Epitope-Dependent Effect of Anti-Murine TIM-1 Monoclonal Antibodies on T Cell Activity and Lung Immune Responses

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Immunology

• Publication date

  2007-02-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.178.4.2249PMID 17277130
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evidence for the increase in asthma worldwide.

  2007cited by this paper
• T Cell, Ig Domain, Mucin Domain-2 Gene-Deficient Mice Reveal a Novel Mechanism for the Regulation of Th2 Immune Responses and Airway Inflammation1

  2006cited by this paper
• Viral-Induced T Helper Type 1 Responses Enhance Allergic Disease by Effects on Lung Dendritic Cells

  2005cited by this paper
• An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children.

  2005cited by this paper
• TIM-4 is the ligand for TIM-1, and the TIM-1–TIM-4 interaction regulates T cell proliferation

  2005cited by this paper
• Anti-T-cell Ig and mucin domain-containing protein 1 antibody decreases TH2 airway inflammation in a mouse model of asthma.

  2005cited by this paper
• T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation.

  2005cited by this paper
• Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population.

  2005cited by this paper
• TIM-1 induces T cell activation and inhibits the development of peripheral tolerance

  2005cited by this paper
• The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

  2005influential reference
• Th2-specific chromatin remodeling and enhancer activity in the Th2 cytokine locus control region.

  2004cited by this paper
• Murine models of asthma

  2003cited by this paper
• Hepatitis A virus link to atopic disease

  2003cited by this paper
• Asthma: an epidemic of dysregulated immunity

  2002cited by this paper
• Shedding of Kidney Injury Molecule-1, a Putative Adhesion Protein Involved in Renal Regeneration*

  2002cited by this paper
• Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2

  2002influential reference
• Cytokine therapeutics for asthma: an appraisal of current evidence and future prospects.

  2001cited by this paper
• Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family

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• Pathophysiology of asthma.

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• Antigen-induced airway hyperresponsiveness, pulmonary eosinophilia, and chemokine expression in B cell-deficient mice.

  1999cited by this paper
• Kidney Injury Molecule-1 (KIM-1), a Putative Epithelial Cell Adhesion Molecule Containing a Novel Immunoglobulin Domain, Is Up-regulated in Renal Cells after Injury*

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• Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis a virus

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• The Inverse Association Between Tuberculin Responses and Atopic Disorder

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• Variation in virion phosphatidylserine content drives differential GAS6 binding among closely related flaviviruses

  2025cites this paper
• Structural basis for T cell immunoglobulin and mucin protein 3 and Toxascaris leonina galectin complex.

  2024cites this paper
• Role of TIM-1 in the development and treatment of tumours

  2024cites this paper
• The ability of human TIM1 to bind phosphatidylethanolamine enhances viral uptake and efferocytosis compared to rhesus and mouse orthologs

  2024cites this paper
• The ability of human TIM1 to bind phosphatidylethanolamine enhances viral uptake and efferocytosis compared to rhesus and mouse orthologs

  2024cites this paper
• Sensing Dying Cells in Health and Disease

  2024cites this paper
• Tim-1 Deficiency Aggravates High-Fat Diet-Induced Steatohepatitis in Mice

  2021cites this paper
• Immunosuppressive Mechanisms of Regulatory B Cells

  2021cites this paper
• Novel Roles of the Tim Family in Immune Regulation and Autoimmune Diseases

  2021cites this paper
• Mapping and functional characterization of murine kidney injury molecule-1 proteolytic cleavage site

  2020cites this paper
• Diagnostic role of kidney injury molecule-1 in renal cell carcinoma

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• Mapping and functional characterization of proteolytic cleavage of murine kidney injury molecule-1

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• Costimulation Blockade in Transplantation.

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• Tryptase and TIM-1 double-positive mast cells in different stages of human chronic periodontitis.

