High Prevalence of Spirochetosis in Cholera Patients, Bangladesh

The microbes that accompany the etiologic agent of cholera, Vibrio cholerae, are only now being defined. In this study, spirochetes from the genus Brachyspira were identified at high titers in more than one third of cholera patients in Bangladesh. Spirochetosis should now be tracked in the setting of cholera outbreaks.

• Publication year

  2009

• Venue

  Emerging Infectious Diseases

• Publication date

  2009-04-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.3201/eid1504.081214PMID 19331734PMCID 2671413
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• Spirochetosis should be tracked in the setting of cholera outbreaks.

  Confidence 0.93

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewq (76h6bfydm6) review
• Brachyspira spirochetes were detected at high titers in more than one third of cholera patients in Bangladesh.

  Confidence 0.98

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewq (76h6bfydm6) review

• bangladesh

  location, setting

  The geographic location where the cholera patient samples were studied.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewq (76h6bfydm6) review
• brachyspira

  microorganism, genus

  A genus of spirochete bacteria mentioned as the organisms detected in patient samples.

  Aliases: Brachyspira spirochetes

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewq (76h6bfydm6) review
• cholera outbreaks

  event, epidemiologic setting

  Clusters of cholera cases in which additional microbial findings may be monitored.

  Aliases: cholera outbreak

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewq (76h6bfydm6) review
• cholera patients

  patient group, cohort

  People diagnosed with cholera and used as the patient group in the Bangladesh setting.

  Aliases: patients with cholera

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewq (76h6bfydm6) review
• high titers

  measurement, quantity

  A high measured abundance level of the detected spirochetes in the patient samples.

  Aliases: high titer

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewq (76h6bfydm6) review
• spirochetosis

  condition, infection

  The presence or infection of spirochetes in a host, treated here as a condition to monitor.

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewq (76h6bfydm6) review

• Complexity of rice-water stool from patients with Vibrio cholerae plays a role in the transmission of infectious diarrhea

  2007cited by this paper
• Getting serious about cholera.

  2006cited by this paper
• Intestinal spirochetosis and chronic watery diarrhea: Clinical and histological response to treatment and long‐term follow up

  2006cited by this paper
• Intestinal spirochetosis.

  2004cited by this paper
• Prevalence, risk factors and molecular epidemiology of Brachyspira pilosicoli in humans on the island of Bali, Indonesia.

  2004cited by this paper
• Intestinal spirochetosis.

  2004cited by this paper
• Clinical Significance of Human Intestinal Spirochetosis—A Morphologic Approach

  2003cited by this paper
• PCR detection of Brachyspira aalborgi and Brachyspira pilosicoli in human faeces.

  2001cited by this paper
• Comparative pathology and pathogenesis of naturally acquired and experimentally induced colonic spirochetosis

  2001cited by this paper
• Prevalence of Toxin Types and Colonization Factors in Enterotoxigenic Escherichia coli Isolated during a 2-Year Period from Diarrheal Patients in Bangladesh

  2000cited by this paper
• Brachyspira aalborgi Infection Diagnosed by Culture and 16S Ribosomal DNA Sequencing Using Human Colonic Biopsy Specimens

  2000cited by this paper
• Evaluation of day-old specific pathogen-free chicks as an experimental model for pathogenicity testing of intestinal spirochaete species.

  1998cited by this paper
• Experimental infection of newly weaned pigs with human and porcine strains of Serpulina pilosicoli

  1996cited by this paper
• Pathogenicity of human and porcine intestinal spirochetes in one-day-old specific-pathogen-free chicks: an animal model of intestinal spirochetosis

  1995cited by this paper
• Vibrio cholerae and cholera: molecular to global perspectives

  1995cited by this paper
• Vibrio cholerae and Cholera

  1994cited by this paper
• Vibrio cholerae and cholera : molecular to global perspectives

  1994cited by this paper
• Unusual in vitro formation of cyst-like structures associated with human intestinal spirochaetosis

  1989cited by this paper

• Exposed Proteomes of Brachyspira pilosicoli responsible for the overall decline in poultry and pig’s meat production

  2020cites this paper
• Identification of Widespread Antibiotic Exposure in Patients With Cholera Correlates With Clinically Relevant Microbiota Changes

  2019cites this paper
• The Spirochete Brachyspira pilosicoli, Enteric Pathogen of Animals and Humans

  2017cites this paper
• Brachyspira and its role in avian intestinal spirochaetosis.

  2014cites this paper
• Important Zoonotic Di eases : s Pre ention & Control

  2014cites this paper
• The pathogenic intestinal spirochaete Brachyspira pilosicoli forms a diverse recombinant species demonstrating some local clustering of related strains and potential for zoonotic spread

  2013cites this paper
• Multiple locus variable number tandem repeat analysis (MLVA) of the pathogenic intestinal spirochaete Brachyspira pilosicoli.

  2013cites this paper
• Exposure to norepinephrine enhances Brachyspira pilosicoli growth, attraction to mucin and attachment to Caco-2 cells.

  2011cites this paper
• The Complete Genome Sequence of the Pathogenic Intestinal Spirochete Brachyspira pilosicoli and Comparison with Other Brachyspira Genomes

  2010cites this paper
• The Intestinal Spirochete Brachyspira pilosicoli Attaches to Cultured Caco-2 Cells and Induces Pathological Changes

  2009cites this paper
• Spirochaetes as intestinal pathogens: Lessons from a Brachyspira genome

  2009cites this paper