Inhibition of NFκB activation with antioxidants is correlated with reduced cytokine transcription in PTC.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  AJP - Renal Physiology

• Publication date

  1999-11-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1152/ajprenal.1999.277.5.F779PMID 10564243
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pharmacokinetics of N-acetylcysteine in man

  2004cited by this paper
• Induction of monocyte chemoattractant protein-1 by albumin is mediated by nuclear factor kappaB in proximal tubule cells.

  1999cited by this paper
• Activation of NF-kappaB in normal rat kidney epithelial (NRK52E) cells is mediated via a redox-insensitive, calcium-dependent pathway.

  1999cited by this paper
• Inhibition of nuclear factor-κB activation reduces cortical tubulointerstitial injury in proteinuric rats

  1999cited by this paper
• Induction of Monocyte Chemoattractant Protein-1 by Albumin Is Mediated by Nuclear Factor κB in Proximal Tubule Cells

  1999cited by this paper
• Inhibition of nuclear factor-kappaB activation reduces cortical tubulointerstitial injury in proteinuric rats.

  1999cited by this paper
• Pyrrolidine dithiocarbamate augments IL-10, inhibits TNF-alpha, MIP-1alpha, IL-12, and nitric oxide production and protects from the lethal effect of endotoxin.

  1998cited by this paper
• Inhibition of nuclear factor kappa B attenuates proinflammatory cytokine and inducible nitric-oxide synthase expression in postischemic myocardium.

  1998cited by this paper
• Effect of bioflavonoids quercetin and curcumin on ischemic renal injury: a new class of renoprotective agents.

  1998cited by this paper
• Effect of plant flavonoids on immune and inflammatory cell function.

  1998cited by this paper
• Protein overload stimulates RANTES production by proximal tubular cells depending on NF-kappa B activation.

  1998cited by this paper
• Mechanisms of Hyaluronan-Induced Up-Regulation of ICAM-1 and VCAM-1 Expression by Murine Kidney Tubular Epithelial Cells: Hyaluronan Triggers Cell Adhesion Molecule Expression Through a Mechanism Involving Activation of Nuclear Factor-κB and Activating Protein-1

  1998cited by this paper
• Reduction of cisplatin toxicity in cultured renal tubular cells by the bioflavonoid quercetin

  1998cited by this paper
• Mechanisms of hyaluronan-induced up-regulation of ICAM-1 and VCAM-1 expression by murine kidney tubular epithelial cells: hyaluronan triggers cell adhesion molecule expression through a mechanism involving activation of nuclear factor-kappa B and activating protein-1.

  1998cited by this paper
• Low-dose N-acetylcysteine protects rats against endotoxin-mediated oxidative stress, but high-dose increases mortality.

  1998cited by this paper
• Dithiocarbamates enhance tumor necrosis factor-alpha production by rabbit alveolar macrophages, despite inhibition of NF-kappaB.

  1998cited by this paper
• Chloride transport by the rabbit cortical collecting duct: dependence on H,K-ATPase.

  1998cited by this paper
• Evidence suggesting that nitric oxide mediates iron-induced toxicity in cultured proximal tubule cells.

  1998cited by this paper
• PYRROLIDINE DITHIOCARBAMATE AUGMENTS IL-10, INHIBITS TNF-α, MIP-1α, IL-12, AND NITRIC OXIDE PRODUCTION AND PROTECTS FROM THE LETHAL EFFECT OF ENDOTOXIN

  1998cited by this paper
• Identification of clinical and histopathologic risk factors for diminished renal function 2 years posttransplant.

  1998cited by this paper
• Chemotactic factors and renal inflammation.

  1998cited by this paper
• Quercetin, a bioflavonoid, inhibits the induction of interleukin 8 and monocyte chemoattractant protein-1 expression by tumor necrosis factor-alpha in cultured human synovial cells.

  1997cited by this paper
• Ultrastructural localization of osteopontin in the kidney: induction by lipopolysaccharide.

  1997cited by this paper
• Cysteine S-conjugates activate transcription factor NF-kappa B in cultured renal epithelial cells.

  1997cited by this paper
• The Renal Tubule in the Progression of Chronic Renal Failure

  1997cited by this paper
• A role for tissue transglutaminase in hepatic injury and fibrogenesis, and its regulation by NF-kappaB.

  1997cited by this paper
• Enalapril decreases nuclear factor κB activation in the kidney with ureteral obstruction: Rapid Communication

  1997cited by this paper
• Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein.

  1997cited by this paper
• NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

  1997cited by this paper
• Rapid communication. Enalapril decreases nuclear factor kappa B activation in the kidney with ureteral obstruction.

