Modulation of endoplasmic reticulum (ER) stress-induced autophagy by C/EBP homologous protein (CHOP) and inositol-requiring enzyme 1α (IRE1α) in human colon cancer cells.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Biochemical and Biophysical Research Communications - BBRC

• Publication date

  2014-03-07

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.bbrc.2014.02.054PMID 24565834
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• XBP1 mRNA Splicing Triggers an Autophagic Response in Endothelial Cells through BECLIN-1 Transcriptional Activation*

  2012cited by this paper
• BAX inhibitor‐1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response

  2011cited by this paper
• Gadd34 induces autophagy through the suppression of the mTOR pathway during starvation.

  2011cited by this paper
• The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

  2008cited by this paper
• A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

  2008cited by this paper
• XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease.

  2008cited by this paper
• Autophagy fights disease through cellular self-digestion

  2008cited by this paper
• ER stress (PERK/eIF2α phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation

  2007cited by this paper
• Signal integration in the endoplasmic reticulum unfolded protein response

  2007cited by this paper
• Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

  2007cited by this paper
• A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

  2007cited by this paper
• Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.

  2007cited by this paper
• Protein turnover via autophagy: implications for metabolism.

  2007cited by this paper
• Autophagy Is Activated for Cell Survival after Endoplasmic ReticulumStress

  2006cited by this paper
• Inhibition of Macroautophagy Triggers Apoptosis

  2005cited by this paper
• Subversion of Cellular Autophagosomal Machinery by RNA Viruses

  2005cited by this paper
• CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum.

  2004cited by this paper
• IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

  2002cited by this paper
• XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor.

  2001cited by this paper
• Perk is essential for translational regulation and cell survival during the unfolded protein response.

  2000cited by this paper
• Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

  2000cited by this paper
• LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

  2000cited by this paper
• ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.

  2000cited by this paper
• Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells.

  1998cited by this paper

• The Role of C/EBP‐Homologous Protein in Idiopathic Inflammatory Myopathies

  2025cites this paper
• Integrated stress response plasticity governs normal cell adaptation to chronic stress via the PP2A-TFE3-ATF4 pathway

  2024cites this paper
• Integrated stress response plasticity governs normal cell adaptation to chronic stress via the PP2A-TFE3-ATF4 pathway

  2024influential citation
• Aqueous extract of pulp of Maqui-Berry (Aristotelia chilensis) induces apoptosis in human endometrial carcinoma Ishikawa cells via mitochondrial and endoplasmic reticulum stress pathways

  2024cites this paper
• DDIT3 deficiency accelerates bone remodeling during bone healing by enhancing osteoblast and osteoclast differentiation through ULK1-mediated autophagy.

  2024cites this paper
• Ammodaucus leucotrichus Coss. & Dur. Attenuates acrylamide-induced hepatic injury through enhancing autophagy and inhibiting endoplasmic reticulum stress and apoptotic signaling

  2024cites this paper
• The clinical significance of circulating glucose-regulated protein 78, Caspase-3, and C/EBP homologous protein levels in patients with heart failure

  2023cites this paper
• Intricate subcellular journey of nanoparticles to the enigmatic domains of endoplasmic reticulum

  2023cites this paper
• Dual targeting agent Thiotert inhibits the progression of glioblastoma by inducing ER stress-dependent autophagy.

  2023cites this paper
• Ultraviolet Light, Unfolded Protein Response and Autophagy †

  2023cites this paper
• Toxic Effects of Gemcitabine and Paclitaxel Combination: Chemotherapy Drugs Exposure in Zebrafish

  2023influential citation
• Evidence against a contribution of the CCAAT-enhancer binding protein homologous protein (CHOP) in mediating neurotoxicity in rTg4510 mice

  2022cites this paper
• Intestinal Disorder in Zebrafish Larvae (Danio rerio): The Protective Action of N-Palmitoylethanolamide-oxazoline

  2022cites this paper
• Tri-2-Hydroxyarachidonein Induces Cytocidal Autophagy in Pancreatic Ductal Adenocarcinoma Cancer Cell Models

  2022cites this paper
• Sulforaphane is Synergistic with CB‐5083 and Inhibits Colony Formation of CB‐5083‐Resistant HCT116 Cells

  2022cites this paper
• GRP78 in lung cancer

  2021cites this paper
• Dehydrodiisoeugenol inhibits colorectal cancer growth by endoplasmic reticulum stress-induced autophagic pathways

  2020cites this paper
• Role of the mitochondrial calcium uniporter in Mg2+-free-induced epileptic hippocampal neuronal apoptosis

  2020cites this paper
• FAM134B Attenuates Seizure-Induced Apoptosis and Endoplasmic Reticulum Stress in Hippocampal Neurons by Promoting Autophagy

  2020cites this paper
• Targeting necroptosis in anticancer therapy: mechanisms and modulators

  2020cites this paper
• Inhibition of endoplasmic reticulum stress-induced autophagy promotes the killing effect of X-rays on sarcoma in mice.

  2019cites this paper
• Sourcing the immune system to induce immunogenic cell death in Kras-colorectal cancer cells

  2019cites this paper
• The Inflammatory Bowel Disease Drug Azathioprine Induces Autophagy via mTORC1 and the Unfolded Protein Response Sensor PERK.

