DNMT3A mutations are rare in childhood acute myeloid leukemia

F. Thol,M. Heuser,F. Damm,J. Klusmann,Katarina Reinhardt,D. Reinhardt

Published 2011 in Haematologica

ABSTRACT

Childhood acute myeloid leukemia (AML) is a complex disease of the hematopoietic stem cell. Overall survival is relatively low with an overall survival rate of 50–70%. Besides cytogenetic changes and response to induction therapy, molecular aberrations are important prognostic markers that can

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