An IgaA/UmoB Family Protein from Serratia marcescens Regulates Motility, Capsular Polysaccharide Biosynthesis, and Secondary Metabolite Production

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Applied and Environmental Microbiology

• Publication date

  2018-01-05

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1128/AEM.02575-17PMID 29305504PMCID PMC5835751
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2015influential reference
• Antimicrobial activity of prodigiosin isolated from Serratia marcescens UFPEDA 398

  2015cited by this paper
• Insights on the human microbiome and its xenobiotic metabolism: what is known about its effects on human physiology?

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  2008influential reference
• Catabolite repression control of flagellum production by Serratia marcescens.

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  1992cited by this paper
• Regulation of capsular polysaccharide synthesis in Escherichia coli K12

  1991cited by this paper
• Fractal spreading growth of Serratia marcescens which produces surface active exolipids.

  1989cited by this paper
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  1988cited by this paper
• Insect pathogenic properties of Serratia marcescens: phage-resistant mutants with a decreased resistance to Cecropia immunity and a decreased virulence to Drosophila.

  1980cited by this paper
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  1962cited by this paper
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  1961cited by this paper
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