In vitro studies on cisplatin focusing on kinetic aspects of intracellular chemistry by LC-ICP-MS.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Metallomics

• Publication date

  2013-05-31

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1039/c3mt20251hPMID 23487031
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Accurate quantification of the redox-sensitive GSH/GSSG ratios in the yeast Pichia pastoris by HILIC–MS/MS

  2013cited by this paper
• Interactions of oxaliplatin with the cytoplasmic thiol containing ligand glutathione.

  2012cited by this paper
• Mechanism of cisplatin resistance in human urothelial carcinoma cells.

  2012cited by this paper
• Quantitative determination of intact free cisplatin in cell models by LC-ICP-MS

  2011cited by this paper
• Sample preparation strategies for bioinorganic analysis by inductively coupled plasma mass spectrometry

  2011cited by this paper
• Evaluation of cell lysis methods for platinum metallomic studies of human malignant cells.

  2010cited by this paper
• Determination of cisplatin 1,2-intrastrand guanine-guanine DNA adducts in human leukocytes by high-performance liquid chromatography coupled to inductively coupled plasma mass spectrometry.

  2010cited by this paper
• Analytical methodologies for metallomics studies of antitumor Pt-containing drugs.

  2010cited by this paper
• Platinum speciation used for elucidating activation or inhibition of Pt-containing anti-cancer drugs.

  2010cited by this paper
• Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339

  2010cited by this paper
• Ultra-fast HPLC-ICP-MS analysis of oxaliplatin in patient urine

  2010cited by this paper
• On-line fast column switching SEC × IC separation combined with ICP-MS detection for mapping metallodrug–biomolecule interaction

  2010cited by this paper
• Immunoaffinity assisted LC-ICP-MS—a versatile tool in biomedical research

  2010cited by this paper
• The mechanism of action of platinum anticancer agents--what do we really know about it?

  2009cited by this paper
• Is glutathione the major cellular target of cisplatin? A study of the interactions of cisplatin with cancer cell extracts.

  2009cited by this paper
• Quantification of cisplatin, carboplatin and oxaliplatin in spiked human plasma samples by ICP-SFMS and hydrophilic interaction liquid chromatography (HILIC) combined with ICP-MS detection

  2009cited by this paper
• Platinum compounds 30 years after the introduction of cisplatin: implications for the treatment of ovarian cancer.

  2009cited by this paper
• Cellular accumulation and cytotoxicity of macromolecular platinum complexes in cisplatin-resistant tumor cells.

  2008cited by this paper
• The use of inductively coupled plasma mass spectrometry as a detector in drug metabolism studies

  2008cited by this paper
• The use of inductively coupled plasma mass spectrometry as a detector in drug metabolism studies.

  2008cited by this paper
• Acquisition of Cisplatin-resistance in Malignant Mesothelioma Cells Abrogates Na+,K+,2Cl-;-cotransport Activity and Cisplatin-induced Early Membrane Blebbing

  2008cited by this paper
• Biochemical mechanisms of cisplatin cytotoxicity.

  2007cited by this paper
• Species specific IDMS for accurate quantification of carboplatin in urine by LC-ESI-TOFMS and LC-ICP-QMS

  2007cited by this paper
• The resurgence of platinum-based cancer chemotherapy

  2007cited by this paper
• SEC-ICP-MS and ESI-MS as tools to study the interaction between cisplatin and cytosolic biomolecules

  2007cited by this paper
• Two dimensional separation schemes for investigation of the interaction of an anticancer ruthenium(III) compound with plasma proteins

  2005cited by this paper
• Novel separation method for highly sensitive speciation of cancerostatic platinum compounds by HPLC–ICP–MS

  2005cited by this paper
• Investigation of the reaction of cisplatin with methionine in aqueous media using HPLC-ICP-DRCMS

  2004cited by this paper
• Uptake of antitumor platinum(II)-complexes by cancer cells, assayed by inductively coupled plasma mass spectrometry (ICP-MS).

