Staphylococcal protein A inhibited phagocytosis of Staphylococcus aureus and Escherichia coli in in vitro phagocytosis systems with normal human serum. Protein A had no effect on phagocytic cells per se, and produced inhibition of the heat labile opsonins, i.e., of the complement system in normal sera at low concentration. At higher concentration of protein A there was little complement fixation and little inhibition of serum opsonic activity.
Effects of staphylococcal protein A on heat labile opsonins.
Published 1974 in Journal of Immunology
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- Publication year
1974
- Venue
Journal of Immunology
- Publication date
1974-03-01
- Fields of study
Biology, Medicine, Chemistry
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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