A Noncanonical Binding Site in the EVH1 Domain of Vasodilator-Stimulated Phosphoprotein Regulates Its Interactions with the Proline Rich Region of Zyxin.

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Biochemistry

• Publication date

  2017-08-23

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/acs.biochem.7b00618PMID 28783324PMCID PMC5724578
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Two-Dimensional NMR Lineshape Analysis

  2016cited by this paper
• Neighboring phosphoSer‐Pro motifs in the undefined domain of IRAK1 impart bivalent advantage for Pin1 binding

  2016cited by this paper
• Isomerase-catalyzed binding of interleukin-1 receptor-associated kinase 1 to the EVH1 domain of vasodilator-stimulated phosphoprotein.

  2014cited by this paper
• LIM Domains Target Actin Regulators Paxillin and Zyxin to Sites of Stress Fiber Strain

  2013cited by this paper
• Stretch-induced actin remodeling requires targeting of zyxin to stress fibers and recruitment of actin regulators

  2012cited by this paper
• Abl-1-bridged tyrosine phosphorylation of VASP by Abelson kinase impairs association of VASP to focal adhesions and regulates leukaemic cell adhesion.

  2012cited by this paper
• Zyxin phosphorylation at serine 142 modulates the zyxin head-tail interaction to alter cell-cell adhesion.

  2011cited by this paper
• Molecular mechanism of Ena/VASP-mediated actin-filament elongation

  2011cited by this paper
• A zyxin-mediated mechanism for actin stress fiber maintenance and repair.

  2010cited by this paper
• Ena/VASP: towards resolving a pointed controversy at the barbed end

  2009cited by this paper
• A zyxin head-tail interaction regulates zyxin-VASP complex formation.

  2009cited by this paper
• Clustering of VASP actively drives processive, WH2 domain‐mediated actin filament elongation

  2008cited by this paper
• Multiple WASP-interacting Protein Recognition Motifs Are Required for a Functional Interaction with N-WASP*

  2007cited by this paper
• On the benefit of bivalency in peptide ligand/pin1 interactions.

  2007cited by this paper
• Akt phosphorylation of zyxin mediates its interaction with acinus-S and prevents acinus-triggered chromatin condensation

  2007cited by this paper
• Migfilin Interacts with Vasodilator-stimulated Phosphoprotein (VASP) and Regulates VASP Localization to Cell-Matrix Adhesions and Migration*

  2006cited by this paper
• Ena/VASP Proteins Enhance Actin Polymerization in the Presence of Barbed End Capping Proteins*[boxs]

  2005cited by this paper
• Myosin X transports Mena/VASP to the tip of filopodia.

  2004cited by this paper
• Lamellipodial versus filopodial mode of the actin nanomachinery: pivotal role of the filament barbed end.

  2004cited by this paper
• The VASP tetramerization domain is a right-handed coiled coil based on a 15-residue repeat.

  2004cited by this paper
• Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1.

  2004cited by this paper
• Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation.

  2003cited by this paper
• Ena/VASP proteins: regulators of the actin cytoskeleton and cell migration.

  2003cited by this paper
• Ena/VASP proteins regulate cortical neuronal positioning.

  2002cited by this paper
• Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility.

  2002cited by this paper
• Contribution of Ena/VASP proteins to intracellular motility of listeria requires phosphorylation and proline-rich core but not F-actin binding or multimerization.

  2002cited by this paper
• Structure of the N-WASP EVH1 domain-WIP complex: insight into the molecular basis of Wiskott-Aldrich Syndrome.

  2002cited by this paper
• Regulation of focal complex composition and disassembly by the calcium-dependent protease calpain.

  2002cited by this paper
• Relaxation, equilibrium oligomerization, and molecular symmetry of the VASP (336-380) EVH2 tetramer.

  2002cited by this paper
• Targeting of Zyxin to Sites of Actin Membrane Interaction and to the Nucleus*

  2001cited by this paper
• Evidence for a molecular complex consisting of Fyb/SLAP, SLP-76, Nck, VASP and WASP that links the actin cytoskeleton to Fcgamma receptor signalling during phagocytosis.

  2001cited by this paper
• Phosphorylation of the Vasodilator-stimulated Phosphoprotein Regulates Its Interaction with Actin*

  2000cited by this paper
• LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity.

  2000cited by this paper
• Characterization of the Interaction between Zyxin and Members of the Ena/Vasodilator-stimulated Phosphoprotein Family of Proteins*

  2000cited by this paper
• Dual epitope recognition by the VASP EVH1 domain modulates polyproline ligand specificity and binding affinity

  2000cited by this paper
• Negative regulation of fibroblast motility by Ena/VASP proteins.

  2000cited by this paper
• Structure of a Ran-binding domain complexed with Ran bound to a GTP analogue: implications for nuclear transport

  1999cited by this paper
• VASP dynamics during lamellipodia protrusion

  1999cited by this paper
• The EVH2 Domain of the Vasodilator-stimulated Phosphoprotein Mediates Tetramerization, F-actin Binding, and Actin Bundle Formation*

  1999cited by this paper
• Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly.

  1999cited by this paper
• EVH1/WH1 domains of VASP and WASP proteins belong to a large family including Ran‐binding domains of the RanBP1 family

  1998cited by this paper
• Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains.

  1998cited by this paper
• A general computational framework for modeling cellular structure and function.

  1997cited by this paper
• A novel proline‐rich motif present in ActA of Listeria monocytogenes and cytoskeletal proteins is the ligand for the EVH1 domain, a protein module present in the Ena/VASP family

  1997cited by this paper
• The tandem repeat domain in the Listeria monocytogenes ActA protein controls the rate of actin-based motility, the percentage of moving bacteria, and the localization of vasodilator-stimulated phosphoprotein and profilin

  1996cited by this paper
• Molecular cloning, structural analysis and functional expression of the proline‐rich focal adhesion and microfilament‐associated protein VASP.

  1995cited by this paper
• Resonance assignment strategies for the analysis of nmr spectra of proteins

  1994cited by this paper
• The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts.

  1992cited by this paper
• On the attribution and additivity of binding energies.

  1981cited by this paper

• Ena/VASP-EVH1 inhibition prevents chemotaxis and metastasis by blocking the EVH1–WAVE2 interaction

  2025cites this paper
• Elaboration of the Homer1 Recognition Landscape Reveals Incomplete Divergence of Paralogous EVH1 Domains

  2024influential citation
• PairK: Pairwise k‐mer alignment for quantifying protein motif conservation in disordered regions

  2024cites this paper
• PairK: Pairwise k-mer alignment for quantifying protein motif conservation in disordered regions

  2024cites this paper
• Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH

  2022cites this paper
• Ena/VASP proteins in cell edge protrusion, migration and adhesion.

  2022cites this paper
• VASP localization to lipid bilayers induces polymerization driven actin bundle formation

  2022cites this paper
• A distributed residue network permits conformational binding specificity in a conserved family of actin remodelers

  2021cites this paper
• A proteome-wide screen uncovers diverse roles for sequence context surrounding proline-rich motifs in Ena/VASP molecular recognition

  2021cites this paper
• Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP proteins

  2021cites this paper
• Cytoskeletal Remodeling in Cancer

  2020cites this paper
• Cell Biology International

  2019cites this paper
• Quantification of reaction cycle parameters for an essential molecular switch in an auxin-responsive transcription circuit in rice

  2019cites this paper