  2004cited by this paper
• Short-termcis-diamminedichloroplatinum(II) accumulation in sensitive and resistant human ovarian carcinoma cells

  2004cited by this paper
• Electrospray ionization mass spectrometry coupled to liquid chromatography for detection of cisplatin and its hydrated complexes.

  2003cited by this paper
• Cisplatin and platinum drugs at the molecular level. (Review).

  2003cited by this paper
• Application of HPLC-ICP-MS to speciation of cisplatin and its degradation products in water containing different chloride concentrations and in human urine

  2003cited by this paper
• Curing metastatic testicular cancer

  2002cited by this paper
• Kinetic study of the reaction of cisplatin with thiols.

  2002cited by this paper
• Slowing of cisplatin aquation in the presence of DNA but not in the presence of phosphate: improved understanding of sequence selectivity and the roles of monoaquated and diaquated species in the binding of cisplatin to DNA.

  2000cited by this paper
• Development of HPLC conditions for valid determination of hydrolysis products of cisplatin.

  1999cited by this paper
• Structure, Recognition, and Processing of Cisplatin-DNA Adducts.

  1999cited by this paper
• The hydrolysis products of cis-diamminedichloroplatinum(II) 9. Chloride and bromide anation kinetics for some [PtII(N)2(OH2)2]2+ complexes and the structures of [PtIVBr4(N)2] ((N)2 = en, tn)1

  1997cited by this paper
• Cellular distribution and cellular reactivity of platinum (II) complexes.

  1996cited by this paper
• A role of glutathione in resistance mechanisms to cis-diamminedichloroplatinum(ii) in human ovarian-cancer cell-lines in-vitro.

  1995cited by this paper
• The role of cell cycle progression in cisplatin-induced apoptosis in Chinese hamster ovary cells.

  1994cited by this paper
• High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.

  1992cited by this paper
• The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines.

  1991cited by this paper
• DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II).

  1991cited by this paper
• The hydrolysis products of cis-diamminedichloroplatinum(II) 5. The anation kinetics of cis-Pt(X)(NH3)2(OH2)+ (XCl, OH) with glycine, monohydrogen malonate and chloride

  1991cited by this paper
• The hydrolysis products of cis-dichlorodiammineplatinum(II) 2. The kinetics of formation and anation of the cis-diamminedi(aqua)platinum(II) cation

  1989cited by this paper
• NMR study of acid-base equilibria and other reactions of ammineplatinum complexes with aqua and hydroxo ligands

  1989cited by this paper
• The hydrolysis products of cis-diamminedichloroplatinum(II). I. The kinetics of formation and anation of the cis-diammine(aqua)chloroplatinum(II) cation in acidic aqueous solution

  1989cited by this paper
• Glutathione and glutathione-dependent enzymes in ovarian adenocarcinoma cell lines derived from a patient before and after the onset of drug resistance: intrinsic differences and cell cycle effects.

  1988cited by this paper
• Differential potentiation of alkylating and platinating agent cytotoxicity in human ovarian carcinoma cells by glutathione depletion.

  1985cited by this paper
• Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.

  1985cited by this paper
• DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity.

  1979cited by this paper
• Platinum Compounds: a New Class of Potent Antitumour Agents

  1969cited by this paper
• Hard and soft acids and bases, HSAB, part 1: Fundamental principles

  1968cited by this paper
• Hard and soft acids and bases, HSAB, part II: Underlying theories

  1968cited by this paper
• Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode

  1965cited by this paper

• Carrier-Free Cisplatin–Dactolisib Nanoparticles for Enhanced Synergistic Antitumor Efficacy

  2025cites this paper
• Photosubstitution and photoreduction of a diazido platinum(IV) anticancer complex.

  2024cites this paper
• Flow techniques in the analysis of biological samples by inductively coupled plasma mass spectrometry – a review

  2024cites this paper
• Time-Dependent Studies of Oxaliplatin and Other Nucleolar Stress-Inducing Pt(II) Derivatives.

