Involvement of Mitogen-Activated Protein Kinase Pathways in Staphylococcus aureus Invasion of Normal Osteoblasts

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Infection and Immunity

• Publication date

  2001-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/IAI.69.9.5235-5242.2001PMID 11500391PMCID PMC98631
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Intracellular Staphylococcus aureus induces apoptosis in mouse osteoblasts.

  2000cited by this paper
• In vivo internalization of Staphylococcus aureus by embryonic chick osteoblasts.

  2000cited by this paper
• Staphylococcus aureus infection of mouse or human osteoblasts induces high levels of interleukin-6 and interleukin-12 production.

  1999cited by this paper
• Differential role for p38 mitogen-activated protein kinase in regulating CD40-induced gene expression in dendritic cells and B cells.

  1999cited by this paper
• Mechanisms of Staphylococcus aureus invasion of cultured osteoblasts.

  1999cited by this paper
• Mechanisms of Internalization ofStaphylococcus aureus by Cultured Human Osteoblasts

  1999influential reference
• Platelet-derived Growth Factor Induces Interleukin-6 Transcription in Osteoblasts through the Activator Protein-1 Complex and Activating Transcription Factor-2*

  1999cited by this paper
• Listeria monocytogenes Invasion of Epithelial Cells Requires the MEK-1/ERK-2 Mitogen-Activated Protein Kinase Pathway

  1998cited by this paper
• Effect of Staphylococcus aureus extracellular proteinaceous fraction in an isolated osteoclastic resorption assay

  1998cited by this paper
• Intracellular Staphylococcus aureusEscapes the Endosome and Induces Apoptosis in Epithelial Cells

  1998cited by this paper
• Tumor Necrosis Factor-α Induces Interleukin-6 Production and Integrin Ligand Expression by Distinct Transduction Pathways*

  1998cited by this paper
• Treatment of Osteomyelitis With a Biodegradable Antibiotic Implant

  1997cited by this paper
• Local expression of tumor necrosis factor alpha in an experimental model of acute osteomyelitis in rats

  1997cited by this paper
• Involvement of mitogen-activated protein kinase pathways in the nuclear responses and cytokine production induced by Salmonella typhimurium in cultured intestinal epithelial cells.

  1997cited by this paper
• Staphylococcus aureus invasion of bovine mammary epithelial cells.

  1996cited by this paper
• Molecular Cloning and Expression of the Gene for Elastin-binding Protein (ebpS) in Staphylococcus aureus*

  1996cited by this paper
• Isolation and culture of bone-forming cells (osteoblasts) from human bone.

  1996cited by this paper
• Selective interaction of JNK protein kinase isoforms with transcription factors.

  1996cited by this paper
• Characterization of the Structure and Function of a Novel MAP Kinase Kinase (MKK6) (*)

  1996cited by this paper
• MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

  1996cited by this paper
• Role of the accessory gene regulator (agr) in pathogenesis of staphylococcal osteomyelitis

  1995cited by this paper
• The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway.

  1995cited by this paper
• Surface‐associated proteins from Staphylococcus aureus demonstrate potent bone resorbing activity

  1995cited by this paper
• Transcription factor ATF2 regulation by the JNK signal transduction pathway

  1995cited by this paper
• ATF‐2 is preferentially activated by stress‐activated protein kinases to mediate c‐jun induction in response to genotoxic agents.

  1995cited by this paper
• Cloning, expression, and nucleotide sequence of a Staphylococcus aureus gene (fbpA) encoding a fibrinogen-binding protein

  1995cited by this paper
• Internalization of Staphylococcus aureus by cultured osteoblasts.

  1995cited by this paper
• Interleukin-6 enhances hypercalcemia and bone resorption mediated by parathyroid hormone-related protein in vivo.

  1995cited by this paper
• Mitogen and stress response pathways: MAP kinase cascades and phosphatase regulation in mammals and yeast.

  1995cited by this paper
• Molecular characterization of the clumping factor (fibrinogen receptor) of Staphylococcus aureus

  1994cited by this paper
• JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain.

