Uninvolved skin from psoriatic patients develops signs of involved psoriatic skin after being grafted onto nude mice.

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Science

• Publication date

  1982-02-05

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1126/SCIENCE.7036342PMID 7036342
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Normal and psoriatic human skin grafts on "nude" mice: morphological and immunochemical studies.

  1981cited by this paper
• A simple, rapid, and sensitive DNA assay procedure.

  1980cited by this paper
• Abnormal proliferation of uninvolved psoriatic epidermis: differential induction by saline, propranolol, and tape stripping in vivo.

  1979cited by this paper
• Epidermal activity in the involved and uninvolved skin of patients with psoriasis

  1978cited by this paper
• Cyclic AMP accumulation in psoriatic skin: differential responses to histamine, AMP, and einephrine by the uninvolved and involved epidermis.

  1978cited by this paper
• Determination of glycolic acid by the Eegriwe (Calkins) method: Interference by ethylenediaminetetraacetic acid and formaldehyde

  1977cited by this paper
• Secretion of plasminogen activator by rheumatoid and nonrheumatoid synovial cells in culture.

  1977cited by this paper
• Human skin proteases

  1976cited by this paper
• Plasminogen activator and histone hydrolyzing proteases in psoriasis scales--possible role in increased cell division.

  1976cited by this paper
• Long-term maintenance of psoriatic human skin on congenitally athymic (nude) mice.

  1975cited by this paper
• [Letter: Deficit of T-lymphocytes in psoriasis].

  1975cited by this paper
• Increased concentrations of nonesterified arachidonic acid, 12L-hydroxy-5,8,10,14-eicosatetraenoic acid, prostaglandin E2, and prostaglandin F2alpha in epidermis of psoriasis.

  1975cited by this paper
• Inhibitors of fibrinolysis in human tissues in culture.

  1971cited by this paper
• Microassay for cathepsin D shows an unexpected effedt of cycloheximide on limb-bone rudiments in organ culture.

  1970cited by this paper
• Abnormal cell proliferation in psoriasis.

  1968cited by this paper
• [Fibrinolytic activity of the skin in psoriasis and various other dermatoses].

  1967cited by this paper
• Autoradiographic analysis of turnover times of normal and psoriatic epidermis.

  1965cited by this paper
• KINETICS OF HYPERPLASIA IN PSORIASIS.

  1963cited by this paper
• The polymerization of proteins; the action of thrombin on fibrinogen.

  1951cited by this paper

• RNA-Based Antipsoriatic Gene Therapy: An Updated Review Focusing on Evidence from Animal Models

  2024cites this paper
• The Experimental Animal Models in Psoriasis Research: A Comprehensive Review.

  2023cites this paper
• Mouse Models of Psoriasis: A Comprehensive Review.

  2021cites this paper
• New Frontiers in Psoriatic Disease Research, Part I: Genetics, Environmental Triggers, Immunology, Pathophysiology, and Precision Medicine.

  2021cites this paper
• Animal models of psoriasis-highlights and drawbacks.

  2020cites this paper
• FIH‐1 engages novel binding partners to positively influence epithelial proliferation via p63

  2019cites this paper
• What's New in Psoriasis.

  2019cites this paper
• Murine models of psoriasis and its applications in drug development.

  2019cites this paper
• Mechanisms of resident T cell-driven tissue responses during the onset and recurrence of human skin inflammation

  2019cites this paper
• The Role of Purinergic Signalling in Inflammatory Disorders

  2019cites this paper
• Murine models of psoriasis and their usefulness for drug discovery

  2018cites this paper
• Models in the Research Process of Psoriasis

  2017cites this paper
• RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin

  2017cites this paper
• Reduction in tissue plasmin: a new mechanism of action of narrowband ultraviolet B in psoriasis

  2015cites this paper
• Plasmin Plays an Essential Role in Amplification of Psoriasiform Skin Inflammation in Mice

  2011influential citation
• Animal models of psoriasis: a critical appraisal

  2008cites this paper
• Animal models of psoriasis.

  2007cites this paper
• Mouse models of psoriasis.

  2007cites this paper
• Decreased specific anti-elastase activity in the uninvolved skin of patients with psoriasis

  2005cites this paper
• Basement membrane zone as a target for human neutrophil elastase in psoriasis

  2004cites this paper
• Histologic characteristics of lichen planus transplanted onto nude mice and cultured in vitro

  2004cites this paper
• Increased expression of adhesion receptors in both lesional and non-lesional psoriatic skin

  2004cites this paper
• Interleukin-6 in psoriasis: expression and mitogenicity studies

  2004cites this paper
• Vaginocervical stimulation-induced release of classical neurotransmitters and nitric oxide in the nucleus of the solitary tract varies as a function of the oestrus cycle.

  2001cites this paper
• Basement membrane alterations in psoriasis are accompanied by epidermal overexpression of MMP-2 and its inhibitor TIMP-2.

  2000cites this paper
• Expert Opinion on Investigational Drugs

  1999cites this paper
• Animal models of psoriasis - what can we learn from them?

  1999cites this paper
• Animal models of psoriasis.

