Molecular polymorphism of Kaposi's sarcoma-associated herpesvirus (Human herpesvirus 8) latent nuclear antigen: evidence for a large repertoire of viral genotypes and dual infection with different viral genotypes.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Journal of Infectious Diseases

• Publication date

  1999-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1086/315098PMID 10515805
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization and Cell Cycle Regulation of the Major Kaposi’s Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Latent Genes and Their Promoter

  1999cited by this paper
• Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen.

  1999cited by this paper
• Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma.

  1999cited by this paper
• Geographically distinct HHV-8 DNA sequences in Saudi Arabian Iatrogenic Kaposi's sarcoma lesions.

  1998cited by this paper
• Human herpesvirus 8 group B and C variants circulating in São Paulo, Brazil.

  1998cited by this paper
• Study of human herpesvirus 8 (HHV-8) variants from Kaposi's sarcoma in France: is HHV-8 subtype A responsible for more agressive tumors?

  1998cited by this paper
• Evidence for multiclonality in multicentric Kaposi's sarcoma.

  1998cited by this paper
• Novel organizational features, captured cellular genes, and strain variability within the genome of KSHV/HHV8.

  1998cited by this paper
• Human herpesvirus 8 strain variability in clinical conditions other than Kaposi's sarcoma

  1997cited by this paper
• Strain variability among Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genomes: evidence that a large cohort of United States AIDS patients may have been infected by a single common isolate

  1997cited by this paper
• Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells

  1997cited by this paper
• Presence of human herpesvirus 8 variants in the oral tissues of human immunodeficiency virus-infected persons.

  1997influential reference
• The 222- to 234-kilodalton latent nuclear protein (LNA) of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) is encoded by orf73 and is a component of the latency-associated nuclear antigen

  1997cited by this paper
• Molecular analysis of clonality in Kaposi's sarcoma.

  1997cited by this paper
• Clonality in Kaposi's sarcoma.

  1997cited by this paper
• Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells

  1997cited by this paper
• Monoclonal origin of multicentric Kaposi's sarcoma lesions.

  1997cited by this paper
• Clonality in Kaposi's sarcoma.

  1997cited by this paper
• Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8

  1997cited by this paper
• Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus.

  1996cited by this paper
• Prevalence of Kaposi's sarcoma associated herpesvirus infection measured by antibodies to recombinant capsid protein and latent immunofluorescence antigen.

  1996cited by this paper
• KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma

  1996influential reference
• Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae

  1996cited by this paper
• Lytic growth of Kaposi's sarcoma–associated herpesvirus (human herpesvirus 8) in culture

  1996cited by this paper
• Seroconversion to antibodies against Kaposi's sarcoma-associated herpesvirus-related latent nuclear antigens before the development of Kaposi's sarcoma.

  1996influential reference
• Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8).

  1996cited by this paper
• The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma–associated herpesvirus): Distribution of infection in KS risk groups and evidence for sexual transmission

  1996cited by this paper
• In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences.

  1995cited by this paper
• AIDS-related Kaposi's sarcoma is a clonal neoplasm.

  1995cited by this paper
• Detection of A-type and B-type Epstein-Barr virus in throat washings and lymphocytes.

  1994cited by this paper
• Detection of multiple 'Ebnotypes' in individual Epstein-Barr virus carriers following lymphocyte transformation by virus derived from peripheral blood and oropharynx.

  1994cited by this paper
• The Epstein-Barr virus carrier state: dominance of a single growth-transforming isolate in the blood and in the oropharynx of healthy virus carriers.

  1991cited by this paper
• Genital human papillomavirus infection in female university students as determined by a PCR‐based method

  1991cited by this paper
• Epstein-Barr virus types 1 and 2 differ in their EBNA-3A, EBNA-3B, and EBNA-3C genes

  1990cited by this paper
• Coinfection with A- and B-type Epstein-Barr virus in human immunodeficiency virus-positive subjects.

  1990cited by this paper
• Lymphoblastoid cell lines and burkitt‐lymphoma‐derivee cell lines differ in the expression of a second epstein‐barr virus encoded nuclear antigen

  1986cited by this paper
• Geographical prevalence of two types of Epstein-Barr virus.

  1986cited by this paper

• Engineered protein destabilization reverses intrinsic immune evasion for candidate vaccine pan-strain KSHV and SARS-CoV-2 antigens

  2024cites this paper
• A simple method for rapid cloning of complete herpesvirus genomes

  2024cites this paper
• Genomic diversity and natural recombination of equid gammaherpesvirus 5 isolates.

  2023cites this paper
• Variation within major internal repeats of KSHV in vivo

  2023cites this paper
• Virus–Host Interplay Between Poly (ADP-Ribose) Polymerase 1 and Oncogenic Gammaherpesviruses

  2022cites this paper
• Whole-genome sequencing of Kaposi sarcoma-associated herpesvirus (KSHV/HHV8) reveals evidence for two African lineages.