  1994cited by this paper
• Cloning and characterization of a gene for a 19kDa fibrinogen‐binding protein from Staphylococcus aureus

  1994cited by this paper
• A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells.

  1994cited by this paper
• Medium pH modulates matrix, mineral, and energy metabolism in cultured chick bones and osteoblast-like cells.

  1994cited by this paper
• Listeria monocytogenes, an invasive bacterium, stimulates MAP kinase upon attachment to epithelial cells.

  1994influential reference
• The stress-activated protein kinase subfamily of c-Jun kinases

  1994cited by this paper
• Cloning and characterization of a gene for a 19 kDa fibrinogen-binding protein from Staphylococcus aureus.

  1994cited by this paper
• Signal transduction and invasion of epithelial cells by S. typhimurium.

  1993cited by this paper
• The mitogen-activated protein kinase signal transduction pathway.

  1993cited by this paper
• Identification of a Staphylococcus aureus extracellular matrix-binding protein with broad specificity

  1993cited by this paper
• Molecular characterization and expression of a gene encoding a Staphylococcus aureus collagen adhesin.

  1992cited by this paper
• Intracellular Localization of Staphylococcus aureus within Primary Cultured Mouse Kidney Cells

  1992cited by this paper
• Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid.

  1992cited by this paper
• MAP kinases: charting the regulatory pathways.

  1992cited by this paper
• Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases.

  1992cited by this paper
• Conspicuous Ingestion of Staphylococcus aureus Organisms by Murine Fibroblasts In Vitro

  1992cited by this paper
• Phosphorylation of c-jun mediated by MAP kinases

  1991cited by this paper
• ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF.

  1991cited by this paper
• Two different genes encode fibronectin binding proteins in Staphylococcus aureus. The complete nucleotide sequence and characterization of the second gene.

  1991cited by this paper
• Identification of the regulatory phosphorylation sites in pp42/mitogen‐activated protein kinase (MAP kinase).

  1991cited by this paper
• Effect of immune cytokines on bone.

  1989cited by this paper
• Pathobiology of infection in prosthetic devices.

  1988cited by this paper
• Cloning and expression of the gene for a fibronectin‐binding protein from Staphylococcus aureus.

  1987cited by this paper
• Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities.

  1986cited by this paper
• Diverse mitogenic agents induce rapid phosphorylation of a common set of cellular proteins at tyrosine in quiescent mammalian cells.

  1985cited by this paper
• Tyrosine phosphorylation of specific proteins after mitogen stimulation of chicken embryo fibroblasts

  1983cited by this paper
• Osteomyelitis: a review of clinical features, therapeutic considerations and unusual aspects.

  1970cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• Salmonella typhimurium

  year unknowncited by this paper

• Implant-Derived S. aureus Isolates Drive Strain-Specific Invasion Dynamics and Bioenergetic Alterations in Osteoblasts

  2025cites this paper
• Intracellular survival of Staphylococcus aureus in macrophages during osteomyelitis

  2025cites this paper
• Identification of interaction partners of outer inflammatory protein A: Computational and experimental insights into how Helicobacter pylori infects host cells

  2024cites this paper
• AuAg nanocomposites suppress biofilm-induced inflammation in human osteoblasts

  2023cites this paper
• High-Frequency Repetitive Magnetic Stimulation Activates Bactericidal Activity of Macrophages via Modulation of p62/Keap1/Nrf2 and p38 MAPK Pathways

  2023cites this paper
• Systemic IL-27 administration prevents abscess formation and osteolysis via local neutrophil recruitment and activation

  2022cites this paper
• Enhancement of Impaired MRSA‐Infected Fracture Healing by Combinatorial Antibiotics and Modulation of Sustained Inflammation

  2022cites this paper
• The role of Staphylococcus aureus small colony variants in intraosseous invasion and colonization in periprosthetic joint infection

  2022cites this paper
• Insight into the human pathodegradome of the V8 protease from Staphylococcus aureus

  2021cites this paper
• Combination of Kaempferol and Azithromycin attenuates Staphylococcus aureus induced osteomyelitis via anti-biofilm effect and inhibiting phosphorylation of ERK1/2 and SAPK.

