Effect of nicotinic acid-induced insulin resistance on pancreatic B cell function in normal and streptozocin-treated baboons.

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Journal of Clinical Investigation

• Publication date

  1991-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI115145PMID 1826300PMCID PMC295182
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The effect of nicotinic acid on the plasma free fatty acid; demonstration of a metabolic type of sympathicolysis.

  2009cited by this paper
• Glucose tolerance and plasma insulin in man during acute and chronic administration of nicotinic acid.

  2009cited by this paper
• Inducement by Fat Feeding of Basal Hyperglycemia in Rats With Abnormal β-Cell Function: Model for Study of Etiology and Pathogenesis of NIDDM

  1990cited by this paper
• Nonprogression of Subclinical β-Cell Dysfunction Among First-Degree Relatives of IDDM Patients: 5-Yr Follow-Up of the Seattle Family Study

  1990cited by this paper
• A randomized trial of intensive insulin therapy in newly diagnosed insulin-dependent diabetes mellitus.

  1989cited by this paper
• Increased beta-cell secretory capacity as mechanism for islet adaptation to nicotinic acid-induced insulin resistance.

  1989cited by this paper
• Glucose Homeostasis and Insulin Secretion During Chronic Treatment With Cyclosporin in Nondiabetic Humans

  1989cited by this paper
• Increased β-Cell Secretory Capacity as Mechanism for Islet Adaptation to Nicotinic Acid-Induced Insulin Resistance

  1989cited by this paper
• Defects in β-Cell Function and Insulin Sensitivity in Normoglycemic Streptozocin-Treated Baboons: A Model of Preclinical Insulin-Dependent Diabetes*

  1988cited by this paper
• The Triumvirate: β-Cell, Muscle, Liver: A Collusion Responsible for NIDDM

  1988cited by this paper
• Additive Hypoglycemic Effects of Drugs That Modify Free-Fatty Acid Metabolism by Different Mechanisms in Rats With Streptozocin-Induced Diabetes

  1988cited by this paper
• Defects in beta-cell function and insulin sensitivity in normoglycemic streptozocin-treated baboons: a model of preclinical insulin-dependent diabetes.

  1988cited by this paper
• Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp.

  1987cited by this paper
• Modified protocols improve insulin sensitivity estimation using the minimal model.

  1987cited by this paper
• Is insulin-dependent diabetes mellitus a preventable disease?

  1987cited by this paper
• β-Cell Function and Insulin Sensitivity in Nondiabetic HLA-identical Siblings of Insulin-Dependent Diabetics

  1987cited by this paper
• The Insulin Sensitivity Index in Nondiabetic Man: Correlation Between Clamp-derived and IVGTT-derived Values

  1986cited by this paper
• Hyperglycaemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance: implications for the management of diabetes

  1985cited by this paper
• The Effect of Insulin Treatment on Insulin Secretion and Insulin Action in Type II Diabetes Mellitus

  1985cited by this paper
• Differential Sensitivity to β-Cell Secretagogues in “Early,” Type I Diabetes Mellitus

  1984cited by this paper
• Insulin Therapy in Obese, Non-insulin-dependent Diabetes Induces Improvements in Insulin Action and Secretion that Are Maintained for Two Weeks After Insulin Withdrawal

  1984cited by this paper
• Lack of in vivo insulin resistance in controlled insulin-dependent, type I, diabetic patients.

  1984cited by this paper
• Differential sensitivity to beta-cell secretagogues in "early," type I diabetes mellitus.

  1984cited by this paper
• The Insulin Sensitivity Index: Correlation in Dogs Between Values Determined from the Intravenous Glucose Tolerance Test and the Euglycemic Glucose Clamp

  1984cited by this paper
• Reversal of insulin resistance in type I diabetes after treatment with continuous subcutaneous insulin infusion.

  1983cited by this paper
• The defective glucose sensitivity of the B cell in non insulin dependent diabetes. Improvement after twenty hours of normoglycaemia.

  1982cited by this paper
• Glycosylated Hemoglobin in Human and Animal Red Cells: Role of Glucose Permeability

  1982cited by this paper
• Changes in glucose tolerance and plasma insulin during lipid-lowering treatment with diet, clofibrate and niceritrol.