  2018cites this paper
• Diverse roles of TIM4 in immune activation: implications for alloimmunity

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• Modulating T Cell costimulation to prevent renal allograft rejection in nonhuman primates

  2017cites this paper
• Immuno-modulatory mechanism of T cell immunoglobulin mucin-1 antibody in experimental colitis induced by dextran sulfate sodium

  2017cites this paper
• Restriction of HIV by Tim-family proteins and antagonism by NEF

  2016cites this paper
• Immune Regulation and Antitumor Effect of TIM-1

  2016cites this paper
• Regulation of mast cell function by TIM-1 and TIM-3 signaling

  2016influential citation
• Essential Roles of TIM-1 and TIM-4 Homologs in Adaptive Humoral Immunity in a Zebrafish Model

  2016cites this paper
• Functional annotation of the T‐cell immunoglobulin mucin family in birds

  2016cites this paper
• Mast cell activation is enhanced by Tim1:Tim4 interaction but not by Tim-1 antibodies

  2016cites this paper
• Modulatory effects of GluN1 autoantibodies on brain function

  2015cites this paper
• Crystal structures of human TIM members: Ebolavirus entry-enhancing receptors

  2015cites this paper
• Distinct Trafficking of Cell Surface and Endosomal TIM‐1 to the Immune Synapse

  2015influential citation
• Protective Association of TIM1−1454G>A Polymorphism with Asthma in a North Indian Population

  2015cites this paper
• The role of TIM-1 in enveloped virus entry

  2014cites this paper
• Soluble T cell immunoglobulin and mucin domain (TIM)-1 and -4 generated by A Disintegrin And Metalloprotease (ADAM)-10 and -17 bind to phosphatidylserine.

  2014cites this paper
• Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4

  2014cites this paper
• Phosphatidylserine receptors: Enhancers of enveloped virus entry and infection

  2014cites this paper
• Expression and polymorphisms of T cell immunoglobulin domain and mucin domain protein-1 in thymoma with or without myasthenia gravis

  2014cites this paper
• TIM-1 glycoprotein binds the adhesion receptor P-selectin and mediates T cell trafficking during inflammation and autoimmunity.

  2014influential citation
• A bioinformatics approach identifies signal transducer and activator of transcription-3 and checkpoint kinase 1 as upstream regulators of kidney injury molecule-1 after kidney injury.

  2014cites this paper
• Regulation of T cell trafficking by the T cell immunoglobulin and mucin domain 1 glycoprotein.

  2014cites this paper
• Blocking monoclonal antibodies of TIM proteins as orchestrators of anti-tumor immune response

  2014cites this paper
• Molekulare Grundlagen der proteolytischen Spaltung von Tim-1 und Tim-4 durch ADAM-Proteasen.

  2014cites this paper
• Tim family of molecules in the chicken – important differences from mammals

  2014influential citation
• Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis.

  2013cites this paper
• and Effector Phases of Murine Arthritis TIM-4 Has Dual Function in the Induction

  2013cites this paper
• TIM-4 Has Dual Function in the Induction and Effector Phases of Murine Arthritis

  2013cites this paper
• Activated Neutrophils Mediate KIM-1 Shedding and Renal Remodelling

  2013cites this paper
• The T-cell immunoglobulin and mucin domain (Tim) gene family in asthma, allergy, and autoimmunity.

  2013cites this paper
• Targeting TIM‐1 on CD4 T Cells Depresses Macrophage Activation and Overcomes Ischemia‐Reperfusion Injury in Mouse Orthotopic Liver Transplantation

  2013cites this paper
• The role of TIM-containing molecules in airway disease and their potential as therapeutic targets

  2012cites this paper
• Murine Tim-1 is excluded from the immunological synapse.

  2012cites this paper
• Role of Tim-1 in immune responses

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  2012influential citation
• Murine Tim-1 is excluded from the immunological synapse

  2012cites this paper
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• Fyn binds to and phosphorylates T cell immunoglobulin and mucin domain-1 (Tim-1).

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  2011cites this paper
• The Emerging Role of the TIM Molecules in Transplantation

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• Novel roles for TIM-1 in immunity and infection.

  2011cites this paper
• Something against TIM-1 in asthma

  2010cites this paper
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  2010cites this paper
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• T Cell/Transmembrane, Ig, and Mucin-3 Allelic Variants Differentially Recognize Phosphatidylserine and Mediate Phagocytosis of Apoptotic Cells

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• The TIM family of cosignaling receptors: emerging targets for the regulation of autoimmune disease and transplantation tolerance.

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