  1997cited by this paper
• Differential regulation of monocytic tumor necrosis factor‐α and interleukin‐10 expression

  1996cited by this paper
• Nitric oxide generation ameliorates the tubulointerstitial fibrosis of obstructive nephropathy.

  1996cited by this paper
• Increased renal atrial natriuretic peptide synthesis in rats with deoxycorticosterone acetate-salt treatment.

  1996cited by this paper
• Glucocorticoid-mediated Gene Suppression of Rat Cytokine-induced Neutrophil Chemoattractant CINC/gro, a Member of the Interleukin-8 Family, through Impairment of NF-B Activation (*)

  1996cited by this paper
• Role of Oxidants and Antioxidants in the Induction of AP-1, NF-κB, and Glutathione S-Transferase Gene Expression*

  1996cited by this paper
• NF-kappa B and transcriptional control of renal epithelial-inducible nitric oxide synthase.

  1995cited by this paper
• NF-κB and transcriptional control of renal epithelial-inducible nitric oxide synthase

  1995cited by this paper
• Activation of NF-kappa B and elevation of MnSOD gene expression by thiol reducing agents in lung adenocarcinoma (A549) cells.

  1995cited by this paper
• Cloning, expression, and functional characterization of rat MIP‐2: a neutrophil chemoattractant and epithelial cell mitogen

  1995cited by this paper
• Role of macrophage inflammatory protein-1 alpha (MIP-1 alpha) in acute lung injury in rats.

  1995cited by this paper
• Mechanisms for the oxygen radical-mediated toxicity of various thiol-containing compounds in cultured mammalian cells.

  1994cited by this paper
• BIOLOGY OF DISEASE - MACROPHAGES AND RENAL-DISEASE

  1994cited by this paper
• Macrophages and renal disease.

  1994cited by this paper
• Comparison of double fluorescence staining and LDH-test for monitoring cell viability in vitro.

  1993cited by this paper
• Regulation of IFN-gamma expression in vivo. IFN-gamma up-regulates expression of its mRNA in normal and lipopolysaccharide-stimulated mice.

  1993cited by this paper
• Modulation of Macrophage Function by Transforming Growth Factor β, Interleukin‐4, and Interleukin‐10 a

  1993cited by this paper
• Synthesis and characterization of rat interleukin-10 (IL-10) cDNA clones from the RNA of cultured OX8- OX22- thoracic duct T cells.

  1992cited by this paper
• Dithiocarbamates as potent inhibitors of nuclear factor kappa B activation in intact cells

  1992cited by this paper
• Structure of the mouse IL-10 gene and chromosomal localization of the mouse and human genes.

  1992cited by this paper
• Rat tumor necrosis factor-alpha. Transcription in rat Kupffer cells and in vitro posttranslational processing based on a PCR-derived cDNA.

  1992cited by this paper
• cDNA cloning by PCR of rat transforming growth factor β-1

  1990cited by this paper
• cDNA cloning by PCR of rat transforming growth factor beta-1.

  1990cited by this paper
• Intracellular thiols regulate activation of nuclear factor kappa B and transcription of human immunodeficiency virus.

  1990cited by this paper
• Oxidation of thiol drugs and biochemicals by the lactoperoxidase/hydrogen peroxide system.

  1987cited by this paper
• Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

  1987cited by this paper
• Cloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequence.

  1986cited by this paper
• Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei.

  1983cited by this paper
• Evaluation of cytotoxicity in cultured cells by enzyme leakage

  1980cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper

• Recent Developments in Formulation Design of a Multifunctional Phytochemical Quercetin: A Review

  2021cites this paper
• The Effect of Southern Indigenous Vegetables on Anti-inflammation

  2016cites this paper
• Effects of Yishen Pinggan Recipe on Renal Protection and NF-κB Signaling Pathway in Spontaneously Hypertensive Rats

  2016cites this paper
• Quercetin modulates toll-like receptor-mediated protein kinase signaling pathways in oxLDL-challenged human PBMCs and regulates TLR-activated atherosclerotic inflammation in hypercholesterolemic rats

  2016cites this paper
• Molecular Stress-inducing Compounds Increase Osteoclast Formation in a Heat Shock Factor 1 Protein-dependent Manner*

  2014cites this paper
• Surfactant protein D inhibits lipopolysaccharide‐induced monocyte chemoattractant protein‐1 expression in human renal tubular epithelial cells: implication for tubulointerstitial fibrosis

  2012cites this paper
• Eicosapentaenoic acid regulates IκBα and prevents tubulointerstitial injury in kidney.

  2011cites this paper
• Quercetin inhibits UV irradiation-induced inflammatory cytokine production in primary human keratinocytes by suppressing NF-κB pathway.

  2011cites this paper
• Induction of interleukin‐10 expression through Fcα receptor in human monocytes and monocyte‐derived dendritic cells: role of p38 MAPKinase

  2010cites this paper
• Evaluation of protective effect of a water-in-oil microemulsion incorporating quercetin against UVB-induced damage in hairless mice skin.

