Alpha-Synuclein Expression in the Developing Human Brain

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Pediatric and Developmental Pathology

• Publication date

  2004-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/s10024-003-7080-9PMID 15547775
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Differential expression and distribution of alpha-, beta-, and gamma-synuclein in the developing human substantia nigra.

  2001cited by this paper
• Differential Expression and Distribution of α-, β-, and γ-Synuclein in the Developing Human Substantia Nigra

  2001cited by this paper
• Alpha‐Synuclein Expression in Central Nervous System Tumors Showing Neuronal or Mixed Neuronal/Glial Differentiation

  2000cited by this paper
• α-Synuclein is expressed in a variety of brain tumors showing neuronal differentiation

  2000cited by this paper
• Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system.

  2000cited by this paper
• Mouse models of α-synucleinopathy and Lewy pathology

  2000cited by this paper
• Mice Lacking a-Synuclein Display Functional Deficits in the Nigrostriatal Dopamine

  2000cited by this paper
• Synucleins Are Developmentally Expressed, and α-Synuclein Regulates the Size of the Presynaptic Vesicular Pool in Primary Hippocampal Neurons

  2000cited by this paper
• Chicken synucleins: cloning and expression in the developing embryo.

  2000cited by this paper
• Alpha-synuclein and Parkinson's disease: selective neurodegenerative effect of alpha-synuclein fragment on dopaminergic neurons in vitro and in vivo.

  2000cited by this paper
• C-terminal α-synuclein immunoreactivity in structures other than Lewy bodies in neurodegenerative disorders

  2000cited by this paper
• Mouse models of alpha-synucleinopathy and Lewy pathology.

  2000cited by this paper
• α‐Synuclein and Parkinson's disease: Selective neurodegenerative effect of α‐synuclein fragment on dopaminergic neurons in vitro and in vivo

  2000cited by this paper
• Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary

  2000cited by this paper
• Argyrophilic glial inclusions in the midbrain of patients with Parkinson's disease and diffuse Lewy body disease are immunopositive for NACP/alpha-synuclein.

  1999cited by this paper
• Neural expression profile of alpha-synuclein in developing human cortex.

  1999cited by this paper
• Synucleins in synaptic plasticity and neurodegenerative disorders

  1999cited by this paper
• Developmental expression of alpha-synuclein in rat hippocampus and cerebral cortex.

  1999cited by this paper
• Synoretin--A new protein belonging to the synuclein family.

  1999cited by this paper
• Argyrophilic glial inclusions in the midbrain of patients with Parkinson's disease and diffuse Lewy body disease are immunopositive for NACP/α-synuclein

  1999cited by this paper
• Axon pathology in Parkinson's disease and Lewy body dementia hippocampus contains alpha-, beta-, and gamma-synuclein.

  1999cited by this paper
• Developmental expression of α-synuclein in rat hippocampus and cerebral cortex

  1999cited by this paper
• Choroid plexus epithelium (normal and neoplastic) expresses synaptophysin. A potentially useful aid in differentiating carcinoma of the choroid plexus from metastatic papillary carcinomas.

  1999cited by this paper
• The cDNA cloning and ontogeny of mouse α‐synuclein

  1998cited by this paper
• The synuclein family.

  1998cited by this paper
• The cDNA cloning and ontogeny of mouse alpha-synuclein.

  1998cited by this paper
• The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease.

  1998cited by this paper
• Expression Pattern of Synucleins (Non‐Aβ Component of Alzheimer's Disease Amyloid Precursor Protein/α‐Synuclein) During Murine Brain Development

  1998cited by this paper
• Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development.

  1998cited by this paper
• Abnormal accumulation of NACP/alpha-synuclein in neurodegenerative disorders.

  1998cited by this paper
• Alpha synuclein in neurodegenerative disorders: Murderer or accomplice?

  1998cited by this paper
• Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

  1997cited by this paper
• Phosphorylation of microtubule-associated protein tau on Ser 262 by an embryonic 100 kDa protein kinase.

  1997cited by this paper
• Mutation in the alpha-synuclein gene identified in families with Parkinson's disease.

  1997cited by this paper
• Characterization of a novel protein regulated during the critical period for song learning in the zebra finch.

  1995cited by this paper
• The precursor protein of non-Aβ component of Alzheimer's disease amyloid is a presynaptic protein of the central nervous system

  1995cited by this paper
• Identification of two distinct synucleins from human brain

  1994cited by this paper
• The extent of phosphorylation of fetal tau is comparable to that of PHF-tau from Alzheimer paired helical filaments.

  1993cited by this paper
• Immunohistochemical distribution of amyloid precursor protein during normal rat development.

  1993cited by this paper

• Distinct cellular localization of α- synuclein and β-synuclein in the chick retina

  2025cites this paper
• Revisiting the advance of age-dependent α-synuclein propagation and aggregation

  2025cites this paper
• Alpha-synuclein expression in anterior pituitary cells of aged cattle.