  2021cites this paper
• Combination of kaempferol and azithromycin attenuates Staphylococcus aureus -induced osteomyelitis via anti-biofilm effects and by inhibiting the phosphorylation of ERK1/2 and SAPK

  2021influential citation
• Mechanisms of Antibiotic Failure During Staphylococcus aureus Osteomyelitis

  2021cites this paper
• Impact of the Host-Microbiome on Osteomyelitis Pathogenesis

  2021cites this paper
• Bone protein analysis via label-free quantitative proteomics in patients with periprosthetic joint infection.

  2021cites this paper
• Structure and functional analysis reveal an important regulated role of arginine kinase in Patinopecten yessoensis under low pH stress.

  2020cites this paper
• Identification of candidate genes affecting chronic subclinical mastitis in Norwegian Red cattle: combining genome-wide association study, topologically associated domains and pathway enrichment analysis.

  2019cites this paper
• Mechanisms of Immune Evasion and Bone Tissue Colonization That Make Staphylococcus aureus the Primary Pathogen in Osteomyelitis

  2019cites this paper
• Staphylococcal superantigen‐like proteins interact with human MAP kinase signaling protein ERK2

  2019cites this paper
• Evolving concepts in bone infection: redefining “biofilm”, “acute vs. chronic osteomyelitis”, “the immune proteome” and “local antibiotic therapy”

  2019cites this paper
• Host-Targeted Therapeutics against Multidrug Resistant Intracellular Staphylococcus aureus

  2019cites this paper
• Chronic Osteomyelitis, Biofilm, and Local Antibiosis

  2018cites this paper
• Current treatment of infected non-union after intramedullary nailing.

  2017cites this paper
• Sodium Octanoate Modulates the Innate Immune Response of Bovine Mammary Epithelial Cells through the TLR2/P38/JNK/ERK1/2 Pathway: Implications during Staphylococcus aureus Internalization

  2017cites this paper
• The activation of the TLR2/p38 pathway by sodium butyrate in bovine mammary epithelial cells is involved in the reduction of Staphylococcus aureus internalization.

  2015influential citation
• Coordinated Molecular Cross-Talk between Staphylococcus aureus, Endothelial Cells and Platelets in Bloodstream Infection

  2015cites this paper
• Dysregulation of the endothelium following Staphylococcus aureus infection.

  2015cites this paper
• Staphylococcus aureus vs. Osteoblast: Relationship and Consequences in Osteomyelitis

  2015cites this paper
• Involvement of Toll-Like Receptor 2 and Pro-Apoptotic Signaling Pathways in Bone Remodeling in Osteomyelitis

  2014cites this paper
• Intracellular proliferation of S. aureus in osteoblasts and effects of rifampicin and gentamicin on S. aureus intracellular proliferation and survival.

  2014cites this paper
• Endoscopic sinus surgery for treatment of kartagener syndrome: a case report.

  2013cites this paper
• Effect of Coadministration of Vancomycin and BMP-2 on Cocultured Staphylococcus aureus and W-20-17 Mouse Bone Marrow Stromal Cells In Vitro

  2012cites this paper
• Interactions of Staphylococci with Osteoblasts and Phagocytes in the Pathogenesis of Implant-Associated Osteomyelitis

  2012cites this paper
• Effect of co-administration of vancomycin and BMP-2 on co3 cultured Staphylococcus aureus and W-20-17 mouse bone marrow 4 stromal cells in vitro 5 6 7

  2012cites this paper
• Intracellular staphylococcus aureus: Live-in and let die

  2012influential citation
• Managing upper respiratory tract complications of primary ciliary dyskinesia in children

  2012cites this paper
• Interaction of Staphylococcus aureus with osteoblasts (Review).

  2012cites this paper
• High mobility group nucleosomal binding domain 2 protein protects bladder epithelial cells from Klebsiella pneumoniae invasion.

  2011cites this paper
• High-mobility group protein N2 (HMGN2) inhibited the internalization of Klebsiella pneumoniae into cultured bladder epithelial cells.

