The effects of sodium sulfate, glycosaminoglycans, and Congo red on the structure, stability, and amyloid formation of an immunoglobulin light‐chain protein

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Protein Science

• Publication date

  2006-07-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1110/ps.051997606PMID 16751605PMCID PMC2242560
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosis.

  2005cited by this paper
• Critical balance of electrostatic and hydrophobic interactions is required for beta 2-microglobulin amyloid fibril growth and stability.

  2005cited by this paper
• Kinetic analysis of the polymerization and depolymerization of beta(2)-microglobulin-related amyloid fibrils in vitro.

  2005cited by this paper
• Amyloid accomplices and enforcers

  2005cited by this paper
• Cellular response of cardiac fibroblasts to amyloidogenic light chains.

  2005influential reference
• Seeding-dependent Maturation of β2-Microglobulin Amyloid Fibrils at Neutral pH*

  2005influential reference
• Inhibition of amyloid A amyloidogenesis in vivo and in tissue culture by 4-deoxy analogues of peracetylated 2-acetamido-2-deoxy-alpha- and beta-d-glucose: implications for the treatment of various amyloidoses.

  2004cited by this paper
• The effect of macromolecular crowding on protein aggregation and amyloid fibril formation

  2004cited by this paper
• Functional structure and composition of the extracellular matrix

  2003cited by this paper
• Diseases of protein conformation: what do in vitro experiments tell us about in vivo diseases?

  2003cited by this paper
• Mutations in the B1 domain of protein G that delay the onset of amyloid fibril formation in vitro

  2003cited by this paper
• Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated amyloidosis (AL).

  2003cited by this paper
• Congo Red Populates Partially Unfolded States of an Amyloidogenic Protein to Enhance Aggregation and Amyloid Fibril Formation*

  2003cited by this paper
• Amyloidogenesis: historical and modern observations point to heparan sulfate proteoglycans as a major culprit

  2003cited by this paper
• Apolipoprotein E, amyloid, and Alzheimer disease.

  2002cited by this paper
• Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from alpha-synuclein in vitro.

  2002cited by this paper
• Establishment of a first-order kinetic model of light chain-associated amyloid fibril extension in vitro.

  2002cited by this paper
• Pathogenesis, diagnosis and treatment of systemic amyloidosis.

  2001cited by this paper
• Examining the structure of the mature amyloid fibril.

  2001cited by this paper
• Review: history of the amyloid fibril.

  2000cited by this paper
• Review: Modulating Factors in Amyloid-β Fibril Formation

  2000cited by this paper
• Review: modulating factors in amyloid-beta fibril formation.

  2000cited by this paper
• The Sulfate Moieties of Glycosaminoglycans Are Critical for the Enhancement of β‐Amyloid Protein Fibril Formation

  1999cited by this paper
• Interactions of Alzheimer amyloid-beta peptides with glycosaminoglycans effects on fibril nucleation and growth.

  1999cited by this paper
• Amyloidosis.

  1999cited by this paper
• Thermodynamic instability of human lambda 6 light chains: correlation with fibrillogenicity.

  1999cited by this paper
• Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins.

  1997cited by this paper
• Interaction between glycosaminoglycans and immunoglobulin light chains.

  1997cited by this paper
• The systemic amyloidoses.

  1997cited by this paper
• The acid-mediated denaturation pathway of transthyretin yields a conformational intermediate that can self-assemble into amyloid.

  1996cited by this paper
• Sulfonated dyes attenuate the toxic effects of β-amyloid in a structure-specific fashion

  1995cited by this paper
• Sulfonated dyes attenuate the toxic effects of beta-amyloid in a structure-specific fashion.

  1995cited by this paper
• Recombinant immunoglobulin variable domains generated from synthetic genes provide a system for in vitro characterization of light‐chain amyloid proteins

  1994cited by this paper
• Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

  1994cited by this paper
• Rapid induction of Alzheimer A beta amyloid formation by zinc.

