Imbalanced Production of Cytokines by T Cells Associates with the Activation/Exhaustion Status of Memory T Cells in Chronic HIV Type 1 Infection

No abstract is available for this paper.

• Publication year

  2012

• Venue

  AIDS Research and Human Retroviruses

• Publication date

  2012-06-25

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1089/aid.2011.0073PMID 21902582
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Short communication: CD8(+) T cell polyfunctionality profiles in progressive and nonprogressive pediatric HIV type 1 infection.

  2011cited by this paper
• Phenotypic and Functional Profile of HIV-Inhibitory CD8 T Cells Elicited by Natural Infection and Heterologous Prime/Boost Vaccination

  2010cited by this paper
• Cytotoxic granule release dominates gag-specific CD4+ T-cell response in different phases of HIV infection

  2010cited by this paper
• Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

  2009cited by this paper
• Interleukin-17 is required for T helper 1 cell immunity and host resistance to the intracellular pathogen Francisella tularensis.

  2009cited by this paper
• Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques

  2008cited by this paper
• Simian immunodeficiency virus–induced mucosal interleukin-17 deficiency promotes Salmonella dissemination from the gut

  2008cited by this paper
• The biological functions of T helper 17 cell effector cytokines in inflammation.

  2008cited by this paper
• Human Th17 Cells Share Major Trafficking Receptors with Both Polarized Effector T Cells and FOXP3+ Regulatory T Cells1

  2008cited by this paper
• HIV infection and the gastrointestinal immune system

  2008cited by this paper
• Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections.

  2008cited by this paper
• Phenotype and function of human T lymphocyte subsets: Consensus and issues

  2008cited by this paper
• Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

  2007cited by this paper
• PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status

  2007cited by this paper
• Upregulation of PD-1 Expression on HIV-Specific CD8+ T Cells Leads to Reversible Immune Dysfunction

  2007cited by this paper
• Surface phenotype and antigenic specificity of human interleukin 17–producing T helper memory cells

  2007cited by this paper
• CCL3L1 and CCR5 influence cell-mediated immunity and affect HIV-AIDS pathogenesis via viral entry-independent mechanisms

  2007cited by this paper
• Programmed Death 1 Expression on HIV-Specific CD4+ T Cells Is Driven by Viral Replication and Associated with T Cell Dysfunction1

  2007cited by this paper
• PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

  2006cited by this paper
• HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T cells.

  2006cited by this paper
• Pathogenesis of HIV infection: what the virus spares is as important as what it destroys

  2006cited by this paper
• Microbial translocation is a cause of systemic immune activation in chronic HIV infection

  2006cited by this paper
• Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

  2006cited by this paper
• Microbial translocation is a cause of systemic immune activation in chronic HIV infection

  2006cited by this paper
• The Influence of CCL3L1 Gene-Containing Segmental Duplications on HIV-1/AIDS Susceptibility

  2005cited by this paper
• Functional and Phenotypic Characterization of CD57+CD4+ T Cells and Their Association with HIV-1-Induced T Cell Dysfunction1

  2005cited by this paper
• Interleukin 17–producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

  2005cited by this paper
• Memory CD8 T-Cell Differentiation during Viral Infection

  2004cited by this paper
• Tax protein of human T-cell leukaemia virus type 1 induces interleukin 17 gene expression in T cells.

  2004cited by this paper
• What can natural infection of African monkeys with simian immunodeficiency virus tell us about the pathogenesis of AIDS?

  2004cited by this paper
• Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

  2003cited by this paper
• Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment

  2003cited by this paper
• Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells.

  2003cited by this paper
• In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines

  2002cited by this paper
• Activation of monocytic cells through Fc gamma receptors induces the expression of macrophage-inflammatory protein (MIP)-1 alpha, MIP-1 beta, and RANTES.

  2002cited by this paper
• Activation of Monocytic Cells Through Fcγ Receptors Induces the Expression of Macrophage-Inflammatory Protein (MIP)-1α, MIP-1β, and RANTES1

  2002cited by this paper
• Antigen-specific production of RANTES, macrophage inflammatory protein (MIP)-1alpha, and MIP-1beta in vitro is a correlate of reduced human immunodeficiency virus burden in vivo.

  2000cited by this paper
• Chromatin-based regulatory mechanisms governing cytokine gene transcription.

  1999cited by this paper
• Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

  1999cited by this paper
• Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

  1999cited by this paper
• Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s

  1998influential reference
• T helper 1 and T helper 2 cells respond differentially to chemokines.

  1998cited by this paper
• Plasma Viral Load and CD4+ Lymphocytes as Prognostic Markers of HIV-1 Infection

  1997cited by this paper
• The Th1/Th2 balance in autoimmunity.

  1995cited by this paper
• Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells.

  1995cited by this paper
• Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8+ T Cells

  1995cited by this paper
• Preferential migration of activated CD4+ and CD8+ T cells in response to MIP-1 alpha and MIP-1 beta

  1993cited by this paper
• A TH1-->TH2 switch is a critical step in the etiology of HIV infection.

