Peptidyl-Prolyl Isomerase 1 (Pin1) Serves as a Coactivator of Steroid Receptor by Regulating the Activity of Phosphorylated Steroid Receptor Coactivator 3 (SRC-3/AIB1)

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Molecular and Cellular Biology

• Publication date

  2005-11-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/MCB.25.21.9687-9699.2005PMID 16227615PMCID PMC1265806
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Concomitant Increase of Histone Acetyltransferase Activity and Degradation of p300 during Retinoic Acid-induced Differentiation of F9 Cells*

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• Spermatogonial Depletion in Adult Pin1-Deficient Mice1

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• Peptide Binding Induces Large Scale Changes in Inter-domain Mobility in Human Pin1*

  2003cited by this paper
• Role of the Steroid Receptor Coactivator SRC-3 in Cell Growth

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• Pin1 regulates the timing of mammalian primordial germ cell proliferation

  2003cited by this paper
• Progesterone and Glucocorticoid Receptors Recruit Distinct Coactivator Complexes and Promote Distinct Patterns of Local Chromatin Modification

  2003cited by this paper
• Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA.

  2003cited by this paper
• Pin1 modulates the structure and function of human RNA polymerase II.

  2003cited by this paper
• Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling.

  2003cited by this paper
• Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator Activity by IκB Kinase

  2002cited by this paper
• Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes

  2002cited by this paper
• Role of Pin1 in the Regulation of p53 Stability and p21 Transactivation, and Cell Cycle Checkpoints in Response to DNA Damage*

  2002cited by this paper
• The prolyl isomerase Pin1 is a regulator of p53 in genotoxic response

  2002cited by this paper
• Suppression of Androgen Receptor Transactivation by Pyk2 via Interaction and Phosphorylation of the ARA55 Coregulator*

  2002cited by this paper
• Functional Interaction of STAT3 Transcription Factor with the Coactivator NcoA/SRC1a*

  2002cited by this paper
• Steroid Receptor Coactivator-3 Is Required for Inhibition of Neointima Formation by Estrogen

  2002cited by this paper
• Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.

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• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

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• Pin1 regulates turnover and subcellular localization of beta-catenin by inhibiting its interaction with APC.

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• Pin1 regulates turnover and subcellular localization of β-catenin by inhibiting its interaction with APC

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• Pin1 is overexpressed in breast cancer and cooperates with Ras signaling in increasing the transcriptional activity of c‐Jun towards cyclin D1

  2001cited by this paper
• Phosphorylation of RNA polymerase II CTD fragments results in tight binding to the WW domain from the yeast prolyl isomerase Ess1.

  2001cited by this paper
• Ribozyme Targeting Demonstrates That the Nuclear Receptor Coactivator AIB1 Is a Rate-limiting Factor for Estrogen-dependent Growth of Human MCF-7 Breast Cancer Cells*

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• Pin1 acts catalytically to promote a conformational change in Cdc25.

  2001cited by this paper
• Prolyl isomerases.

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• FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent.

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• The 26S Proteasome Is Required for Estrogen Receptor-α and Coactivator Turnover and for Efficient Estrogen Receptor-α Transactivation

  2000cited by this paper
• Regulation of somatic growth by the p160 coactivator p/CIP.

  2000cited by this paper
• Structural basis for phosphoserine-proline recognition by group IV WW domains

  2000cited by this paper
• The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development.

  2000cited by this paper
• Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins.

  2000cited by this paper
• The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation.

  2000cited by this paper
• AIB1 Is a Conduit for Kinase-Mediated Growth Factor Signaling to the Estrogen Receptor

  2000cited by this paper
• Requirement of the prolyl isomerase Pin1 for the replication checkpoint.

  2000cited by this paper
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  1999cited by this paper
• Steroid receptor coactivator-1 and its family members differentially regulate transactivation by the tumor suppressor protein p53.

  1999cited by this paper
• Regulation of transcription by a protein methyltransferase.

  1999cited by this paper
• The mitotic peptidyl‐prolyl isomerase, Pin1, interacts with Cdc25 and Plx1

  1998cited by this paper
• Steroid Receptor Coactivator-1 Interacts with Serum Response Factor and Coactivates Serum Response Element-mediated Transactivations*

  1998cited by this paper
• Transcription factor-specific requirements for coactivators and their acetyltransferase functions.

  1998cited by this paper
• Histone acetyltransferase activity of CBP is controlled by cycle-dependent kinases and oncoprotein E1A

  1998cited by this paper
• A Transcriptional Coactivator, Steroid Receptor Coactivator-3, Selectively Augments Steroid Receptor Transcriptional Activity*

  1998cited by this paper
• Structure and specificity of nuclear receptor-coactivator interactions.

  1998cited by this paper
• TRAM-1, A Novel 160-kDa Thyroid Hormone Receptor Activator Molecule, Exhibits Distinct Properties from Steroid Receptor Coactivator-1*

  1997cited by this paper
• AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer.

  1997cited by this paper
• All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiae.

  1997cited by this paper
• The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

  1997cited by this paper
• Structural and Functional Analysis of the Mitotic Rotamase Pin1 Suggests Substrate Recognition Is Phosphorylation Dependent

  1997cited by this paper
• Nuclear receptor coactivator ACTR is a novel histone acetyltransferase and forms a multimeric activation complex with P/CAF and CBP/p300.

  1997cited by this paper
• RAC3, a steroid/nuclear receptor-associated coactivator that is related to SRC-1 and TIF2.

  1997cited by this paper
• GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.

  1996cited by this paper
• A human peptidyl–prolyl isomerase essential for regulation of mitosis

  1996cited by this paper
• TIF2, a 160 kDa transcriptional mediator for the ligand‐dependent activation function AF‐2 of nuclear receptors.

  1996cited by this paper
• A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors.

  1996cited by this paper
• Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

  1995cited by this paper
• Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily

  1995cited by this paper

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• Changes in Estrogen Receptor Alpha (ERα) Phosphorylation in Human T Cells

  2015cites this paper
• Pin1-based diagnostic and therapeutic strategies for breast cancer.

  2015cites this paper
• Peptidylprolyl Isomerase Pin1 Directly Enhances the DNA Binding Functions of Estrogen Receptor α*

  2015cites this paper
• Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast by counteracting the Fbxw7-oncosuppressive barrier on the Notch signalling pathway

  2014cites this paper
• Prolyl isomerase Pin1 in cancer

  2014cites this paper
• Nuclear receptor modulation--role of coregulators in selective estrogen receptor modulator (SERM) actions.

  2014cites this paper
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  2014cites this paper
• Transcriptional coregulators: emerging roles of SRC family of coactivators in disease pathology.

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• HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop.

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• Pin1 Null Mice Exhibit Low Bone Mass and Attenuation of BMP Signaling

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• Prolyl isomerase Pin1 negatively regulates the stability of SUV39H1 to promote tumorigenesis in breast cancer

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• AIB1: A Transcriptional Coactivator Which Integrates Signaling Cross Talk in Cancer Cells

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  2012cites this paper
• Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.

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• Prolyl isomerase Pin1 down-regulates tumor suppressor RUNX3 in breast cancer

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