Subchronic (13‐week) inhalation toxicity study of formaldehyde in rats

No abstract is available for this paper.

• Publication year

  1987

• Venue

  Journal of Applied Toxicology

• Publication date

  1987-02-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1002/jat.2550070108PMID 3611596
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Formaldehyde and hepatotoxicity: a review.

  1984cited by this paper
• Pathology of the kidney in "toxic oil epidemic syndrome".

  1984cited by this paper
• Comments on "Formaldehyde and Hepatotoxicity" by Beall and Ulsamer.

  1984cited by this paper
• A 26-week inhalation toxicity study with formaldehyde in the monkey, rat, and hamster.

  1983cited by this paper
• Carcinogenicity of formaldehyde in rats and mice after long-term inhalation exposure.

  1983cited by this paper
• Nasal cavity deposition, histopathology, and cell proliferation after single or repeated formaldehyde exposures in B6C3F1 mice and F-344 rats.

  1983cited by this paper
• Inhalation toxicity of acetaldehyde in rats. I. Acute and subacute studies.

  1982cited by this paper
• Gaseous formaldehyde and hydrogen chloride induction of nasal cancer in the rat.

  1982cited by this paper
• Effect of single or repeated formaldehyde exposure on minute volume of B6C3F1 mice and F-344 rats.

  1981cited by this paper
• Induction of squamous cell carcinomas of the rat nasal cavity by inhalation exposure to formaldehyde vapor.

  1980cited by this paper
• An evaluation of the criterion "organ weight" under conditions of growth retardation.

  1973cited by this paper
• Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent.

  1968cited by this paper
• BIOCHEMICAL EFFECTS IN RATS FROM IRRITATING AIR CONTAMINANTS.

  1964cited by this paper
• The colorimetric estimation of formaldehyde by means of the Hantzsch reaction.

  1953cited by this paper
• A Review of the

  year unknowncited by this paper

• Pathogenesis of chemically induced nasal cavity tumors in rodents: contribution to adverse outcome pathway

  2023cites this paper
• Use of the MucilAir Airway Assay, a New Approach Methodology, for Evaluating the Safety and Inhalation Risk of Agrochemicals

  2021cites this paper
• A comprehensive review of mechanistic insights into formaldehyde-induced nasal cavity carcinogenicity.

  2021cites this paper
• ANNEX XV RESTRICTION REPORT PROPOSAL FOR A RESTRICTION SUBSTANCE NAME: Formaldehyde and formaldehyde releasers IUPAC NAME: Formaldehyde and formaldehyde releasers EC NUMBER: 200-001-8 CAS NUMBER: 50-00-0 CONTACT DETAILS OF THE DOSSIER SUBMITTER: European Chemicals Agency

  2019cites this paper
• Six years after the NRC review of EPA's Draft IRIS Toxicological Review of Formaldehyde: Regulatory implications of new science in evaluating formaldehyde leukemogenicity

  2017cites this paper
• Prototype e-cigarette and the capillary aerosol generator (CAG) comparison and qualification for use in subchronic inhalation exposure testing

  2016cites this paper
• Morphological and Histological Changes in Lungs and Thyroid Gland Due to Exposure of Formalin in Albino Rats

  2016cites this paper
• Gross and histomorphological effects of formaldehyde on brain and lungs of Swiss albino mice

  2016cites this paper
• HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR

  2014cites this paper
• ON the safety of the use of formaldehyde in nail hardeners

  2014cites this paper
• Morphometrical and histometrical changes of kidney in immature mice exposed to aspartame

  2013cites this paper
• "Smoking wet": respiratory failure related to smoking tainted marijuana cigarettes.

  2013cites this paper
• Nasal Passages of Göttingen Minipigs from the Neonatal Period to Young Adult

  2012cites this paper
• Scientific assessment of the use of sugars as cigarette tobacco ingredients: A review of published and other publicly available studies

  2012cites this paper
• Discriminatory power of standard toxicity assays used to evaluate ingredients added to cigarettes.

