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Clinical Usefulness of Imaging and Blood Cultures in Cellulitis Evaluation

L. Ko,A. C. Garza-Mayers,J. St John,L. Strazzula,P. Vedak,A. Dobry,D. Kroshinsky

Published 2018 in JAMA Internal Medicine

ABSTRACT

volve a shorter duration of antibiotic exposure.6 Our study has limitations. First, we were not able to account for underlying conditions or other indicators for longer courses of antibiotic therapy. Second, by excluding visits with a diagnosis of unspecified sinusitis from our analysis, we may have excluded some cases of acute sinusitis. However, the findings of a sensitivity analysis that included cases of both acute and unspecified sinusitis were similar (median duration of therapy, 10.0 days; 88.1% [95% CI, 85.1%-91.0%] of nonazithromycin antibiotic courses were 10 days or longer in duration). Outpatient antibiotic stewardship programs can optimize infection management by ensuring guideline-concordant treatment, including the use of minimum effective durations of antibiotic therapy. The durations of most courses of antibiotic therapy for adult outpatients with sinusitis exceed guideline recommendations, which represents an opportunity to reduce the unnecessary use of antibiotics when therapy with antibiotics is indicated.

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