  2010cites this paper
• Quercetin attenuates Monocyte Chemoattractant Protein-1 gene expression in glucose primed aortic endothelial cells through NF-kappaB and AP-1.

  2010cites this paper
• Therapeutic effect of artemisinin on lupus nephritis mice and its mechanisms.

  2010cites this paper
• Effect of Bioflavonoid Quercetin on Endotoxin- Induced Hepatotoxicity and Oxidative Stress in Rat Liver

  2010cites this paper
• Daidzein administration in vivo reduces myocardial injury in a rat ischemia/reperfusion model by inhibiting NF-kappaB activation.

  2009cites this paper
• NF-kappaB signalling in chronic kidney disease.

  2009cites this paper
• Nuclear factor‐κB as a potential therapeutic target for the novel cytotoxic agent LC‐1 in acute myeloid leukaemia

  2008cites this paper
• Post-160-km Race Illness Rates and Decreases in Granulocyte Respiratory Burst and Salivary IgA Output are Not Countered by Quercetin Ingestion

  2008cites this paper
• Inducible nitric oxide synthase as a target of anti-inflammatory treatment modalities

  2008cites this paper
• The differential NF-kB modulation by S-adenosyl-L-methionine, N-acetylcysteine and quercetin on the promotion stage of chemical hepatocarcinogenesis

  2008cites this paper
• Comparative effects of quercetin and its predominant human metabolites on adhesion molecule expression in activated human vascular endothelial cells.

  2008cites this paper
• Anti-inflammatory effects of flavonoids: Genistein, kaempferol, quercetin and daidzein inhibit STAT-1 and NF-kB activation whereas flavone, isorhamnetin, naringenin and pelargonidin inhibit only NF-kB activation along with their inhibitory effect on iNOS expression and NO production in activated mac

  2007cites this paper
• Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated

  2007cites this paper
• CSP-acetylcysteine to ameliorate acute renal injury in a rat ardiopulmonary bypass model

  2007cites this paper
• The effect of flavonoids on transduction mechanisms in lipopolysaccharide-treated human gingival fibroblasts.

  2007cites this paper
• Effects of purple sweet potato anthocyanins on development and intracellular redox status of bovine preimplantation embryos exposed to heat shock.

  2007cites this paper
• N-acetylcysteine to ameliorate acute renal injury in a rat cardiopulmonary bypass model.

  2007cites this paper
• Nutritional control of HIV-AIDS-A case for Selenium

  2007cites this paper
• Genetic engineering of flavonoid biosynthesis in tomato

  2007cites this paper
• DOWN REGULATION OF NF-KAPPA B AS A THERAPEUTIC STRATEGY FOR TYPE 1 DIABETES: EFFECT OF FLAVONOIDS

  2007cites this paper
• The Flavonoid Quercetin Inhibits Proinflammatory Cytokine (Tumor Necrosis Factor Alpha) Gene Expression in Normal Peripheral Blood Mononuclear Cells via Modulation of the NF-κβ System

  2006cites this paper
• Oxidative stress and protective effects of polyphenols: comparative studies in human and rodent kidney. A review.

  2006cites this paper
• Perioperative acute renal failure

  2006cites this paper
• Nutrition and Football : The FIFA/FMARC Consensus on Sports Nutrition

  2006cites this paper
• Studies on novel immunosuppressive agents in experimental arthritis

  2006cites this paper
• Transgenic flavonoid tomato intake reduces C-reactive protein in human C-reactive protein transgenic mice more than wild-type tomato.

  2006cites this paper
• Scoparone inhibits PMA-induced IL-8 and MCP-1 production through suppression of NF-kappaB activation in U937 cells.

  2006cites this paper
• Anti-inflammatory and antinecrotic effects of the volatile anesthetic sevoflurane in kidney proximal tubule cells.

  2006cites this paper
• Nutritional strategies to counter stress to the immune system in athletes, with special reference to football

  2006cites this paper
• Quercetin Attenuates Nuclear Factor- (cid:1) B Activation and Nitric Oxide Production in Interleukin-1 (cid:2) –Activated Rat Hepatocytes 1

  2005cites this paper
• Quercetin attenuates nuclear factor-kappaB activation and nitric oxide production in interleukin-1beta-activated rat hepatocytes.

  2005cites this paper
• Differential effects of albumin on cytokine gene expression in proximal tubular epithelial cells.

  2005cites this paper
• A preliminary in vitro and in vivo study of the effects of new anthraquinones on neutrophils and bone remodeling.

  2005cites this paper
• Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney.

