Continuous cyclic stretch induces osteoblast alignment and formation of anisotropic collagen fiber matrix.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Acta Biomaterialia

• Publication date

  2013-07-01

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1016/j.actbio.2013.03.015PMID 23523937
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Surface acoustic wave induced particle manipulation in a PDMS channel—principle concepts for continuous flow applications

  2012cited by this paper
• The alignment of MC3T3-E1 osteoblasts on steps of slip traces introduced by dislocation motion.

  2012cited by this paper
• Cyclic strain anisotropy regulates valvular interstitial cell phenotype and tissue remodeling in three-dimensional culture.

  2012cited by this paper
• Biological apatite (BAp) crystallographic orientation and texture as a new index for assessing the microstructure and function of bone regenerated by tissue engineering.

  2012cited by this paper
• Visualizing cell extracellular matrix (ECM) deposited by cells cultured on aligned bacteriophage M13 thin films.

  2011cited by this paper
• The Amazing Osteocyte

  2010cited by this paper
• A Dynamic Stochastic Model of Frequency-Dependent Stress Fiber Alignment Induced by Cyclic Stretch

  2009cited by this paper
• Mechanotransduction in osteoblast regulation and bone disease.

  2009cited by this paper
• A primary role for Golgi positioning in directed secretion, cell polarity, and wound healing.

  2009cited by this paper
• Passive flow-rate regulators using pressure-dependent autonomous deflection of parallel membrane valves.

  2009cited by this paper
• Effects of Cell Seeding and Cyclic Stretch on the Fiber Remodeling in an Extracellular Matrix–Derived Bioscaffold

  2008cited by this paper
• Collagen fibrillogenesis: fibronectin, integrins, and minor collagens as organizers and nucleators

  2008cited by this paper
• Two characteristic regimes in frequency-dependent dynamic reorientation of fibroblasts on cyclically stretched substrates.

  2008cited by this paper
• Mechanical stress‐mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts

  2007cited by this paper
• Effect of Strain Magnitude on the Tissue Properties of Engineered Cardiovascular Constructs

  2007cited by this paper
• Dynamic Fibroblast Cultures

  2007cited by this paper
• Stretch‐induced modulation of matrix metalloproteinases in mineralizing osteoblasts via extracellular signal‐regulated kinase‐1/2

  2006cited by this paper
• Effects of different magnitudes of mechanical strain on Osteoblasts in vitro.

  2006cited by this paper
• Cyclic strain increases fibroblast proliferation, matrix accumulation, and elastic modulus of fibroblast-seeded polyurethane constructs.

  2006cited by this paper
• Tissue Reorganization in Response to Mechanical Load Increases Functionality

  2005cited by this paper
• Quantitative evaluation of threshold fiber strain that induces reorganization of cytoskeletal actin fiber structure in osteoblastic cells.

  2005cited by this paper
• Alignment of Osteoblast-Like Cells and Cell-Produced Collagen Matrix Induced by Nanogrooves

  2005cited by this paper
• Effects of Cyclic Tensile Forces on the Expression of Vascular Endothelial Growth Factor (VEGF) and Macrophage-colony-stimulating Factor (M-CSF) in Murine Osteoblastic MC3T3-E1 Cells

  2005cited by this paper
• Stretch‐induced phosphorylation of ERK1/2 depends on differentiation stage of osteoblasts

  2004cited by this paper
• Intermittent versus continuous stretching effects on osteoblast-like cells in vitro.

  2003cited by this paper
• Cell orientation determines the alignment of cell-produced collagenous matrix.

  2003cited by this paper
• Fluid flow shear stress stimulates human osteoblast proliferation and differentiation through multiple interacting and competing signal transduction pathways.

  2003cited by this paper
• Unique alignment and texture of biological apatite crystallites in typical calcified tissues analyzed by microbeam X-ray diffractometer system.

  2002cited by this paper
• Experiments with osteoblasts cultured under varying orientations with respect to the gravity vector

  2002cited by this paper
• Regulation of expression and activity of four PKC isozymes in confluent and mechanically stimulated UMR‐108 osteoblastic cells

  2001cited by this paper
• Cell alignment is induced by cyclic changes in cell length: studies of cells grown in cyclically stretched substrates

  2001cited by this paper
• How is a tissue built?

  2000cited by this paper
• Mechanical stretching of human osteoblast-like cells stimulates bone morphogenic proteins and macrophage colony-stimulating factor productions

  1999cited by this paper
• Microstructure-microhardness relations in parallel-fibered and lamellar bone.