  2012cites this paper
• A novel application of the Margin of Exposure approach: segregation of tobacco smoke toxicants.

  2011cites this paper
• Identifying an indoor air exposure limit for formaldehyde considering both irritation and cancer hazards

  2011cites this paper
• Is exposure to formaldehyde in air causally associated with leukemia?—A hypothesis-based weight-of-evidence analysis

  2011cites this paper
• Scientific Basis for Swedish Occupational Standards XXXI

  2011cites this paper
• Final report on carcinogens background document for formaldehyde.

  2010cites this paper
• 8.16 – Aldehydes

  2010cites this paper
• Effects of formaldehyde inhalation on the junctional proteins of nasal respiratory mucosa of rats.

  2009cites this paper
• Can Formaldehyde Exposure Induce Histopathologic and Morphometric Changes on Rat Kidney

  2009cites this paper
• Effects of postnatal formaldehyde exposure on pyramidal cell number, volume of cell layer in hippocampus and hemisphere in the rat: a stereological study.

  2007cites this paper
• Formaldehyde as a Potential Human Leukemogen: An Assessment of Biological Plausibility

  2006cites this paper
• Local effects in the respiratory tract: relevance of subjectively measured irritation for setting occupational exposure limits

  2006cites this paper
• Effects of formaldehyde exposure on granule cell number and volume of dentate gyrus: a histopathological and stereological study.

  2006cites this paper
• Inhaled formaldehyde: evaluation of sensory irritation in relation to carcinogenicity.

  2006cites this paper
• HISTOPATHOLOGIC CHANGES OF RAT LIVER FOLLOWING FORMALDEHYDE EXPOSURE

  2006cites this paper
• The changes of Zinc, Copper, and Iron levels in lung tissue after formaldehyde inhalation during the early postnatal period of Rats

  2005cites this paper
• Risk assessment of formaldehyde for the general population in Japan.

  2005cites this paper
• Laryngeal, laryngotracheal, and tracheal masses in cats: 27 cases (1998-2003).

  2005cites this paper
• Effects of Inhaled Toxicants on the Nose and Nasal Function

  2005cites this paper
• Comments on 'DNA—protein crosslinks, a biomarker of exposure to formaldehyde—in vitro and in vivo studies' by Shaham et al

  2005cites this paper
• A review and meta-analysis of formaldehyde exposure and leukemia.

  2004cites this paper
• Differences in source emission rates of volatile organic compounds in inner-city residences of New York City and Los Angeles

  2004cites this paper
• The implausibility of leukemia induction by formaldehyde: a critical review of the biological evidence on distant-site toxicity.

  2004cites this paper
• DNA–protein crosslinks and p53 protein expression in relation to occupational exposure to formaldehyde

  2003cites this paper
• Annual review of cosmetic ingredient safety assessments-2004/2005.

  2003cites this paper
• A study on the effect of inhalative formaldehyde exposure on water labyrinth test performance in rats.

  2003cites this paper
• A study on specific behavioral effects of formaldehyde in the rat

  2003cites this paper
• PCR tools for the differential diagnosis of Taenia saginata and Taenia solium taeniasis/cysticercosis from different geographical locations.

  2002cites this paper
• Toxicity Evaluation of Formaldehyde and Its Risk Assessment for Drinking Water Via Oral and Inhalation Exposure.

  2001cites this paper
• PRIORITY SUBSTANCES LIST ASSESSMENT REPORT

  2001cites this paper
• The Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals and The Dutch Expert Committee on Occupational Standards 127. Hydrogen sulphide

  2001cites this paper
• Health Risks Associated with Inhaled Nasal Toxicants

  2001cites this paper
• Effects of glutaraldehyde in a 2-year inhalation study in rats and mice.

