Structural, biochemical, and cell biological aspects of the serine proteinase inhibitor SKALP/elafin/ESI.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Biological Chemistry Hoppe-Seyler

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1515/BCHM3.1995.376.1.1PMID 7612183
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Topographic relation between skin-derived antileukoproteinase (SKALP) and leukocyte elastase in a case of annular pustular psoriasis.

  1995cited by this paper
• Assignment of the human gene encoding the epidermal serine proteinase inhibitor SKALP (PI3) to chromosome region 20q12-->q13.

  1994cited by this paper
• SKALP/elafin is an inducible proteinase inhibitor in human epidermal keratinocytes.

  1994cited by this paper
• Regulation of secretory leukocyte proteinase inhibitor (SLPI) and elastase-specific inhibitor (ESI/elafin) in human airway epithelial cells by cytokines and neutrophilic enzymes.

  1994cited by this paper
• Up-regulation of elafin/SKALP gene expression in psoriatic epidermis.

  1994cited by this paper
• Demonstration of skin‐derived antileukoproteinase (skalp) and its target enzyme human leukocyte elastase in squamous cell carcinoma

  1994cited by this paper
• Crystallization of a complex between an elastase-specific inhibitor elafin and porcine pancreatic elastase.

  1993cited by this paper
• Differential expression of SKALP/Elafin in human epidermal tumors.

  1993cited by this paper
• Characterization and gene sequence of the precursor of elafin, an elastase-specific inhibitor in bronchial secretions.

  1993cited by this paper
• Immunohistochemical localization of SKALP/elafin in psoriatic epidermis.

  1993cited by this paper
• SKALP/elafin: an elastase inhibitor from cultured human keratinocytes. Purification, cDNA sequence, and evidence for transglutaminase cross-linking.

  1993cited by this paper
• Kinetics of the inhibition of human leukocyte elastase by elafin, a 6-kilodalton elastase-specific inhibitor from human skin.

  1993cited by this paper
• Secretion of mucus proteinase inhibitor and elafin by Clara cell and type II pneumocyte cell lines.

  1993cited by this paper
• Synthesis and structure-activity relationships of elafin, an elastase-specific inhibitor.

  1992cited by this paper
• Primary structure of the human elafin precursor preproelafin deduced from the nucleotide sequence of its gene and the presence of unique repetitive sequences in the prosegment.

  1992cited by this paper
• Demonstration of skin-derived antileukoproteinase (SKALP) in urine of psoriatic patients.

  1992cited by this paper
• Isolation of elafin and elastase-specific inhibitor (ESI) from bronchial secretions. Evidence of sequence homology and immunological cross-reactivity.

  1992cited by this paper
• Phosphorylated cystatin α is a natural substrate of epidermal transglutaminase for formation of skin cornified envelope

  1992cited by this paper
• Purification and characterization of elastase-specific inhibitor. Sequence homology with mucus proteinase inhibitor.

  1991cited by this paper
• Skin-derived antileukoproteinase (SKALP), an elastase inhibitor from human keratinocytes. Purification and biochemical properties.

  1991cited by this paper
• Distribution of skin‐derived antileucoproteases (SKALP) in the marginal zone of the spreading psoriatic lesion

  1991cited by this paper
• Elafin is a potent inhibitor of proteinase 3.

  1991cited by this paper
• Elastase-inhibiting activity in scaling skin disorders.

  1990cited by this paper
• Proteinase inhibitory activities of antileukoprotease are represented by its second COOH-terminal domain.

  1990cited by this paper
• Elafin: an elastase-specific inhibitor of human skin. Purification, characterization, and complete amino acid sequence.

  1990cited by this paper
• Four disulfide bonds' allocation of Na+, K(+)-ATPase inhibitor (SPAI).

  1990cited by this paper
• Skin‐derived antileucoproteases (SKALPs): characterization of two new elastase inhibitors from psoriatic epidermis

  1990cited by this paper
• Androgens affect the processing of secretory protein precursors in the guinea pig seminal vesicle. II. Identification of conserved sites for protein processing.

  1989cited by this paper
• The scanning model for translation: an update

  1989cited by this paper
• Tissue destruction by neutrophils.

  1989cited by this paper
• Translational activation of the lck proto-oncogene

  1988cited by this paper
• Enzymatic quantification of polymorphonuclear leucocytes in normal and psoriatic skin following standardized injury

  1988cited by this paper
• Human mucus proteinase inhibitor (human MPI). Human seminal inhibitor I (HUSI-I), antileukoprotease (ALP), secretory leukocyte protease inhibitor (SLPI).

  1988cited by this paper
• The 2.5 A X‐ray crystal structure of the acid‐stable proteinase inhibitor from human mucous secretions analysed in its complex with bovine alpha‐chymotrypsin.

  1988cited by this paper
• Transcending the impenetrable: how proteins come to terms with membranes.

  1988cited by this paper
• An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs.

  1987cited by this paper
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  1987cited by this paper
• The major clotting protein from guinea pig seminal vesicle contains eight repeats of a 24-amino acid domain.

  1987cited by this paper
• Isolation, properties, and complete amino acid sequence of human secretory leukocyte protease inhibitor, a potent inhibitor of leukocyte elastase.

  1986cited by this paper
• Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin

  1986cited by this paper
• Molecular cloning and expression of cDNA for human antileukoprotease from cervix uterus.

  1986cited by this paper
• The acid‐stable proteinase inhibitor of human mucous secretions (HUSI‐I, antileukoprotease)

  1986cited by this paper
• Characterization of a low molecular weight anti-elastase isolated from human bronchial secretion.