  2019cites this paper
• The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress

  2019cites this paper
• Ethanol-Mediated Stress Promotes Autophagic Survival and Aggressiveness of Colon Cancer Cells via Activation of Nrf2/HO-1 Pathway

  2019cites this paper
• Hidden biochemical action of Ethanol on colon carcinoma cell models

  2019cites this paper
• CTCF inhibits endoplasmic reticulum stress and apoptosis in cardiomyocytes by upregulating RYR2 via inhibiting S100A1.

  2019cites this paper
• The C/EBP Homologous Protein (CHOP) Transcription Factor Functions in Endoplasmic Reticulum Stress-Induced Apoptosis and Microbial Infection

  2019cites this paper
• Interactions Between Autophagy and the Unfolded Protein Response: Implications for Inflammatory Bowel Disease.

  2019cites this paper
• TREM-1 Inhibition Restores Impaired Autophagy Activity and Reduces Colitis in Mice

  2018cites this paper
• Developmental toxicity induced by PM2.5 through endoplasmic reticulum stress and autophagy pathway in zebrafish embryos.

  2018cites this paper
• Combined inhibition of autophagy and Nrf2 signaling augments bortezomib-induced apoptosis by increasing ROS production and ER stress in pancreatic cancer cells

  2018cites this paper
• Nonlinear relationship between ER Ca2+ depletion versus induction of the unfolded protein response, autophagy inhibition, and cell death.

  2018cites this paper
• Radix Ophiopogonis polysaccharide extracts alleviate MPP+-induced PC-12 cell injury through inhibition of Notch signaling pathway.

  2018cites this paper
• Quercetin ameliorates HFD-induced NAFLD by promoting hepatic VLDL assembly and lipophagy via the IRE1a/XBP1s pathway.

  2018cites this paper
• ER stress‐mediated autophagic cell death induction through methylated &bgr;‐cyclodextrins‐threaded acid‐labile polyrotaxanes

  2018cites this paper
• Inhibition of the mitochondrial calcium uniporter inhibits Aβ-induced apoptosis by reducing reactive oxygen species-mediated endoplasmic reticulum stress in cultured microglia.

  2017cites this paper
• Role of the unfolded protein response in determining the fate of tumor cells and the promise of multi-targeted therapies

  2017cites this paper
• Transcription Factor C/EBP Homologous Protein in Health and Diseases

  2017cites this paper
• Endoplasmic Reticulum Stress Promotes Autophagy and Apoptosis and Reduces Chemotherapy Resistance in Mutant p53 Lung Cancer Cells

  2017cites this paper
• Inhibiting autophagy with chloroquine enhances the anti-tumor effect of high-LET carbon ions via ER stress-related apoptosis

  2017cites this paper
• UC Office of the President Recent Work Title Lithocholic acid induces endoplasmic reticulum stress , autophagy and mitochondrial dysfunction in human prostate cancer cells

  2016cites this paper
• Comprehensive Proteomic Study of the Antiproliferative Activity of a Polyphenol-Enriched Rosemary Extract on Colon Cancer Cells Using Nanoliquid Chromatography-Orbitrap MS/MS.

  2016cites this paper
• The reverse-mode NCX1 activity inhibitor KB-R7943 promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux

  2016cites this paper
• Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation

  2016cites this paper
• Lithocholic acid induces endoplasmic reticulum stress, autophagy and mitochondrial dysfunction in human prostate cancer cells

  2016cites this paper
• Different Roles of CHOP and JNK in Mediating Radiation-Induced Autophagy and Apoptosis in Breast Cancer Cells

  2016cites this paper
• Simultaneous inhibition of the ubiquitin-proteasome system and autophagy enhances apoptosis induced by ER stress aggravators in human pancreatic cancer cells

  2016cites this paper
• Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapy.

  2015cites this paper
• Interplay between unfolded protein response and autophagy promotes tumor drug resistance

  2015cites this paper
• Endoplasmic reticulum stress and oxidative stress are involved in ZnO nanoparticle-induced hepatotoxicity.

  2015influential citation
• Synergistic antitumor effects of radiation and proteasome inhibitor treatment in pancreatic cancer through the induction of autophagy and the downregulation of TRAF6.

  2015cites this paper
• Role of endoplasmic reticulum stress and autophagy as interlinking pathways in the pathogenesis of inflammatory bowel disease

  2015cites this paper
• CGK733-induced LC3 II formation is positively associated with the expression of cyclin-dependent kinase inhibitor p21Waf1/Cip1 through modulation of the AMPK and PERK/CHOP signaling pathways

  2015cites this paper
• Glutathione-S-transferase omega 1 (GSTO1-1) acts as mediator of signaling pathways involved in aflatoxin B1-induced apoptosis-autophagy crosstalk in macrophages.

  2015cites this paper
• Derlin-1 is overexpressed in human colon cancer and promotes cancer cell proliferation

  2015cites this paper
• Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases

  2014cites this paper
• An investigation into the regulation of gene expression in response to ER stress

  2014cites this paper