Translocation of Active Heparanase to Cell Surface Regulates Degradation of Extracellular Matrix Heparan Sulfate upon Transmigration of Mature Monocyte-Derived Dendritic Cells1

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Immunology

• Publication date

  2006-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4049/jimmunol.176.11.6417PMID 16709798
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Modulation of the Heparanase-inhibiting Activity of Heparin through Selective Desulfation, Graded N-Acetylation, and Glycol Splitting*

  2005cited by this paper
• Processing and activation of latent heparanase occurs in lysosomes

  2004cited by this paper
• Prostaglandin E2-Dependent Enhancement of Tissue Inhibitors of Metalloproteinases-1 Production Limits Dendritic Cell Migration through Extracellular Matrix1

  2004cited by this paper
• Human heparanase nuclear localization and enzymatic activity

  2004cited by this paper
• Cell Surface Localization of Heparanase on Macrophages Regulates Degradation of Extracellular Matrix Heparan Sulfate1

  2004influential reference
• Heparanase Uptake Is Mediated by Cell Membrane Heparan Sulfate Proteoglycans*

  2004cited by this paper
• Factors and signals that govern the migration of dendritic cells via lymphatics: recent advances

  2004cited by this paper
• Biochemical characterization of the active heterodimer form of human heparanase (Hpa1) protein expressed in insect cells.

  2003cited by this paper
• Heterodimer formation is essential for heparanase enzymatic activity.

  2003cited by this paper
• Heparanase Expression Correlates with Invasion and Poor Prognosis in Gastric Cancers

  2003cited by this paper
• Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis

  2002cited by this paper
• Measurement of nuclear factor-kappa B translocation on lipopolysaccharide-activated human dendritic cells by confocal microscopy and flow cytometry.

  2002cited by this paper
• Matrix Metalloproteinases 9 and 2 Are Necessary for the Migration of Langerhans Cells and Dermal Dendritic Cells from Human and Murine Skin1

  2002cited by this paper
• Opsonization of Apoptotic Cells by Autologous iC3b Facilitates Clearance by Immature Dendritic Cells, Down-regulates DR and CD86, and Up-regulates CC Chemokine Receptor 7

  2002cited by this paper
• Heparanase: a key enzyme involved in cell invasion.

  2001cited by this paper
• Expression Pattern and Secretion of Human and Chicken Heparanase Are Determined by Their Signal Peptide Sequence*

  2001cited by this paper
• Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis.

  2001cited by this paper
• Purification and characterization of the endoglycosidase heparanase 1 from human plantar stratum corneum: a key enzyme in epidermal physiology?

  2001cited by this paper
• Heparanase, a potential regulator of cell-matrix interactions.

  2000cited by this paper
• Chemokines and Dendritic Cell Traffic

  2000cited by this paper
• Extracellular matrix moieties, cytokines, and enzymes: dynamic effects on immune cell behavior and inflammation

  2000cited by this paper
• Mammalian heparanase: Gene cloning, expression and function in tumor progression and metastasis

  1999cited by this paper
• CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs.

  1999cited by this paper
• Processing of the Human Heparanase Precursor and Evidence That the Active Enzyme Is a Heterodimer*

  1999cited by this paper
• Preparation of Extracellular Matrices Produced by Cultured Corneal Endothelial and PF‐HR9 Endodermal Cells

  1999cited by this paper
• Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation

  1998cited by this paper
• Treatment of central nervous system inflammation with inhibitors of basement membrane degradation

  1998cited by this paper
• Human platelet heparanase: purification, characterization and catalytic activity.

  1998cited by this paper
• Dendritic cells and the control of immunity

  1998cited by this paper
• EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation.

  1998cited by this paper
• Adhesion, transendothelial migration, and reverse transmigration of in vitro cultured dendritic cells.

  1998cited by this paper
• Selective Recruitment of Immature and Mature Dendritic Cells by Distinct Chemokines Expressed in Different Anatomic Sites

  1998cited by this paper
• Comparative analysis of the ability of leucocytes, endothelial cells and platelets to degrade the subendothelial basement membrane: Evidence for cytokine dependence and detection of a novel sulfatase

  1995cited by this paper
• Immunol. Cell Biol.

  1995cited by this paper
• Inhibition of tumor metastasis by heparanase inhibiting species of heparin.

  1994cited by this paper
• Expression of heparanase by platelets and circulating cells of the immune system: possible involvement in diapedesis and extravasation.

  1992cited by this paper
• Inhibition of T lymphocyte heparanase by heparin prevents T cell migration and T cell‐mediated immunity

  1990cited by this paper
• Heparanases and tumor metastasis

  1988cited by this paper
• Soluble antigen induces T lymphocytes to secrete an endoglycosidase that degrades the heparan sulfate moiety of subendothelial extracellular matrix

  1987cited by this paper
• Involvement of both heparanase and plasminogen activator in lymphoma cell‐mediated degradation of heparan sulfate in the subendothelial extracellular matrix

  1986cited by this paper
• Lymphoma cell-mediated degradation of sulfated proteoglycans in the subendothelial extracellular matrix: relationship to tumor cell metastasis.

  1983cited by this paper

• NK cell heparanase controls tumor invasion and immune surveillance

  2024cites this paper
• Extracellular matrix remodeling in the tumor immunity

  2024cites this paper
• Heparanase promotes the onset and progression of atherosclerosis in apolipoprotein E gene knockout mice.

  2024cites this paper
• Heparanase in Acute Pancreatitis.

  2020cites this paper
• Heparanase is Involved in Leukocyte Migration.

  2020cites this paper
• Role of Heparanase in tumor progression: molecular aspects and therapeutic options.

  2020cites this paper
• Role of Heparanase in Macrophage Activation.

