1,25-Dihydroxyvitamin D3 and TPA activate phospholipase D in Caco-2 cells: role of PKC-α.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  American Journal of Physiology - Gastrointestinal and Liver Physiology

• Publication date

  1999-04-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1152/ajpgi.1999.276.4.G993PMID 10198344
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• 1,25-Dihydroxyvitamin D3 but not TPA activates PLD in Caco-2 cells via pp60c- src and RhoA.

  1999cited by this paper
• Characterization of a Rat Brain Phospholipase D Isozyme*

  1998cited by this paper
• Calcitriol transmembrane signalling: regulation of rat muscle phospholipase D activity.

  1998cited by this paper
• Decreased PKC-alpha expression increases cellular proliferation, decreases differentiation, and enhances the transformed phenotype of CaCo-2 cells.

  1998cited by this paper
• Protein kinase C alpha modulates growth and differentiation in Caco-2 cells.

  1998cited by this paper
• Protein kinase C α modulates growth and differentiation in Caco-2 cells

  1998cited by this paper
• Decreased PKC-α Expression Increases Cellular Proliferation, Decreases Differentiation, and Enhances the Transformed Phenotype of CaCo-2 Cells

  1998cited by this paper
• New Developments in Phospholipase D*

  1997influential reference
• Implication of Ca2+‐Dependent Protein Tyrosine Phosphorylation in Carbachol‐Induced Phospholipase D Activation in Rat Pheochromocytoma PC12 Cells

  1997cited by this paper
• Implication of Ca(2+)-dependent protein tyrosine phosphorylation in carbachol-induced phospholipase D activation in rat pheochromocytoma PC12 cells.

  1997cited by this paper
• Reconstitution of α2D-Adrenergic Receptor Coupling to Phospholipase D in a PC12 Cell Lysate*

  1997cited by this paper
• 1,25 D 3 Stimulates Phospholipase C- (cid:103) in Rat Colonocytes: Role of c-Src in PLC- (cid:103) Activation

  1997cited by this paper
• Phospholipase D: enzymology, mechanisms of regulation, and function.

  1997cited by this paper
• Characterization of Two Alternately Spliced Forms of Phospholipase D1

  1997cited by this paper
• 1,25 dihydroxyvitamin D3 stimulates phospholipase C-gamma in rat colonocytes: role of c-Src in PLC-gamma activation.

  1997cited by this paper
• Epithelial cell folate depletion occurs in neoplastic but not adjacent normal colon mucosa.

  1997cited by this paper
• Regulation of Membrane-bound Phospholipase D by Protein Kinase C in HL60 Cells

  1996cited by this paper
• Activation of phospholipase D by ras proteins is independent of protein kinase C

  1996cited by this paper
• 1,25(OH)2-vitamin D3 stimulation of phospholipases C and D in muscle cells involves extracellular calcium and a pertussis-sensitive G protein.

  1996cited by this paper
• Regulation of Phospholipase D by Protein Kinase C Is Synergistic with ADP-ribosylation Factor and Independent of Protein Kinase Activity (*)

  1996cited by this paper
• Role of PLA2, PLC, and PLD in bradykinin-induced release of arachidonic acid in MDCK cells.

  1996influential reference
• Regulation of phospholipase D by protein kinase C.

  1996cited by this paper
• Hepatocellular protein kinase C activation by bile acids: implications for regulation of cholesterol 7 alpha-hydroxylase.

  1996cited by this paper
• Antigen-mediated phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells: possible involvement of calcium/calmodulin.

  1995cited by this paper
• 1,25-Dihydroxyvitamin D3 and 12-O-tetradecanoyl phorbol 13-acetate cause differential activation of Ca(2+)-dependent and Ca(2+)-independent isoforms of protein kinase C in rat colonocytes.

  1995cited by this paper
• Implication of protein kinase C alpha in PAF-stimulated phospholipase D activation in Chinese hamster ovary (CHO) cells expressing PAF receptor.

  1995cited by this paper
• 1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, a noncalcemic analogue of 1 alpha,25-dihydroxyvitamin D3, inhibits azoxymethane-induced colonic tumorigenesis.

  1995cited by this paper
• Differential regulation of phospholipase D and phospholipase C by protein kinase C-beta and -delta in liver macrophages.

  1995cited by this paper
• Regulation of Phospholipase D by Protein Kinase C in Human Neutrophils

  1995cited by this paper
• Evidence That the Bradykinin-induced Activation of Phospholipase D and of the Mitogen-activated Protein Kinase Cascade Involve Different Protein Kinase C Isoforms (*)

  1995cited by this paper
• Evidence That Ceramide Selectively Inhibits Protein Kinase C-α Translocation and Modulates Bradykinin Activation of Phospholipase D (*)

  1995cited by this paper
• Lysophosphatidic Acid, a Multifunctional Phospholipid Messenger (*)

  1995cited by this paper
• Synthesis of bisindolylmaleimide macrocycles

  1995cited by this paper
• 1α,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol, a Noncalcemic Analogue of 1α,25-Dihydroxyvitamin D3, Inhibits Azoxymethane-induced Colonic Tumorigenesis

  1995cited by this paper
• Protein kinase C alpha mediates phospholipase D activation by nucleotides and phorbol ester in Madin-Darby canine kidney cells. Stimulation of phospholipase D is independent of activation of polyphosphoinositide-specific phospholipase C and phospholipase A2.