  1994cited by this paper
• Congo red protects against toxicity of beta-amyloid peptides on rat hippocampal neurones.

  1994cited by this paper
• MEASURING THE CONFORMATIONAL STABILITY OF PROTEINS

  1992cited by this paper
• Glycosaminoglycans of the hemodialysis-associated carpal synovial amyloid and of amyloid-rich tissues and fibrils of heart, liver, and spleen.

  1990influential reference
• Amyloid enhancing factor-loaded macrophages in amyloid fibril formation.

  1990cited by this paper
• Induction of amyloid enhancing factor and its biological properties in murine alveolar hydatidosis.

  1988cited by this paper
• Primary systemic amyloidosis: multivariate analysis for prognostic factors in 168 cases.

  1986cited by this paper
• Temporal relationship between glycosaminoglycan accumulation and amyloid deposition during experimental amyloidosis. A histochemical study.

  1985cited by this paper
• Amyloid enhancing factor in hamster.

  1985cited by this paper
• Amyloid proteins, precursors, mediator, and enhancer.

  1983cited by this paper
• Amyloidosis: a familiar problem in the light of current pathogenetic developments.

  1983cited by this paper
• Further characterization of amyloid-enhancing factor.

  1982cited by this paper
• Transfer amyloidosis.

  1976cited by this paper
• Transfer amyloidosis.

  1973influential reference
• Amyloidosis

  1933cited by this paper

• Role of extracellular space and matrix remodeling in cardiac amyloidosis.

  2025cites this paper
• Effect of dynamic exclusion and the use of FAIMS, DIA and MALDI-mass spectrometry imaging with ion mobility on amyloid protein identification

  2024cites this paper
• Amyloid-Induced Neurodegeneration: A Comprehensive Review through Aggregomics Perception of Proteins in Health and Pathology.

  2024cites this paper
• Producing amyloid fibrils in vitro: A tool for studying AL amyloidosis

  2023cites this paper
• Functionalised penetrating peptide-chondroitin sulphate‑gold nanoparticles: Synthesis, characterization, and applications as an anti-Alzheimer's disease drug.

  2023cites this paper
• Prospective Role of Citicoline and Hyaluronated Nanotechnology as Drug Delivery A pproaches for Alzheimer’s Disease: Review of the Literature

  2022cites this paper
• From the Light Chain Sequence to the Tissue Microenvironment: Contribution of the Mesangial Cells to Glomerular Amyloidosis

  2022cites this paper
• Chondroitin sulfate E alleviates β-amyloid toxicity in transgenic Caenorhabditis elegans by inhibiting its aggregation.

  2022cites this paper
• The influence of cations on α-lactalbumin amyloid aggregation

  2022cites this paper
• A biphasic response of polymerized Type 1 collagen architectures to dermatan sulfate.

  2021cites this paper
• Therapeutic Potential and Main Methods of Obtaining Selenium Nanoparticles

  2021cites this paper
• Analysis of gene expression profiling of amyloidogenic immunoglobulin light-chains on cultured rat cardiomyocytes

  2020cites this paper
• Understanding Mesangial Pathobiology in AL-Amyloidosis and Monoclonal Ig Light Chain Deposition Disease

  2020cites this paper
• Polyunsaturated fatty acid deficiency affects sulfatides and other sulfated glycans in lysosomes through autophagy‐mediated degradation

  2020cites this paper
• Preparation and in vitro evaluation of multi-target-directed selenium-chondroitin sulfate nanoparticles in protecting against the Alzheimer's disease.

  2019cites this paper
• Low-molecular-weight chondroitin sulfate attenuated injury by inhibiting oxidative stress in amyloid &bgr;-treated SH-SY5Y cells

  2018cites this paper
• Isolation and purification of recombinant immunoglobulin light chain variable domains from the periplasmic space of Escherichia coli

  2018cites this paper
• Immunoglobulin light chain amyloid aggregation.

