The Urocortins: mechanisms of cardioprotection and therapeutic potential.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Mini-Reviews in Medical Chemistry

• Publication date

  2006-09-30

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.2174/138955706778560111PMID 17073712
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Protective effects of the urocortin homologues stresscopin (SCP) and stresscopin-related peptide (SRP) against hypoxia/reoxygenation injury in rat neonatal cardiomyocytes.

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• Protein Kinase C&egr; Interacts With and Inhibits the Permeability Transition Pore in Cardiac Mitochondria

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• KATP Channel Gene Expression Is Induced by Urocortin and Mediates Its Cardioprotective Effect

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• The Phosphatidylinositol 3-Kinase (PI3K)-Akt Pathway Suppresses Bax Translocation to Mitochondria*

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• Urocortin increases the expression of heat shock protein 90 in rat cardiac myocytes in a MEK1/2-dependent manner.

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• Targeted disruption of the protein kinase C epsilon gene abolishes the infarct size reduction that follows ischaemic preconditioning of isolated buffer-perfused mouse hearts.

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• Activation of protein kinase B/Akt by urocortin is essential for its ability to protect cardiac cells against hypoxia/reoxygenation-induced cell death.

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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  2009cites this paper
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