Multiple-Clones of Streptococcus agalactiae harbouring lnuB gene.

Six S. agalactiae displaying an L-phenotype were recovered from recto-vaginal screening culture from 3 hospitals. S. agalactiae isolates showed susceptible MICs to erythromycin, MIC≤0.12mg/L, and azithromycin, MIC≤0.25mg/L, but resistant MICs to clindamycin, MIC=4mg/L, and lincomycin, MIC=64-128mg/L. Isolates were PCR positive for lnu B gene. Four clones were discriminated by Apa I-PFGE (n): A (3), B (1), C (1) and D (1). Here we describe for the first time the polyclonal emergence of S. agalactiae harboring the lnu B gene in Latin-America.

• Publication year

  2010

• Venue

  Journal of Infection in Developing Countries

• Publication date

  2010-06-29

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3855/JIDC.941PMID 21045372
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC.

  2010cited by this paper
• Prevalence of mef and ermB genes in invasive pediatric erythromycin-resistant Streptococcus pneumoniae isolates from Argentina.

  2009cited by this paper
• Increasing burden of invasive group B streptococcal disease in nonpregnant adults, 1990-2007.

  2009cited by this paper
• Prevalence and mechanisms of erythromycin and clindamycin resistance in clinical isolates of beta-haemolytic streptococci of Lancefield groups A, B, C and G in Seville, Spain.

  2008cited by this paper
• Molecular basis of resistance to macrolides and lincosamides among staphylococci and streptococci from various animal sources collected in the resistance monitoring program BfT-GermVet.

  2007cited by this paper
• Genotypic and phenotypic detection of macrolide and lincosamide resistance in Streptococcus uberis.

  2007cited by this paper
• Erythromycin and Clindamycin Resistance in Group B Streptococcal Clinical Isolates

  2006cited by this paper
• Characterization and mechanisms of resistance of group B streptococcal isolates obtained at a community hospital

  2005cited by this paper
• Multicenter Study of the Mechanisms of Resistance and Clonal Relationships of Streptococcus agalactiae Isolates Resistant to Macrolides, Lincosamides, and Ketolides in Spain

  2005cited by this paper
• Prevalence and Mechanisms of Erythromycin Resistance in Group A and Group B Streptococcus: Implications for Reporting Susceptibility Results

  2004cited by this paper
• Prevalence and Mechanisms of Macrolide Resistance in Invasive and Noninvasive Group B Streptococcus Isolates from Ontario, Canada

  2001cited by this paper
• A New Resistance Gene, linB, Conferring Resistance to Lincosamides by Nucleotidylation in Enterococcus faecium HM1025

  1999cited by this paper
• Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing

  1995cited by this paper

• Macrolide and lincosamide resistance of Streptococcus agalactiae in pregnant women in Poland

  2024cites this paper
• Current research update on group B streptococcal infection related to obstetrics and gynecology

  2024cites this paper
• Comparative analysis of Streptococcus agalactiae S03 and S07 isolated from Schizothorax spp. with different antibiotic resistance and virulence

  2023cites this paper
• Characterization of Streptococcus equi subsp. zooepidemicus isolates containing lnuB gene responsible for the L phenotype

  2023cites this paper
• CLONAL DETECTION OF Streptococcus agalactiae Lehmann AND Neumann PARENTAL STRAINS BY RANDOM AMPLIFICATION OF POLYMORPHIC DNA

  2022cites this paper
• Molecular Characteristics of IS1216 Carrying Multidrug Resistance Gene Cluster in Serotype III/Sequence Type 19 Group B Streptococcus

  2021cites this paper
• Comparative Analysis of Streptococcus Agalactiae S03 and S07 Isolated From Schizothorax Prenanti With Different Antibiotic Resistance and Virulence

  2021cites this paper
• Phenotypic and Genotypic Characterization of Resistance to Macrolides and Lincosamides in Streptococcus agalactiae Isolated from Pregnant Women in Misiones, Argentina.

  2020cites this paper
• A review of antibiotic resistance in Group B Streptococcus: the story so far

  2020influential citation
• New genetic context of lnu(B) composed of two multi-resistance gene clusters in clinical Streptococcus agalactiae ST-19 strains

  2019cites this paper
• Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA

  2017cites this paper
• Emergence of the L phenotype in Group B Streptococci in the South of Ireland

  2017cites this paper
• First clinical isolate in Europe of clindamycin-resistant group B Streptococcus mediated by the lnu(B) gene.

  2014cites this paper
• Molecular Profiles and Antimicrobial Susceptibility of First Isolates of Streptococcus agalactiae Serotype IX in Argentina

  2014cites this paper
• First Case of Streptococcus lutetiensis Bacteremia Involving a Clindamycin-Resistant Isolate Carrying the lnuB Gene

  2013cites this paper
• Group B streptococcal epidemiology and vaccine needs in developed countries.

  2013cites this paper
• The genetic diversity and phenotypic characterisation of Streptococcus agalactiae isolates from Rio de Janeiro, Brazil.

  2011cites this paper