  1982cited by this paper
• Insulin Treatment Reverses the Insulin Resistance of Type II Diabetes Mellitus

  1982cited by this paper
• Effect of corticosterone on insulin and glucagon secretion by the isolated perfused rat pancreas.

  1980cited by this paper
• Comparison of a Colorimetric Assay for Glycosylated Hemoglobin with Ion-exchange Chromatography

  1979cited by this paper
• Paradoxical inhibition of insulin secretion by glucose in human diabetes mellitus.

  1979cited by this paper
• Quantitative estimation of insulin sensitivity.

  1979cited by this paper
• Potentiation of insulin secretory responses by plasma glucose levels in man: evidence that hyperglycemia in diabetes compensates for imparied glucose potentiation.

  1979cited by this paper
• Inhibitory effect of prednisone on insulin secretion in man: model for duplication of blood glucose concentration.

  1975cited by this paper
• The effect of nicotinic acid on growth hormone-induced lipolysis and glucose intolerance.

  1973cited by this paper
• Hyperglucagonism induced by glucocorticoid treatment in man.

  1973cited by this paper
• Acute and steady-state insulin responses to glucose in nonobese diabetic subjects.

  1972cited by this paper
• Oral glucose tolerance, plasma insulin, and uric acid excretion in man during chronic administration of nicotinic acid.

  1971cited by this paper
• Short-term effect of nicotinic acid on plasma level and turnover of free fatty acids in sheep and man.

  1969cited by this paper
• The Effects of 5-Methylpyrazole-3-Carboxylic Acid (U-19,425) and Nicotinic Acid (NA) on Free Fatty Acids (FFA), Triglycerides (TG) and Cholesterol in Man

  1969cited by this paper
• Metabolic Effects of Nicotinic Acid in Acute Insulin Deficiency in the Rat

  1968cited by this paper
• The diabetogenic action of huuan growth hormone: glucose--fatty acid interrelationships.

  1968cited by this paper
• The plasma free fatty acid rebound induced by nicotinic acid.

  1967cited by this paper
• A possible role for the adenylcyclase system in insulin secretion.

  1967cited by this paper
• Insulin secretion in response to glycemic stimulus: relation of delayed initial release to carbohydrate intolerance in mild diabetes mellitus.

  1967cited by this paper
• Biphasic nature of blood glucose and free fatty acid changes following intravenous nicotinic acid in man.

  1967cited by this paper
• Effects of low-carbohydrate diet and diabetes mellitus on plasma concentrations of glucose, non-esterified fatty acid, and insulin during oral glucose-tolerance tests.

  1963cited by this paper
• Immunoassay of Insulin: Two Antibody System: Plasma Insulin Levels of Normal, Subdiabetic and Diabetic Rats

  1963cited by this paper
• The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus.

  1963cited by this paper

• Biological Properties of Vitamins of the B-Complex, Part 1: Vitamins B1, B2, B3, and B5

  2022cites this paper
• Animal models of obesity and diabetes mellitus

  2018cites this paper
• Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field.

  2017cites this paper
• Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets.

  2015cites this paper
• Glycemic control after vitamin D repletion in type 1 diabetes mellitus pediatric population: a clinical trial intervention

  2015cites this paper
• Dosing profile profoundly influences nicotinic acid’s ability to improve metabolic control in rats

  2015cites this paper
• NIACIN AND NIACIN / LAROPIPRANT COMBINATION: OPENING NEW HOPES FOR DYSLIPIDEMIA AND CARDIOVASCULAR DISEASES WITH FEW NOVEL ACTIONS

  2013cites this paper
• HDL functionality and LDL quality : the influence of obesity, obstructive sleep apnoea and pharmacological intervention

  2013cites this paper
• Effects of niacin on glucose levels, coronary stenosis progression, and clinical events in subjects with normal baseline glucose levels (<100 mg/dl): a combined analysis of the Familial Atherosclerosis Treatment Study (FATS), HDL-Atherosclerosis Treatment Study (HATS), Armed Forces Regression Study

  2013cites this paper
• Protective effects of a nicotinamide derivative, isonicotinamide, against streptozotocin-induced β-cell damage and diabetes in mice.

  2013cites this paper
• Extended-release niacin with laropiprant: a review on efficacy, clinical effectiveness and safety

  2012cites this paper
• Immune modulation with amniotic epithelial cells in pancreatic islet transplantation

  2012cites this paper
• Oral nicotinamide reduces serum phosphorus, increases HDL, and induces thrombocytopenia in hemodialysis patients: a double-blind randomized clinical trial.