  2022cites this paper
• Reversible switching of primary cells between normal and malignant state by oncogenic virus KSHV and CRISPR/Cas9‐mediated targeting of a major viral latent protein

  2021cites this paper
• Latently KSHV-Infected Cells Promote Further Establishment of Latency upon Superinfection with KSHV

  2021cites this paper
• Authorship Patterns in Cancer Genomics Publications Across Africa

  2021cites this paper
• Dual infection and recombination of Kaposi sarcoma herpesvirus revealed by whole-genome sequence analysis of effusion samples.

  2020cites this paper
• The Critical Role of Genome Maintenance Proteins in Immune Evasion During Gammaherpesvirus Latency

  2019cites this paper
• Evaluation of the therapeutic potential of several compounds in human herpesvirus 8 using a chimera virus mouse infection model

  2019cites this paper
• KSHV Genome Replication and Maintenance in Latency.

  2018cites this paper
• Molecular Biology of KSHV in Relation to HIV/AIDS-Associated Oncogenesis.

  2018cites this paper
• Full-Length Isoforms of Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen Accumulate in the Cytoplasm of Cells Undergoing the Lytic Cycle of Replication

  2017cites this paper
• Kaposi's Sarcoma-Associated Herpesvirus (KSHV/HHV8)

  2017cites this paper
• HIV Infection and AIDS

  2017cites this paper
• Cell Cycle Regulatory Functions of the KSHV Oncoprotein LANA

  2016cites this paper
• Molecular Analysis of South African Ovine Herpesvirus 2 Strains Based on Selected Glycoprotein and Tegument Genes

  2016cites this paper
• KSHV Genome Replication and Maintenance

  2016cites this paper
• Human DNA tumor viruses generate alternative reading frame proteins through repeat sequence recoding

  2014influential citation
• Complex Alternative Cytoplasmic Protein Isoforms of the Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen 1 Generated through Noncanonical Translation Initiation

  2012cites this paper
• Virus-host cell interplay in the pathogenesis of Kaposi's sarcoma herpesvirus

  2012cites this paper
• Identification of the Determinants of Latency and Replication for Rhesus Rhadinovirus (RRV)

  2012cites this paper
• Mechanisms of Kaposi's Sarcoma-Associated Herpesvirus Latency and Reactivation

  2011cites this paper
• The Internal Kaposi's Sarcoma-Associated Herpesvirus LANA Regions Exert a Critical Role on Episome Persistence

  2011cites this paper
• The latency-associated nuclear antigen, a multifunctional protein central to Kaposi's sarcoma-associated herpesvirus latency.

  2011cites this paper
• To reactivate or not to reactivate : Control of KSHV lytic replication is essential for apoptosis in response to p53 restoration

  2010cites this paper
• Immune evasion by gammaherpesvirus genome maintenance proteins.

  2010cites this paper
• Extensive oral shedding of human herpesvirus 8 in a renal allograft recipient.

  2009cites this paper
• Kaposi’s Sarcoma-Associated Herpesvirus

  2009cites this paper
• A comparative study of the frequency of antibody and titers against human herpesvirus 8 latent and lytic antigens in “at‐risk” individuals and among patients with Kaposi's sarcoma

  2009cites this paper
• Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional program.

  2008cites this paper
• Reduction in RNA Levels Rather than Retardation of Translation Is Responsible for the Inhibition of Major Histocompatibility Complex Class I Antigen Presentation by the Glutamic Acid-Rich Repeat of Herpesvirus Saimiri Open Reading Frame 73

  2008cites this paper
• Reflections on the interpretation of heterogeneity and strain differences based on very limited PCR sequence data from Kaposi's sarcoma-associated herpesvirus genomes.

  2007cites this paper
• Complete sequence and analysis of the ovine herpesvirus 2 genome.

  2007cites this paper
• AIDS-ASSOCIATED VIRAL ONCOGENESIS Cancer Treatment and Research

  2007cites this paper
• Structure and function of latency-associated nuclear antigen.

  2007cites this paper
• KAPOSI’S SARCOMA-ASSOCIATED HERPESVIRUS-ENCODED CYCLIN, K- CYCLIN ENHANCES NF-KAPPAB-DEPENDENT TRANSCRIPTION AND INTERACTS WITH LATENCY-ASSOCIATED NUCLEAR ANTIGEN IN VIRAL AND NON-VIRALLY INFECTED CELLS

  2007cites this paper
• Salivary human herpesvirus 8 shedding in renal allograft recipients with Kaposi's sarcoma

  2007cites this paper
• Comparison of ovine herpesvirus 2 genomes isolated from domestic sheep (Ovis aries) and a clinically affected cow (Bos bovis).

  2007cites this paper
• Molecular biology of KSHV in relation to AIDS-associated oncogenesis.

  2007cites this paper
• Recurrent genomic imbalances in primary effusion lymphomas.

  2006cites this paper
• The Minimal Replicator Element of the Kaposi's Sarcoma-Associated Herpesvirus Terminal Repeat Supports Replication in a Semiconservative and Cell-Cycle-Dependent Manner

  2006cites this paper
• KSHV/HHV-8 infection of human hematopoietic progenitor (CD34+) cells: persistence of infection during hematopoiesis in vitro and in vivo.

