Neuronal and glial handling of glutamate and glutamine during hypoosmotic stress: a biochemical and quantitative immunocytochemical analysis using the rat cerebellum as a model.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Neuroscience

• Publication date

  1996-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0306-4522(96)00003-6PMID 9157320
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Distribution of glutamine-like immunoreactivity in the cerebellum of rat and baboon (Papio anubis) with reference to the issue of metabolic compartmentation

  2005cited by this paper
• Glutamate-like immunoreactivity revealed in rat olfactory bulb, hippocampus and cerebellum by monoclonal antibody and sensitive staining method

  2004cited by this paper
• Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87

  2004cited by this paper
• Simultaneous demonstration of multiple antigens by indirect immunofluorescence or immunogold staining

  2004cited by this paper
• Postembedding light- and electron microscopic immunocytochemistry of amino acids: description of a new model system allowing identical conditions for specificity testing and tissue processing

  2004cited by this paper
• Quantitative assessment of taurine-like immunoreactivity in different cell types and processes in rat cerebellum: an electronmicroscopic study based on a postembedding immunogold labelling procedure

  2004cited by this paper
• Colocalization of glutamate and glycine in bipolar cell terminals of the human retina

  2004cited by this paper
• Evidence for Glutamate as Neurotransmitter in Trigemino‐ and Spinothalamic Tract Terminals in the Nucleus Submedius of Cats

  1995cited by this paper
• Stimulation of calcium uptake in cultured astrocytes by hypoosmotic stress--effect of cyclic AMP.

  1994cited by this paper
• Effects of Ca(II) ions on Mn(II) dynamics in chick glia and rat astrocytes: Potential regulation of glutamine synthetase

  1994cited by this paper
• Taurine in Health and Disease

  1994cited by this paper
• Volume regulation in cultured neurons: pivotal role of taurine.

  1994cited by this paper
• Regulation of mammalian brain cell volume

  1994cited by this paper
• Kinetic, ESR, and trapping evidence for in vivo binding of Mn(II) to glutamine synthetase in brain cells

  1994cited by this paper
• Taurine as an organic osmolyte in the intact brain: immunocytochemical and biochemical studies.

  1994cited by this paper
• Light- and electronmicroscopic distribution of taurine, an organic osmolyte, in rat renal tubule cells.

  1994cited by this paper
• Regulation of mammalian brain cell volume.

  1994cited by this paper
• Organic osmolytes in acute hyponatremia.

  1993cited by this paper
• Contribution of organic and inorganic osmolytes to volume regulation in rat brain cells in culture

  1993cited by this paper
• Role of calcium in astrocyte volume regulation and in the release of ions and amino acids

  1993cited by this paper
• Neuronal-glial exchange of taurine during hypo-osmotic stress: a combined immunocytochemical and biochemical analysis in rat cerebellar cortex.

  1993cited by this paper
• Regulation of solute and water balance and cell volume in the central nervous system.

  1992cited by this paper
• Effect of pH on Glutamine Content Derived from Exogenous Glutamate in Astrocytes

  1992cited by this paper
• Role of taurine in neural cell volume regulation.

  1992cited by this paper
• Physiological actions of taurine.

  1992cited by this paper
• 1‐Aminocyclopentane‐trans‐1,3‐Dicarboxylic Acid Induces Glutamine Synthetase Activity in Cultured Astrocytes

  1992cited by this paper
• Metabolic compartmentation of glutamate and glutamine: morphological evidence obtained by quantitative immunocytochemistry in rat cerebellum.

  1992cited by this paper
• Elevation of Taurine in Hippocampal Extracellular Fluid and Cerebrospinal Fluid of Acutely Hypoosmotic Rats: Contribution by Influx from Blood?

  1991cited by this paper
• Hyponatremia causes large sustained reductions in brain content of multiple organic osmolytes in rats.

  1991cited by this paper
• Taurine: Functional neurochemistry, physiology, and cardiology: edited by Herminia Pasantes-Morales, David L. Martin, William Shain, and Rafael Martin del Rio. New York: Wiley, 1990, 498 pp. Price: $139.95

  1991cited by this paper
• Cellular and subcellular redistribution of glutamate-, glutamine- and taurine-like immunoreactivities during forebrain ischemia: a semiquantitative electron microscopic study in rat hippocampus.

