Anti-Inflammatory, Antiapoptotic and Proproliferative Effects of Vitis vinifera Seed Ethanolic Extract in the Liver of Streptozotocin-Nicotinamide-Induced Type 2 Diabetes in Male Rats.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Canadian Journal of Diabetes

• Publication date

  2017-06-30

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/j.jcjd.2017.04.005PMID 28673757
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Pancreatoprotective effects of Geniotrigona thoracica stingless bee honey in streptozotocin-nicotinamide-induced male diabetic rats.

  2017cited by this paper
• Quercetin ameliorates oxidative stress, inflammation and apoptosis in the heart of streptozotocin-nicotinamide-induced adult male diabetic rats.

  2017cited by this paper
• Investigation of lipid peroxidation and antiapoptotic effects of zinc aganist liver damage in diabetic rats

  2017cited by this paper
• Trans-11 vaccenic acid improves insulin secretion in models of type 2 diabetes in vivo and in vitro.

  2016cited by this paper
• Butanol fraction of Parkia biglobosa (Jacq.) G. Don leaves enhance pancreatic β-cell functions, stimulates insulin secretion and ameliorates other type 2 diabetes-associated complications in rats.

  2016cited by this paper
• Anti-diabetic effect of 3-hydroxy-2-naphthoic acid, an endoplasmic reticulum stress-reducing chemical chaperone.

  2016cited by this paper
• Protective effect of aqueous seed extract of Vitis Vinifera against oxidative stress, inflammation and apoptosis in the pancreas of adult male rats with diabetes mellitus.

  2016cited by this paper
• Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation

  2016cited by this paper
• Mechanisms of Diabetes-Induced Liver Damage: The role of oxidative stress and inflammation.

  2016cited by this paper
• Hepatoprotective effect of grape seed oil against carbon tetrachloride induced oxidative stress in liver of γ-irradiated rat.

  2016cited by this paper
• Antioxidant and Hepatoprotective Effects of Procyanidins from Wild Grape (Vitis amurensis) Seeds in Ethanol-Induced Cells and Rats

  2016cited by this paper
• Methanolic seed extract of Vitis vinifera ameliorates oxidative stress, inflammation and ATPase dysfunction in infarcted and non-infarcted heart of streptozotocin-nicotinamide induced male diabetic rats.

  2016cited by this paper
• Rhinacanthin C ameliorates hyperglycaemia, hyperlipidemia and pancreatic destruction in streptozotocin-nicotinamide induced adult male diabetic rats.

  2016cited by this paper
• Hyperglycemia, oxidative stress, liver damage and dysfunction in alloxan-induced diabetic rat are prevented by Spirulina supplementation.

  2016cited by this paper
• Role of APN and TNF-α in type 2 diabetes mellitus complicated by nonalcoholic fatty liver disease.

  2015cited by this paper
• Hepatoprotective Effects of Grape Seed Procyanidin B2 in Rats With Carbon Tetrachloride-induced Hepatic Fibrosis.

  2015cited by this paper
• Vitis vinifera (Muscat Variety) Seed Ethanolic Extract Preserves Activity Levels of Enzymes and Histology of the Liver in Adult Male Rats with Diabetes

  2015cited by this paper
• Protective Effect of Grape Seed Extract and/or Silymarin Against Thioacetamide-induced Hepatic Fibrosis in Rats

  2015cited by this paper
• Anti-inflammatory effects of grape seed procyanidin B2 on a diabetic pancreas.

  2015cited by this paper
• Terpenes and terpenoids in chemical sensitivity.

  2015cited by this paper
• A pilot, randomized controlled trial to examine the health outcomes of raisin consumption in patients with diabetes.

  2014cited by this paper
• Lipid-lowering and hepatoprotective effects of Vitis vinifera dried seeds on paracetamol-induced hepatotoxicity in rats

  2014cited by this paper
• Grape seed proanthocyanidins ameliorate pancreatic beta-cell dysfunction and death in low-dose streptozotocin- and high-carbohydrate/high-fat diet-induced diabetic rats partially by regulating endoplasmic reticulum stress

  2013cited by this paper
• Decoding cell death signals in liver inflammation.

  2013cited by this paper
• Fisetin, a tetra hydroxy flavone recuperates antioxidant status and protects hepatocellular ultrastructure from hyperglycemia mediated oxidative stress in streptozotocin induced experimental diabetes in rats.

  2013cited by this paper
• The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation.

  2012cited by this paper
• The Potentiality of Grape Seed Extract as a Novel Anti-hepatitis C virus Agent

  2012cited by this paper
• Ameliorative effect of grape seed proanthocyanidin extract on thioacetamide-induced mouse hepatic fibrosis.

