LASER server: ancestry tracing with genotypes or sequence reads

D. Taliun,S. Chothani,S. Schönherr,L. Forer,M. Boehnke,G. Abecasis,Chaolong Wang

Published 2017 in Bioinform.

ABSTRACT

Summary: To enable direct comparison of ancestry background in different studies, we developed LASER to estimate individual ancestry by placing either sezquenced or genotyped samples in a common ancestry space, regardless of the sequencing strategy or genotyping array used to characterize each sample. Here we describe the LASER server to facilitate application of the method to a wide range of genetic studies. The server provides genetic ancestry estimation for different geographic regions and user‐friendly interactive visualization of the results. Availability and Implementation: The LASER server is freely accessible at http://laser.sph.umich.edu/ Contact: dtaliun@umich.edu or wangcl@gis.a‐star.edu.sg Supplementary information: Supplementary data are available at Bioinformatics online.

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