Detection of UGT1A10 polymorphisms and their association with orolaryngeal carcinoma risk

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Cancer

• Publication date

  2003-08-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/cncr.11587PMID 12910533
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  2000influential reference
• An Allele-Specific Polymerase Chain Reaction Method for the Determination of the D85Y Polymorphism in the Human UDPGlucuronosyltransferase 2B15 Gene in a Case-Control Study of Prostate Cancer

  2000cited by this paper
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  2000cited by this paper
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  2000cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications.

  1997influential reference
• The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

  1997influential reference
• Identification of a Rat Oltipraz-inducible UDP-glucuronosyltransferase (UGT1A7) with Activity Towards Benzo(a)pyrene-7,8-dihydrodiol*

  1997cited by this paper
• Gene structure at the human UGT1 locus creates diversity in isozyme structure, substrate specificity, and regulation.

  1995cited by this paper
• The glucuronidation of hydroxylated metabolites of benzo[a]pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases.

  1993cited by this paper
• UDP-glucuronosyltransferases: a family of detoxifying enzymes.

  1990cited by this paper
• Lung cancer risk associated with cigar and pipe smoking

  1986cited by this paper

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  2023cites this paper
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  2019cites this paper
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  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017influential citation
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  2016cites this paper
• Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk

  2016influential citation
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  2016cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2013cites this paper
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  2012cites this paper
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  2012influential citation
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  2012cites this paper
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  2012cites this paper
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  2011influential citation
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  2011cites this paper
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  2008cites this paper
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