  2012cited by this paper
• Molecular Mechanisms of Liver Injury and Hepatocarcinogenesis: Focusing on the Role of Stress-Activated MAPK

  2012cited by this paper
• Interleukin-1 (IL-1) family of cytokines: role in type 2 diabetes.

  2012cited by this paper
• Hepatic steatosis in type 1 diabetes.

  2011cited by this paper
• The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation

  2010cited by this paper
• Contribution of type 1 diabetes to rat liver dysfunction and cellular damage via activation of NOS, PARP, IkappaBalpha/NF-kappaB, MAPKs, and mitochondria-dependent pathways: Prophylactic role of arjunolic acid.

  2010cited by this paper
• Prevalence of nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus.

  2009cited by this paper
• Review of the pharmacological effects of Vitis vinifera (Grape) and its bioactive compounds

  2009cited by this paper
• Quercetin attenuates nuclear factor-kappaB activation and nitric oxide production in interleukin-1beta-activated rat hepatocytes.

  2005cited by this paper
• Quercetin Attenuates Nuclear Factor- (cid:1) B Activation and Nitric Oxide Production in Interleukin-1 (cid:2) –Activated Rat Hepatocytes 1

  2005cited by this paper
• Free Fatty Acids and Cytokines Induce Pancreatic β-Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor-κB and Endoplasmic Reticulum Stress

  2004cited by this paper
• Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

  2004cited by this paper
• Dissection of the multiple mechanisms of TNF‐α‐induced apoptosis in liver injury

  2004cited by this paper
• Dissection of the multiple mechanisms of TNF-alpha-induced apoptosis in liver injury.

  2004cited by this paper
• An introduction to practical biochemistry

  1971cited by this paper

• Effect of Storage on Oil Contents, Fatty Acids, Nutritive Value, Atherogenic, Thrombogenic, Health-promoting İndices and Bioactive Properties of Pastes Produced from Grape Seeds, a Waste of the Wine İndustry

  2025cites this paper
• Nanoparticles from grape seed extract inhibit inflammatory cytokines and ameliorate CCl4-induced hepatotoxicity

  2025cites this paper
• A Novel Therapeutic Strategy for Ameliorating Hyperglycemia‐Induced Liver Injury via Overexpression of the Carboxyl Terminus of HSP70‐Interacting Protein in Wharton's Jelly Mesenchymal Stem Cells

  2025cites this paper
• Chemical Composition and Health Benefits of Grape and Grape Products

  2025cites this paper
• Grape seed extract supplementation in non-alcoholic fatty liver disease.

  2024cites this paper
• Chemical Profiling and Antioxidant, Anti-Inflammatory, Cytotoxic, Analgesic, and Antidiarrheal Activities from the Seeds of Commonly Available Red Grape (Vitis vinifera L.)

  2024influential citation
• Sustainable Intervention: Grape Pomace Flour Ameliorates Fasting Glucose and Mitigates Streptozotocin-Induced Pancreatic Damage in a Type 2 Diabetes Animal Model

  2024cites this paper
• Potential Therapeutic Effect of Sinigrin on Diethylnitrosamine-Induced Liver Cancer in Mice: Exploring the Involvement of Nrf-2/HO-1, PI3K–Akt–mTOR Signaling Pathways, and Apoptosis

  2024cites this paper
• Effect of madecassic acid on retinal oxidative stress, inflammation and Growth Factors in streptozotocin-induced diabetic rats.

  2024cites this paper
• Synergistic Effects of Vitis vinifera L. and Centella asiatica against CCl4-Induced Liver Injury in Mice

  2023cites this paper
• Role of Some Food by Product Extracts Compared to Silymarin as Protective Agents against Acute Liver Injury in Paracetamol Overdose-Exposed Rats

  2023cites this paper
• Sublingual Administration of Teucrium polium-Loaded Nanofibers with Ultra-Fast Release in the Treatment of Diabetes Mellitus: In Vitro and In Vivo Evaluation.