  2011cites this paper
• Biological and pharmacological roles of HCA receptors.

  2011cites this paper
• Obesity in the Natural History of Type 1 Diabetes Mellitus: Causes and Consequences

  2011cites this paper
• Efek Pemberian Niasin terhadap Glukosa Darah pada Tikus Wistar dengan Obesitas

  2011cites this paper
• Anti-diabetic effect of trigonelline and nicotinic acid, on KK-A(y) mice.

  2010cites this paper
• [Not Available].

  2010cites this paper
• [Drug-induced hyperglycemia: a study in the French pharmacovigilance database].

  2010cites this paper
• An examination of β‐cell function measures and their potential use for estimating β‐cell mass

  2008cites this paper
• Nicotinic acid: pharmacological effects and mechanisms of action.

  2008cites this paper
• Nicotinic acid: an old drug with a promising future

  2008cites this paper
• Niacin in the metabolic syndrome: more risk than benefit?

  2006cites this paper
• [Insulin resistance and metabolic syndrome in type 1 diabetes mellitus].

  2006cites this paper
• A natural sweetener, Momordica grosvenori, attenuates the imbalance of cellular immune functions in alloxan‐induced diabetic mice

  2006cites this paper
• Perspectives in Diabetes Prediction and Prevention of IDDM-1991

  2006cites this paper
• Effects of short-term experimental insulin resistance and family history of diabetes on pancreatic beta-cell function in nondiabetic individuals.

  2005cites this paper
• Nonhuman primate models for islet transplantation in type 1 diabetes research.

  2004cites this paper
• Insulin resistance in type 1 diabetes

  2002cites this paper
• Impaired beta-cell function, incretin effect, and glucagon suppression in patients with type 1 diabetes who have normal fasting glucose.

  2002cites this paper
• Insulin and Glucagon Secretion in vivo and its Neural Control

  2001cites this paper
• Co-administration of equimolar doses of betaine may alleviate the hepatotoxic risk associated with niacin therapy.

  2000cites this paper
• Insulin secretion in growth hormone-deficient adults: effects of 24 months' therapy and five days' acute withdrawal of recombinant human growth hormone.

  1999cites this paper
• Beta-cell behaviour during the prediabetic stage. Part II. Non-insulin-dependent and insulin-dependent diabetes mellitus.

  1997cites this paper
• Effects of ketamine sedation on glucose clearance, insulin secretion and counterregulatory hormone production in baboons (Papio hamadryas)

  1997cites this paper
• Acipimox attenuates hypertriglyceridemia in dyslipidemic noninsulin dependent diabetes mellitus patients without perturbation of insulin sensitivity and glycemic control.

  1997cites this paper
• Nicotinamide's Effects on Glucose Metabolism in Subjects at Risk For IDDM

  1996cites this paper
• Impact of nicotinic acid treatment on insulin secretion and insulin sensitivity in low and high insulin responders.

  1996cites this paper
• A baboon (Papio hamadryas) model of insulin‐dependent diabetes

  1995cites this paper
• Niacin: a therapeutic dilemma. "One man's drink is another's poison".

  1994cites this paper
• Disproportionately elevated proinsulin levels precede the onset of insulin-dependent diabetes mellitus in siblings with low first phase insulin responses. The Childhood Diabetes in Finland Study Group.

  1994cites this paper
• Helminthic infestation complicated by intussusception in baboons (Papio hamadryas)

  1994cites this paper
• High Genetic Risk for IDDM in the Pacific Northwest: First Report From the Washington State Diabetes Prediction Study

  1994cites this paper
• Drug-Induced Disorders of Glucose Tolerance

  1993cites this paper
• Nicotinamide and insulin secretion in normal subjects

  1993influential citation
• Effect of insulin resistance and hyperglycemia on proinsulin release in a primate model of diabetes mellitus.

  1992cites this paper
• Effects of prolonged Acipimox treatment on glucose and lipid metabolism and on in vivo insulin sensitivity in patients with non-insulin dependent diabetes mellitus.

  1992cites this paper
• Prediction and Prevention of IDDM—1991

  1991cites this paper