Capsid and Infectivity in Virus Detection

The spectacular achievements and elegance of viral RNA analyses have somewhat obscured the importance of the capsid in transmission of viruses via food and water. The capsid’s essential roles are protection of the RNA when the virion is outside the host cell and initiation of infection when the virion contacts a receptor on an appropriate host cell. Capsids of environmentally transmitted viruses are phenomenally durable. Fortuitous properties of the capsid include antigenicity, isoelectric point(s), sometimes hemagglutination, and perhaps others. These can potentially be used to characterize capsid changes that cause or accompany loss of viral infectivity and may be valuable in distinguishing native from inactivated virus when molecular detection methods are used.

• Publication year

  2009

• Venue

  Food and Environmnetal Virology

• Publication date

  2009-11-13

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1007/s12560-009-9020-yPMID 20234879PMCID 2837222
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Norovirus and histo-blood group antigens.

  2011cited by this paper
• Isolation and infectivity of potential foodborne viral pathogens by immunomagnetic capture.

  2009cited by this paper
• Visualizing the dynamics of viral replication in living cells via Tat peptide delivery of nuclease-resistant molecular beacons

  2008cited by this paper
• Detection of Hepatitis A Virus by Using a Combined Cell Culture-Molecular Beacon Assay

  2008cited by this paper
• Application of PCR-Based Methods To Assess the Infectivity of Enteric Viruses in Environmental Samples

  2008influential reference
• Norovirus recognizes histo-blood group antigens on gastrointestinal cells of clams, mussels, and oysters: a possible mechanism of bioaccumulation.

  2007cited by this paper
• Detection of Murine Norovirus 1 by Using Plaque Assay, Transfection Assay, and Real-Time Reverse Transcription-PCR before and after Heat Exposure

  2007influential reference
• Degradation of the Poliovirus 1 genome by chlorine dioxide

  2006cited by this paper
• Norwalk Virus–specific Binding to Oyster Digestive Tissues

  2006cited by this paper
• Detection of Norovirus Capsid Protein in Authentic Standards and in Stool Extracts by Matrix-Assisted Laser Desorption Ionization and Nanospray Mass Spectrometry

  2006cited by this paper
• Porcine gastric mucin binds to recombinant norovirus particles and competitively inhibits their binding to histo‐blood group antigens and Caco‐2 cells

  2005cited by this paper
• Effect of acid pH, salts, and temperature on the infectivity and physical integrity of enteroviruses

  2005influential reference
• Norovirus and Histo-Blood Group Antigens: Demonstration of a Wide Spectrum of Strain Specificities and Classification of Two Major Binding Groups among Multiple Binding Patterns

  2005cited by this paper
• The Structure of the Poliovirus 135S Cell Entry Intermediate at 10-Angstrom Resolution Reveals the Location of an Externalized Polypeptide That Binds to Membranes

  2005cited by this paper
• Inactivation of Caliciviruses

  2004cited by this paper
• Use of reverse transcription and PCR to discriminate between infectious and non-infectious hepatitis A virus.

  2004cited by this paper
• Reduction of Norwalk Virus, Poliovirus 1, and Bacteriophage MS2 by Ozone Disinfection of Water

  2003cited by this paper
• Enteroviruses: Polioviruses, Coxsackieviruses, Echoviruses and Newer Enteroviruses

  2003cited by this paper
• Infectivity of RNA from Inactivated Poliovirus

  2003cited by this paper
• Norwalk Virus-Like Particle Hemagglutination by Binding to H Histo-Blood Group Antigens

  2003influential reference
• Noroviruses bind to human ABO, Lewis, and secretor histo-blood group antigens: identification of 4 distinct strain-specific patterns.

  2003cited by this paper
• Capsid Functions of Inactivated Human Picornaviruses and Feline Calicivirus

  2003cited by this paper
• Hepatitis E virus

  2003cited by this paper
• Norwalk virus binds to histo-blood group antigens present on gastroduodenal epithelial cells of secretor individuals

  2002cited by this paper
• Pretreatment to avoid positive RT-PCR results with inactivated viruses.

  2002cited by this paper
• Picornaviridae : the viruses and their replication

  2001cited by this paper
• PRINCIPLES OF VIRUS STRUCTURE

  1999cited by this paper
• Identification of a surface glycoprotein on African green monkey kidney cells as a receptor for hepatitis A virus.

  1996cited by this paper
• Picornaviridae: The viruses and their replication

  1996cited by this paper
• [Hepatitis A virus].

  1995cited by this paper
• Antiviral effects of bacteria isolated from manure

  1995cited by this paper
• Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding

  1990cited by this paper
• Trypsin sensitivity of the Sabin strain of type 1 poliovirus: cleavage sites in virions and related particles

  1985cited by this paper
• A broad-spectrum enzyme-linked immunosorbent assay for the detection of human enteric viruses.

