Decreased insulin secretion in islets from rats fed a low protein diet is associated with a reduced PKAalpha expression.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Journal of NutriLife

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/JN/134.1.63PMID 14704294
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Obesity and Diabetes

  2010cited by this paper
• Decreased cholinergic stimulation of insulin secretion by islets from rats fed a low protein diet is associated with reduced protein kinase calpha expression.

  2003cited by this paper
• Obesity and diabetes.

  2003cited by this paper
• Pharmacological Agents That Directly Modulate Insulin Secretion

  2003cited by this paper
• Prolactin-Signal Transduction in Neonatal Rat Pancreatic Islets and Interaction with the Insulin-Signaling Pathway

  2003cited by this paper
• Beta-cell protein kinases and the dynamics of the insulin response to glucose.

  2002cited by this paper
• Blockade of IRS1 in isolated rat pancreatic islets improves glucose‐induced insulin secretion

  2002cited by this paper
• Molecular mechanisms controlling the localisation of protein kinase A

  2002cited by this paper
• A protein-restricted diet during pregnancy alters in vitro insulin secretion from islets of fetal Wistar rats.

  2001cited by this paper
• Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism.

  2001cited by this paper
• Evidence for multiple signaling pathways in the regulation of gene expression by amino acids in human cell lines.

  2000cited by this paper
• Adaptive changes in insulin secretion by islets from neonatal rats raised on a high-carbohydrate formula.

  2000cited by this paper
• Synergism of protein kinase A, protein kinase C, and myosin light-chain kinase in the secretory cascade of the pancreatic beta-cell.

  2000cited by this paper
• Printed in U.S.A. Copyright © 2001 by The Endocrine Society Glucagon-Like Peptide-1 Causes Pancreatic Duodenal Homeobox-1 Protein Translocation from the Cytoplasm to the Nucleus of Pancreatic �-Cells by a Cyclic

  2000cited by this paper
• The cyclic AMP-protein kinase A pathway restrains islet phospholipase A(2) activation.

  2000cited by this paper
• Amino acid limitation regulates gene expression

  1999cited by this paper
• Normalization of array hybridization experiments in differential gene expression analysis.

  1999cited by this paper
• Amino acid regulation of gene expression.

  1999cited by this paper
• Protein deficiency and nutritional recovery modulate insulin secretion and the early steps of insulin action in rats.

  1998cited by this paper
• Protein kinases, protein phosphorylation, and the regulation of insulin secretion from pancreatic beta-cells.

  1998cited by this paper
• Neurotransmitters and their receptors in the islets of langerhans of the pancreas

  1998cited by this paper
• Moderate dietary protein and energy restriction modulate cAMP-dependent protein kinase activity in rat liver.

  1998cited by this paper
• Synergistic activation of RLD-1 by agents triggering PKA and PKC dependent signalling.

  1998cited by this paper
• Protein kinase A and protein kinase C synergistically activate the Raf-1 kinase/mitogen-activated protein kinase cascade in neonatal rat cardiomyocytes.

  1997cited by this paper
• Multiple Exocytotic Pathways in Pancreatic β Cells

  1997cited by this paper
• Glucose-induced insulin secretion is impaired and insulin-induced phosphorylation of the insulin receptor and insulin receptor substrate-1 are increased in protein-deficient rats.

  1997cited by this paper
• Albumin standards and the measurement of serum albumin with bromcresol green. 1971.

  1997cited by this paper
• Very low protein diets induce a rapid decrease in hepatic cAMP-dependent protein kinase followed by a lower increase in adenylyl cyclase activity in rats.

  1996cited by this paper
• Role of thyroid hormones in early postnatal development of skeletal muscle and its implications for undernutrition

  1996cited by this paper
• Ionic mechanisms involved in the regulation of insulin secretion by muscarinic agonists

  1995cited by this paper
• Changes in insulin action and insulin secretion in the rat after dietary restriction early in life: influence of food restriction versus low-protein food restriction.

  1995cited by this paper
• Synergistic interaction of glucose and neurohumoral agonists to stimulate islet phosphoinositide hydrolysis.

  1995cited by this paper
• [GLP-1 and the control of insulin secretion].

  1994cited by this paper
• AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet.

  1993cited by this paper
• Metabolic changes during early starvation in rats fed a low-protein diet in the postweaning growth period.

  1992cited by this paper
• Glucose utilization and insulin action in adult rats submitted to prolonged food restriction.

