Plasminogen activator‐1 overexpression decreases experimental postthrombotic vein wall fibrosis by a non‐vitronectin‐dependent mechanism

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Journal of Thrombosis and Haemostasis

• Publication date

  2014-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/jth.12644PMID 24943740PMCID PMC4127110
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Low-molecular-weight heparin modulates vein wall fibrotic response in a plasminogen activator inhibitor 1-dependent manner.

  2014cited by this paper
• Compression stockings to prevent post-thrombotic syndrome: a randomised placebo-controlled trial.

  2014cited by this paper
• Deletion of Cysteine-Cysteine Receptor 7 Promotes Fibrotic Injury in Experimental Post-Thrombotic Vein Wall Remodeling

  2014cited by this paper
• Matrix metalloproteinase-9 deletion is associated with decreased mid-term vein wall fibrosis in experimental stasis DVT.

  2013cited by this paper
• The effect of matrix metalloproteinase 2 and matrix metalloproteinase 2/9 deletion in experimental post-thrombotic vein wall remodeling.

  2013cited by this paper
• Impaired fibrinolytic system in ApoE gene-deleted mice with hyperlipidemia augments deep vein thrombosis.

  2012cited by this paper
• The role of urokinase plasminogen activator and plasmin activator inhibitor-1 on vein wall remodeling in experimental deep vein thrombosis.

  2012cited by this paper
• The Biochemistry, Physiology and Pathological roles of PAI-1 and the requirements for PAI-1 inhibition in vivo.

  2012cited by this paper
• Antithrombotic therapy for VTE disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines.

  2012cited by this paper
• Toll-Like Receptor 9 Signaling Is Critical for Early Experimental Deep Vein Thrombosis Resolution

  2011cited by this paper
• Pre‐eminence and persistence of immature natural killer cells in acute myeloid leukemia patients in first complete remission

  2011cited by this paper
• Vitronectin in Vascular Context: Facets of a Multitalented Matricellular Protein

  2011cited by this paper
• An update on etiology, prevention, and therapy of postthrombotic syndrome.

  2011cited by this paper
• The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice.

  2011cited by this paper
• Interleukin-6: a potential target for post-thrombotic syndrome.

  2011cited by this paper
• Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent

  2010cited by this paper
• Vitronectin Increases Vascular Permeability by Promoting VE-Cadherin Internalization at Cell Junctions

  2010cited by this paper
• Urokinase plasminogen activator independent early experimental thrombus resolution: MMP2 as an alternative mechanism

  2010cited by this paper
• Heart disease and stroke statistics--2010 update: a report from the American Heart Association.

  2010cited by this paper
• Executive summary: heart disease and stroke statistics--2010 update: a report from the American Heart Association.

  2010cited by this paper
• Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice.

  2008cited by this paper
• Mechanisms of venous thrombosis and resolution.

  2008cited by this paper
• Vein wall re-endothelialization after deep vein thrombosis is improved with low-molecular-weight heparin.

  2008cited by this paper
• Macrophage activation and polarization.

  2008cited by this paper
• Fibrotic injury after experimental deep vein thrombosis is determined by the mechanism of thrombogenesis

  2007cited by this paper
• Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

  2007cited by this paper
• Pharmacological inhibition of the vitronectin receptor abrogates PDGF-BB-induced hepatic stellate cell migration and activation in vitro.

  2007cited by this paper
• Targeted Deletion of CCR2 Impairs Deep Vein Thombosis Resolution in a Mouse Model12

  2006cited by this paper
• Chronic venous disease.

  2006cited by this paper
• Collagen in the scarless fetal skin wound: Detection with Picrosirius‐polarization

  2005cited by this paper
• Intravitreal plasmin injection activates endogenous matrix metalloproteinase-2 in rabbit and human vitreous.

  2005cited by this paper
• Deep Vein Thrombosis Resolution Is Modulated by Monocyte CXCR2-Mediated Activity in a Mouse Model

  2004cited by this paper
• Plasminogen activator inhibitor-1 impairs alveolar epithelial repair by binding to vitronectin.

