Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Medicinal Chemistry

• Publication date

  2001-07-24

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/JM010072GPMID 11495594
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999cited by this paper
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  1995cited by this paper
• Mitomycin C: a prototype bioreductive agent.

  1994cited by this paper
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  1994cited by this paper
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  1993cited by this paper
• Isolation and structure of an intrastrand cross-link adduct of mitomycin C and DNA.

  1992cited by this paper
• Reactions of glutathione and glutathione radicals with benzoquinones.

  1992cited by this paper
• Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin.

  1992cited by this paper
• Reductive alkylation of DNA by mitomycin A, a mitomycin with high redox potential.

  1991cited by this paper
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  1991cited by this paper
• Recognition between mitomycin C and specific DNA sequences for cross-link formation.

  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1989cited by this paper
• Structure-activity comparison of mitomycin C and mitomycin A analogues (review).

  1989cited by this paper
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  1988cited by this paper
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  1988cited by this paper
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  1987cited by this paper
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  1987cited by this paper
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  1986cited by this paper
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  1986cited by this paper
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  1981cited by this paper
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