Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of NutriLife

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1093/JN/132.1.115PMID 11773517
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nicotinamide and diabetes prevention.

  2009cited by this paper
• Niacin deficiency decreases bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats.

  2002cited by this paper
• Niacin Deficiency in Rats Increases the Severity of Ethylnitrosourea-Induced Anemia and Leukopenia 1

  2000cited by this paper
• Immunological determination and size characterization of poly(ADP-ribose) synthesized in vitro and in vivo.

  1999cited by this paper
• Effect of niacin on atherosclerotic cardiovascular disease.

  1998cited by this paper
• Cellular responses to DNA damage in the absence of Poly(ADP-ribose) polymerase.

  1998cited by this paper
• The secondary leukemias: challenges and research directions.

  1996cited by this paper
• DNA damage and repair in tumour and non-tumour tissues of mice induced by nicotinamide.

  1996cited by this paper
• Nicotinamide and other benzamide analogs as agents for overcoming hypoxic cell radiation resistance in tumours. A review.

  1995cited by this paper
• Dual function for poly(ADP-ribose) synthesis in response to DNA strand breakage.

  1994cited by this paper
• Secondary malignancies following cancer chemotherapy.

  1994cited by this paper
• Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis.

  1993cited by this paper
• Diethylnitrosamine administration in vivo increases hepatic poly(ADP-ribose) levels in rats: results of a modified technique for poly(ADP-ribose) measurement.

  1993cited by this paper
• AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet.

  1993influential reference
• Molecular and biochemical features of poly (ADP-ribose) metabolism

  1993cited by this paper
• Specific inhibitors of poly(ADP-ribose) synthetase and mono(ADP-ribosyl)transferase.

  1992cited by this paper
• Prevention or delay of Type 1 (insulin-dependent) diabetes mellitus in children using nicotinamide

  1991cited by this paper
• Use of niacin as a drug.

  1991cited by this paper
• Alkylating agents.

  1990cited by this paper
• Inhibition of Lipolysis by Agents Acting Via Adenylate Cyclase in Fat Cells from Infants and Adults

  1989cited by this paper
• Effect of a modified, well-tolerated niacin regimen on serum total cholesterol, high density lipoprotein cholesterol and the cholesterol to high density lipoprotein ratio.

  1989cited by this paper
• Tumor radiosensitization by nicotinamide: a result of improved perfusion and oxygenation.

  1989cited by this paper
• Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo.

  1989cited by this paper
• The influence of niacin and nicotinamide on in vivo carcinogenesis.

  1986cited by this paper
• Comparison of O6-alkylguanine-DNA alkyltransferase activity based on cellular DNA content in human, rat and mouse tissues.

  1986cited by this paper
• Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin.

  1986cited by this paper

• Beyond Pellagra—Research Models and Strategies Addressing the Enduring Clinical Relevance of NAD Deficiency in Aging and Disease

  2023cites this paper
• NAD+ Acts as a Protective Factor in Cellular Stress Response to DNA Alkylating Agents

  2023cites this paper
• The Effect of Zinc and Niacin Powder Addition on some Physiological and Production Performance of Turkey

  2023cites this paper
• NAD+ Precursors and Intestinal Inflammation: Therapeutic Insights Involving Gut Microbiota

  2023cites this paper
• Fueling genome maintenance: On the versatile roles of NAD+ in preserving DNA integrity

  2022cites this paper
• Role of Nicotinamide Adenine Dinucleotide and Related Precursors as Therapeutic Targets for Age-Related Degenerative Diseases: Rationale, Biochemistry, Pharmacokinetics, and Outcomes

  2019cites this paper
• Effect of dietary niacin supplementation on performance, total tract nutrient retention, carcass yield and meat lipid profile of growing turkeys

  2019cites this paper
• Effect of Dietary Niacin Supplementation on Growth Performance, Nutrient Digestibility, Hematology, and Lipoprotein Concentrations of Young Turkeys, Meleagris gallopavo

  2019cites this paper
• Effect of pharmacological doses of niacin on testicular structure and function in normal and diabetic rats

  2018cites this paper
• The NAD+ precursor nicotinic acid improves genomic integrity in human peripheral blood mononuclear cells after X-irradiation.

