Central nervous system (CNS) was considered as an “immunologically privileged site”. However, accumulating evidence supports a role for neuro inflammation in progress in Parkinson’s disease (PD). Not only the activated resident microglia in brains, cytokine levels in CNS and blood, the presence of auto antibodies, and the infiltration of T-cell in CNS also contribute disease progression. The interplay between innate and adaptive immunity in the pathobiology of PD will be focused on this article.
Involvement of Innate and Adaptive Immunity in Parkinson's Disease
Published 2017 in Journal of Neurology and Stroke
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- Publication year
2017
- Venue
Journal of Neurology and Stroke
- Publication date
2017-01-03
- Fields of study
Biology, Medicine
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Semantic Scholar
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