  1999cites this paper
• Human Psoriatic Skin in Organ Culture: Comparison with Normal Skin Exposed to Exogenous Growth Factors and Effects of an Antibody to the EGF Receptor

  1998cites this paper
• Defined System to Assess the in Vitro Induction of a Psoriasis Phenotype on Normal Keratinocytes by Fibroblasts from Psoriatic Subjects

  1997cites this paper
• Psoriasis- Mediation of Skin Phenotype by Circulatory Pathogenic T Lymphocytes

  1997cites this paper
• T-lymphocyte dependence of psoriatic pathology in human psoriatic skin grafted to SCID mice.

  1997cites this paper
• In vivo effects of cytokines on psoriatic skin grafted on nude mice: involvement of the tumour necrosis factor (TNF) receptor

  1996cites this paper
• Antiproliferative effect of pentoxifylline on psoriatic and normal epidermis. In vitro and in vivo studies.

  1996cites this paper
• Dermal injection of immunocytes induces psoriasis.

  1996cites this paper
• Secretory component (polymeric immunoglobulin receptor) expression on human keratinocytes by stimulation with interferon-gamma and differences in response.

  1996cites this paper
• Pathogenesis of Psoriasis: Current Concepts

  1995cites this paper
• Differentiation of involved and uninvolved psoriatic skin from healthy skin using noninvasive visual, colorimeter and evaporimeter methods

  1995cites this paper
• The nude mouse model for the study of human skin disorders.

  1994cites this paper
• Lipid composition and barrier function of human skin after grafting onto athymic nude mice.

  1994cites this paper
• Comparative analysis of normal and psoriatic skin both in vivo and in vitro.

  1994cites this paper
• Immunohistochemical characterization of the plasminogen activator system in psoriatic epidermis

  1993cites this paper
• Determination of the action spectrum for UV-induced plasminogen activator synthesis in mouse keratinocytes in vitro.

  1992cites this paper
• Psoriasis. I. Pathogenesis.

  1992cites this paper
• Plasminogen Activators in Epithelial Biology

  1991cites this paper
• Genomic, phenotypic, and functional analyses of T cells in patients with psoriasis undergoing systemic cyclosporin A treatment.

  1991cites this paper
• Tissue plasminogen activator in psoriasis.

  1990cites this paper
• Tissue plasminogen activator in psoriasis.

  1990cites this paper
• Beta‐adrenergic stimulation of cyclic AMP is defective in cultured dermal fibroblasts of psoriatic subjects

  1990cites this paper
• Fibrinolysis and Fibrinolytic Drugs

  1989cites this paper
• A novel histone-stimulated protein kinase in normal and psoriatic epidermis.

  1989cites this paper
• Purification and characterization of recombinant tuna growth hormone produced in Escherichia coli

  1989cites this paper
• Keratinocyte urokinase-type plasminogen activator is secreted as a single chain precursor.

  1988cites this paper
• Trends in protease inhibition.

  1988cites this paper
• Benzo[a]pyrene diol epoxide I modification of DNA in human skin xenografts.

  1988cites this paper
• Psoriasis: In vivo models for topical drug evaluation

  1988cites this paper
• Epidermal plasminogen activator is abnormal in cutaneous lesions.

  1988cites this paper
• Immunohistochemical localization of urokinase- and tissue-type plasminogen activators in psoriatic skin.

  1987cites this paper
• Plasminogen activator secreted by cultured human melanocytes

  1986cites this paper
• Human cutaneous nevi transplanted onto nude mice: a model for the study of the lesional steps in tumor progression.

  1986cites this paper
• Secretion of plasminogen activator inhibitor by cultured human epidermal cells

  1986cites this paper
• Plasminogen activators, tissue degradation, and cancer.

  1985cites this paper
• Proteinases and psoriasis.

  1985cites this paper
• Research models for psoriasis.

  1985cites this paper
• Characterization and activity of phospholipase A2 in normal human epidermis and in lesion‐free epidermis of patients with psoriasis or eczema

  1985cites this paper
• Human epidermal plasminogen activator. Characterization, localization, and modulation.

  1985cites this paper
• Clinically uninvolved skin in psoriasis.

  1985cites this paper
• Plasminogen activator in psoriatic scales is of the tissue‐type PA as identified by monoclonal antibodies

  1985cites this paper
• Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors.

  1985cites this paper
• Tissue plasminogen activator inhibitor in the epidermis

  1985cites this paper
• Human skin grafts on athymic nude rats. An experimental model for dermatological research.

  1984cites this paper
• Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes

  1984cites this paper
• Effect of polyamine antimetabolites on cultured human keratinocytes from normal and uninvolved psoriatic skin

  1984cites this paper
• Alpha 1-antitrypsin deficiency genes: contributory defect in a subset of psoriatics?

  1984cites this paper
• Molecular size of secreted and cell‐associated plasminogen activators from cultured epidermal cells

  1983cites this paper
• Transplantation of psoriatic skin onto nude mice.

  1983cites this paper
• Plasminogen is present in the basal layer of the epidermis.

  1983cites this paper
• Transplantation of Psoriatic Skin onto Nude Mice.

  1983cites this paper
• Human skin proteinases as inflammatory mediators.

  1983cites this paper
• Correlation of epidermal plasminogen activator activity with disease activity in psoriasis

  1983cites this paper
• Plasminogen activator in cultured human epidermal cells.

  1983cites this paper
• Commentary: Cyclic Adenosine Monophosphate Regulation of Normal and Psoriatic Epidermis

  1982cites this paper
• Positron Tomography and Nuclear Magnetic Resonance Imaging

  1982cites this paper