UGT1A1 polymorphism is associated with serum bilirubin concentrations in a randomized, controlled, fruit and vegetable feeding trial.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of NutriLife

• Publication date

  2007-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/JN/137.4.890PMID 17374650
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Association of SULT1A1 and UGT1A1 polymorphisms with breast cancer risk and phenotypes in Russian women

  2006cited by this paper
• Relevance of Meat Fat Content and Fruit and Vegetable Intake for the Oxidative Status of Pigs

  2006cited by this paper
• Study of the genetic determinants of UGT1A1 inducibility by phenobarbital in cultured human hepatocytes

  2006cited by this paper
• Serum bilirubin and colorectal cancer risk: a population‐based cohort study

  2006cited by this paper
• [Association of polymorphisms in SULT1A1 and UGT1A1 Genes with breast cancer risk and phenotypes in Russian women].

  2006cited by this paper
• In vivo investigation of changes in biomarkers of oxidative stress induced by plant food rich diets.

  2005cited by this paper
• Genetic polymorphism in the phenobarbital-responsive enhancer module of the UDP-glucuronosyltransferase 1A1 gene and irinotecan toxicity

  2005cited by this paper
• UGT1A1 polymorphisms are important determinants of dietary carcinogen detoxification in the liver

  2005cited by this paper
• A dietary pattern that lowers oxidative stress increases antibodies to oxidized LDL: results from a randomized controlled feeding study.

  2005cited by this paper
• Polymorphic variations in the expression of the chemical detoxifying UDP glucuronosyltransferases.

  2005cited by this paper
• The impact of glucuronidation on the bioactivation and DNA adduction of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in vivo.

  2005influential reference
• Cruciferae interact with the UGT1A1*28 polymorphism to determine serum bilirubin levels in humans.

  2005cited by this paper
• 8-Isoprostane F2alpha excretion is reduced in women by increased vegetable and fruit intake.

  2005cited by this paper
• Exploring hepatic hormone actions using a compilation of gene expression profiles

  2005cited by this paper
• [Induction of uridine 5'-diphosphate-glucuronosyltransferase gene expression by sulforaphane and its mechanism: experimental study in human colon cancel cells].

  2005cited by this paper
• Isoflavones modulate the glucuronidation of estradiol in human liver microsomes.

  2005cited by this paper
• Molecular Mechanism of Nrf2 Activation by Oxidative Stress

  2005cited by this paper
• Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells.

  2004cited by this paper
• The 6-a-day study: effects of fruit and vegetables on markers of oxidative stress and antioxidative defense in healthy nonsmokers.

  2004cited by this paper
• Correlation between the UDP-Glucuronosyltransferase (UGT1A1) TATAA Box Polymorphism and Carcinogen Detoxification Phenotype

  2004cited by this paper
• UGT1A1*28 polymorphism in ovarian cancer patients.

  2004cited by this paper
• Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 (UGT1A1) and risk of breast cancer

  2004cited by this paper
• The Functional UGT1A1 Promoter Polymorphism Decreases Endometrial Cancer Risk

  2004cited by this paper
• Cruciferous vegetable consumption alters the metabolism of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in humans.

  2004cited by this paper
• Serum bilirubin levels in the U.S. Population: Gender effect and inverse correlation with colorectal cancer

  2004cited by this paper
• Differential modulation of UDP-glucuronosyltransferase 1A1 (UGT1A1)-catalyzed estradiol-3-glucuronidation by the addition of UGT1A1 substrates and other compounds to human liver microsomes.

  2002cited by this paper
• Sex differences in drug metabolism: cytochrome P-450 and uridine diphosphate glucuronosyltransferase.

  2002cited by this paper
• HCC: What's the score

  2002cited by this paper
• Sulforaphane and its glutathione conjugate but not sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in cultured cells.

  2002cited by this paper
• Identification of a defect in the UGT1A1 gene promoter and its association with hyperbilirubinemia.

