The dynein cortical anchor Num1 activates dynein motility by relieving Pac1/LIS1-mediated inhibition

Upon offloading to Num1 cortical receptor sites in budding yeast, cytoplasmic dynein motility is switched “on” by a mechanism that likely involves Num1-mediated dissociation of the Pac1 inhibitor, a homologue of human LIS1.

• Publication year

  2015

• Venue

  Journal of Cell Biology

• Publication date

  2015-10-26

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.201506119PMID 26483554PMCID 4621840
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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