  1985cited by this paper
• False starts in translational control of gene expression

  1985cited by this paper
• Physiological roles of protein inhibitors

  1984cited by this paper
• Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.

  1983cited by this paper
• Human plasma proteinase inhibitors.

  1983cited by this paper
• A catalogue of splice junction sequences.

  1982cited by this paper
• Comparative sequence analysis of the mRNAs coding for mouse and rat whey protein.

  1982cited by this paper
• An elastase-specific inhibitor from human bronchial mucus. Isolation and characterization.

  1981cited by this paper
• The toxin-agglutinin fold. A new group of small protein structures organized around a four-disulfide core.

  1980cited by this paper
• Mendelian Inheritance in Man. Catalogs of Autosomal Dominant, Autosomal Recessive, and X-Linked Phenotypes

  1972cited by this paper

• The Role of Secretory Leukocyte Proteinase Inhibitor During Transplantation

  2019cites this paper
• Alarm anti‐protease trappin‐2 negatively correlates with proinflammatory cytokines in patients with periodontitis

  2017cites this paper
• From sequence to function: Understanding of genetic risk factors for psoriasis and atopic dermatitis

  2017cites this paper
• Late cornified envelope (LCE) proteins: distinct expression patterns of LCE2 and LCE3 members suggest nonredundant roles in human epidermis and other epithelia

  2016cites this paper
• Periodontal Disease and Gingival Innate Immunity – Who Has the Upper Hand ? 71 Periodontal disease

  2012cites this paper
• Periodontal Disease and Gingival Innate Immunity – Who Has the Upper Hand?

  2012cites this paper
• Protease inhibitor levels in periodontal health and disease.

  2012cites this paper
• Modulation and function of microglial phenotypes

  2012cites this paper
• The Novel Activated Microglia/Macrophage WAP Domain Protein, AMWAP, Acts as a Counter-Regulator of Proinflammatory Response

  2010cites this paper
• Étude du mode d'action antimicrobien de la pré-élafine contre Pseudomonas aeruginosa

  2010cites this paper
• Evolution of trappin genes in mammals

  2010cites this paper
• Human Pre-Elafin Inhibits a Pseudomonas aeruginosa -Secreted Peptidase and Prevents Its Proliferation in Complex Media (cid:1)

  2008cites this paper
• Characterization of human pre-elafin mutants: full antipeptidase activity is essential to preserve lung tissue integrity in experimental emphysema.

  2007cites this paper
• Human Pre-Elafin Inhibits a Pseudomonas aeruginosa-Secreted Peptidase and Prevents Its Proliferation in Complex Media

  2007cites this paper
• Inflammation and stroke: therapeutic effects of adenoviral expression of secretory Leukocyte Protease Inhibitor.

  2006cites this paper
• Increased local levels of granulocyte colony-stimulating factor are associated with the beneficial effect of pre-elafin (SKALP/trappin-2/WAP3) in experimental emphysema

  2006cites this paper
• Proteins with whey-acidic-protein motifs and cancer.

  2006cites this paper
• The serine protease inhibitor trappin-2 is present in cartilage and synovial fluid in osteoarthritis.

  2006cites this paper
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  2005cites this paper
• Current synthetic inhibitors of human neutrophil elastase in 2005

  2005cites this paper
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  2004cites this paper
• Androgen-Dependent Expression, Gene Structure, and Molecular Evolution of Guinea Pig Caltrin II, a WAP-Motif Protein1

  2004cites this paper
• Increased plasma levels of serine proteinase inhibitors in lung cancer patients.

  2004cites this paper
• Up-regulation of secretory leukocyte protease inhibitor (SLPI) in the brain after ischemic stroke: adenoviral expression of SLPI protects brain from ischemic injury.

  2003influential citation
• Identification by subtractive suppression hybridization of bacteria-induced genes expressed in Manduca sexta fat body.

  2003cites this paper
• Elafin expression in human fetal and adult submandibular glands

  2002cites this paper
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  2002cites this paper
• Inhibition of human neutrophil elastase-induced acute lung injury in hamsters by recombinant human pre-elafin (trappin-2).

  2002cites this paper
• Immunohistochemical expression of SKALP/elafin in squamous cell carcinoma of human lung.

  2002cites this paper
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  2002cites this paper
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  2001cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  1999cites this paper
• Targeted overexpression of elafin protects mice against cardiac dysfunction and mortality following viral myocarditis.

  1999influential citation
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  1999cites this paper
• Human neutrophil elastase regulates the expression and secretion of elafin (elastase‐specific inhibitor) in type II alveolar epithelial cells

  1999cites this paper
• Elastase Inhibitors in the Lung: Expression and Functional Relationships

  1999cites this paper
• Evolution of the trappin multigene family in the Suidae.

  1998cites this paper
• SKALP/elafin gene polymorphisms are not associated with pustular forms of psoriasis

  1998cites this paper
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  1997cites this paper
• Purification and characterization of a novel Kazal-type serine proteinase inhibitor of neutrophil elastase from sheep lung.

  1997cites this paper
• Epidermal structural proteins in skin disorders.

  1997cites this paper
• Characterization of a novel elastase inhibitor from a fan coral.

  1996cites this paper
• Accelerated Evolution in Inhibitor Domains of Porcine Elafin Family Members (*)

  1996cites this paper
• Molecular and cell biological characterization of the serine proteinase inhibitor SKALP

  1995cites this paper