  2023cites this paper
• Corinthian Currants Supplementation Restores Serum Polar Phenolic Compounds, Reduces IL-1beta, and Exerts Beneficial Effects on Gut Microbiota in the Streptozotocin-Induced Type-1 Diabetic Rat

  2023cites this paper
• Polyphenol Characterization and Antioxidant Activity of Grape Seeds and Skins from Sicily: A Preliminary Study

  2022cites this paper
• Hepatoprotective effect of pinostrobin against thioacetamide-induced liver cirrhosis in rats

  2022cites this paper
• A systematic review on hepatoprotective potential of grape and polyphenolic compounds: molecular mechanism and future prospective

  2022cites this paper
• Antidiabetic herbal biomolecules

  2022cites this paper
• Potential of fruits and vegetables to treat inflammatory conditions

  2021cites this paper
• Health Beneficial Properties of Grapevine Seed Extract and Its Influence on Selected Biochemical Markers in the Blood, Liver and Kidneys of Rattus norvegicus

  2021cites this paper
• Bicyclol Regulates Hepatic Gluconeogenesis in Rats with Type 2 Diabetes and Non-alcoholic Fatty Liver Disease by Inhibiting Inflammation

  2021cites this paper
• Marantodes pumilum (Blume) Kuntze (Kacip Fatimah) leaves aqueous extract prevents downregulation of Wnt/β-catenin pathway and upregulation of apoptosis in osteoblasts of estrogen-deficient, diabetes-induced rats.

  2021cites this paper
• Marantodes pumilum Var Alata (Kacip Fatimah) ameliorates derangement in RANK/RANKL/OPG pathway and reduces inflammation and oxidative stress in the bone of estrogen-deficient female rats with type-2 diabetes.

  2021cites this paper
• Ethanolic extract of Salacca zalacca peel reduce IL-1β and apoptosis in high glucose induced zebrafish embryo

  2021cites this paper
• STUDY OF HEPATOPROTECTIVE ACTIVITY OF STINGLESS BEE PROPOLIS AGAINTS TOXICITY OF DRUGS

  2021cites this paper
• Reduction of blood glucose by plant extracts and their use in the treatment of diabetes mellitus; discrepancies in effectiveness between animal and human studies.

  2020cites this paper
• Oral administration of Centella asiatica (L.) Urb leave aqueous extract ameliorates cerebral oxidative stress, inflammation, and apoptosis in male rats with type-2 diabetes

  2020cites this paper
• The effect of combination of regular continuous exercise and resveratrol supplementation on some regulatory and executive factors of hepatocytic apoptosis in male diabetic rats

  2020cites this paper
• Topical administration of mangiferin promotes healing of the wound of streptozotocin-nicotinamide-induced type-2 diabetic male rats

  2020cites this paper
• Pterocarpus mildbraedii (Harms) extract resolves propanil-induced hepatic injury via repression of inflammatory stress responses in Wistar rats.

  2020cites this paper
• A Review on Mechanistic and pharmacological findings of Diabetic Peripheral Neuropathy including Pharmacotherapy.

  2020cites this paper
• Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers

  2020cites this paper
• Protective role of wogonin against cadmium induced testicular toxicity: Involvement of antioxidant, anti-inflammatory and anti-apoptotic pathways.

  2020cites this paper
• The Effects of Urtica dioica and Lamium album Extracts on the Expression Level of Cyclooxygenase-2 and Caspase-3 in the Liver and Kidney of Streptozotocin-Induced Diabetic Rats

  2019cites this paper
• Marantodes pumilum (Blume) Kuntze (Kacip Fatimah) stimulates uterine contraction in rats in post-partum period.

  2019cites this paper
• Antidiabetic, Antihyperlipidemic, Antioxidant, Anti-inflammatory Activities of Ethanolic Seed Extract of Annona reticulata L. in Streptozotocin Induced Diabetic Rats

  2019cites this paper
• Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin‐induced diabetic rats

  2018cites this paper
• Evaluation of the Anti‐Diabetic Activity of Polysaccharide from Cordyceps cicadae in Experimental Diabetic Rats

  2018cites this paper
• The effect of aqueous extract of grapevine leaf (Vitis vinifera) on pathologic feature of the pancreas in type-1 experimental diabetes: a different approach to medicinal plants

  2018cites this paper
• Grape seed extracts attenuate retinal Müller cell gliosis in streptozotocin-diabetic rats

  2018cites this paper
• Hormonal control of vas deferens fluid volume and aquaporin expression in rats

  2018cites this paper
• Bioactive Compounds and Extracts from Traditional Herbs and Their Potential Anti-Inflammatory Health Effects

  2018cites this paper
• ، 1396 The level of gene expression of Bax and Bcl-2 and the activity of caspase 3 in the liver tissues of normal, type 1 and type 2 diabetic rats before and after treatment with aqueous extract

  2017cites this paper
• Marantodes pumilum (Kacip fatimah) enhances in-vitro glucose uptake in 3T3-L1 adipocyte cells and reduces pancreatic complications in streptozotocin-nicotinamide induced male diabetic rats.

  2017cites this paper
• The level of gene expression of Bax and Bcl-2 and the activity of caspase 3 in the liver tissues of normal, type 1 and type 2 diabetic rats before and after treatment with aqueous extract of garlic

  2017cites this paper