  1992cited by this paper
• Persistent reduction of pancreatic Beta-cell mass after a limited period of protein-energy malnutrition in the young rat

  1992cited by this paper
• Protein kinase C activation by 12-O-tetradecanoylphorbol 13-acetate modulates messenger ribonucleic acid levels for two of the regulatory subunits of 3',5'-cyclic adenosine monophosphate-dependent protein kinases (RII beta and RI alpha) via multiple and distinct mechanisms.

  1992cited by this paper
• Increased insulin action in the rat after protein malnutrition early in life

  1991cited by this paper
• Protein kinase C activation selectively increases mRNA levels for one of the regulatory subunits (RI alpha) of cAMP-dependent protein kinases in HT-29 cells.

  1990cited by this paper
• Dynamics of the distribution of cyclic AMP-dependent protein kinase in living cells.

  1990cited by this paper
• Muscarinic receptor subtypes in rat pancreatic islets: binding and functional studies.

  1990cited by this paper
• Glucocorticoid receptors and glucocorticoid effects in rat Sertoli cells.

  1989cited by this paper
• Modifications of gastric inhibitory polypeptide (GIP) secretion in man by a high-fat diet

  1988cited by this paper
• Differential regulation of messenger ribonucleic acids for specific subunits of cyclic adenosine 3',5'-monophosphate (cAMP)-dependent protein kinase by cAMP in rat Sertoli cells.

  1988cited by this paper
• Repercussions of chronic protein-calorie malnutrition on glucose homeostasis in the rat

  1987cited by this paper
• Persistent Impairment of Insulin Secretory Response to Glucose in Adult Rats After Limited Period of Protein-Calorie Malnutrition Early in Life

  1987cited by this paper
• Purification and characterization of hormone-regulated isoforms of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovaries.

  1985cited by this paper
• Effect of forskolin on islet cyclic AMP, insulin secretion, blood glucose and intravenous glucose tolerance in rats

  1984cited by this paper
• Failure to secrete immunoreactive insulin by rats fed a low protein diet.

  1983cited by this paper
• Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat.

  1982cited by this paper
• A method for the simultaneous measurement of insulin release and B cell membrane potential in single mouse islets of langerhans

  1981cited by this paper
• Phosphorylation-dephosphorylation of enzymes.

  1979cited by this paper
• The effects of protein-energy malnutrition on blood glucose homeostasis.

  1978cited by this paper
• Glucose tolerance and insulin release in malnourished rats.

  1976cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Biochemical characteristics of different forms of protein-energy malnutrition in rats.

  1973cited by this paper

• Type 5 Diabetes- The Rejuvenated Spirit from a Ghost of the Past

  2025cites this paper
• Undernutrition-Associated Diabetes Mellitus: Pathophysiology of a Global Problem.

  2025cites this paper
• Association between protein undernutrition and diabetes: Molecular implications in the reduction of insulin secretion

  2023cites this paper
• Low-arginine and low-protein diets induce hepatic lipid accumulation through different mechanisms in growing rats

  2020cites this paper
• Protein malnutrition prevents heat conservation induced by amino acid infusion during general anesthesia in rats.

  2019cites this paper
• Modulation of growth hormone receptor-insulin-like growth factor 1 axis by dietary protein in young ruminants

  2019cites this paper
• Reduced glucose‐induced insulin secretion in low‐protein‐fed rats is associated with altered pancreatic islets redox status

  2018cites this paper
• Nutritional recovery from a low-protein diet during pregnancy does not restore the kinetics of insulin secretion and Ca2+ or alterations in the cAMP/PKA and PLC/PKC pathways in islets from adult rats.

  2018cites this paper
• INVOLVIMENT OF THE PARASYMPATHETIC NERVOUS SYSTEM ON GLYCEMIC CONTROL AND PANCREATIC ISLETS FUNCTION IN MALNOURISHED MICE SUBMITTED TO THE HIGH-FAT DIET

  2017cites this paper
• Protein malnutrition after weaning disrupts peripheral clock and daily insulin secretion in mice.

  2017cites this paper
• Severe childhood malnutrition

  2017cites this paper
• Ghrelin doesn't limit insulin release in pregnant rats fed low protein diet.

  2017cites this paper
• Protein Quality in the First Thousand Days of Life

  2016cites this paper
• A low-protein diet during pregnancy prevents modifications in intercellular communication proteins in rat islets

  2015cites this paper
• Low-protein diet disrupts the crosstalk between the PKA and PKC signaling pathways in isolated pancreatic islets.

  2015cites this paper
• A low-protein diet combined with low-dose endotoxin leads to changes in glucose homeostasis in weanling rats.

