Soluble interleukin-2 receptors inhibit interleukin 2-dependent proliferation and cytotoxicity: explanation for diminished natural killer cell activity in cutaneous T-cell lymphomas in vivo?

No abstract is available for this paper.

• Publication year

  1992

• Venue

  Journal of Investigative Dermatology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/1523-1747.EP12494223PMID 1728640
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Stage-related decrease in natural killer cell activity in untreated patients with mycosis fungoides

  2004cited by this paper
• Shedding of ICAM-1 from human melanoma cell lines induced by IFN-gamma and tumor necrosis factor-alpha. Functional consequences on cell-mediated cytotoxicity.

  1991cited by this paper
• Regulation of alloreactivity in vivo by a soluble form of the interleukin-1 receptor.

  1990cited by this paper
• Purification of the IL-2 receptor (TAC) by ligand-affinity chromatography and utilization of the immobilized receptor for receptor-affinity chromatography (RAC) purification of IL-2, mutant IL-2, and IL-2 fusion proteins.

  1990cited by this paper
• Two tumor necrosis factor-binding proteins purified from human urine. Evidence for immunological cross-reactivity with cell surface tumor necrosis factor receptors.

  1990cited by this paper
• Identification of a soluble IL-2 receptor beta-chain from human lymphoid cell line cells.

  1990cited by this paper
• The murine interleukin-4 receptor: molecular cloning and characterization of secreted and membrane bound forms.

  1989cited by this paper
• Mutant proteins of human interleukin 2. Renaturation yield, proliferative activity and receptor binding.

  1989cited by this paper
• Soluble IL-2 receptor in rheumatoid arthritis. Correlation with disease activity, IL-1 and IL-2 inhibition.

  1988cited by this paper
• A competitive enzyme-linked immunoassay (ELISA) for the measurement of soluble human interleukin-2 receptors (IL-2R, Tac protein).

  1988cited by this paper
• Medium-scale ligand-affinity purification of two soluble forms of human interleukin-2 receptor.

  1988cited by this paper
• Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

  1988cited by this paper
• Structure-function relationships for the IL-2 receptor system. V. Structure-activity analysis of modified and truncated forms of the Tac receptor protein: site-specific mutagenesis of cysteine residues.

  1988cited by this paper
• Soluble interleukin-2 receptor levels in patients with undifferentiated and lymphoblastic lymphomas: correlation with survival.

  1987cited by this paper
• High-efficiency transformation of mammalian cells by plasmid DNA.

  1987cited by this paper
• Regulation of Human Large Granular Lymphocyte and T Cell Growth and Function by Recombinant Interleukin 2: Induction of Interleukin 2 Receptor and Promotion of Growth of Cells With Enhanced Cytotoxicity

  1987cited by this paper
• The released interleukin 2 receptor binds interleukin 2 efficiently.

  1986cited by this paper
• Soluble interleukin 2 receptors are released from activated human lymphoid cells in vitro.

  1985cited by this paper
• Measurement of cell numbers by means of the endogenous enzyme hexosaminidase. Applications to detection of lymphokines and cell surface antigens.

  1984cited by this paper
• Molecular cloning of cDNA encoding human interleukin-2 receptor

  1984cited by this paper
• Production of an epidermal growth factor receptor-related protein.

  1984cited by this paper
• Spontaneous release of the Leu-2 (T8) molecule from human T cells

  1983cited by this paper
• Decreased natural-killer-cell activity in cutaneous T-cell lymphomas.

  1983cited by this paper
• Decreased natural-killer-cell activity in cutaneous T-cell lymphomas.

  1983cited by this paper
• Sounding Boards. Management and financing of long-term-care services: a new approach to a chronic problem.

  1982cited by this paper
• Cutaneous Lymphomas, Pseudolymphomas, and Related Disorders

  1982cited by this paper
• T cell growth factor receptors. Quantitation, specificity, and biological relevance

  1981cited by this paper
• Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

  1979cited by this paper
• Report of the Committee on Staging and Classification of Cutaneous T-Cell Lymphomas.

  1979cited by this paper
• T cell growth factor: parameters of production and a quantitative microassay for activity.

  1978cited by this paper

• Simple dysmood disorder, a mild subtype of major depression, is not an inflammatory condition: Depletion of the compensatory immunoregulatory system.

  2025cites this paper
• Harnessing the immune system in the treatment of cutaneous T cell lymphomas

  2023influential citation
• Differential Effects of IL2Rα and IL15Rα over the Stability of the Common Beta-Gamma Signaling Subunits of the IL2 and IL15 Receptors

  2021cites this paper
• The Compensatory Immune-Regulatory Reflex System (CIRS) in Depression and Bipolar Disorder

  2018cites this paper
• Spinal Cord Injury: Are Interleukins a Molecular Link between Neuronal Damage and Ensuing Pathobiology?

  2015cites this paper
• Aggressive disease defined by cytogenetics is associated with cytokine dysregulation in CLL/SLL patients

  2013cites this paper
• Cutaneous Lymphoma, Leukemia and Related Disorders

  2010cites this paper
• Serum soluble interleukin 2 receptor α in human cancer of adults and children: a review

  2008influential citation
• Serum soluble interleukin 2 receptor alpha in human cancer of adults and children: a review.

  2008cites this paper
• The changes of protein kinase C activity in peripheral blood lymphocytes in the patients with obstructive jaundice and the implication

  2008cites this paper
• Serum levels of soluble HLA and IL-2R molecules in patients with urogenital chlamydia infection.

