New models of lymphoma in transgenic mice.

We are in a 'golden age' of mouse genetics. Genetic engineering and micromanipulation techniques now allow not only the overexpression or misexpression of transgenes randomly inserted into the mouse genome, but also the directed homologous replacement of normal genes with transgenes coding for null or mutant alleles (gene 'knockouts'). Both of these approaches have been used in the past 1-2 years to illuminate the contributions of novel oncogenes and of anti-oncogenes to the molecular basis of lymphomagenesis.

• Publication year

  1995

• Venue

  Current Opinion in Immunology

• Publication date

  1995-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/0952-7915(95)80075-1PMID 8573310
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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