  2005cites this paper
• Renal-associated TLR 2 mediates ischemia / reperfusion injury in the kidney Leemans

  2005cites this paper
• The role of tubulointerstitial inflammation.

  2005cites this paper
• N‐Acetyl Cysteine Regulates TNF‐α‐Inhibited Differentiation in ROS 17/2.8 Osteoblasts

  2004cites this paper
• N-acetyl cysteine regulates TNF-alpha-inhibited differentiation in ROS 17/2.8 osteoblasts.

  2004cites this paper
• Particle bioreactivity and wear-mediated osteolysis.

  2004cites this paper
• Proximal tubule cells stimulated by lipopolysaccharide inhibit macrophage activation.

  2004cites this paper
• Activation of phosphoinositide 3-kinase in response to high glucose leads to regulation of reactive oxygen species-related nuclear factor-kappaB activation and cyclooxygenase-2 expression in mesangial cells.

  2004cites this paper
• Differential Protective Effects of Volatile Anesthetics against Renal Ischemia–Reperfusion Injury In Vivo

  2004cites this paper
• Resveratrol and quercetin down‐regulate tissue factor expression by human stimulated vascular cells

  2003cites this paper
• Pathological Significance of Renal Expression of NF-κB

  2003cites this paper
• The effect of quercetin on the mRNA expression of different antioxidant enzymes in hepatoma cells

  2003cites this paper
• Parenchymal Organ, and Not Splenic, Immunity Correlates with Host Survival during Disseminated Candidiasis

  2003cites this paper
• Detection of nuclear factor-kappaB in IgA nephropathy using Southwestern histochemistry.

  2003cites this paper
• Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells.

  2003cites this paper
• Direct involvement of the receptor-mediated apoptotic pathways in cisplatin-induced renal tubular cell death.

  2003cites this paper
• Pyrrolidine dithiocarbamate reduces renal dysfunction and injury caused by ischemia/reperfusion of the rat kidney.

  2003cites this paper
• Effect of quercetin on hypoxic injury in freshly isolated rat proximal tubules.

  2003cites this paper
• In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production

  2002cites this paper
• Renal damage mediated by oxidative stress: a hypothesis of protective effects of red wine.

  2002cites this paper
• Exposure to particles stimulates superoxide production by human THP-1 macrophages and avian HD-11EM osteoclasts activated by tumor necrosis factor-alpha and PMA.

  2002cites this paper
• Sex differences in the modulation by ethanol of lung chemotaxis.

  2002cites this paper
• In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production.

  2002cites this paper
• Endocytosis of light chains induces cytokines through activation of NF-kappaB in human proximal tubule cells.

  2002cites this paper
• Resuscitation with Ringer's Ethyl Pyruvate Solution Prolongs Survival and Modulates Plasma Cytokine and Nitrite/Nitrate Concentrations in a Rat Model of Lipopolysaccharide-Induced Shock

  2002cites this paper
• Supplementation of N-acetylcysteine normalizes lipopolysaccharide-induced nuclear factor kappaB activation and proinflammatory cytokine production during early rehabilitation of protein malnourished mice.

  2002cites this paper
• Suppression of the TNFα-Induced Increase in IL-1α Expression by Hypochlorite in Human Corneal Epithelial Cells

  2002cites this paper
• Albumin Induces NF-κB Expression in Human Proximal Tubule-Derived Cells (IHKE-1)

  2002cites this paper
• Mercuric ion attenuates nuclear factor-kappaB activation and DNA binding in normal rat kidney epithelial cells: implications for mercury-induced nephrotoxicity.

  2001cites this paper
• Tubular‐interstitial interactions in proteinuric renal diseases

  2001cites this paper
• Cytokine cross-talk between tubular epithelial cells and interstitial immunocompetent cells

  2001cites this paper
• Einfluss von "Calcitonin Gene-Related Peptide" und "Substance P" auf die mRNA-Expression und Freisetzung von Zytokinen aus zerebralen Endothelzellen bei Kostimulation mit Pneumokokkenzellwänden

  2001cites this paper
• Inhibition of Acute and Chronic Inflammatory Responses by the Hydroxybenzoquinonic Derivative Rapanone

  2001cites this paper
• Inhibition of nitric oxide synthase inhibitors and lipopolysaccharide induced inducible NOS and cyclooxygenase‐2 gene expressions by rutin, quercetin, and quercetin pentaacetate in RAW 264.7 macrophages

  2001cites this paper
• Lipoic Acid Confers Protection Against Oxidative Injury in Non-neuronal and Neuronal Tissue

  2001cites this paper
• Involvement of p38 mitogen-activated protein kinase followed by chemokine expression in crescentic glomerulonephritis.

  2001cites this paper
• N-Acetylcysteine downregulates vascular endothelial growth factor production by human keratinocytes in vitro

  2000cites this paper