited by this paper
• The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

  2001cited by this paper
• Evaluation of TruCount Absolute-Count Tubes for Determining CD4 and CD8 Cell Numbers in Human Immunodeficiency Virus-Positive Adults

  2000cited by this paper
• Mismatches of minor histocompatibility antigens between HLA-identical donors and recipients and the development of graft-versus-host disease after bone marrow transplantation.

  1996cited by this paper
• Idiopathic Pneumonia Syndrome after Bone Marrow Transplantation

  1993cited by this paper
• An acute pulmonary syndrome possibly representing acute graft-versus-host disease involving the lung interstitium.

  1991cited by this paper
• Cell cycle analysis of a cell proliferation-associated human nuclear antigen defined by the monoclonal antibody Ki-67.

  1984cited by this paper
• CLINICAL MANIFESTATIONS OF GRAFT‐VERSUS-HOST DISEASE IN HUMAN RECIPIENTS OF MARROW FROM HL‐A-MATCHED SIBLING DONOR,S

  1974cited by this paper

• Harmonized immune recovery monitoring after HCT: evidence and practical guidance from the Westhafen Intercontinental Group

  2025cites this paper
• Early reversal of the lymphocyte‐to‐monocyte ratio after allogeneic‐hematopoietic stem cell transplantation is associated with reduced relapse and improved prognosis

  2023cites this paper
• Rapid Reconstitution of Treg Subsets is Associated with Reduced Rates of Acute GvHD and Absence of Viremia after Cord Blood Transplantation in Children with Reduced-Intensity Conditioning utilizing Alemtuzumab

  2020influential citation
• Reconstitution of T Cell Subsets Following Allogeneic Hematopoietic Cell Transplantation

  2020influential citation
• Rapid reconstitution of regulatory T-cell subsets is associated with reduced rates of acute graft-versus-host disease and absence of viremia after cord blood transplantation in children with reduced-intensity conditioning using alemtuzumab.

  2020cites this paper
• Pre-transplantation thymic function is associated with the risk of acute graft versus host disease and cytomegalovirus viremia after allogeneic hematopoietic stem cell transplantation

  2018cites this paper
• Immune Reconstitution after Allogeneic Hematopoietic Cell Transplantation in Children.

  2016cites this paper