Untargeted Metabolomics Analysis of ABCC6-Deficient Mice Discloses an Altered Metabolic Liver Profile.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Journal of Proteome Research

• Publication date

  2016-11-03

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/ACS.JPROTEOME.6B00669PMID 27758107
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Research Progress in Pseudoxanthoma Elasticum and Related Ectopic Mineralization Disorders

  2015cited by this paper
• Dysregulation of gene expression in ABCC6 knockdown HepG2 cells

  2014cited by this paper
• ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report

  2014cited by this paper
• Large-Scaled Metabolic Profiling of Human Dermal Fibroblasts Derived from Pseudoxanthoma Elasticum Patients and Healthy Controls

  2014cited by this paper
• The level of hepatic ABCC6 expression determines the severity of calcification after cardiac injury.

  2014cited by this paper
• Is classical pseudoxanthoma elasticum a consequence of hepatic ‘intoxication’ due to ABCC6 substrate accumulation in the liver?

  2013cited by this paper
• ABCC6 Is a Basolateral Plasma Membrane Protein

  2013cited by this paper
• ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release

  2013cited by this paper
• The Vesicular Transport Assay: Validated In Vitro Methods to Study Drug‐Mediated Inhibition of Canalicular Efflux Transporters ABCB11/BSEP and ABCC2/MRP2

  2012cited by this paper
• The molecular and physiological roles of ABCC6: more than meets the eye

  2012cited by this paper
• ABCC6 Localizes to the Mitochondria-Associated Membrane

  2012cited by this paper
• ABCG2 functions as a general phytoestrogen sulfate transporter in vivo

  2012cited by this paper
• Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays

  2012cited by this paper
• CAMERA: an integrated strategy for compound spectra extraction and annotation of liquid chromatography/mass spectrometry data sets.

  2012cited by this paper
• ABCC6 does not transport vitamin K3-glutathione conjugate from the liver: relevance to pathomechanisms of pseudoxanthoma elasticum.

  2011cited by this paper
• ABCC6 does not transport adenosine - relevance to pathomechanism of pseudoxanthoma elasticum.

  2011cited by this paper
• Vitamin K does not prevent soft tissue mineralization in a mouse model of pseudoxanthoma elasticum

  2011cited by this paper
• Vitamin K supplementation increases vitamin K tissue levels but fails to counteract ectopic calcification in a mouse model for pseudoxanthoma elasticum

  2011cited by this paper
• Expression and In Vivo Rescue of Human ABCC6 Disease-Causing Mutants in Mouse Liver

  2011cited by this paper
• Administration of vitamin K does not counteract the ectopic mineralization of connective tissues in Abcc6-/- mice, a model for pseudoxanthoma elasticum

  2011cited by this paper
• Technical and biological variation in UPLC-MS-based untargeted metabolic profiling of liver extracts: application in an experimental toxicity study on galactosamine.

  2011cited by this paper
• Parabiotic heterogenetic pairing of Abcc6-/-/Rag1-/- mice and their wild-type counterparts halts ectopic mineralization in a murine model of pseudoxanthoma elasticum.

  2010cited by this paper
• Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts

  2009cited by this paper
• Pseudoxanthoma elasticum is a metabolic disease.

  2009cited by this paper
• N-acetylamino acid utilization by kidney aminoacylase-1.

  2008cited by this paper
• Highly sensitive feature detection for high resolution LC/MS

  2008cited by this paper
• XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification.

  2006cited by this paper
• Chromatographic alignment of ESI-LC-MS proteomics data sets by ordered bijective interpolated warping.

  2006cited by this paper
• Tissue-specific expression of the ABCC6 gene.

  2005cited by this paper
• Disruption of Abcc6 in the mouse: novel insight in the pathogenesis of pseudoxanthoma elasticum.

  2005cited by this paper
• Targeted Ablation of the Abcc6 Gene Results in Ectopic Mineralization of Connective Tissues

  2005cited by this paper
• MRP6 (ABCC6) Detection in Normal Human Tissues and Tumors

  2002cited by this paper
• Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6).

  2002cited by this paper
• Loss of ATP-dependent Transport Activity in Pseudoxanthoma Elasticum-associated Mutants of Human ABCC6 (MRP6)*

  2002cited by this paper
• Molecular genetics of pseudoxanthoma elasticum: a metabolic disorder at the environment-genome interface?

  2001cited by this paper
• Mutations in ABCC6 cause pseudoxanthoma elasticum

  2000cited by this paper
• Pseudoxanthoma elasticum: mutations in the MRP6 gene encoding a transmembrane ATP-binding cassette (ABC) transporter.

  2000cited by this paper
• Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum

  2000cited by this paper
• Mutations of the gene encoding the transmembrane transporter protein ABC-C6 cause pseudoxanthoma elasticum

  2000cited by this paper
• Purine catabolism: links to mitochondrial respiration and antioxidant defenses?

  1999cited by this paper
• Identification and determination of succinyladenosine in human cerebrospinal fluid.

  1999cited by this paper
• MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver

  1999cited by this paper
• Human and porcine aminoacylase I overproduced in a baculovirus expression vector system: evidence for structural and functional identity with enzymes isolated from kidney.

  1998cited by this paper
• Segmental distribution of the endocytosis receptor gp330 in renal proximal tubules.

  1995cited by this paper
• Investigation of urea cycle enzyme disorders by 1H-NMR spectroscopy.

  1992cited by this paper

• Application of Weighted Gene Co-Expression Network Analysis to Metabolomic Data from an ApoA-I Knockout Mouse Model

  2024cites this paper
• The Purinergic Nature of Pseudoxanthoma Elasticum

  2024cites this paper
• Current Knowledge in Skin Metabolomics: Updates from Literature Review

  2022cites this paper
• From membrane to mineralization: the curious case of the ABCC6 transporter

  2020cites this paper
• Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum.

  2018cites this paper
• ABCC6 knockdown in HepG2 cells induces a senescent-like cell phenotype

  2017cites this paper
• Pseudoxanthoma elasticum

  2017cites this paper