  2004cited by this paper
• Renal fibrosis: not just PAI-1 in the sky.

  2003cited by this paper
• Selectins influence thrombosis in a mouse model of experimental deep venous thrombosis.

  2002cited by this paper
• Vitronectin is up-regulated after vascular injury and vitronectin blockade prevents neointima formation.

  2002cited by this paper
• Nitric oxide inhibition increases aortic wall matrix metalloproteinase-9 expression.

  2002cited by this paper
• Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream.

  2002cited by this paper
• Endogenous Vitronectin and Plasminogen Activator Inhibitor-1 Promote Neointima Formation in Murine Carotid Arteries

  2002cited by this paper
• Inflammation and thrombosis: the clot thickens.

  2001cited by this paper
• Plasminogen Activator Inhibitor Type 1 Enhances Neointima Formation After Oxidative Vascular Injury in Atherosclerosis-Prone Mice

  2001cited by this paper
• Vitronectin in the cirrhotic liver: an immunomarker of mature fibrosis.

  2001cited by this paper
• Plasminogen Activator Inhibitor-1 and Its Cofactor Vitronectin Stabilize Arterial Thrombi After Vascular Injury in Mice

  2001cited by this paper
• uPA/plasmin system-mediated MMP-9 activation is implicated in bronchial epithelial cell migration.

  2001cited by this paper
• Nitric oxide inhibition increases matrix metalloproteinase-9 expression by rat aortic smooth muscle cells in vitro.

  2001cited by this paper
• Plasminogen activator inhibitor-1 and vitronectin promote vascular thrombosis in mice.

  2000cited by this paper
• Type 1 Plasminogen Activator Inhibitor Binds to Fibrin via Vitronectin*

  2000cited by this paper
• Mouse models of focal arterial and venous thrombosis

  2000cited by this paper
• Monocyte chemotactic protein-1 (MCP-1) accelerates the organization and resolution of venous thrombi.

  1999cited by this paper
• Vitaxin, a humanized monoclonal antibody to the vitronectin receptor (alphavbeta3), reduces neointimal hyperplasia and total vessel area after balloon injury in hypercholesterolemic rabbits.

  1999cited by this paper
• Vitronectin inhibits the thrombotic response to arterial injury in mice.

  1999cited by this paper
• Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.

  1999cited by this paper
• Novel roles for chemokines and fibroblasts in interstitial fibrosis.

  1998cited by this paper
• Beyond fibrinolysis: the role of plasminogen activator inhibitor-1 and vitronectin in vascular wound healing.

  1998cited by this paper
• Inhibitory role of plasminogen activator inhibitor-1 in arterial wound healing and neointima formation: a gene targeting and gene transfer study in mice.

  1997cited by this paper
• Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene.

  1996cited by this paper
• Relationship between changes in the deep venous system and the development of the postthrombotic syndrome after an acute episode of lower limb deep vein thrombosis: a one- to six-year follow-up.

  1995cited by this paper
• Vitronectin is not essential for normal mammalian development and fertility.

  1995cited by this paper
• Cytokine activation of vascular endothelium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator inhibitor.

  1988cited by this paper
• Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin 1.

  1986cited by this paper
• Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections

  1979cited by this paper

• New horizons in the pharmacological management of venous thromboembolism

  2025cites this paper
• Time-dependent ultrastructural changes during venous thrombogenesis and thrombus resolution.

  2024cites this paper
• Targeting Fibrinolytic Inhibition for Venous Thromboembolism Treatment: Overview of an Emerging Therapeutic Approach.

  2024cites this paper
• Effectiveness of 1α-25-dihydroxyvitamin D3 active substance on anastomosis safety in the rat femoral artery end-to-end anastomosis experimental model: Macroscopic and histological analyses.

