Independent cytotoxic and inflammatory responses to zinc oxide nanoparticles in human monocytes and macrophages

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Nanotoxicology

• Publication date

  2012-10-12

• Fields of study

  Medicine, Materials Science, Environmental Science

• Identifiers
  DOI 10.3109/17435390.2011.620718PMID 22087559
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Sunset Yellow and Allura Red modulate Bcl2 and COX2 expression levels and confer oxidative stress-mediated renal and hepatic toxicity in male rats

  2018influential reference
• Silver nanoparticles: evaluation of DNA damage, toxicity and functional impairment in human mesenchymal stem cells.

  2011cited by this paper
• Temporal and mechanistic tracking of cellular uptake dynamics with novel surface fluorophore-bound nanodiamonds.

  2011cited by this paper
• ZnO particulate matter requires cell contact for toxicity in human colon cancer cells.

  2010cited by this paper
• Lack of significant dermal penetration of titanium dioxide from sunscreen formulations containing nano- and submicron-size TiO2 particles.

  2010cited by this paper
• Toxicity of zinc oxide (ZnO) nanoparticles on human bronchial epithelial cells (BEAS-2B) is accentuated by oxidative stress.

  2010cited by this paper
• Skin absorption studies of octyl-methoxycinnamate loaded poly(D,L-lactide) nanoparticles: Estimation of the UV filter distribution and release behaviour in skin layers

  2010cited by this paper
• Role of the dissolved zinc ion and reactive oxygen species in cytotoxicity of ZnO nanoparticles.

  2010cited by this paper
• Small amounts of zinc from zinc oxide particles in sunscreens applied outdoors are absorbed through human skin.

  2010cited by this paper
• Zinc oxide nanoparticles induce photocatalytic cell death in human head and neck squamous cell carcinoma cell lines in vitro.

  2010cited by this paper
• Permeation pathway of macromolecules and nanospheres through skin.

  2010cited by this paper
• Better safe than sorry: Understanding the toxicological properties of inorganic nanoparticles manufactured for biomedical applications.

  2010cited by this paper
• Nanoparticles: a closer look at their dermal effects.

  2010cited by this paper
• Exposure to ZnO nanoparticles induces oxidative stress and cytotoxicity in human colon carcinoma cells.

  2010cited by this paper
• Effects of surface chemistry on cytotoxicity, genotoxicity, and the generation of reactive oxygen species induced by ZnO nanoparticles.

  2010cited by this paper
• Uptake and inflammatory effects of nanoparticles in a human vascular endothelial cell line.

  2009cited by this paper
• Selective cytotoxic effect of ZnO nanoparticles on glioma cells

  2009cited by this paper
• The Influences of Cell Type and ZnO Nanoparticle Size on Immune Cell Cytotoxicity and Cytokine Induction

  2009cited by this paper
• Skin immune sentinels in health and disease

  2009cited by this paper
• Toxicity and penetration of TiO2 nanoparticles in hairless mice and porcine skin after subchronic dermal exposure.

  2009cited by this paper
• Physicochemical factors that affect metal and metal oxide nanoparticle passage across epithelial barriers.

  2009cited by this paper
• Nanotoxicology: nanoparticles reconstruct lipids.

  2009cited by this paper
• Nanocarriers’ entry into the cell: relevance to drug delivery

  2009cited by this paper
• Differential plasma protein binding to metal oxide nanoparticles

  2009cited by this paper
• Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

  2008cited by this paper
• Exposure to titanium dioxide and other metallic oxide nanoparticles induces cytotoxicity on human neural cells and fibroblasts

  2008cited by this paper
• Molecular and Cellular Mechanisms of Photocarcinogenesis †

  2007cited by this paper
• Assessing toxicity of fine and nanoparticles: comparing in vitro measurements to in vivo pulmonary toxicity profiles.

  2007cited by this paper
• Immune response modifiers – mode of action

  2006cited by this paper
• The role of apoptosis (programmed cell death) in haemopoiesis and the immune system.

  1993cited by this paper
• IL-8 gene expression and production in human peripheral blood lymphocyte subsets.

  1991cited by this paper
• Temporal changes of lysosome and phagosome pH during phagolysosome formation in macrophages: studies by fluorescence spectroscopy

  1981cited by this paper
• Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1)

  1980cited by this paper
• Immune responses to environmental antigens that act on the skin: the role of lymphokines in contact dermatitis.

  1977cited by this paper

• A comprehensive study on the biodegradability, biocompatibility, and antibacterial properties of additively manufactured PLA-ZnO nanocomposites

  2025cites this paper
• Cytotoxic effect of zinc oxide phytonanoparticles and Bonellia macrocarpa (Cav.) B. Stahl & Källersjö extract on breast cancer cell lines

  2025cites this paper
• Zinc oxide nanoparticles exacerbate skin epithelial cell damage by upregulating pro-inflammatory cytokines and exosome secretion in M1 macrophages following UVB irradiation-induced skin injury

  2024cites this paper
• Silver nanoparticles forensic uses and toxicity on vital organs and different body systems

  2024cites this paper
• A multi-technique analytical approach to support (eco)toxicological investigation of zinc oxide nanoparticles.