  2018cites this paper
• 1 Current and New Perspectives on the Molecular and Cellular Mechanisms of Amyloid Formation and Toxicity in Light Chain Amyloidosis

  2018cites this paper
• Modulation of amyloid assembly by glycosaminoglycans: from mechanism to biological significance.

  2017cites this paper
• Tau Pathology Promotes the Reorganization of the Extracellular Matrix and Inhibits the Formation of Perineuronal Nets by Regulating the Expression and the Distribution of Hyaluronic Acid Synthases

  2017cites this paper
• Sulfated glycosaminoglycans in protein aggregation diseases

  2017cites this paper
• Immunoglobulin Light Chains Form an Extensive and Highly Ordered Fibril Involving the N- and C-Termini

  2017cites this paper
• Neuroprotective effect of chondroitin sulfate on SH-SY5Y cells overexpressing wild-type or A53T mutant α-synuclein

  2017cites this paper
• Solid-state NMR chemical shift assignments for AL-09 VL immunoglobulin light chain fibrils

  2017cites this paper
• Critical Influence of Cosolutes and Surfaces on the Assembly of Serpin-Derived Amyloid Fibrils.

  2017cites this paper
• The Effect of Milk Constituents and Crowding Agents on Amyloid Fibril Formation by κ-Casein.

  2016cites this paper
• Solid-state NMR chemical shift assignments for AL-09 VL immunoglobulin light chain fibrils

  2016cites this paper
• Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate*

  2016cites this paper
• Probing the role of λ6 immunoglobulin light chain dimerization in amyloid formation.

  2016cites this paper
• The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains.

  2016cites this paper
• Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes

  2015cites this paper
• Protective effects of low molecular weight chondroitin sulfate on amyloid beta (Aβ)-induced damage in vitro and in vivo.

  2015cites this paper
• Mutations can cause light chains to be too stable or too unstable to form amyloid fibrils

  2015cites this paper
• A carboxylated Zn‐phthalocyanine inhibits fibril formation of Alzheimer's amyloid β peptide

  2015cites this paper
• Mass spectrometry studies of immunoglobulins

  2015influential citation
• The Structural Determinants of the Immunoglobulin Light Chain Amyloid Aggregation

  2015cites this paper
• The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity

  2015cites this paper
• Nanoliposomes protect against AL amyloid light chain protein-induced endothelial injury

  2014cites this paper
• Sulfate anion delays the self-assembly of human insulin by modifying the aggregation pathway.

  2014cites this paper
• Divergent effect of glycosaminoglycans on the in vitro aggregation of serum amyloid A.

  2014cites this paper
• Kinetic control in protein folding for light chain amyloidosis and the differential effects of somatic mutations.

  2014cites this paper
• Differential Effects on Light Chain Amyloid Formation Depend on Mutations and Type of Glycosaminoglycans*

  2014cites this paper
• Interplay of Sequence, Topology and Termini Charge in Determining the Stability of the Aggregates of GNNQQNY Mutants: A Molecular Dynamics Study

  2014cites this paper
• Molecular determinants and mechanisms of antibody light chain (AL) amyloidosis

  2014cites this paper
• Mécanisme d'association de deux protéines amyloïdogènes de l'héparane sulfate protéoglycane. Rôle du pH et de l'activité protéasique de la transthyrétine

  2014cites this paper
• Distinction of Coexisting Protein Conformations by Capillary Electrophoresis

  2013cites this paper
• Thermal Stability Threshold for Amyloid Formation in Light Chain Amyloidosis

  2013cites this paper
• Role of mutations in the cellular internalization of amyloidogenic light chains into cardiomyocytes

  2013cites this paper
• light chain-secreting human cell lines, ALMC-1 and ALMC-2 Biologic and genetic characterization of the novel amyloidogenic lambda

  2013cites this paper
• Amyloid formation in light chain amyloidosis.