  2015cites this paper
• Taurine supplementation increases KATP channel protein content, improving Ca2+ handling and insulin secretion in islets from malnourished mice fed on a high-fat diet

  2014cites this paper
• Reduced insulin secretion and glucose intolerance are involved in the fasting susceptibility of common vampire bats.

  2013cites this paper
• Impaired muscarinic type 3 (M3) receptor/PKC and PKA pathways in islets from MSG-obese rats

  2013cites this paper
• Assessment of Protein Adequacy in Developing Countries: Quality Matters

  2013cites this paper
• Increased Leptin Response and Inhibition of Apoptosis in Thymocytes of Young Rats Offspring from Protein Deprived Dams during Lactation

  2013cites this paper
• Assessment of protein adequacy in developing countries: quality matters

  2012cites this paper
• Differential activations of PKC/PKA related to microvasculopathy in diabetic GK rats.

  2012cites this paper
• Taurine supplementation restores glucose and carbachol-induced insulin secretion in islets from low-protein diet rats: involvement of Ach-M3R, Synt 1 and SNAP-25 proteins.

  2012cites this paper
• Protein restriction in early life is associated with changes in insulin sensitivity and pancreatic β-cell function during pregnancy

  2012cites this paper
• Decreased insulin secretion in islets from protein malnourished rats is associated with impaired glutamate dehydrogenase function: effect of leucine supplementation.

  2012cites this paper
• Mechanisms of insulin secretion in malnutrition: modulation by amino acids in rodent models

  2011cites this paper
• Lower expression of PKAα impairs insulin secretion in islets isolated from low-density lipoprotein receptor (LDLR(-/-)) knockout mice.

  2011cites this paper
• Impaired glucose tolerance in healthy men with low body weight

  2011cites this paper
• Avaliação da hemopoese e da resposta imune inata mediada por macrófagos em camundongos submetidos à recuperação nutricional após desnutrição protéica

  2010cites this paper
• Reduced insulin secretion in protein malnourished mice is associated with multiple changes in the beta-cell stimulus-secretion coupling.

  2010cites this paper
• Augmentation of insulin secretion by leucine supplementation in malnourished rats: possible involvement of the phosphatidylinositol 3-phosphate kinase/mammalian target protein of rapamycin pathway.

  2010cites this paper
• Leucine Supplementation Augments Insulin Secretion in Pancreatic Islets of Malnourished Mice

  2010cites this paper
• Genes and Nutrition

  2010cites this paper
• Insulin release, peripheral insulin resistance and muscle function in protein malnutrition: a role of tricarboxylic acid cycle anaplerosis

  2009cites this paper
• Nutrient modulation of insulin secretion.

  2009cites this paper
• Soybean diet improves insulin secretion through activation of cAMP/PKA pathway in rats.

  2008cites this paper
• Downregulated FKBP12.6 expression and upregulated endothelin signaling contribute to elevated diastolic calcium and arrhythmogenesis in rat cardiomyopathy produced by l-thyroxin.

  2008cites this paper
• RetractedDecreased FKBP12.6 expression and enhanced endothelin receptor signaling associated with arrhymogenesis in myocardial infarction rats

  2008cites this paper
• Impaired insulin secretion and decreased expression of the nutritionally responsive ribosomal kinase protein S6K-1 in pancreatic islets from malnourished rats.

  2008cites this paper
• Increased L-CPT-1 activity and altered gene expression in pancreatic islets of malnourished adult rats: a possible relationship between elevated free fatty acid levels and impaired insulin secretion.

  2008cites this paper
• Nutrigenomics, beta-cell function and type 2 diabetes.

  2007cites this paper
• Role of the autonomic nervous system in the development of hyperinsulinemia by high-carbohydrate formula feeding to neonatal rats.

  2007cites this paper
• Nutrigenomics, β-Cell Function and Type 2 Diabetes

  2007cites this paper
• arteries from aged OLETF rats, a model of Type 2 diabetes Imbalance between endothelium-derived relaxing and contracting factors in mesenteric

  2007cites this paper
• Low-protein diets reduce PKAalpha expression in islets from pregnant rats.

  2005cites this paper
• Low-Protein Diets Reduce PKAα Expression in Islets from Pregnant Rats

  2005cites this paper
• Vasopressin increases urea permeability in the initial IMCD from diabetic rats.

  2005cites this paper
• Diabetes-related changes in cAMP-dependent protein kinase activity and decrease in relaxation response in rat mesenteric artery.

  2004cites this paper