The growth capacity of bone marrow CD34 positive cells in culture is drastically reduced in a murine model of Down syndrome.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Comptes rendus. Biologies

• Publication date

  2006-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.CRVI.2006.06.004PMID 16945839
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Precocious aging of the immune system in Down syndrome: alteration of B lymphocytes, T-lymphocyte subsets, and cells with natural killer markers.

  2005cited by this paper
• Adult human hematopoietic stem cells produce neurons efficiently in the regenerating chicken embryo spinal cord.

  2005cited by this paper
• Mast cells as "tunable" effector and immunoregulatory cells: recent advances.

  2005cited by this paper
• Hematopoietic cells and osteoblasts are derived from a common marrow progenitor after bone marrow transplantation.

  2004cited by this paper
• AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis

  2004cited by this paper
• Mouse models of Down syndrome: how useful can they be? Comparison of the gene content of human chromosome 21 with orthologous mouse genomic regions.

  2003cited by this paper
• Hematopoietic progenitors express neural genes

  2003influential reference
• CD34 is a specific marker of mature murine mast cells.

  2002cited by this paper
• Multilineage development from adult bone marrow cells

  2002cited by this paper
• Pattern of malignant disorders in individuals with Down's syndrome.

  2001cited by this paper
• Ets target genes: past, present and future

  2000cited by this paper
• Hematopoietic stem cell quiescence maintained by p21cip1/waf1.

  2000cited by this paper
• Role of Founder Cell Deficit and Delayed Neuronogenesis in Microencephaly of the Trisomy 16 Mouse

  2000cited by this paper
• Hematopoietic deficiencies and core binding factor expression in murine Ts16, an animal model for Down syndrome.

  1999cited by this paper
• Germ cell migration and early development of the gonads in the trisomy 16 mouse--an animal model for Down's syndrome.

  1999cited by this paper
• Neuronal Apoptosis in Mouse Trisomy 16

  1999cited by this paper
• Altered Ca2+ Signaling and Mitochondrial Deficiencies in Hippocampal Neurons of Trisomy 16 Mice: A Model of Down’s Syndrome

  1998cited by this paper
• Altered Ca 2 1 Signaling and Mitochondrial Deficiencies in Hippocampal Neurons of Trisomy 16 Mice : A Model of Down ’ s Syndrome

  1998cited by this paper
• A mouse model for Down syndrome exhibits learning and behaviour deficits

  1995cited by this paper
• Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn‐superoxide dismutase: implications for Down syndrome.

  1995cited by this paper
• Hematopoietic cells from mice deficient in wild-type p53 are more resistant to induction of apoptosis by some agents.

  1993cited by this paper
• Stem cell deficiencies and thymic abnormalities in fetal mouse trisomy 16

  1985cited by this paper

• Down syndrome-associated leukaemias: current evidence and challenges

  2024cites this paper
• The aetiology of atypical bone health in individuals with Down syndrome

  2023cites this paper
• Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome

  2020cites this paper
• Rapamycin Treatment Ameliorates Age-Related Accumulation of Toxic Metabolic Intermediates in Brains of the Ts65Dn Mouse Model of Down Syndrome and Aging

  2018cites this paper
• Trans-acting epigenetic effects of chromosomal aneuploidies: lessons from Down syndrome and mouse models

  2016cites this paper
• Metabolomics of Mammalian and Cellular Models of Aging

  2016cites this paper
• Luciano Gaudio A regulatory crosstalk in Down syndrome : competing mRNA-miRNA network

  2015cites this paper
• Circulating Neural and Muscle Progenitor Mononuclear Cells in Blood of Down Syndrome Patients = الخلايا أحادية النواة المهيئة للعضلات و الأعصاب في دم مرضى متلازمة داون

  2015cites this paper
• Markers of neural degeneration and regeneration in Down syndrome patients

  2013cites this paper
• Apoptosis in Down’s syndrome: lessons from studies of human and mouse models

  2013cites this paper
• The Use of Mouse Models for Understanding the Biology of Down Syndrome and Aging

  2012cites this paper
• Hematopoietic progenitors express embryonic stem cell and germ layer genes.

  2011cites this paper
• Massive-Scale RNA-Seq Analysis of Non Ribosomal Transcriptome in Human Trisomy 21

  2011cites this paper
• Altered DNA Methylation in Leukocytes with Trisomy 21

  2010cites this paper
• Impairment of circulating endothelial progenitors in Down syndrome

  2010cites this paper
• Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome.

  2009cites this paper
• Highly penetrant myeloproliferative disease in the Ts65Dn mouse model of Down syndrome.

  2008cites this paper
• Defective proliferative capacity and accelerated telomeric loss of hematopoietic progenitor cells in rheumatoid arthritis.

  2008cites this paper