  2017cites this paper
• The Effect of Conjugated Linoleic Acids (CLA) Supplementation on the Activity of Enzymes Participating in the Formation of Arachidonic Acid in Liver Microsomes of Rats—Probable Mechanism of CLA Anticancer Activity

  2015cites this paper
• Nicotinic acid supplementation in the context of alcoholic liver injury: friend or foe?

  2014cites this paper
• Niacin requirements for genomic stability.

  2012cites this paper
• Niacin status and genomic instability in bone marrow cells; mechanisms favoring the progression of leukemogenesis.

  2012cites this paper
• Raising cellular NAD+ levels in human cells by nicotinic acid supplementation : biological consequences related to PARP-1 mediated reactions

  2012cites this paper
• Dietary nicotinic acid supplementation improves hepatic zinc uptake and offers hepatoprotection against oxidative damage

  2011cites this paper
• Ex vivo supplementation with nicotinic acid enhances cellular poly(ADP-ribosyl)ation and improves cell viability in human peripheral blood mononuclear cells.

  2010cites this paper
• Chapter 18 Cellular Aging and Death

  2010cites this paper
• Functional analysis of mitochondrial sirtuins in C. elegans and mammalian cells

  2010cites this paper
• Vitamin B3, the nicotinamide adenine dinucleotides and aging.

  2010cites this paper
• Niacin Status Impacts Chromatin Structure 1 – 3

  2009cites this paper
• Niacin status impacts chromatin structure.

  2009cites this paper
• Niacin status, NAD distribution and ADP-ribose metabolism.

  2009cites this paper
• Niacin status and treatment-related leukemogenesis

  2009cites this paper
• Strategies to Potentiate the Cellular Poly(ADP-ribosyl)ation Response to DNA Damage

  2009cites this paper
• NAD+ and Vitamin B3: From Metabolism to Therapies

  2008influential citation
• Co-enzyme Q10, riboflavin and niacin supplementation on alteration of DNA repair enzyme and DNA methylation in breast cancer patients undergoing tamoxifen therapy.

  2008cites this paper
• Niacin Supplementation Decreases the Incidence of Alkylation-Induced Nonlymphocytic Leukemia in Long-Evans Rats

  2008cites this paper
• Water maze performance in young male Long-Evans rats is inversely affected by dietary intakes of niacin and may be linked to levels of the NAD+ metabolite cADPR.

  2007cites this paper
• Pharmacological targeting of IDO-mediated tolerance for treating autoimmune disease.

  2007cites this paper
• Vitamin-Dependent Modifications of Chromatin: Epigenetic Events and Genomic Stability

  2007cites this paper
• Niacin Deficiency Alters p53 Expression and Impairs Etoposide-Induced Cell Cycle Arrest and Apoptosis in Rat Bone Marrow Cells

  2007cites this paper
• Role of Poly-ADP-Ribosylation in Cancer Development

  2006cites this paper
• Poly(ADP-ribosyl)ation in relation to cancer and autoimmune disease.

  2005cites this paper
• Poly-ADP-ribosylation in health and disease

  2005cites this paper
• Parp‐1 deficiency implicated in colon and liver tumorigenesis induced by azoxymethane

  2003cites this paper
• Nonisotopic Methods for Determination of Poly(ADP‐Ribose) Levels and Detection of Poly(ADP‐Ribose) Polymerase

  2003cites this paper
• Niacin and Carcinogenesis

  2003cites this paper
• Chronic DNA Damage and Niacin Deficiency Enhance Cell Injury and Cause Unusual Interactions in NAD and Poly(ADP-Ribose) Metabolism in Rat Bone Marrow

  2003cites this paper
• Niacin deficiency increases spontaneous and etoposide-induced chromosomal instability in rat bone marrow cells in vivo.

  2002cites this paper