  1993cited by this paper
• Two essential regulatory elements in the human interferon gamma promoter confer activation specific expression in T cells

  1993cited by this paper
• TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.

  1989cited by this paper
• Human T cell activation with phytohemagglutinin. The function of IL-6 as an accessory signal.

  1988cited by this paper
• The basis for the immunoregulatory role of macrophages and other accessory cells.

  1987cited by this paper
• Mitogen-induced human IgG subclass expression.

  1984cited by this paper
• Mitogenic leukoagglutinin from Phaseolus vulgaris binds to a pentasaccharide unit in N-acetyllactosamine-type glycoprotein glycans.

  1982cited by this paper
• Lymphocyte activation. V. Quantitation of the proliferative responses to mitogens using defined T and B cell populations.

  1973cited by this paper

• Host Variation in Pneumonia Susceptibility

  2026cites this paper
• Characterization of proinflammatory cytokines profile during acute SARS-CoV-2 infection in people with human immunodeficiency virus.

  2024cites this paper
• The ecto-enzyme CD38 modulates CD4 T cell immunometabolic responses and participates in HIV pathogenesis.

  2024cites this paper
• HIV-1 Transcriptional Activator Tat Inhibits IL2 Expression by Preventing the Presence of Pol II on the IL2 Promoter

  2023cites this paper
• Expression Profile and Biological Role of Immune Checkpoints in Disease Progression of HIV/SIV Infection

  2022influential citation
• Sustainable Antiviral Efficacy of Rejuvenated HIV-Specific Cytotoxic T Lymphocytes Generated from Induced Pluripotent Stem Cells

  2022cites this paper
• Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals

  2021cites this paper
• Blockade of the PD-1 axis alone is not sufficient to activate HIV-1 virion production from CD4+ T cells of individuals on suppressive ART

  2019cites this paper
• Mechanisms of reactivation of latent tuberculosis infection due to SIV co-infection.

  2019cites this paper
• High Plasma Levels of sTNF-R1 and CCL11 Are Related to CD4+ T-Cells Fall in Human Immunodeficiency Virus Elite Controllers With a Sustained Virologic Control

  2018cites this paper
• Differential effects of HIV transmission from monocyte‐derived dendritic cells vs. monocytes to IL‐17+CD4+ T cells

  2017cites this paper
• Factors Leading to the Loss of Natural Elite Control of HIV-1 Infection

  2017cites this paper
• IL-23 signaling in Th17 cells is inhibited by HIV infection and is not restored by HAART: Implications for persistent immune activation

  2017cites this paper
• Increase in frequencies of circulating Th-17 cells correlates with microbial translocation, immune activation and exhaustion in HIV-1 infected patients with poor CD4 T-cell reconstitution.

  2016cites this paper
• Human Immunodeficiency Virus Infection and Host Defense in the Lungs

  2016cites this paper
• Candida albicans Stimulates IL-23 Release by Human Dendritic Cells and Downstream IL-17 Secretion by Vδ1 T Cells

  2015cites this paper
• 1 T Cells d IL-17 Secretion by V Human Dendritic Cells and Downstream Stimulates IL-23 Release by Candida albicans

  2015cites this paper
• Epigenetic repression of interleukin 2 expression in senescent CD4+ T cells during chronic HIV type 1 infection.

  2015cites this paper
• Genital herpes simplex virus type 2 infection in humanized HIV-transgenic mice triggers HIV shedding and is associated with greater neurological disease.

  2014cites this paper
• Transcriptional Regulation of CXCL5 in HIV-1-Infected Macrophages and Its Functional Consequences on CNS Pathology

  2014cites this paper
• Cytokine Diversity in the Th1-Dominated Human Anti-Influenza Response Caused by Variable Cytokine Expression by Th1 Cells, and a Minor Population of Uncommitted IL-2+IFNγ- Thpp Cells

  2014cites this paper
• Distortion of memory Vδ2 γδ T cells contributes to immune dysfunction in chronic HIV infection

  2014cites this paper
• Coinfection tuberculosis M. specific CD4 T Cells during SIV/ - Mycobacterium tuberculosis Production by Monocyte-Derived IL-5 Reduces TNF

  2013cites this paper
• Monocyte-Derived IL-5 Reduces TNF Production by Mycobacterium tuberculosis–specific CD4 T Cells during SIV/M. tuberculosis Coinfection

  2013cites this paper
• Structure of TCR and antigen complexes at an immunodominant CTL epitope in HIV-1 infection

  2013cites this paper
• Foxo 3 a : an integrator of immune dysfunction during HIV infection

  2013cites this paper
• Machine learning approaches to study HIV / AIDS infection : A Review

  2012cites this paper
• Foxo3a: an integrator of immune dysfunction during HIV infection.

  2012cites this paper
• SIV increases susceptibility to tuberculosis by manipulating M. tuberculosis-specific immunological responses

  2012cites this paper
• How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens?

  2012cites this paper