A review of fluorescent ligands for studying 5-HT3 receptors.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Neuropharmacology

• Publication date

  2015-04-16

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/j.neuropharm.2015.04.002PMID 25892507
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tracking individual membrane proteins and their biochemistry: The power of direct observation.

  2015cited by this paper
• Characterizing new fluorescent tools for studying 5-HT₃ receptor pharmacology.

  2015cited by this paper
• Investigating ion channel conformational changes using voltage clamp fluorometry.

  2015cited by this paper
• Bright Building Blocks for Chemical Biology

  2014cited by this paper
• X-ray structure of the mouse serotonin 5-HT3 receptor

  2014cited by this paper
• Discriminating between 5-HT3A and 5-HT3AB receptors

  2013cited by this paper
• A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins.

  2013cited by this paper
• Recent developments in 5-HT3 receptor pharmacology.

  2013cited by this paper
• Antibody-induced acetylcholine receptor clusters inhabit liquid-ordered and liquid-disordered domains.

  2013cited by this paper
• Characterization and validation of fluorescent receptor ligands: a case study of the ionotropic serotonin receptor.

  2013cited by this paper
• Large scale expression and purification of the mouse 5-HT3 receptor.

  2013cited by this paper
• Partial agonism of 5-HT3 receptors: a novel approach to the symptomatic treatment of IBS-D.

  2013cited by this paper
• High-throughput fluorescence polarization assay of ligand binding to IP3 receptors.

  2013cited by this paper
• The 5-HT 3 AB Receptor Shows an A 3 B 2 Stoichiometry at the Plasma Membrane

  2013cited by this paper
• Near native binding of a fluorescent serotonin conjugate to serotonin type 3 receptors.

  2013cited by this paper
• The 5-HT3AB receptor shows an A3B2 stoichiometry at the plasma membrane.

  2013cited by this paper
• A caged, localizable rhodamine derivative for superresolution microscopy.

  2012cited by this paper
• High-affinity fluorescent ligands for the 5-HT3 receptor

  2012cited by this paper
• Switchable fluorophores for protein labeling in living cells.

  2011cited by this paper
• Therapeutics of 5-HT3 receptor antagonists: current uses and future directions.

  2011cited by this paper
• Small photoactivatable molecules for controlled fluorescence activation in living cells.

  2011cited by this paper
• The structural basis of function in Cys-loop receptors

  2010cited by this paper
• Toward Biophysical Probes for the 5-HT3 Receptor: Structure−Activity Relationship Study of Granisetron Derivatives

  2010cited by this paper
• 5-HT(3) receptors: role in disease and target of drugs.

  2010cited by this paper
• Single-molecule imaging of a fluorescent unnatural amino acid incorporated into nicotinic receptors.

  2009cited by this paper
• Bioorthogonal chemistry: fishing for selectivity in a sea of functionality.

  2009cited by this paper
• Identification of a fluorescent general anesthetic, 1-aminoanthracene

  2009cited by this paper
• Specific fluorescent detection of fibrillar α-synuclein using mono- and trimethine cyanine dyes

  2008cited by this paper
• Specific fluorescent detection of fibrillar alpha-synuclein using mono- and trimethine cyanine dyes.

  2008cited by this paper
• GABAA receptor trafficking and its role in the dynamic modulation of neuronal inhibition

  2008cited by this paper
• BODIPY dyes and their derivatives: syntheses and spectroscopic properties.

  2007cited by this paper
• The 5-HT3 receptor as a therapeutic target

  2007cited by this paper
• Repetitive reversible labeling of proteins at polyhistidine sequences for single-molecule imaging in live cells.

  2007cited by this paper
• Mutagenesis and Molecular Modeling Reveal the Importance of the 5-HT3 Receptor F-loop*

  2006cited by this paper
• The Fluorescent Toolbox for Assessing Protein Location and Function

  2006cited by this paper
• Ligand Binding Transmits Conformational Changes across the Membrane‐Spanning Region to the Intracellular Side of the 5‐HT3 Serotonin Receptor

  2005cited by this paper
• Refined structure of the nicotinic acetylcholine receptor at 4A resolution.

  2005cited by this paper
• A guide to choosing fluorescent proteins

  2005cited by this paper
• Short tetracysteine tags to beta-tubulin demonstrate the significance of small labels for live cell imaging.