  2020cites this paper
• Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression

  2019cites this paper
• Heparanase: A Challenging Cancer Drug Target

  2019cites this paper
• The Role of Heparan Sulfate in Inflammation, and the Development of Biomimetics as Anti-Inflammatory Strategies

  2018cites this paper
• Heparan sulfate is a plasma biomarker of acute cellular allograft rejection

  2018cites this paper
• NK cell heparanase controls tumor invasion and immune surveillance

  2017cites this paper
• Heparanase regulation of cancer, autophagy and inflammation: new mechanisms and targets for therapy

  2017cites this paper
• The Role of Heparanase in the Pathogenesis of Acute Pancreatitis: A Potential Therapeutic Target

  2017cites this paper
• Heparanase: From basic research to therapeutic applications in cancer and inflammation.

  2016cites this paper
• Migration of dendritic cells to the lymph nodes and its enhancement to drive anti-tumor responses.

  2016cites this paper
• Cell surface proteoglycans control astrocyte migration and retinal angiogenesis by regulating basement membrane assembly

  2015cites this paper
• The Role of Heparanase in Pulmonary Cell Recruitment in Response to an Allergic but Not Non-Allergic Stimulus

  2015cites this paper
• Novel role for heparan sulfate in thymic development of CD8⁺ T lymphocytes

  2015cites this paper
• Heparanase of murine effector lymphocytes and neutrophils is not required for their diapedesis into sites of inflammation

  2015cites this paper
• Heparan sulphate as a regulator of leukocyte recruitment in inflammation.

  2015cites this paper
• Vascular Endothelial Growth Factor C/Vascular Endothelial Growth Factor Receptor 3 Signaling Regulates Chemokine Gradients and Lymphocyte Migration From Tissues to Lymphatics

  2015cites this paper
• Heparanase expression in Langerhans cell histiocytosis

  2014cites this paper
• Modification of heparanase gene expression in response to conditioning and LPS treatment: strong correlation to rs4693608 SNP

  2014cites this paper
• Mice deficient in heparanase exhibit impaired dendritic cell migration and reduced airway inflammation

  2014cites this paper
• Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury.

  2014cites this paper
• Heparanase and Autoimmune Diabetes

  2013cites this paper
• Heparan Sulfate: A Ubiquitous Glycosaminoglycan with Multiple Roles in Immunity

  2013cites this paper
• In vitro and ex vivo evaluation of a multi-epitope heparinase vaccine for various malignancies

  2013cites this paper
• Unexpected new roles for heparanase in Type 1 diabetes and immune gene regulation.

  2013cites this paper
• Versatile role of heparanase in inflammation.

  2013cites this paper
• Dissociation between Mature Phenotype and Impaired Transmigration in Dendritic Cells from Heparanase-Deficient Mice

  2012influential citation
• Heparanase enzyme in chronic inflammatory bowel disease and colon cancer

  2012cites this paper
• Electric signals regulated immunomodulation and wound healing

  2012cites this paper
• The role of histidine-rich glycoprotein in necrotic cell clearance and regulation of degradative enzymes

  2011cites this paper
• Bovine dendritic cells & their interaction with E.coli 0157:H7

  2011cites this paper
• Heparanase expression in head and neck squamous cell carcinomas is associated with reduced proliferation and improved survival

  2011cites this paper
• Heparanase upregulates Th2 cytokines, ameliorating experimental autoimmune encephalitis.

  2010cites this paper
• Histidine-rich glycoprotein binds heparanase and regulates its enzymatic activity and cell surface interactions.

  2010cites this paper
• Wound Healing Versus Regeneration: Role of the Tissue Environment in Regenerative Medicine

  2010cites this paper
• Accumulation of Ym1 and formation of intracellular crystalline bodies in alveolar macrophages lacking heparanase.

  2010cites this paper
• Heparan sulfate proteoglycans in extravasation: assisting leukocyte guidance.

  2009cites this paper
• A influência do fator de crescimento endotelial vascular na maturação "in vitro" de células dendríticas derivadas de monócitos

  2008cites this paper
• H-2Kb-restricted CTL epitopes from mouse heparanase elicit an antitumor immune response in vivo.

  2008cites this paper
• Heparanase-2, syndecan-1, and extracellular matrix remodeling in colorectal carcinoma

  2008cites this paper
• Heparanase expression in B16 melanoma cells and peripheral blood neutrophils before and after extravasation detected by novel anti-mouse heparanase monoclonal antibodies.

  2008cites this paper
• Cell Surface-expressed Cation-independent Mannose 6-Phosphate Receptor (CD222) Binds Enzymatically Active Heparanase Independently of Mannose 6-Phosphate to Promote Extracellular Matrix Degradation*

  2008cites this paper
• HLA-A2-restricted cytotoxic T lymphocyte epitopes from human heparanase as novel targets for broad-spectrum tumor immunotherapy.

  2008cites this paper
• Dramatic regulation of heparanase activity and angiogenesis gene expression in synovium from patients with rheumatoid arthritis.

  2008cites this paper
• Mammalian heparanase: what is the message?

  2007cites this paper
• Inflammation et infiltration monocytaire associées à la dégénérescence neuronale induite par un status epilepticus chez le rat

  2007cites this paper
• Current World Literature

  2007cites this paper
• Heparanase: a target for drug discovery in cancer and inflammation

  2007cites this paper
• Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1.

  2007cites this paper
• Dendritic Cells Reconstituted with a Human Heparanase Gene Induce Potent Cytotoxic T-Cell Responses against Gastric Tumor Cells in vitro

  2007cites this paper
• Expression of the heparan sulfate‐degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene

  2007cites this paper
• Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma.

  2006cites this paper
• World Journal of Experimental Medicine

  year unknowncites this paper