  1996cited by this paper
• Osteonal structure in the equine third metacarpus.

  1996cited by this paper
• Mechanical stimulation by intermittent hydrostatic compression promotes bone-specific gene expression in vitro.

  1995cited by this paper
• The strength of a calcified tissue depends in part on the molecular structure and organization of its constituent mineral crystals in their organic matrix.

  1995cited by this paper
• Mechanotransduction in bone: do bone cells act as sensors of fluid flow?

  1994cited by this paper
• A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses.

  1994cited by this paper
• Effect of a continuously applied compressive pressure on mouse osteoblast‐like cells (MC3T3‐E1) in vitro

  1990cited by this paper
• Tensile forces enhance prostaglandin E synthesis in osteoblastic cells grown on collagen ribbons

  1984cited by this paper
• Circular statistics in biology

  1981cited by this paper
• Orientation of apatite crystals in relation to muscle attachment in the mandible.

  1980cited by this paper
• Biochemical effect of mechanical stress on cultured bone cells

  1976cited by this paper

• Static mechanical stretch induces collective alignment of C2C12 myoblasts

  2026cites this paper
• Anisotropic Materials Design —From Heat-resistant Intermetallic Compounds to Bone Tissue Microstructure and Biomaterials via. Metal 3DP—

  2025cites this paper
• Cyclic stretch Promotes osteogenesis of osteoblasts via ACh/α7nAChR pathway.

  2025cites this paper
• Molten stringing 3D printed microfibrous net-integrated mineralized hydrogels with tunable micromechanical and cell-responsive properties.

  2025cites this paper
• Effects of thread design on soft and hard tissue healing around implants in lipopolysaccharide-induced peri-implantitis-like lesions in rat maxillae.

  2025cites this paper
• A Mechanically Stimulated Co-culture in 3-Dimensional Composite Scaffolds Promotes Osteogenic and Anti-osteoclastogenic Activity and M2 Macrophage Polarization

  2025cites this paper
• The effects of mechanical stimulation on the morphology and function of spinal ligament cells

  2025cites this paper
• Orthogonal alignment of multilayered MC3T3-E1 cells induced by cyclic stretch

  2025cites this paper
• Microcomputed tomographic analysis of the trabecular and cortical architecture of the proximal femur and hip bone of cats and small breed dogs.

  2025cites this paper
• An in silico study reveals how architectural and mechanical cues jointly regulate angiogenesis and bone regeneration in 3D printed scaffolds

  2025cites this paper
• Effects of polylactic acid scaffolds with various orientations and diameters on osteogenesis and angiogenesis

  2025cites this paper
• Nanocomposite magnetic hydrogel with dual anisotropic properties induces osteogenesis through the NOTCH-dependent pathways

  2024cites this paper
• Osteogenic tailoring of oriented bone matrix organization using on/off micropatterning for osteoblast adhesion on titanium surfaces.

  2024cites this paper
• Long range juxtacrine signalling through cadherin for collective cell orientation.

  2024cites this paper
• Responses of osteoblasts under varied tensile stress types induced by stretching basement materials

  2024cites this paper
• PBF-LB fabrication of microgrooves for induction of osteogenic differentiation of human mesenchymal stem cells

  2024cites this paper
• Mechanical stretching determines the orientation of osteoblast migration and cell division

  2023cites this paper
• Fabrication of a Magnetically Driven Cell-Stretching Device for Predefined Cell Alignment in Vitro

  2023cites this paper
• Cell orientation under stretch: A review of experimental findings and mathematical modelling.

  2023cites this paper
• Characterization of three‐dimensional bone‐like tissue growth and organization under influence of directional fluid flow

  2023cites this paper
• Effect of Uniaxial Compression Frequency on Osteogenic Cell Responses in Dynamic 3D Cultures

  2023cites this paper
• Angiogenesis and Re-endothelialization in decellularized scaffolds: Recent advances and current challenges in tissue engineering

  2023cites this paper
• A Novel Ex Vivo Bone Culture Model for Regulation of Collagen/Apatite Preferential Orientation by Mechanical Loading

  2022cites this paper
• Delivering Mechanical Stimulation to Cells: State of the Art in Materials and Devices Design

  2022cites this paper
• Effects of different physical factors on osteogenic differentiation.

  2022cites this paper
• Innovative design of bone quality-targeted intervertebral spacer: Accelerated functional fusion guiding oriented collagen/apatite microstructure without autologous bone graft.

