Cloning and Expression in Saccharomyces cerevisiae of a Synthetic Gene for the Type-I Trophoblast Interferon Ovine Trophoblast Protein-1: Purification and Antiviral Activity

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Journal of Interferon Research

• Publication date

  1991-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/jir.1991.11.357PMID 1800584
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Physiological mechanisms of pregnancy recognition in ruminants.

  2019cited by this paper
• Antiproliferative activity of a pregnancy recognition hormone, ovine trophoblast protein-1.

  1991cited by this paper
• The production, purification, and bioactivity of recombinant bovine trophoblast protein-1 (bovine trophoblast interferon).

  1990cited by this paper
• Evidence for extended maintenance of the corpus luteum by uterine infusion of a recombinant trophoblast alpha-interferon (trophoblastin) in sheep.

  1990cited by this paper
• Localization of an antiviral site on the pregnancy recognition hormone, ovine trophoblast protein 1.

  1990cited by this paper
• Molecular Cloning and Characterization of Complementary Deoxyribonucleic Acids Corresponding to Bovine Trophoblast Protein-1: A Comparison with Ovine Trophoblast Protein-1 and Bovine Interferon-αII

  1989cited by this paper
• Cloning and expression of cDNA encoding ovine trophoblastin: its identity with a class-II alpha interferon.

  1989cited by this paper
• Increasing gene expression in yeast by fusion to ubiquitin.

  1989cited by this paper
• Molecular cloning and characterization of complementary deoxyribonucleic acids corresponding to bovine trophoblast protein-1: a comparison with ovine trophoblast protein-1 and bovine interferon-alpha II.

  1989cited by this paper
• Maternal recognition of pregnancy in the goat: effects of conceptus removal on interestrus intervals and characterization of conceptus protein production during early pregnancy.

  1989cited by this paper
• High-Level Expression and In Vivo Processing of Chimeric Ubiquitin Fusion Proteins in Saccharomyces Cerevisiae

  1989cited by this paper
• Effect of ovine conceptus secretory proteins and purified ovine trophoblast protein-1 on interoestrous interval and plasma concentrations of prostaglandins F-2 alpha and E and of 13,14-dihydro-15-keto prostaglandin F-2 alpha in cyclic ewes.

  1988cited by this paper
• Antiviral activity of the pregnancy recognition hormone ovine trophoblast protein-1.

  1988cited by this paper
• Development of a radioimmunoassay for ovine trophoblast protein-1, the antiluteolytic protein from the sheep conceptus.

  1988cited by this paper
• Cloning in Yeast

  1987cited by this paper
• Cassette mutagenesis: an efficient method for generation of multiple mutations at defined sites.

  1985cited by this paper
• A novel class of human type I interferons

  1985cited by this paper
• Characterization of proteins produced in vitro by periattachment bovine conceptuses.

  1985cited by this paper
• Two distinct families of human and bovine interferon-alpha genes are coordinately expressed and encode functional polypeptides

  1985cited by this paper
• Roles of the 29-138 disulfide bond of subtype A of human alpha interferon in its antiviral activity and conformational stability.

  1984cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• Conceptus signaling markers in immune cells enhance pregnancy prediction in beef cattle

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  2021cites this paper
• Maternal recognition of pregnancy.

  2019cites this paper
• Mechanisms for the establishment and maintenance of pregnancy: synergies from scientific collaborations†

  2018cites this paper
• Chronicling the discovery of interferon tau.

  2017cites this paper
• Expression and molecular cloning of interferon stimulated genes in buffalo (Bubalus bubalis).

  2017cites this paper
• The evolution of interferon-tau.

  2017cites this paper
• History of Maternal Recognition of Pregnancy.

  2015cites this paper
• Expression and purification of buffalo interferon-tau and efficacy of recombinant buffalo interferon-tau for in vitro embryo development.

  2015cites this paper
• Short Peptide Type I Interferon Mimetics: Therapeutics for Experimental Allergic Encephalomyelitis, Melanoma, and Viral Infections

  2014cites this paper
• Pregnancy recognition signaling mechanisms in ruminants and pigs

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• Biological Activity of Recombinant Bovine Interferon τ Produced by a Silkworm-Baculovirus Gene Expression System

  2013cites this paper
• Contributions of an animal scientist to understanding the biology of the uterus and pregnancy.

  2012cites this paper
• Impact of preovulatory estradiol concentrations on conceptus development and uterine gene expression.

  2012cites this paper
• Contributions of an Animal Scientist to Reproductive Biology

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• Effects of Early Conceptus Signals on Circulating Immune Cells: Lessons from Domestic Ruminants

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• THE EFFECT OF LENGTH OF THE PREOVULATORY PERIOD ON MECHANISMS REGULATING EMBRYONIC SURVIVAL IN BEEF CATTLE

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• Interferon-τ: Current Applications and Potential in Antiviral Therapy

  2010cites this paper
• High periconceptional protein intake modifies uterine and embryonic relationships increasing early pregnancy losses and embryo growth retardation in sheep.