  2022cites this paper
• 00a_NMCV43N11_COVER Spine.indd

  2022cites this paper
• Precise quantitative evaluation of pharmacokinetics of cisplatin using a radio-platinum tracer in tumor-bearing mice

  2022cites this paper
• Facets of ICP-MS and their potential in the medical sciences—Part 1: fundamentals, stand-alone and hyphenated techniques

  2022cites this paper
• Analysis of Renal Platinum Content as a Novel Approach to Protect against Cisplatin Nephrotoxicity: A Review

  2021cites this paper
• Approaches towards understanding the mechanism-of-action of metallodrugs

  2021cites this paper
• Retinal toxicities of Systemic Anticancer Drugs.

  2021cites this paper
• Insights into platinum-induced peripheral neuropathy–current perspective

  2020influential citation
• Heart-cut 2DSEC-RP-LC-ICP-MS as a screening tool in metal-based anticancer research

  2019cites this paper
• The asymmetry of plasma membranes and their cholesterol content influence the uptake of cisplatin

  2019cites this paper
• Lipidoid-Polymer Hybrid Nanoparticles Loaded with TNF siRNA Suppress Inflammation after Intra-articular Administration in a Murine Experimental Arthritis Model.

  2019cites this paper
• Permeation of cisplatin through the membranes of normal and cancer cells: a molecular dynamics study

  2018cites this paper
• Probing the Platinum(IV) Prodrug Hypothesis. Are Platinum(IV) Complexes Really Prodrugs of Cisplatin

  2018cites this paper
• Serum-binding properties of isosteric ruthenium and osmium anticancer agents elucidated by SEC–ICP–MS

  2018cites this paper
• Critical assessment of different methods for quantitative measurement of metallodrug-protein associations

  2018cites this paper
• Speciation of metal drugs, supplements and toxins in media and bodily fluids controls in vitro activities

  2017cites this paper
• Analysis of Drug Active Pharmaceutical Ingredients and Biomolecules Using Triple Quadrupole ICP-MS

  2017cites this paper
• Triphenylphosphane Pt(II) complexes containing biologically active natural polyphenols: Synthesis, crystal structure, molecular modeling and cytotoxic studies.

  2016cites this paper
• Biomedical and Pharmaceutical Applications

  2016cites this paper
• Electrochemistry Coupled to Mass Spectrometry for Investigating Oxidative Metabolism of Pt‐Based Drug Conjugates: A Novel Approach

  2016cites this paper
• Cisplatin versus carboplatin: comparative review of therapeutic management in solid malignancies.

  2016cites this paper
• Kinetics of cisplatin binding to short r(GG) containing miRNA mimics - influence of Na(+)versus K(+), temperature and hydrophobicity on reactivity.

  2015cites this paper
• Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding.

  2015cites this paper
• Capillary electrophoresis in metallodrug development.

  2015cites this paper
• Efeito sinérgico entre a terapia fotodinâmica e a cisplatina: uma nova abordagem para o câncer de colo uterino

  2015cites this paper
• Atomic spectrometry update: review of advances in the analysis of clinical and biological materials, foods and beverages

  2015cites this paper
• Cellular trafficking, accumulation and DNA platination of a series of cisplatin-based dicarboxylato Pt(IV) prodrugs.

  2015cites this paper
• Optimized sample preparation strategy for the analysis of low molecular mass adducts of a fluorescent cisplatin analogue in cancer cell lines by CE‐dual‐LIF

  2015cites this paper
• The study of reduced versus oxidized glutathione in cancer cell models employing isotopically labelled standards

  2014cites this paper
• Low-doses of cisplatin injure hippocampal synapses: a mechanism for 'chemo' brain?

  2014cites this paper
• Synergistic effect of photodynamic therapy and cisplatin: a novel approach for cervical cancer.

  2014cites this paper
• Reactivity of hexanuclear ruthenium metallaprisms towards nucleotides and a DNA decamer

  2014cites this paper
• Copper-transporting proteins and their interactions with platinum-based anticancer substances

  2013cites this paper
• Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking

  2013cites this paper