  2000cites this paper
• Issues in applying statistical design of experiments, with special reference to toxicology of mixtures

  2000cites this paper
• Comparison of Fresh and Room-Aged Cigarette Sidestream Smoke in a Subchronic Inhalation Study on Rats

  1998cites this paper
• Subacute toxicity of a mixture of nine chemicals in rats: detecting interactive effects with a fractionated two-level factorial design.

  1997cites this paper
• DNA-Protein Crosslinks and Sister Chromatid Exchanges as Biomarkers of Exposure to Formaldehyde.

  1997cites this paper
• Subacute Toxicity of a Mixture of Nine Chemicals in Rats: Detecting Interactive Effects with a Fractionated Two-Level Factorial Design

  1997cites this paper
• Results of a 28-month chronic inhalation toxicity study of formaldehyde in male Fisher-344 rats.

  1997cites this paper
• Formaldehyde mechanistic data and risk assessment: endogenous protection from DNA adduct formation.

  1996cites this paper
• Comments on 'DNA-protein crosslinks, a biomarker of exposure to formaldehyde--in vitro and in vivo studies' by Shaham et al.

  1996cites this paper
• A parallelogram approach for safety evaluation of ingested acetaldehyde.

  1996cites this paper
• IARC Monographs on the Evaluation of Carcinogenic Risks to Humans

  1995cites this paper
• PATHOBIOLOGICAL FEATURES OF RESPIRATORY LESIONS IN RATS INHALING METHANOL-FUELED ENGINE EXHAUST-RECOVERY AND 12-WEEK SUBCHRONIC TOXICITY STUDIES-

  1995cites this paper
• Risk assessment and biological mechanisms: lessons learned, future opportunities.

  1995cites this paper
• DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde.

  1994cites this paper
• HISTOPATHOLOGICAL AND ELECTRON MICROSCOPICAL CHARACTERISTICS OF RESPIRATORY LESIONS IN RATS INHALING METHANOL-FUELED ENGINE EXHAUST FOR 28 DAYS

  1994cites this paper
• Pulmonary cytochrome P450 in rats exposed to formaldehyde vapor.

  1993cites this paper
• Cell proliferation in the respiratory tract of the rat after acute inhalation of formaldehyde or acrolein

  1993cites this paper
• Toxicity to rats of methanol-fueled engine exhaust inhaled continuously for 28 days.

  1992cites this paper
• Stimulation to the Trigeminal Afferent Nerve of the Nose by Formaldehyde, Acrolein, and Acetaldehyde Gases

  1991cites this paper
• Formaldehyde toxicity--new understanding.

  1990cites this paper
• Proliferative responses of rat nasal epithelia to ozone.

  1990cites this paper
• Biotransformation enzymes in the rodent nasal mucosa: the value of a histochemical approach.

  1990cites this paper
• Interactive effects of ozone and formaldehyde on the nasal respiratory lining epithelium in rats.

  1990cites this paper
• Pathology and Cell Proliferation Induced by Intra-nasal Instillation of Aldehydes in the Rat: Comparison of Glutaraldehyde and Formaldehyde

  1990cites this paper
• Inhalation Toxicity and Carcinogenicity of Formaldehyde in Animals: Significance for Assessment of Human Health Risk

  1989cites this paper
• Nasal tumours in rats after severe injury to the nasal mucosa and prolonged exposure to 10 ppm formaldehyde

  1989cites this paper
• Subchronic (13-week) inhalation toxicity study of formaldehyde in male rats: 8-hour intermittent versus 8-hour continuous exposures.

  1989cites this paper
• Nasal tumours in rats after short-term exposure to a cytotoxic concentration of formaldehyde.

  1988cites this paper
• One‐year inhalation toxicity study of formaldehyde in male rats with a damaged or undamaged nasal mucosa

  1988cites this paper
• Cytotoxic and adaptive effects in rat nasal epithelium after 3-day and 13-week exposure to low concentrations of formaldehyde vapour.

  1988cites this paper
• Concise International Chemical Assessment Document 49

  year unknowncites this paper