  2009cites this paper
• Encapsulated interferon-tau during Theiler's virus-induced demyelinating disease: efficacy of treatment and immune response profile

  2009cites this paper
• Impact of preovulatory estradiol concentrations on mechanisms affecting fertility in cattle

  2007cites this paper
• The effect of interferon-tau and ovarian steroids on the proliferation of bovine endometrial cells in vitro.

  2006cites this paper
• Differential effect of IFN-tau on proliferation and distribution of lymphocyte subsets in one-way mixed lymphocyte reaction in cows and heifers.

  2006cites this paper
• Establishment of a large-scale purification procedure for purified recombinant bovine interferon-tau produced by a silkworm-baculovirus gene expression system.

  2004cites this paper
• Expression of cyclooxygenase-2 and granulocyte-macrophage colony-stimulating factor in the endometrial epithelium of the cow is up-regulated during early pregnancy and in response to intrauterine infusions of interferon-tau.

  2004cites this paper
• Expression of Cyclooxygenase-2 and Granulocyte-Macrophage Colony-Stimulating Factor in the Endometrial Epithelium of the Cow Is Up-Regulated During Early Pregnancy and in Response to Intrauterine Infusions of Interferon-τ1

  2004cites this paper
• Possible role of interferon-tau on in vitro development of bovine embryos.

  2003cites this paper
• Influence of Different Isoforms of Recombinant Trophoblastic Interferons on Prostaglandin Production in Cultured Bovine Endometrial Cells1

  2003cites this paper
• Ovine Placental Lactogen Specifically Binds to Endometrial Glands of the Ovine Uterus1

  2003cites this paper
• Phenotypic and Ultrastructural Characteristics of Bronchoalveolar Lavage Cells of Lentivirus-Infected Lambs Treated with Recombinant Ovine IFN-τ

  2001cites this paper
• Effects of recombinant ovine interferon-tau on ovine lentivirus replication and progression of disease.

  2000cites this paper
• Interferon-Tau Stimulates Granulocyte-Macrophage Colony-Stimulating Factor Gene Expression in Bovine Lymphocytes and Endometrial Stromal Cells1

  2000cites this paper
• Acute-Phase Proteins and Hematologic Values in Ovine Lentivirus-Infected Lambs Treated with Recombinant Ovine IFN-tau

  2000cites this paper
• Detection and Regulation of the Messenger for a Putative Bovine Endometrial 9-Keto-Prostaglandin E2 Reductase: Effect of Oxytocin and Interferon-Tau1

  2000cites this paper
• A classification for the interferon-tau.

  2000cites this paper
• A Classification for the Interferon-τ

  2000cites this paper
• Interferon tau–induced hepatocyte apoptosis in sheep

  2000cites this paper
• IFN-τ Exhibits Potent Suppression of Human Papillomavirus E6/E7 Oncoprotein Expression

  1999cites this paper
• The Cross-Species Antiviral Activities of Different IFN-tau Subtypes on Bovine, Murine, and Human Cells: Contradictory Evidence for Therapeutic Potential

  1999cites this paper
• Crystal structure of ovine interferon-tau at 2.1 A resolution.

  1999cites this paper
• Identification of the expressed forms of ovine interferon-tau in the periimplantation conceptus: sequence relationships and comparative biological activities.

  1999cites this paper
• Differential Effects of Type I IFNs on the Growth of WC1− CD8+ γδ T Cells and WC1+ CD8− γδ T Cells In Vitro

  1999cites this paper
• Differential effects of intrauterine and subcutaneous administration of recombinant ovine interferon tau on the endometrium of cyclic ewes.

  1999cites this paper
• Effects of recombinant ovine interferon tau, placental lactogen, and growth hormone on the ovine uterus.

  1999cites this paper
• Platelet-activating factor may act as an endogenous pulse generator for sheep of luteolytic PGF2αrelease.

  1999cites this paper
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  1999cites this paper
• Differential effects of type I IFNs on the growth of WC1- CD8+ gamma delta T cells and WC1+ CD8- gamma delta T cells in vitro.

  1999cites this paper
• Expression of the interferon tau inducible ubiquitin cross-reactive protein in the ovine uterus.

  1999cites this paper
• Clinical effects of the recombinant feline interferon-omega on experimental parvovirus infection in beagle dogs.

  1998cites this paper
• Different ovine interferon-tau genes are not expressed identically and their protein products display different activities.

  1998cites this paper
• Loss of the signature six carboxyl amino acid tail from ovine interferon-tau does not affect biological activity.

  1998cites this paper
• Expression of interferon regulatory factors one and two in the ovine endometrium: effects of pregnancy and ovine interferon tau.