  2007cites this paper
• Phase II evaluation of gemcitabine monotherapy for cutaneous T-cell lymphoma.

  2006cites this paper
• Lack of suppressive CD4+CD25+FOXP3+ T cells in advanced stages of primary cutaneous T-cell lymphoma.

  2006cites this paper
• UVA suppresses shedding of ICAM-1 from interferon-γ (IFN-γ)-pretreated transformed keratinocytes

  2004cites this paper
• Serological Immunomarkers in Cutaneous T Cell Lymphoma

  2004cites this paper
• The interleukin-2 receptor in lesions and serum of bullous pemphigoid

  2004cites this paper
• Junctional CD8+ cutaneous lymphomas with nonaggressive clinical behavior: a CD8+ variant of mycosis fungoides?

  2002cites this paper
• The changes of protein kinase C activity in peripheral blood lymphocytes in the patients with obstructive jaundice and the implication.

  2001cites this paper
• Genotypic, phenotypic and functional analysis of CD4+CD7+ and CD4+CD7– T lymphocyte subsets in Sézary syndrome

  1999cites this paper
• Dysregulated Synthesis of Intracellular Type 1 and Type 2 Cytokines by T Cells of Patients with Cutaneous T-Cell Lymphoma

  1999cites this paper
• The difference in NK‐cell activity between patients with non‐Hodgkin's lymphomas and Hodgkin's disease

  1999cites this paper
• Analysis of Interleukin-2/Interleukin-2 Receptor System in Advanced Non-Small-Cell Lung Cancer

  1998cites this paper
• Defective IL-2 receptor expression in lymphocytes of patients with arsenic-induced Bowen’s disease

  1998cites this paper
• The dynamic interplay of malignant and benign T cells in cutaneous T-cell lymphoma.

  1997cites this paper
• Circulating interleukin-2 receptors are a group of multimeric proteins with immunoreactivity for interleukin-2 receptor alpha, beta, and gamma chains.

  1996cites this paper
• Synthesis of Cytokines During Tumour Development in Mice Immunized with the Mycobacterial Antigen Complex A60

  1996cites this paper
• Mycosis fungoides and Sezary syndrome.

  1996cites this paper
• Effects of moderate endurance exercise and training on in vitro lymphocyte proliferation, interleukin-2 (IL-2) production, and IL-2 receptor expression

  1996cites this paper
• Increased serum concentration of the soluble interleukin-2 receptor in cutaneous T-cell lymphoma. Clinical and prognostic implications.

  1996cites this paper
• Circulating Interleukin-2 Receptors Are a Group of Multimeric Proteins with Immunoreactivity for Interleukin-2 Receptor α, β, and γ Chains

  1996cites this paper
• Correlation of elevated plasma soluble IL-2 receptor levels with defective NK and CD8+ T-cells in myelodysplastic syndromes: is it part of a spectrum?

  1995cites this paper
• New perspectives in experimental and clinical research for cutaneous T cell lymphomas.

  1995cites this paper
• Neue Verfahren in der dermatoonkologischen Diagnostik

  1995cites this paper
• Skin Cancer: Basic Science, Clinical Research and Treatment

  1995cites this paper
• Shedding of Interleukin-2 Receptor in Cutaneous Lymphomas: An Effective Mechanism to Circumvent Immunosurveillance?

  1994cites this paper
• IMMUNOLOGIC PARAMETERS IN SYSTEMIC SCLEROSIS

  1994cites this paper
• The development of anti-interleukin-2 (IL-2) antibodies in cancer patients treated with recombinant IL-2.

  1994cites this paper
• Biclonal Sézary syndrome with capillary leak syndrome.

  1994cites this paper
• Various cytokines modulate ICAM-1 shedding on melanoma- and CTCL-derived cell lines: inverse regulation of ICAM-1 shedding in a Sézary cell line by interferon-gamma.

  1994cites this paper
• Soluble interleukin 2 receptors abrogate IL-2 induced activation of peripheral mononuclear cells.

  1994cites this paper
• Identification of a soluble receptor for platelet-derived growth factor in cell-conditioned medium and human plasma.

  1993cites this paper
• [Soluble interleukin 2 receptor as activity parameter in serum of systemic and discoid lupus erythematosus].

  1993cites this paper
• Mycosis fungoides. Diagnosis and pathogenesis.

  1993cites this paper
• UVA suppresses shedding of ICAM-1 from interferon-gamma (IFN-gamma)-pretreated transformed keratinocytes.

  1993cites this paper
• Evidence for cell‐mediated immune mechanisms in the pathology of pemphigus

  1993cites this paper
• Soluble interleukin-2 receptors and cutaneous T-cell lymphoma.

  1993cites this paper
• Biological significance of soluble IL-2 receptor

  1993cites this paper
• Peripheral blood mononuclear cells in patients with nonleukemic cutaneous T-cell lymphoma. Reduced proliferation and preferential secretion of a T helper-2-like cytokine pattern on stimulation.

  1993cites this paper
• Soluble interleeukin‐2 receptors and cutaneous t‐cell lymphoma

  1993cites this paper
• Soluble interleukin‐2 receptor in Sézary syndrome: its origin and clinical application

  1993cites this paper
• Serum levels of soluble interleukin-2 receptor in systemic and circumscribed scleroderma.

  1992cites this paper
• The interleukin 2 receptor in the hypereosinophilic syndrome.

  1992cites this paper