  2006cites this paper
• RFHVMn ORF73 is structurally related to the KSHV ORF73 latency-associated nuclear antigen (LANA) and is expressed in retroperitoneal fibromatosis (RF) tumor cells.

  2006influential citation
• KSHV / HHV-8 infection of human hematopoietic progenitor ( CD 34 ) cells : persistence of infection during hematopoiesis in vitro and in vivo

  2006cites this paper
• Genotypic distribution of human herpesvirus-8 strains circulating in HIV-positive patients with and without Kaposi’s sarcoma in Hungary

  2005cites this paper
• Genomic Variation of the Fibropapilloma-Associated Marine Turtle Herpesvirus across Seven Geographic Areas and Three Host Species

  2005cites this paper
• Multiple infection by human herpesvirus-8 and cytomegalovirus.

  2005cites this paper
• A naturally occurring C-terminal truncated isoform of the latent nuclear antigen of Kaposi's sarcoma-associated herpesvirus does not associate with viral episomal DNA.

  2004cites this paper
• Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Up-Regulates Transcription of Human Telomerase Reverse Transcriptase Promoter through Interaction with Transcription Factor Sp1

  2004cites this paper
• KSHV LANA1 binds DNA as an oligomer and residues N-terminal to the oligomerization domain are essential for DNA binding, replication, and episome persistence.

  2004cites this paper
• Lytic Replication-Defective Kaposi's Sarcoma-Associated Herpesvirus: Potential Role in Infection and Malignant Transformation

  2004influential citation
• Epidemiology of Multiple Myeloma and Related Disease

  2004cites this paper
• Molecular genetics and functions of Kaposi's sarcoma-associated herpesvirus glycoproteins in viral entry and virus-induced cell fusion

  2004cites this paper
• Disruption of Kaposi's Sarcoma-Associated Herpesvirus Latent Nuclear Antigen Leads to Abortive Episome Persistence

  2004cites this paper
• Multiple human herpesvirus-8 infection.

  2003cites this paper
• Global Changes in Kaposi's Sarcoma-Associated Virus Gene Expression Patterns following Expression of a Tetracycline-Inducible Rta Transactivator

  2003cites this paper
• Productive Lytic Replication of a Recombinant Kaposi's Sarcoma-Associated Herpesvirus in Efficient Primary Infection of Primary Human Endothelial Cells

  2003cites this paper
• Molecular Genetics of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Epidemiology and Pathogenesis

  2003influential citation
• Suppression of Tetradecanoyl Phorbol Acetate-Induced Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus by K1 Signal Transduction

  2002cites this paper
• The KSHV latency-associated nuclear antigen: a multifunctional protein.

  2002cites this paper
• Isolation and expression of three open reading frames from ovine herpesvirus-2.

  2002cites this paper
• Tracking familial transmission of Kaposi's sarcoma-associated herpesvirus using restriction fragment length polymorphism analysis of latent nuclear antigen.

  2002cites this paper
• Efficient Infection by a Recombinant Kaposi's Sarcoma-Associated Herpesvirus Cloned in a Bacterial Artificial Chromosome: Application for Genetic Analysis

  2002influential citation
• The Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus Supports Latent DNA Replication in Dividing Cells

  2002cites this paper
• DNA Binding and Modulation of Gene Expression by the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus

  2001influential citation
• Kaposi's sarcoma occurring during short-term dialysis: report of two cases.

  2001cites this paper
• The Latency-associated Nuclear Antigen of Kaposi's Sarcoma-associated Herpesvirus Transactivates the Telomerase Reverse Transcriptase Promoter*

  2001cites this paper
• gpUL73 (gN) genomic variants of human cytomegalovirus isolates are clustered into four distinct genotypes.

  2001influential citation
• Close but Distinct Regions of Human Herpesvirus 8 Latency-Associated Nuclear Antigen 1 Are Responsible for Nuclear Targeting and Binding to Human Mitotic Chromosomes

  2001cites this paper
• The biology of Kaposi's sarcoma.

  2001cites this paper
• The Kaposi's Sarcoma-Associated Herpesvirus Latency-Associated Nuclear Antigen

  2001cites this paper
• Distinct distribution of rare US genotypes of Kaposi's sarcoma-associated herpesvirus (KSHV) in South Texas: implications for KSHV epidemiology.

  2001cites this paper
• Primary effusion lymphoma: a liquid phase lymphoma of fluid-filled body cavities.

  2001cites this paper
• Modulation of Cellular and Viral Gene Expression by the Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus

  2001cites this paper
• Evolutionary aspects of oncogenic herpesviruses

  2000cites this paper
• Absence of herpesvirus DNA sequences in the 5T murine model of human multiple myeloma

  2000cites this paper
• Molecular evidence of organ-related transmission of Kaposi sarcoma-associated herpesvirus or human herpesvirus-8 in transplant patients.

  2000cites this paper
• Hot-spot variations of Kaposi's sarcoma-associated herpesvirus latent nuclear antigen and application in genotyping by PCR-RFLP.

  2000cites this paper