  1991cited by this paper
• Cell volume regulation: a review of cerebral adaptive mechanisms and implications for clinical treatment of osmolal disturbances: II

  1991cited by this paper
• Study of brain electrolytes and organic osmolytes during correction of chronic hyponatremia. Implications for the pathogenesis of central pontine myelinolysis.

  1991cited by this paper
• Metabolism and role of glutamate in mammalian brain.

  1990cited by this paper
• Swelling-induced release of glutamate, aspartate, and taurine from astrocyte cultures

  1990cited by this paper
• Neuronal Glutamine Utilization: Glutamine/Glutamate Homeostasis in Synaptosomes

  1990cited by this paper
• MORFOREL, a computer program for two-dimensional analysis of micrographs of biological specimens, with emphasis on immunogold preparations.

  1990cited by this paper
• Neuronal discharge hypersynchrony and the intracranial water balance in relation to glutamic acid and taurine redistribution: migraine and epilepsy.

  1990cited by this paper
• Neuronal discharge hypersynchrony and the intracranial water balance in relation to glutamic acid and taurine redistribution: migraine and epilepsy.

  1990cited by this paper
• Neurologic manifestations of fluid and electrolyte disturbances.

  1989cited by this paper
• Postembedding immunogold labelling of fixed glutamate: an electron microscopic analysis of the relationship between gold particle density and antigen concentration.

  1989cited by this paper
• Effects of Microdialysis‐Perfusion with Anisoosmotic Media on Extracellular Amino Acids in the Rat Hippocampus and Skeletal Muscle

  1989cited by this paper
• myo-Inositol: A Newly Identified Nonnitrogenous Osmoregulatory Molecule in Mammalian Brain

  1989cited by this paper
• Cell volume regulation in the nervous system.

  1988cited by this paper
• Does taurine act as an osmoregulatory substance in the rat brain?

  1988cited by this paper
• Adaptation to chronic hypoosmolality in rats.

  1988cited by this paper
• A Possible Role for Taurine in Osmoregulation Within the Brain

  1988cited by this paper
• Adaptive decreases in amino acids (taurine in particular), creatine, and electrolytes prevent cerebral edema in chronically hyponatremic mice: Rapid correction (experimental model of central pontine myelinolysis) causes dehydration and shrinkage of brain

  1987cited by this paper
• Influence of Na+, K+, and Ca2+ on Glutamine Synthesis and Distribution in Rat Brain Cortex Slices: A Possible Linkage of Glutamine Synthetase with Cerebral Transport Processes and Energetics in the Astrocytes

  1987cited by this paper
• Biochemistry and physiology of brain ammonia.

  1987cited by this paper
• Volume regulatory loss of Na, Cl, and K from rat brain during acute hyponatremia.

  1987cited by this paper
• Excitatory Amino Acids

  1986cited by this paper
• Taurine Biological Actions and Clinical Perspectives

  1986cited by this paper
• Effect of Altered Blood Plasma Osmolalities on Regional Brain Amino Acid Concentrations and Focal Seizure Susceptibility in the Rat

  1986cited by this paper
• The osmoregulatory function of taurine and glutamic acid.

  1985cited by this paper
• Glutamate: A Neurotransmitter in Mammalian Brain

  1984cited by this paper
• Different populations of GABAergic neurons in the visual cortex and hippocampus of cat contain somatostatin- or cholecystokinin- immunoreactive material

  1984cited by this paper
• Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

  1984cited by this paper
• Brain and CSF water and ions during dilutional and isosmotic hyponatremia in the rat.

  1983cited by this paper
• Abnormalities of cell volume regulation and their functional consequences.

  1980cited by this paper
• Fine structural localization of glutamine synthetase in astrocytes of rat brain.

  1979cited by this paper
• Distribution of glutamine synthetase in the rat central nervous system.

  1979cited by this paper
• Glutamine synthetase: glial localization in brain

  1977cited by this paper
• NEUROLOGICAL MANIFESTATIONS AND MORBIDITY OF HYPONATREMIA: CORRELATION WITH BRAIN WATER AND ELECTROLYTES

  1976cited by this paper
• Brain edema.

  1975cited by this paper
• EFFECTS OF SALT AND WATER LOADING ON CARBOHYDRATE AND ENERGY METABOLISM AND LEVELS OF SELECTED AMINO ACIDS IN THE BRAINS OF YOUNG MICE 1

  1975cited by this paper
• Protective adaptation of brain to water intoxication.