  1984cited by this paper
• Evidence that microorganisms cause inactivation of viruses in activated sludge

  1982cited by this paper
• Antiviral Effectiveness of Grape Juice.

  1979cited by this paper
• Antiviral effect of commercial juices and beverages

  1978cited by this paper
• Antiviral effect of apple beverages

  1978cited by this paper
• Virus inactivation by grapes and wines

  1976cited by this paper
• Gamma radiation inactivation of coxsackievirus B-2.

  1973cited by this paper
• Characterization of type 1 poliovirus by electrophoretic analysis.

  1971cited by this paper
• Inactivation of thirty viruses by gamma radiation.

  1971cited by this paper

• Potential of essential oils in control of pathogenic plant viruses

  2025cites this paper
• Aspects of biosecurity of pig feed production (review)

  2025cites this paper
• Virus communities rather than bacterial communities contribute more on nutrient pool in polluted aquatic environment.

  2024cites this paper
• Determination of airborne influenza virus and coronavirus infectivity using capsid integrity polymerase chain reaction.

  2024cites this paper
• Plate-Based High-Throughput Fluorescence Assay for Assessing Enveloped Virus Integrity

  2024cites this paper
• Wavelength-specific inactivation mechanisms and efficacies of germicidal UVC for airborne human coronavirus.

  2024cites this paper
• Evaluating storage conditions and enhancement strategies on viral biomarker recovery for WBE applications.

  2024cites this paper
• Effects of Essential Oils and Hydrolates on the Infectivity of Murine Norovirus

  2023cites this paper
• Latin American Plants against Microorganisms

  2023influential citation
• Development and efficacy assessment of hand sanitizers and polylactic acid films incorporating caffeic acid and vanillin for enhanced antiviral properties against HCoV-229E

  2023cites this paper
• Antiviral edible coatings and films: A strategy to ensure food safety

  2023cites this paper
• Effectiveness of TRIzol in Inactivating Animal Pathogens

  2023cites this paper
• Plant and insect virus-like particles: Emerging nanoparticles for agricultural pest management.

  2023cites this paper
• Inactivation of Human Norovirus GII.4 and Vibrio parahaemolyticus in the Sea Squirt (Halocynthia roretzi) by Floating Electrode-Dielectric Barrier Discharge Plasma

  2023cites this paper
• Can food matrices be considered as a potential carrier for COVID-19?

  2022cites this paper
• Detection of suid herpesvirus 1 infectivity in pigs by propidium monoazide-qPCR

  2022cites this paper
• A review on molecular detection techniques of white spot syndrome virus: Perspectives of problems and solutions in shrimp farming

  2022cites this paper
• Atypical Viral Infections in Gastroenterology

  2022cites this paper
• Archival influenza virus genomes from Europe reveal genomic variability during the 1918 pandemic

  2022cites this paper
• Impact of Theaflavins-Enriched Tea Leaf Extract TY-1 against Surrogate Viruses of Human Norovirus: In Vitro Virucidal Study

  2022cites this paper
• UV inactivation of sewage isolated human adenovirus.

  2022cites this paper
• Study of the chemical and in vitro cytotoxic activities of essential oils (EOs) of two plants from the Ivorian flora (Lippia multiflora, Zingiber officinale) and their antiviral activities against non-enveloped viruses

  2022cites this paper
• Evaluation of heat treatment for inactivation of norovirus genogroup II in foods

  2022cites this paper
• New food safety challenges of viral contamination from a global perspective: Conventional, emerging, and novel methods of viral control.

  2022cites this paper
• SARS-CoV-2 Subgenomic RNA Kinetics in Longitudinal Clinical Samples

  2021cites this paper
• Recent Update on UV Disinfection to Fulfill the Disinfection Credit Value for Enteric Viruses in Water.

  2021cites this paper
• Antiviral Potential of Plants against Noroviruses

  2021cites this paper
• Archival influenza virus genomes from Europe reveal genomic and phenotypic variability during the 1918 pandemic

  2021cites this paper
• Exploitation of polyphenols and proteins using nanoencapsulation for anti-viral and brain boosting properties – Evoking a synergistic strategy to combat COVID-19 pandemic

  2021cites this paper
• Water and Pathogenic Viruses Inactivation—Food Engineering Perspectives

  2020cites this paper
• Antiviral Effects of Plant-Derived Essential Oils and Their Components: An Updated Review

  2020cites this paper
• A review of strategies to impact swine feed biosecurity

  2020cites this paper
• Airborne spread of infectious SARS-CoV-2: Moving forward using lessons from SARS-CoV and MERS-CoV

  2020cites this paper
• Magnetic Microdevices for MRI-Based Detection of SARS-CoV-2 Viruses

  2020cites this paper
• Tracing goes viral: viruses that introduce expression of fluorescent proteins in chemically-specific neurons.