  2013cites this paper
• Serum Amyloid A (SAA): Proinflammatory functions and their regulation by serum lipoproteins

  2012cites this paper
• Glycosaminoglycans (GAGs) suppress the toxicity of HypF-N prefibrillar aggregates.

  2012cites this paper
• In Vitro Aggregation Behavior of a Non-Amyloidogenic λ Light Chain Dimer Deriving from U266 Multiple Myeloma Cells

  2012cites this paper
• Tyrosine Residues Mediate Fibril Formation in a Dynamic Light Chain Dimer Interface

  2012cites this paper
• Protein delivery using mesoporous ceramic/polymer hybrid.

  2011cites this paper
• Current and New Perspectives on the Molecular and Cellular Mechanisms of Amyloid Formation and Toxicity in Light Chain Amyloidosis

  2011cites this paper
• Glycosaminoglycans promote fibril formation by amyloidogenic immunoglobulin light chains through a transient interaction.

  2011cites this paper
• Stability and aggregation kinetics of colloidal systems: application to polymer colloids, proteins and peptides

  2011cites this paper
• Sulfated glycosaminoglycans accelerate transthyretin amyloidogenesis by quaternary structural conversion.

  2011cites this paper
• Investigating the effects of sodium dodecyl sulfate on the aggregative behavior of hen egg-white lysozyme at acidic pH.

  2010cites this paper
• Pathogenesis of Systemic Amyloidoses

  2010cites this paper
• Comparison of amyloid fibril formation by two closely related immunoglobulin light chain variable domains

  2010cites this paper
• A single mutation promotes amyloidogenicity through a highly promiscuous dimer interface.

  2010cites this paper
• A Computational Approach for Identifying the Chemical Factors Involved in the Glycosaminoglycans-Mediated Acceleration of Amyloid Fibril Formation

  2010cites this paper
• Role of Glycosaminoglycan Sulfation in the Formation of Immunoglobulin Light Chain Amyloid Oligomers and Fibrils*

  2010cites this paper
• The critical role of the constant region in thermal stability and aggregation of amyloidogenic immunoglobulin light chain.

  2010cites this paper
• Role of proteoglycans and glycosaminoglycans in the pathogenesis of Alzheimer's disease and related disorders: Amyloidogenesis and therapeutic strategies—A review

  2010cites this paper
• Cytotoxicity of amyloidogenic immunoglobulin light chains in cell culture

  2010cites this paper
• Structural alterations within native amyloidogenic immunoglobulin light chains.

  2009cites this paper
• Light chain amyloidosis - current findings and future prospects.

  2009cites this paper
• Amyloid formation by the model protein muscle acylphosphatase is accelerated by heparin and heparan sulphate through a scaffolding-based mechanism.

  2009cites this paper
• Hen egg white lysozyme fibrillation: a deep‐UV resonance Raman spectroscopic study

  2008cites this paper
• Altered Dimer Interface Decreases Stability in an Amyloidogenic Protein*

  2008cites this paper
• Salts enhance both protein stability and amyloid formation of an immunoglobulin light chain.

  2008influential citation
• Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains

  2008cites this paper
• Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2.

  2008cites this paper
• 2D correlation deep UV resonance raman spectroscopy of early events of lysozyme fibrillation: kinetic mechanism and potential interpretation pitfalls.

  2008cites this paper
• Principles of protein misfolding.

  2008cites this paper
• Structural Insights into the Role of Mutations in Amyloidogenesis*

  2008cites this paper
• Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases.

  2008cites this paper
• Immunoglobulin Light Chain and Systemic Light-Chain Amyloidosis

  2007cites this paper
• Kinetics of amyloid formation and membrane interaction with amyloidogenic proteins.

  2007cites this paper
• The first step of hen egg white lysozyme fibrillation, irreversible partial unfolding, is a two‐state transition

  2007cites this paper
• Structural Evolution of Immunoglobulin Light Chain during Amyloid Fibril Formation: A Deep Uv Resonance Raman Spectroscopic Study

  2007cites this paper