  1973cited by this paper
• Cerebral water and electrolytes. An experimental model of inappropriate secretion of antidiuretic hormone.

  1972cited by this paper
• Factors that limit brain volume changes in response to acute and sustained hyper- and hyponatremia.

  1968cited by this paper
• Cerebral edema in water intoxication. I. Clinical and chemical observations.

  1968cited by this paper
• CHANGES IN THE BRAIN RESULTING FROM DEPLETION OF EXTRACELLULAR ELECTROLYTES

  1940cited by this paper

• A new experimental mouse model of water intoxication with sustained increased intracranial pressure and mild hyponatremia without side effects of antidiuretics

  2019cites this paper
• Advance Publication Experimental Animals

  2019cites this paper
• In vivo N-15 MRS study of glutamate metabolism in the rat brain.

  2017cites this paper
• The frequently used intraperitoneal hyponatraemia model induces hypovolaemic hyponatraemia with possible model‐dependent brain sodium loss

  2016cites this paper
• Disinhibition reduces extracellular glutamine and elevates extracellular glutamate in rat hippocampus in vivo.

  2015cites this paper
• Electrographic seizures are significantly reduced by in vivo inhibition of neuronal uptake of extracellular glutamine in rat hippocampus.

  2013cites this paper
• Nitrogen Metabolism In Vivo

  2012cites this paper
• Localization of brain endothelial luminal and abluminal transporters with immunogold electron microscopy

  2011cites this paper
• Chronic electrographic seizure reduces glutamine and elevates glutamate in the extracellular fluid of rat brain.

  2011cites this paper
• Hypo‐osmotic swelling modifies glutamate‐glutamine cycle in the cerebral cortex and in astrocyte cultures

  2011cites this paper
• Structural remodeling of gray matter astrocytes in the neonatal pig brain after hypoxia/ischemia

  2010cites this paper
• Real‐time passive volume responses of astrocytes to acute osmotic and ischemic stress in cortical slices and in vivo revealed by two‐photon microscopy

  2009cites this paper
• Acute Increase of the Glutamate–Glutamine Cycling in Discrete Brain Areas after Administration of a Single Dose of Amphetamine

  2008cites this paper
• Water entry into astrocytes during brain edema formation

  2008cites this paper
• Kinetics of glial glutamine efflux and the mechanism of neuronal uptake studied in vivo in mildly hyperammonemic rat brain

  2006cites this paper
• Changes In Blood Neurotransmitter And Steroid Levels During Evoked Vertigo

  2005cites this paper
• Suppression of glial glutamine release to the extracellular fluid studied in vivo by NMR and microdialysis in hyperammonemic rat brain

  2005cites this paper
• Water transport in the brain: role of cotransporters.

  2004cites this paper
• The neurobiology of glia in the context of water and ion homeostasis.

  2004cites this paper
• Impact of experimental acute hyponatremia on severe traumatic brain injury in rats: influences on injuries, permeability of blood-brain barrier, ultrastructural features, and aquaporin-4 expression.

  2002cites this paper
• Chapter 1 Biochemistry and anatomy of transmitter glutamate

  2000cites this paper
• PALIREL, a Computer Program for Analyzing Particle-to-Membrane Relations, with Emphasis on Electron Micrographs of Immunocytochemical Preparations and Gold Labeled Molecules

  1999cites this paper
• Modulation of AMPA receptor subunits GluR1 and GluR2/3 in the rat cerebellum in an experimental hepatic encephalopathy model.

  1997cites this paper
• Region‐selective glutamine synthetase expression in the rat central nervous system following portocaval anastomosis

  1997cites this paper
• Molecular organization of cerebellar glutamate synapses.

  1997cites this paper
• Glial Alkalinization Detected In Vivo by 1H‐15N Heteronuclear Multiple‐Quantum Coherence‐Transfer NMR in Severely Hyperammonemic Rat

  1997cites this paper
• Chapter 6 Molecular organization of cerebellar glutamate synapses

  1997cites this paper
• Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain

  1997cites this paper
• Basal expression and induction of glutamate decarboxylase GABA in excitatory granule cells of the rat and monkey hippocampal dentate gyrus

  1996cites this paper