  2002cited by this paper
• Association of genetic polymorphisms in UGT1A1 with breast cancer and plasma hormone levels.

  2001cited by this paper
• Potent induction of phase 2 enzymes in human prostate cells by sulforaphane.

  2001cited by this paper
• Association of Genetic Polymorphisms in UGT 1 A 1 with Breast Cancer and Plasma Hormone Levels 1

  2001cited by this paper
• Wheat bran and soy protein feeding do not alter urinary excretion of the isoflavan equol in premenopausal women.

  2001cited by this paper
• Induction of UDP-Glucuronosyltransferase UGT1A1 by the Flavonoid Chrysin in Caco-2 Cells—Potential Role in Carcinogen Bioinactivation

  2001cited by this paper
• Serum bilirubin and 10-year mortality risk in a Belgian population

  2001cited by this paper
• Modulation of human glutathione S-transferases by botanically defined vegetable diets.

  2000cited by this paper
• Bilirubin and bile acids may modulate their own metabolism via regulating uridine diphosphate‐glucuronosyltransferase expression in the rat

  2000cited by this paper
• Genetic polymorphisms in uridine diphospho-glucuronosyltransferase 1A1 and association with breast cancer among African Americans.

  2000cited by this paper
• Association of human liver bilirubin UDP-glucuronyltransferase activity with a polymorphism in the promoter region of the UGT1A1 gene.

  2000cited by this paper
• Effects of watercress consumption on urinary metabolites of nicotine in smokers.

  1999cited by this paper
• UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations.

  1999cited by this paper
• Molecular genetic basis of Gilbert’s syndrome

  1999cited by this paper
• A urinary biomarker for uptake of dietary isothiocyanates in humans.

  1998cited by this paper
• Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism?

  1998cited by this paper
• Soy feeding induces phase II enzymes in rat tissues.

  1996cited by this paper
• Effects of consumption of brussels sprouts on plasma and urinary glutathione S-transferase class-alpha and -pi in humans.

  1995cited by this paper
• Effects of consumption of Brussels sprouts on intestinal and lymphocytic glutathione S-transferases in humans.

  1995cited by this paper
• The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome.

  1995cited by this paper
• Effects of consumption of Brussels sprouts on plasma and urinary glutathione S-transferase class-α and -π in humans

  1995cited by this paper
• Investigation of the substrate specificity of a cloned expressed human bilirubin UDP-glucuronosyltransferase: UDP-sugar specificity and involvement in steroid and xenobiotic glucuronidation.

  1994cited by this paper
• Effects of anticarcinogenic monoterpenes on phase II hepatic metabolizing enzymes.

  1993cited by this paper
• Effects of soya bean flakes and liquorice root extract on enzyme induction and toxicity in B6C3F1 mice.

  1993cited by this paper
• New developments in glucuronidation research: Report of a workshop on “Glucuronidation, its role in health and disease”

  1992cited by this paper
• Dietary modification of drug-metabolizing enzyme activities: dose-response effect of flavonoids.

  1992cited by this paper
• Drug glucuronidation in humans.

  1991cited by this paper
• The increase in urinary excretion of 6 beta-hydroxycortisol as a marker of human hepatic cytochrome P450IIIA induction.

  1989cited by this paper
• Effect of estrogen/progestin potency on clinical chemistry measures. The Lipid Research Clinics Program Prevalence Study.