  2022cites this paper
• Investigation of mechanosensing and mechanoresponse mechanisms in osteoblasts and osteocytes: in vitro experiments targeting subcellular components

  2022cites this paper
• Characterization of three-dimensional bone-like tissue growth and organization under influence of curvature and directional fluid flow

  2022cites this paper
• A mechanistic motor-clutch model that explains cell shape dynamics to cyclic stretch

  2022cites this paper
• Engineering collagen fiber templates with oriented nanoarchitecture and concerns on osteoblast behaviors.

  2021cites this paper
• Uniaxially fixed mechanical boundary condition elicits cellular alignment in collagen matrix with induction of osteogenesis

  2021cites this paper
• An in-silico Investigation Into the Role of Strain and Structure on Vascular Smooth Muscle Cell Growth

  2021cites this paper
• Cell stretchers and the LINC complex in mechanotransduction.

  2021cites this paper
• Hydroxyapatite Nanoparticles Facilitate Osteoblast Differentiation and Bone Formation Within Sagittal Suture During Expansion in Rats

  2021cites this paper
• Control of Bone Matrix Properties by Osteocytes

  2021cites this paper
• Design of a 3D printed, motorized, uniaxial cell stretcher for microscopic and biochemical analysis of mechanotransduction

  2021cites this paper
• 3D Cell Culture for the Study of Microenvironment-Mediated Mechanostimuli to the Cell Nucleus: An Important Step for Cancer Research

  2021cites this paper
• DDDT_A_299641 905..917

  2021cites this paper
• Control of osteoblast arrangement by osteocyte mechanoresponse through prostaglandin E2 signaling under oscillatory fluid flow stimuli.

  2021cites this paper
• Control of Stem Cell Fate and Function by Engineered Surface Topography Using Metal Additive Manufacturing Technology

  2021cites this paper
• Effects of actuation of nanoporous gold on cell orientation in a fibroblast sheet

  2021cites this paper
• 3D nanoscale analysis of bone healing around degrading Mg implants evaluated by X-ray scattering tensor tomography.

  2021cites this paper
• Superior Alignment of Human iPSC-Osteoblasts Associated with Focal Adhesion Formation Stimulated by Oriented Collagen Scaffold

  2021cites this paper
• Development of orthophosphosilicate glass/poly(lactic acid) composite anisotropic scaffolds for simultaneous reconstruction of bone quality and quantity

  2020cites this paper
• Design and fabrication of Ti-Zr-Hf-Cr-Mo and Ti-Zr-Hf-Co-Cr-Mo high-entropy alloys as metallic biomaterials.

  2020cites this paper
• Selective patterning of netrin-1 as a novel guiding cue for anisotropic dendrogenesis in osteocytes.

  2020cites this paper
• Recovery of sensory function after the implantation of oriented-collagen tube into the resected rat sciatic nerve

  2020cites this paper
• Bone apatite anisotropic structure control via designing fibrous scaffolds

  2020cites this paper
• Mechanically and Electrically Enhanced Polyurethane-poly(3,4-ethylenedioxythiophene) Conductive Foams with Aligned Pore Structures Promote MC3T3-E1 Cell Growth and Proliferation

  2020cites this paper
• Quantitative Phosphoproteomics Reveals Cell Alignment and Mitochondrial Length Change under Cyclic Stretching in Lung Cells

  2020cites this paper
• 3D Printing of Anisotropic Bone-Mimetic Structure with Controlled Fluid Flow Stimuli for Osteocytes: Flow Orientation Determines the Elongation of Dendrites

  2020cites this paper
• 3D nanoscale analysis of bone healing around degrading Mg implants studied by X-ray scattering tensor tomography

  2020cites this paper
• 3D Printing of Biomaterials for Control of Cellular Behaviors

  2020cites this paper
• Development of non-equiatomic Ti-Nb-Ta-Zr-Mo high-entropy alloys for metallic biomaterials

  2019cites this paper
• Shape recovery strain and nanostructures on recovered polyurethane films and their regulation to osteoblasts morphology.

  2019cites this paper
• Oriented siloxane-containing vaterite/poly(lactic acid) composite scaffolds for controlling osteoblast alignment and proliferation

  2019cites this paper
• Accelerated construction of an in vitro model of human periodontal ligament tissue: vacuum plasma combined with fibronectin coating and a polydimethylsiloxane matrix

  2019cites this paper
• Osteoblast Responses to Titanium-Coated Subcellular Scaled Microgrooves.