  1994influential reference
• Activation and desensitization of phospholipase D in intact rat hepatocytes.

  1994cited by this paper
• Effects of 1,25-dihydroxyvitamin D3 on proliferation and differentiation of Caco-2 cells.

  1994cited by this paper
• Phospholipase-D activation can be negatively regulated through the action of protein kinase C.

  1994cited by this paper
• 1,25(OH)2 vitamin D3 activates PKC-alpha in Caco-2 cells: a mechanism to limit secosteroid-induced rise in [Ca2+]i.

  1994cited by this paper
• v-Src activates a unique phospholipase D activity that can be distinguished from the phospholipase D activity activated by phorbol esters.

  1993cited by this paper
• Extracellular ATP and UTP activation of phospholipase D is mediated by protein kinase C‐ε in rat renal mesangial cells

  1993cited by this paper
• Up-regulation of phospholipase D activity induced by overexpression of protein kinase C-alpha. Studies in intact Swiss/3T3 cells and in detergent-solubilized membranes in vitro.

  1993cited by this paper
• Phospholipase D and cell signaling.

  1993influential reference
• Agonist-induced activation of phospholipase D in bovine pulmonary artery endothelial cells: regulation by protein kinase C and calcium.

  1993cited by this paper
• Characterization of the 1,25-dihydroxycholecalciferol-stimulated calcium influx pathway in CaCo-2 cells

  1993cited by this paper
• Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

  1993cited by this paper
• Extracellular ATP and UTP activation of phospholipase D is mediated by protein kinase C-epsilon in rat renal mesangial cells.

  1993cited by this paper
• Activation of phospholipase D by protein kinase C. Evidence for a phosphorylation-independent mechanism.

  1992cited by this paper
• Effect of vitamin D status on the rapid actions of 1,25-dihydroxycholecalciferol in rat colonic membranes.

  1992cited by this paper
• Differential regulation of phosphoinositide and phosphatidylcholine hydrolysis by protein kinase C-beta 1 overexpression. Effects on stimulation by alpha-thrombin, guanosine 5'-O-(thiotriphosphate), and calcium.

  1992influential reference
• Phospholipases C and D in mitogenic signal transduction.

  1992cited by this paper
• Calcium rather than protein kinase C is the major factor to activate phospholipase D in FMLP-stimulated rabbit peritoneal neutrophils. Possible involvement of calmodulin/myosin L chain kinase pathway.

  1992cited by this paper
• 1,25-dihydroxyvitamin D3 inhibits Na(+)-H+ exchange by stimulating membrane phosphoinositide turnover and increasing cytosolic calcium in CaCo-2 cells.

  1992cited by this paper
• A protective role of 1,25-dihydroxyvitamin D3 in chemically induced rat colon carcinogenesis.

  1992cited by this paper
• Phosphatidylcholine-specific phospholipase D-derived 1,2-diacylglycerol does not initiate protein kinase C activation in the RBL 2H3 mast-cell line.

  1992cited by this paper
• Activation of the PKC‐isotypes α, β1, γ, δ, and ε by phorbol esters of different biological activities

  1991cited by this paper
• Activation of the PKC-isotypes alpha, beta 1, gamma, delta and epsilon by phorbol esters of different biological activities.

  1991cited by this paper
• The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.

  1991cited by this paper
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  1991influential reference
• Dietary calcium and vitamin D modulate 1,2-dimethylhydrazine-induced colonic carcinogenesis in the rat.

  1991cited by this paper
• v-Src increases diacylglycerol levels via a type D phospholipase-mediated hydrolysis of phosphatidylcholine

  1991cited by this paper
• Sequence of human protein kinase C alpha.

  1990cited by this paper
• 1,25(OH)2 vitamin D3 stimulates membrane phosphoinositide turnover, activates protein kinase C, and increases cytosolic calcium in rat colonic epithelium.

  1990cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1989influential reference
• Phosphatidylcholine hydrolysis by phospholipase D determines phosphatidate and diglyceride levels in chemotactic peptide-stimulated human neutrophils. Involvement of phosphatidate phosphohydrolase in signal transduction.

  1989cited by this paper
• Inhibition of dietary fat-promoted colon carcinogenesis in rats by supplemental calcium or vitamin D3.

  1988cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper
• A rapid, sensitive, and specific method for the determination of protein in dilute solution.

  1973cited by this paper

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  2009cites this paper
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  2007cites this paper
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  2007cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
• Molecular Regulation of Calcium Metabolism

  2006cites this paper
• Regulation of butyrate uptake in Caco-2 cells by phorbol 12-myristate 13-acetate.

  2004influential citation
• Nongenomic steroid action: controversies, questions, and answers.

  2003cites this paper
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  2003cites this paper
• 1,25-Dihydroxyvitamin D3 selectively translocates PKCalpha to nuclei in ROS 17/2.8 cells.

  2002cites this paper
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  2001cites this paper
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  2001cites this paper
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  2001cites this paper
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