  2024cites this paper
• Toxicological Aspects, Safety Assessment, and Green Toxicology of Silver Nanoparticles (AgNPs)—Critical Review: State of the Art

  2023cites this paper
• Zinc associated nanomaterials and their intervention in emerging respiratory viruses: Journey to the field of biomedicine and biomaterials

  2022cites this paper
• Biodegradable Alginate Films with ZnO Nanoparticles and Citronella Essential Oil—A Novel Antimicrobial Structure

  2021cites this paper
• Modulation of Innate Immune Toxicity by Silver Nanoparticle Exposure and the Preventive Effects of Pterostilbene

  2021cites this paper
• Fundamental Toxicological Sciences

  2021cites this paper
• Zinc nanostructures: Toxicity, safety, and regulation in agroecosystems

  2021cites this paper
• Cytotoxicity of Novel Polymeric Gel Matrix Triple Antibiotic Paste—an In Vitro Study

  2020cites this paper
• Facile Use of ZnO Nanopowders to Protect Old Manual Paper Documents

  2020cites this paper
• Risks of Nanotechnology to Human Life

  2019cites this paper
• Long-term exposure to low doses of fresh and aged zinc oxide nanoparticles causes cell malignant progression enhanced by a tyrosine phosphatase SHP2 gain-of-function mutation

  2019cites this paper
• Realistic Exposure Study Assists Risk Assessments of ZnO Nanoparticle Sunscreens and Allays Safety Concerns.

  2019cites this paper
• Zirconia Nanoparticles-Induced Toxic Effects in Osteoblast-Like 3T3-E1 Cells

  2018cites this paper
• Immunotoxicology of Metals

  2018cites this paper
• Enhanced biostability and cellular uptake of zinc oxide nanocrystals shielded with a phospholipid bilayer

  2017cites this paper
• Zinc oxide nanoparticles induce toxic responses in human neuroblastoma SHSY5Y cells in a size-dependent manner

  2017cites this paper
• In vitro toxicological effects of zinc containing nanoparticles with different physico-chemical properties.

  2017influential citation
• The toxicology of ion-shedding zinc oxide nanoparticles

  2016cites this paper
• ZnO nanoparticles and organic chemical UV-filters are equally well tolerated by human immune cells

  2016influential citation
• Nanoparticles and direct immunosuppression

  2016cites this paper
• Potential risks and benefits of nanotechnology: perceptions of risk in sunscreens

  2016cites this paper
• Value of phagocyte function screening for immunotoxicity of nanoparticles in vivo

  2015cites this paper
• Investigating the immunomodulatory nature of zinc oxide nanoparticles at sub-cytotoxic levels in vitro and after intranasal instillation in vivo

  2015cites this paper
• Engineered metal based nanoparticles and innate immunity

  2015cites this paper
• Quantum dot agglomerates in biological media and their characterization by asymmetrical flow field-flow fractionation.

  2015cites this paper
• Biological reactivity of zinc oxide nanoparticles with mammalian test systems: an overview.

  2015cites this paper
• Characterizing the inhibitory action of zinc oxide nanoparticles on allergic-type mast cell activation.

  2015cites this paper
• Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4.

  2014cites this paper
• Applicability of rat precision-cut lung slices in evaluating nanomaterial cytotoxicity, apoptosis, oxidative stress, and inflammation.

  2014cites this paper
• Pulmonary toxicity of nanomaterials: a critical comparison of published in vitro assays and in vivo inhalation or instillation studies.

  2014cites this paper
• Comparative effects of zinc oxide nanoparticles and dissolved zinc on zebrafish embryos and eleuthero-embryos: importance of zinc ions.

  2014cites this paper
• Critical experimental parameters related to the cytotoxicity of zinc oxide nanoparticles

  2014cites this paper
• Investigating the interactions between nonoparticles and UV-irradiated HaCaT keratinocytes

  2014cites this paper
• Comparison of UVA-induced ROS and sunscreen nanoparticle-generated ROS in human immune cells

  2014cites this paper
• Immunotoxicity of zinc oxide nanoparticles with different size and electrostatic charge

  2014cites this paper
• Reducing ZnO nanoparticle cytotoxicity by surface modification.

  2014cites this paper
• The effect of nanoparticles on the function of immune cells of the skin

  2014influential citation
• The effect of formulation on the penetration of coated and uncoated zinc oxide nanoparticles into the viable epidermis of human skin in vivo.

  2013cites this paper
• Safety of engineered nanomaterials and OH&S issues for commercial-scale production

  2013cites this paper
• Effect of Surface‐Modified Gold Nanorods on the Inflammatory Cytokine Response in Macrophage Cells

  2013cites this paper
• Single cell array based assay for in vitro genotoxicity study of nanomaterials.

  2013cites this paper
• Relating cytotoxicity, zinc ions, and reactive oxygen in ZnO nanoparticle-exposed human immune cells.

  2013cites this paper
• Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle

  2013cites this paper
• Quantification of ZnO nanoparticle uptake, distribution, and dissolution within individual human macrophages.

  2013cites this paper
• Surface coatings of ZnO nanoparticles mitigate differentially a host of transcriptional, protein and signalling responses in primary human olfactory cells

  2013cites this paper
• Zinc oxide nanoparticle removal from wounded human skin.

  2013cites this paper
• Investigating the immunotoxicology of silver nanoparticles in vitro

  2012influential citation
• Formation of zinc-containing nanoparticles from Zn²⁺ ions in cell culture media: implications for the nanotoxicology of ZnO.

  2012cites this paper