  2019cites this paper
• Unique arrangement of bone matrix orthogonal to osteoblast alignment controlled by Tspan11-mediated focal adhesion assembly.

  2019cites this paper
• Development of bifunctional oriented bioactive glass/poly(lactic acid) composite scaffolds to control osteoblast alignment and proliferation

  2019cites this paper
• From bone regeneration to three-dimensional in vitro models: tissue engineering of organized bone extracellular matrix

  2019cites this paper
• In Vitro Bone Cell Response to Tensile Mechanical Solicitations: Is There an Optimal Protocol?

  2018cites this paper
• Development of micro mechanical device having two-dimensional array of micro chambers for cell stretching

  2018cites this paper
• Control of cell behaviour through nanovibrational stimulation: nanokicking

  2018cites this paper
• Review: bioreactor design towards generation of relevant engineered tissues: focus on clinical translation

  2018cites this paper
• Computational analysis of cell-mediated remodeling of collagenous tissues

  2018cites this paper
• [Effect of FTY720-P on the differentiation and maturation of MC3T3-E1 cells].

  2018cites this paper
• Modelling The Combined Effects Of Collagen and Cyclic Strain On Cellular Orientation In Collagenous Tissues

  2018cites this paper
• Construction of human induced pluripotent stem cell‐derived oriented bone matrix microstructure by using in vitro engineered anisotropic culture model

  2017cites this paper
• In vitro cyclic compressive loads potentiate early osteogenic events in engineered bone tissue.

  2017cites this paper
• Alteration of osteoblast arrangement via direct attack by cancer cells: New insights into bone metastasis

  2017cites this paper
• Fabrication of oriented hydroxyapatite film by RF magnetron sputtering

  2017cites this paper
• The role of mechanical forces in bone formation : evaluation of long-term responses by osteoblasts to low fluid shear stress in vitro

  2017cites this paper
• Effects of mechanical repetitive load on bone quality around implants in rat maxillae

  2017cites this paper
• Cyclic mechanical stretch contributes to network development of osteocyte-like cells with morphological change and autophagy promotion but without preferential cell alignment in rat

  2017influential citation
• Biomimetic nano-biomaterials for bone repair and regeneration

  2017cites this paper
• Directional Control of Mature Osteoblast Derived from Juvenile Mouse Calvariae

  2017cites this paper
• Control of Cellular Arrangement by Surface Topography Induced by Plastic Deformation

  2016cites this paper
• Hydroxyapatite nanoparticle injectable hydrogel scaffold to support osteogenic differentiation of human mesenchymal stem cells.

  2016cites this paper
• In situ time-series monitoring of collagen fibers produced by standing-cultured osteoblasts using a second-harmonic-generation microscope.

  2016cites this paper
• In Vitro Bone Cell Models: Impact of Fluid Shear Stress on Bone Formation

  2016cites this paper
• Strain magnitude dependent intracellular calcium signaling response to uniaxial stretch in osteoblastic cells

  2015cites this paper
• Abnormal arrangement of a collagen/apatite extracellular matrix orthogonal to osteoblast alignment is constructed by a nanoscale periodic surface structure.

  2015cites this paper
• Bone Tissue and Biomaterial Design Based on the Anisotropic Microstructure

  2015cites this paper
• Bioreactor Technology for Oral and Craniofacial Tissue Engineering

  2015cites this paper
• Powder-based Additive Manufacturing for Development of Tailor-made Implants for Orthopedic Applications

  2015cites this paper
• The influence of anisotropic nano- to micro-topography on in vitro and in vivo osteogenesis.

  2015cites this paper
• Advances in Techniques for Probing Mechanoregulation of Tissue Morphogenesis

  2015cites this paper
• Quantitative regulation of bone-mimetic, oriented collagen/apatite matrix structure depends on the degree of osteoblast alignment on oriented collagen substrates.

  2015cites this paper
• Advances in Metallic Biomaterials: Tissues, Materials and Biological Reactions

  2015cites this paper
• Oriented Collagen Scaffolds for Anisotropic Bone Tissue Construction In Vitro

  2014cites this paper
• Stretchable and micropatterned membrane for osteogenic differentation of stem cells.

  2014cites this paper
• 付加製造技術(3D プリンター)による金属系生体機能性材料の開発

  2014cites this paper
• Control of Oriented Extracellular Matrix Similar to Anisotropic Bone Microstructure

  2014cites this paper