  2025cites this paper
• Lewy body dementia: exploring biomarkers and pathogenic interactions of amyloid β, tau, and α-synuclein

  2025cites this paper
• The Role of Alpha-Synuclein in Neurodevelopmental Diseases

  2024cites this paper
• Alpha-synuclein expression in oxytocin neurons of young and old bovine brains

  2024cites this paper
• Alpha-synuclein expression in GnRH neurons of young and old bovine hypothalami.

  2024cites this paper
• Inactive S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in human stem cell model of Parkinson’s disease

  2023cites this paper
• It’s a TRIM-endous view from the top: the varied roles of TRIpartite Motif proteins in brain development and disease

  2023cites this paper
• Nuclease-dead S. aureus Cas9 downregulates alpha-synuclein and reduces mtDNA damage and oxidative stress levels in patient-derived stem cell model of Parkinson’s disease

  2023cites this paper
• Priming mesenchymal stem cells with α-synuclein enhances neuroprotective properties through induction of autophagy in Parkinsonian models

  2022cites this paper
• Functional interaction between α-synuclein and Nurr1 in dopaminergic neurons.

  2022cites this paper
• Prion-like α-synuclein pathology in the brain of infants with Krabbe disease

  2022cites this paper
• Prion-like α-synuclein pathology in the brains of infants: Krabbe disease as a novel seed-competent α-synucleinopathy

  2021cites this paper
• Internalization of α-synuclein oligomers into SH-SY5Y cells.

  2021cites this paper
• The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders

  2020cites this paper
• Bifluorescent Analysis of ⍺-Synuclein Aggregation In Vivo

  2020cites this paper
• Mitochondrial-associated protein biomarkers in patients with attention-deficit/hyperactivity disorder.

  2019cites this paper
• Loss of prostatic acid phosphatase and α-synuclein cause motor circuit degeneration without altering cerebellar patterning

  2019cites this paper
• Human NPCs can degrade α-syn fibrils and transfer them preferentially in a cell contact-dependent manner possibly through TNT-like structures.

  2019cites this paper
• Central neurocytoma represents a tumor consisting of diverse neuronal phenotypes.

  2018cites this paper
• Chromatin-Bound Oxidized α-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson’s Disease

  2017cites this paper
• Complex Effects of the ZSCAN21 Transcription Factor on Transcriptional Regulation of α-Synuclein in Primary Neuronal Cultures and in Vivo*

  2016cites this paper
• Loss of Functional Alpha-Synuclein: A Toxic Event in Parkinson’s Disease?

  2016cites this paper
• Modelling synucleinopathies with human neurons derived from embryonic stem cells over-expressing α-Synuclein

  2016cites this paper
• Study of the transcriptional regulation of α-synuclein

  2015cites this paper
• The Prion Hypothesis of Parkinson’s Disease

  2015cites this paper
• Expression of alpha-synuclein during eye development of mice (Mus musculus), chick (Gallus gallus domisticus) and fish (Ctenopharyngodon idella) in a comparison study.

  2015cites this paper
• The paths to neurodegeneration in genetic Parkinson's disease.

  2014cites this paper
• Somatic Alpha-Synuclein Mutations in Parkinson's Disease: Hypothesis and Preliminary Data

  2013influential citation
• Alpha-Synuclein Transmission and Mitochondrial Toxicity in Primary Human Foetal Enteric Neurons In Vitro

  2013cites this paper
• Clinical neuropathology practice guide 5-2013: markers of neuronal maturation

  2013cites this paper
• Alpha-synuclein promotes early neurite outgrowth in cultured primary neurons

  2013cites this paper
• Role of Alpha-Synuclein Protein Levels in Mitochondrial Morphology and Cell Survival in Cell Lines

  2012cites this paper
• Alpha-synuclein and the multiple hit hypothesis of Parkinson's disease

  2012influential citation
• Reciprocal Induction Between α-Synuclein and β-Amyloid in Adult Rat Neurons

  2012cites this paper
• The child is father to the man: Developmental roles for proteins of importance for neurodegenerative disease

  2010cites this paper
• Clues to how alpha‐synuclein damages neurons in Parkinson's disease

  2010cites this paper
• Cerebrospinal Fluid Biomarkers for Dementia with Lewy Bodies

  2010cites this paper
• Patterns of synuclein expression throughout lens development

  2010cites this paper
• Controlling the mass action of α‐synuclein in Parkinson’s disease

  2008cites this paper
• Alpha-Synuclein mRNA Levels Correspond to Beck Depression Inventory Scores in Females with Eating Disorders

  2008cites this paper
• α-Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice

  2008cites this paper
• Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease.

  2007cites this paper
• Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation.

  2007cites this paper
• Silencing of human alpha-synuclein in vitro and in rat brain using lentiviral-mediated RNAi.

  2006cites this paper
• Silencing of human α-synuclein in vitro and in rat brain using lentiviral-mediated RNAi

  2006cites this paper
• Proteomic analysis of the genotoxicant methylazoxymethanol (MAM)-induced changes in the developing cerebellum.

  2006cites this paper