  2011cites this paper
• High-mobility group protein N 2 ( HMGN 2 ) inhibited the internalization of Klebsiella pneumoniae into cultured bladder epithelial cells

  2011cites this paper
• Attachment of Staphylococcus aureus is required for activation of nuclear factor kappa B in human osteoblasts.

  2010cites this paper
• Agenesis of paranasal sinuses and nasal nitric oxide in primary ciliary dyskinesia

  2010cites this paper
• Polymeric Immunoglobulin Receptor-mediated Invasion of Streptococcus pneumoniae into Host Cells Requires a Coordinate Signaling of SRC Family of Protein-tyrosine Kinases, ERK, and c-Jun N-terminal Kinase*

  2010cites this paper
• Endothelial Cell Factors Involved in Bartonella Bacilliformis Pathogenesis

  2009cites this paper
• RANK-L expression in Staphylococcus aureus-induced osteomyelitis, therapeutic intervention using nanotechnology and use of UV-killed bacteria as an osteoconductive coating for biomaterials

  2009cites this paper
• Epithelial Cell Gene Expression Induced by Intracellular Staphylococcus aureus

  2009cites this paper
• C-jun N-terminal kinase-mediated signaling is essential for Staphylococcus aureus-induced U937 apoptosis.

  2009cites this paper
• Staphylococcus aureus Induces Expression of Receptor Activator of NF-κB Ligand and Prostaglandin E2 in Infected Murine Osteoblasts

  2008cites this paper
• Internalization of Staphylococcus aureus by Bovine Endothelial Cells is Associated with the Activity State of NF‐κB and Modulated by the Pro‐inflammatory Cytokines TNF‐α and IL‐1β

  2008cites this paper
• Expression of activated ATF-2, CREB and c-Myc in rat colon transversum after whole-body γ-irradiation and its contribution to pathogenesis and biodosimetry

  2008cites this paper
• Expression of Receptor Activator of Nf- Induces Staphylococcus Aureus

  2008cites this paper
• Helenalin reduces Staphylococcus aureus infection in vitro and in vivo.

  2007cites this paper
• エピガロカテキンガレートはマウス骨芽細胞の黄色ブドウ球菌感染によるreceptor activator of NF-kB ligand発現を抑制する

  2007cites this paper
• Bacterial Induction of Early Response Genes and Activation of Proapoptotic Factors in Pleural Mesothelial Cells

  2007cites this paper
• Short communication Helenalin reduces Staphylococcus aureus infection in vitro and in vivo

  2007cites this paper
• Roles of mitogen-activated protein kinase pathways during Escherichia coli-induced apoptosis in U937 cells

  2007cites this paper
• Intracellular Staphylococcus aureus and antibiotic resistance: Implications for treatment of staphylococcal osteomyelitis

  2006cites this paper
• Invasion intracellulaire des cellules non-phagocytaires par Staphylococcus aureus

  2006cites this paper
• Mechanism and consequences of invasion of endothelial cells by Staphylococcus aureus

  2005cites this paper
• Porphyromonas gingivalis Induces Receptor Activator of NF-κB Ligand Expression in Osteoblasts through the Activator Protein 1 Pathway

  2004influential citation
• Intracellular Staphylococcus aureus. A mechanism for the indolence of osteomyelitis.

  2003cites this paper
• Infection by Streptococcus pyogenes Induces the Receptor Activator of NF-κB Ligand Expression in Mouse Osteoblastic Cells

  2003cites this paper
• A MECHANISM FOR THE INDOLENCE OF OSTEOMYELITIS

  2003cites this paper
• Staphylococcus aureus - induced tumor necrosis factor - related apoptosis - inducing ligand expression mediates apoptosis and caspase-8 activation in infected osteoblasts

  2003cites this paper
• Pseudomonas aeruginosa internalization by corneal epithelial cells involves MEK and ERK signal transduction proteins.

  2002cites this paper
• Effects of Staphylococcus aureus on human keratinocytes.

  2002cites this paper
• Factors influencing the internalization of Staphylococcus aureus and impacts on the course of infections in humans

  2001cites this paper
• Factors influencing the internalization of Staphylococcus aureus and impacts on the course of infections in humans.

  2001cites this paper