  2024cites this paper
• Monocyte/macrophage-mediated venous thrombus resolution

  2024cites this paper
• Progress in Diagnosis and Treatment of Syndrome after Deep Vein Thrombosis in the Lower Limbs

  2024cites this paper
• Evaluation of the Superficial Collecting Lymph Vessels' Vasa Vasorum in Lymphoedematous Limbs Using Video Capillaroscopy.

  2023cites this paper
• LGK974 suppresses the formation of deep vein thrombosis in mice with sepsis.

  2023cites this paper
• がん種の違いによる静脈血栓症の発生機序

  2023cites this paper
• Mechanisms of cancer-associated thrombosis

  2023cites this paper
• Experimental venous thrombus resolution is driven by IL-6 mediated monocyte actions

  2023cites this paper
• Immune cell–mediated venous thrombus resolution

  2023cites this paper
• Crosstalk between septic shock and venous thromboembolism: a bioinformatics and immunoassay analysis

  2023cites this paper
• Current challenges in the prevention and management of post-thrombotic syndrome—towards improved prevention

  2023cites this paper
• Modulation of interleukin-6 and its effect on late vein wall injury in a stasis mouse model of deep vein thrombosis

  2022cites this paper
• Plasminogen activator inhibitor 1 and venous thrombosis in pancreatic cancer.

  2021influential citation
• Fibrinolysis in Venous Thromboembolism

  2021cites this paper
• Resolution of Deep Venous Thrombosis: Proposed Immune Paradigms

  2020cites this paper
• Specific inhibition of plasminogen activator inhibitor 1 reduces blood glucose level by lowering TNF-α.

  2020cites this paper
• Inflammatory biomarkers in deep venous thrombosis organization, resolution, and post-thrombotic syndrome.

  2020cites this paper
• Thrombo-Inflammation in Cardiovascular Disease: An Expert Consensus Document from the Third Maastricht Consensus Conference on Thrombosis

  2020cites this paper
• Insights from experimental post-thrombotic syndrome and potential for novel therapies.

  2020cites this paper
• siRNA‐mediated silencing of PAI‐1 gene acts as a promoter over the recanalization of endothelial progenitor cells in rats with venous thrombosis

  2019cites this paper
• Improved Immuno-PET Imaging of HER2-Positive Tumors in Mice: Urokinase Injection-Triggered Clearance Enhancement of 64Cu-Trastuzumab.

  2019cites this paper
• Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease

  2019cites this paper
• Fibrinolysis and Inflammation in Venous Thrombus Resolution

  2019cites this paper
• Venous Thrombosis and Post-Thrombotic Syndrome: From Novel Biomarkers to Biology.

  2018cites this paper
• Urokinase injection‐triggered clearance enhancement of a 4‐arm PEG‐conjugated 64Cu‐bombesin analog tetramer: A novel approach for the improvement of PET imaging contrast

  2018cites this paper
• Serpins in Venous Thrombosis and Venous Thrombus Resolution.

  2018cites this paper
• TGF-β1 in Vascular Wall Pathology: Unraveling Chronic Venous Insufficiency Pathophysiology

  2017cites this paper
• Endotoxaemia-augmented murine venous thrombosis is dependent on TLR-4 and ICAM-1, and potentiated by neutropenia

  2016cites this paper
• FROM BENCH TO BEDSIDE From the American Venous Forum

  2016cites this paper
• Expression of P-selectin , VCAM-1 , and PSGL-1 in traumatic deep venous thrombosis

  2016cites this paper
• The post thrombotic syndrome: Ignore it and it will come back to bite you.

  2016cites this paper
• Gram-Negative Pneumonia Alters Large-Vein Cell-Adhesion Molecule Profile and Potentiates Experimental Stasis Venous Thrombosis

  2016cites this paper
• Libby amphibole‐induced mesothelial cell autoantibodies bind to surface plasminogen and alter collagen matrix remodeling

  2016cites this paper
• Alterations in macrophage phenotypes in experimental venous thrombosis.

  2016cites this paper
• Divergent effects of Tlr9 deletion in experimental late venous thrombosis resolution and vein wall injury

  2015cites this paper
• Venous thrombosis

  2015cites this paper