  2020cites this paper
• Natural bioactive substances for the control of food-borne viruses and contaminants in food

  2020cites this paper
• Plausible fast & economic detection of SARS-CoV infection using paper-based isoelectric focusing: a hypothesis

  2020cites this paper
• Magnetic Microdevices for MRI-Based Detection of SARS-CoV-2 Viruses

  2020cites this paper
• Therapeutic potentials of Scavenger receptor CD36 mediated innate immune responses against infectious and non-infectious diseases.

  2019cites this paper
• Norovirus: The Burden of the Unknown.

  2018cites this paper
• Performance of pre‐RT‐qPCR treatments to discriminate infectious human rotaviruses and noroviruses from heat‐inactivated viruses: applications of PMA/PMAxx, benzonase and RNase

  2018cites this paper
• Antimicrobial Activity of Essential Oils

  2018cites this paper
• Étude des propriétés de surface du bactériophage MS2 et du norovirus murin au cours de différents traitements d’inactivation

  2017cites this paper
• Mechanism of Anti-rotavirus Synergistic Activity by Epigallocatechin Gallate and a Proanthocyanidin-Containing Nutraceutical

  2017cites this paper
• Natural Virucidal Compounds in Foods

  2016influential citation
• Strain-Specific Virolysis Patterns of Human Noroviruses in Response to Alcohols

  2016cites this paper
• Arc discharge-mediated disassembly of viral particles in water.

  2016cites this paper
• Evaluation of propidium monoazide and long-amplicon qPCR as an infectivity assay for coliphage.

  2016cites this paper
• Therapeutic potential of flavonoids and their mechanism of action against microbial and viral infections—A review

  2015cites this paper
• Propidium monoazide reverse transcriptase PCR and RT-qPCR for detecting infectious enterovirus and norovirus.

  2015cites this paper
• Culture-Independent Evaluation of Nonenveloped-Virus Infectivity Reduced by Free-Chlorine Disinfection

  2015cites this paper
• Natural persistence of food- and waterborne viruses

  2014cites this paper
• Virus entériques transmissibles par voie alimentaire : détection, typage, pouvoir infectieux et nouvelles technologies

  2014influential citation
• Noroviruses on surfaces : Detection, transfer and inactivation

  2014cites this paper
• Mechanisms of Antiviral Action of Plant Antimicrobials against Murine Norovirus

  2014influential citation
• Antiviral efficacy and mechanisms of action of oregano essential oil and its primary component carvacrol against murine norovirus

  2014cites this paper
• A critical review of methods for detecting human noroviruses and predicting their infectivity

  2013cites this paper
• Ciliate-adenovirus interactions in experimental co-cultures of Euplotes octocarinatus and in wastewater environment.

  2013cites this paper
• WATERBORNE VIRAL PATHOGENS: DETECTION, CONTROL AND MONITORING OF WATER QUALITY FOR HUMAN CONSUMPTION

  2013cites this paper
• Virus quantitation by transmission electron microscopy, TCID₅₀, and the role of timing virus harvesting: a case study of three animal viruses.

  2013cites this paper
• Chemical Disinfectants for Inactivation of Human Norovirus Surrogates

  2013cites this paper
• Discrimination of infectious hepatitis A virus and rotavirus by combining dyes and surfactants with RT-qPCR

  2013cites this paper
• Virus inactivation on hard surfaces or in suspension by chemical disinfectants: systematic review and meta-analysis of norovirus surrogates.

  2013cites this paper
• An introduction to food- and waterborne viral disease

  2013cites this paper
• Removal of MS2, Qβ and GA bacteriophages during drinking water treatment at pilot scale.

  2012cites this paper
• Analytical methods for the detection of viruses in food by example of CCL-3 bioagents

  2012cites this paper
• Mass Spectrometric and Molecular Analyses of Biological Agents In Environmental Compartments

  2012influential citation
• Dan Li, Mieke Uyttendaele 2

  2012cites this paper
• Effect of pH on Anti-Rotavirus Activity by Comestible Juices and Proanthocyanidins in a Cell-Free Assay System

  2012cites this paper
• Reducing the effects of environmental inhibition in quantitative real-time PCR detection of adenovirus and norovirus in recreational seawaters.

  2012cites this paper
• Measurement of the virolysis of human GII.4 norovirus in response to disinfectants and sanitisers.

  2011cites this paper
• In vitro influence of D/L-lactic acid, sodium chloride and sodium nitrite on the infectivity of feline calicivirus and of ECHO virus as potential surrogates for foodborne viruses.

  2011cites this paper
• Comparison of chlorine and peroxyacetic-based disinfectant to inactivate Feline calicivirus, Murine norovirus and Hepatitis A virus on lettuce.

  2011cites this paper
• Adsorption characteristics of an enteric virus-binding protein to norovirus, rotavirus and poliovirus

  2011cites this paper