  1998cites this paper
• In vitro response to oxytocin and interferon-Tau in bovine endometrial cells from caruncular and inter-caruncular areas.

  1998cites this paper
• Structural responses of pulmonary intravascular macrophages in lentivirus‐infected and/or recombinant ovine interferon‐τ–treated lambs

  1998cites this paper
• IFN-tau: a novel subtype I IFN1. Structural characteristics, non-ubiquitous expression, structure-function relationships, a pregnancy hormonal embryonic signal and cross-species therapeutic potentialities.

  1998cites this paper
• Recombinant ovine and bovine interferons tau regulate prostaglandin production and oxytocin response in cultured bovine endometrial cells.

  1997cites this paper
• Recent developments and potentialities for reducing embryo mortality in ruminants: the role of IFN-tau and other cytokines in early pregnancy.

  1997cites this paper
• Cellular Mechanisms Involved during Oxytocin-Induced Prostaglandin F2α Production in Endometrial Epithelial Cells in Vitro: Role of Cyclooxygenase-2.

  1997cites this paper
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  1997cites this paper
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  1997cites this paper
• Lack of effect of granulocyte-macrophage colony-stimulating factor on secretion of interferon-tau, other proteins, and prostaglandin E2 by the bovine and ovine conceptus.

  1997cites this paper
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  1997cites this paper
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  1997cites this paper
• Potent anti-feline immunodeficiency virus and anti-human immunodeficiency virus effect of IFN-tau.

  1997cites this paper
• Effects of exogenous recombinant ovine interferon tau on circulating concentrations of progesterone, cortisol, luteinizing hormone, and antiviral activity; interestrous interval; rectal temperature; and uterine response to oxytocin in cyclic ewes.

  1997cites this paper
• High yield expression and secretion of the ovine pregnancy recognition hormone interferon-tau by Pichia pastoris.

  1996cites this paper
• Ovine interferon tau suppresses transcription of the estrogen receptor and oxytocin receptor genes in the ovine endometrium.

  1996cites this paper
• Effects of Recomintert Interferon-τ on Ovine Lentivirus Replication

  1996cites this paper
• Effects of interferon-tau and progesterone on oestrogen-stimulated expression of receptors for oestrogen, progesterone and oxytocin in the endometrium of ovariectomized ewes.

  1996cites this paper
• Biochemical and immunological properties of related small ruminant trophoblast interferons.

  1996cites this paper
• High Yield Expression and Secretion of the Ovine Pregnancy Recognition Hormone Interferon-τ by Pichia pastoris

  1996cites this paper
• Placental Interferons

  1996cites this paper
• Ubiquitin cross-reactive protein is released by the bovine uterus in response to interferon during early pregnancy.

  1996cites this paper
• tau-Interferon: pregnancy recognition signal in ruminants.

  1996cites this paper
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  1996cites this paper
• Secretion of bovine uterine proteins in response to type I interferons.

  1995cites this paper
• Intrauterine injection of ovine interferon-tau alters oestrogen receptor and oxytocin receptor expression in the endometrium of cyclic ewes.

  1995cites this paper
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  1995cites this paper
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  1995cites this paper
• Regulation of Endometrial Responsiveness to Estrogen and Progesterone by Pregnancy Recognition Signals During the Periimplantation Period

  1995cites this paper
• Extension of Corpus Luteum Lifespan and Reduction of Uterine Secretion of Prostaglandin F2α of Cows in Response to Recombinant Interferon-τ

  1995cites this paper
• Extension of corpus luteum lifespan and reduction of uterine secretion of prostaglandin F2 alpha of cows in response to recombinant interferon-tau.

  1995cites this paper
• The IFN pregnancy recognition hormone IFN-tau blocks both development and superantigen reactivation of experimental allergic encephalomyelitis without associated toxicity.

  1995cites this paper
• Predicted structural motif of IFN tau.

  1994cites this paper
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  1994cites this paper
• Cytokines and Pregnancy Recognition

  1994cites this paper
• Delayed luteolysis and suppression of testosterone secretion after recombinant ovine interferon treatment in goats (Capra hircus).

  1994cites this paper
• Structure/Function Studies with Interferon Tau: Evidence for Multiple Active Sites

  1994cites this paper
• Intrauterine injection of recombinant ovine interferon-tau extends the interestrous interval in sheep.

  1993cites this paper
• Differential expression of distinct mRNAs for ovine trophoblast protein-1 and related sheep type I interferons.

  1993cites this paper
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  1992cites this paper
• Type I Conceptus Interferons: Maternal Recognition of Pregnancy Signals and Potential Therapeutic Agents

  1991cites this paper
• Expression of Cyclooxygenase-2 and Granulocyte-Macrophage Colony-Stimulating Factor in the Endometrial Epithelium of the Cow Is Up-Regulated During Early Pregnancy and in Response to Intrauterine Infusions of Interferon-t1

  year unknowncites this paper