  2004cited by this paper
• Reversible site-selective labeling of membrane proteins in live cells

  2004cited by this paper
• Noninvasive Imaging of 5-HT3 Receptor Trafficking in Live Cells

  2004cited by this paper
• Characterization of the Ligand-binding Site of the Serotonin 5-HT3 Receptor

  2003cited by this paper
• Monitoring expression and clustering of the ionotropic 5HT3 receptor in plasma membranes of live biological cells.

  2003cited by this paper
• Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E.

  2003cited by this paper
• In Vitro and In Vivo Ligand Binding to the 5HT3 Serotonin Receptor Characterised by Time‐Resolved Fluorescence Spectroscopy

  2001cited by this paper
• Mapping the antagonist binding site of the serotonin type 3 receptor by fluorescence resonance energy transfer.

  2001cited by this paper
• High Throughput Fluorescence Polarization: A Homogeneous Alternative to Radioligand Binding for Cell Surface Receptors

  2000cited by this paper
• Study of ligand-receptor interactions by fluorescence correlation spectroscopy with different fluorophores: evidence that the homopentameric 5-hydroxytryptamine type 3As receptor binds only one ligand.

  1999cited by this paper
• High Calcium Permeability of Serotonin 5‐HT3 Receptors on Presynaptic Nerve Terminals from Rat Striatum

  1998cited by this paper
• Ligand binding to the serotonin 5HT3 receptor studied with a novel fluorescent ligand.

  1998cited by this paper
• Binding, gating, affinity and efficacy: The interpretation of structure‐activity relationships for agonists and of the effects of mutating receptors

  1998cited by this paper
• Screening ligands for membrane protein receptors by total internal reflection fluorescence: the 5-HT3 serotonin receptor.

  1998cited by this paper
• Redistribution and Stabilization of Cell Surface Glutamate Receptors during Synapse Formation

  1997cited by this paper
• A general assay for antibody catalysis using acridone as a fluorescent tag.

  1996cited by this paper
• Characterization of a human 5‐hydroxytryptamine3 receptor type A (h5‐HT3R‐AS) subunit stably expressed in HEK 293 cells

  1996cited by this paper
• Immunological Characterization and Transmembrane Topology of 5‐Hydroxytryptamine3 Receptors by Functional Epitope Tagging

  1996cited by this paper
• Evidence that the atypical 5‐HT3 receptor ligand, [3H]‐BRL46470, labels additional 5‐HT3 binding sites compared to [3H]‐granisetron

  1995cited by this paper
• A pharmacological comparison of [3H]-granisetron binding sites in brain and peripheral tissues of the mouse

  1995cited by this paper
• The interaction of RS 25259‐197, a potent and selective antagonist, with 5‐HT3 receptors, in vitro

  1995cited by this paper
• Synthesis of a fluorescent steroid derivative with high affinities for the glucocorticoid and progesterone receptors.

  1994cited by this paper
• Nervous system distribution of the serotonin 5-HT3 receptor mRNA.

  1993cited by this paper
• Molecular Properties of 5‐Hydroxytryptamine3 Receptor‐Type Binding Sites Purified from NG1O8‐15 Cells

  1992cited by this paper
• [3H] GR67330, a very high affinity ligand for 5-HT3 receptors

  1990cited by this paper
• Characterization of 5-HT3 receptors in intact N1E-115 neuroblastoma cells.

  1990cited by this paper
• Subunit organization and structure of an acetylcholine receptor.

  1983cited by this paper

• The Concise Guide to PHARMACOLOGY 2023/24: Ion channels

  2023cites this paper
• Boron-containing compounds on neurons: Actions and potential applications for treating neurodegenerative diseases.

  2022cites this paper
• Lighting up the plasma membrane: Development and applications of fluorescent ligands for transmembrane proteins.

  2021cites this paper
• Autoradiographic labelling of 5-HT3 receptors in the hemi-parkinsonian rat brain.

  2021cites this paper
• Drug Discovery on Natural Products: From Ion Channels to nAChRs, from Nature to Libraries, from Analytics to Assays

  2019cites this paper
• A challenge finding P2X1 and P2X4 ligands.

  2019cites this paper
• Mapping the Orthosteric Binding Site of the Human 5-HT3 Receptor Using Photo-cross-linking Antagonists.

  2018cites this paper
• The binding orientation of epibatidine at α7 nACh receptors

  2017cites this paper
• Expression, Biochemistry, and Stabilization with Camel Antibodies of Membrane Proteins: Case Study of the Mouse 5-HT3 Receptor.

  2017cites this paper
• The muscarinic antagonists scopolamine and atropine are competitive antagonists at 5-HT3 receptors

  2016cites this paper
• Lighting up neuroscience.

  2015cites this paper