  1986cited by this paper
• Effect of brussels sprouts and cabbage on drug conjugation

  1984cited by this paper

• Diet Item Details: Reporting Checklist for Feeding Studies Measuring the Dietary Metabolome (DID-METAB Checklist)—Explanation and Elaboration Report on the Development of the Checklist by the DID-METAB Delphi Working Group

  2025cites this paper
• The beneficial effect of sulforaphane on platelet responsiveness during caloric load: a single-intake, double-blind, placebo-controlled, crossover trial in healthy participants

  2023cites this paper
• Consumption of baby kale increased cytochrome P450 1A2 (CYP1A2) activity and influenced bilirubin metabolism in a randomized clinical trial

  2020cites this paper
• The Effects of Cruciferous Vegetable‐Enriched Diets on Drug Metabolism: A Systematic Review and Meta‐Analysis of Dietary Intervention Trials in Humans

  2020cites this paper
• Future prospects for dissecting inter-individual variability in the absorption, distribution and elimination of plant bioactives of relevance for cardiometabolic endpoints

  2019cites this paper
• Dose adjustment of irinotecan based on UGT1A1 polymorphisms in patients with colorectal cancer

  2018cites this paper
• The role of metabolism (and the microbiome) in defining the clinical efficacy of dietary flavonoids

  2016cites this paper
• Association of flavonoid-rich foods and statins in the management of hypercholesterolemia: a dangerous or helpful combination?

  2015cites this paper
• Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application

  2015cites this paper
• Effect of apple, baobab, red-chicory, and pear extracts on cellular energy expenditure and morphology of a Caco-2 cells using transepithelial electrical resistance (TEER) and scanning electron microscopy (SEM)

  2015cites this paper
• Association Between Flavonoid-Rich Fruit and Vegetable Consumption and Total Serum Bilirubin

  2015cites this paper
• Cruciferous vegetables have variable effects on biomarkers of systemic inflammation in a randomized controlled trial in healthy young adults.

  2014cites this paper
• A Dietary Pattern Characterized by a High Consumption of Vegetables and Fruits is related to lower Concentrations of Serum Bilirubin in Japanese women

  2014influential citation
• How does Nutrigenetics Influence Long-Term Health?

  2013cites this paper
• Metabolomic profiling of urine: response to a randomised, controlled feeding study of select fruits and vegetables, and application to an observational study

  2013cites this paper
• Mechanisms underlying food-drug interactions: inhibition of intestinal metabolism and transport.

  2012cites this paper
• UGT1A6 and UGT2B15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized, Controlled Diet of Select Fruits and Vegetables

  2011cites this paper
• UGT 1 A 6 and UGT 2 B 15 Polymorphisms and Acetaminophen Conjugation in Response to a Randomized , Controlled Diet of Select Fruits and Vegetables

  2011influential citation
• Bilirubin, cardiovascular diseases and cancer: epidemiological perspectives

  2010cites this paper
• Genetic polymorphism in metabolism and host defense enzymes: Implications for human health risk assessment

  2010cites this paper
• Dietary and Demographic Correlates of Serum β-Glucuronidase Activity

  2010cites this paper
• The clinical application of UGT1A1 pharmacogenetic testing: Gene-environment interactions

  2010cites this paper
• DNA Damage and Repair: Fruit and Vegetable Effects in a Feeding Trial

  2010cites this paper
• Cruciferous Vegetable Intake and Cancer Prevention: Role of Nutrigenetics

  2009cites this paper
• Citrus fruit intake is associated with lower serum bilirubin concentration among women with the UGT1A1*28 polymorphism.

  2009influential citation
• Human gut bacterial communities are altered by addition of cruciferous vegetables to a controlled fruit- and vegetable-free diet.

  2009cites this paper
• Cruciferous Vegetable Feeding Alters UGT1A1 Activity: Diet- and Genotype-Dependent Changes in Serum Bilirubin in a Controlled Feeding Trial

  2009influential citation
• Antioxidant status of bilirubin and uric acid in patients diagnosed with Plasmodium falciparum malaria in Douala.

  2008cites this paper
• Serum β-Glucuronidase Activity in Response to Fruit and Vegetable Supplementation: A Controlled Feeding Study

  2008cites this paper
• Urinary 3-(3,5-dihydroxyphenyl)-1-propanoic acid, an alkylresorcinol metabolite, is a potential biomarker of whole-grain intake in a U.S. population.

  2008cites this paper